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ONTOLOGY REPORT - ANNOTATIONS

Term:semi-lunar valve development
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Accession:GO:1905314 term browser browse the term
Definition:The process whose specific outcome is the progression of a semi-lunar valve over time, from its formation to the mature structure.
Synonyms:exact_synonym: semilunar valve development;   semilunar valves development


show annotations for term's descendants           Sort by:
semi-lunar valve development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO (MGI:2429424|PMID:12441304), (MGI:3851675|PMID:19409885) RGD PMID:12441304 PMID:19409885 MGI:2429424 MGI:3851675 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809 		JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 involved_in ISO (MGI:5319103|PMID:22300732) RGD PMID:22300732 MGI:5319103 NCBI chr18:74,046,422...74,156,041
Ensembl chr18:74,046,904...74,156,028 		JBrowse link
aortic valve development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:3640731|PMID:16730346)		 Ensembl
RGD		 PMID:16730346 GO_REF:0000107 MGI:3640731 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO GO:1905314 (MGI:2429424|PMID:12441304) RGD PMID:12441304 MGI:2429424 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809 		JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 involved_in ISO (MGI:5319103|PMID:22300732) RGD PMID:22300732 MGI:5319103 NCBI chr18:74,046,422...74,156,041
Ensembl chr18:74,046,904...74,156,028 		JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region involved_in ISO (MGI:6158728|PMID:26491108) RGD PMID:26491108 MGI:6158728 NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353 		JBrowse link
G Tbx20 T-box transcription factor 20 involved_in ISO (MGI:3604925|PMID:15843409) RGD PMID:15843409 MGI:3604925 NCBI chr 8:23,200,104...23,258,218
Ensembl chr 8:23,204,507...23,258,175 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A involved_in ISO UniProtKB:P25119 (MGI:6158728|PMID:26491108) RGD PMID:26491108 MGI:6158728 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B involved_in ISO UniProtKB:P25118 (MGI:6158728|PMID:26491108) RGD PMID:26491108 MGI:6158728 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206 		JBrowse link
aortic valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdh11 cadherin 11 involved_in ISO UniProtKB:P61586 (PMID:26188246) RGD PMID:26188246 NCBI chr19:2,148,447...2,305,754
Ensembl chr19:2,148,458...2,304,272 		JBrowse link
G Rhoa ras homolog family member A involved_in ISO
IEA		 UniProtKB:F1RFU7 (PMID:26188246)
GO_REF:0000107		 RGD
Ensembl		 PMID:26188246 GO_REF:0000107 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746 		JBrowse link
aortic valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts19 ADAM metallopeptidase with thrombospondin type 1 motif, 19 involved_in ISO (PMID:31844321), (PMID:32323311) RGD PMID:31844321 PMID:32323311 NCBI chr18:52,346,448...52,531,245
Ensembl chr18:52,347,428...52,530,509 		JBrowse link
G Adamts5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 involved_in ISO (MGI:5693221|PMID:23531444) RGD PMID:23531444 MGI:5693221 NCBI chr11:25,000,627...25,047,205
Ensembl chr11:25,000,637...25,047,205 		JBrowse link
G Axin2 axin 2 involved_in IEA
ISO		 GO_REF:0000107
(MGI:6108194|PMID:28069701)		 Ensembl
RGD		 PMID:28069701 GO_REF:0000107 MGI:6108194 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in IEA
ISO		 GO_REF:0000107
(MGI:3039210|PMID:15070745), (MGI:3814273|PMID:18924235)		 Ensembl
RGD		 PMID:15070745 PMID:18924235 GO_REF:0000107 MGI:3039210 MGI:3814273 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Dll4 delta like canonical Notch ligand 4 involved_in ISO
IEA		 (PMID:26491108)
GO_REF:0000107		 RGD
Ensembl		 PMID:26491108 GO_REF:0000107 NCBI chr 3:106,317,114...106,327,004
Ensembl chr 3:106,316,986...106,326,931 		JBrowse link
G Efna1 ephrin A1 involved_in ISO (MGI:4847981|PMID:20960543) RGD PMID:20960543 MGI:4847981 NCBI chr 2:174,681,676...174,689,061
Ensembl chr 2:174,681,682...174,690,866 		JBrowse link
G Eln elastin involved_in IEA
ISO		 GO_REF:0000107
(MGI:5142190|PMID:20576933)		 Ensembl
RGD		 PMID:20576933 GO_REF:0000107 MGI:5142190 NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928 		JBrowse link
G Emilin1 elastin microfibril interfacer 1 involved_in ISO (MGI:5605894|PMID:25056700) RGD PMID:25056700 MGI:5605894 NCBI chr 6:25,455,974...25,463,713
Ensembl chr 6:25,445,298...25,463,698 		JBrowse link
G Gata3 GATA binding protein 3 involved_in ISO (MGI:3832106|PMID:18955134) RGD PMID:18955134 MGI:3832106 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391 		JBrowse link
G Gata4 GATA binding protein 4 involved_in ISO (PMID:29325903) RGD PMID:29325903 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636 		JBrowse link
G Gata5 GATA binding protein 5 involved_in ISO (PMID:22641149), (PMID:24638895)
(MGI:5286818|PMID:21633169)		 RGD PMID:21633169 PMID:22641149 PMID:24638895 MGI:5286818 NCBI chr 3:167,418,563...167,426,751
Ensembl chr 3:167,418,565...167,426,751 		JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 involved_in ISO (MGI:6158746|PMID:22110751) RGD PMID:22110751 MGI:6158746 NCBI chr 2:93,096,605...93,100,316
Ensembl chr 2:93,095,498...93,100,312 		JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 involved_in ISO (MGI:6158746|PMID:22110751) RGD PMID:22110751 MGI:6158746 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218 		JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 acts_upstream_of_or_within ISO MGI:2181762 (PMID:9515964) RGD PMID:9515964 NCBI chr18:74,046,422...74,156,041
Ensembl chr18:74,046,904...74,156,028 		JBrowse link
G Nos3 nitric oxide synthase 3 involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:Q01705 (MGI:3609262|PMID:10821808), (MGI:6158784|PMID:27107132), (MGI:6158885|PMID:23583836)		 Ensembl
RGD		 PMID:10821808 PMID:23583836 PMID:27107132 GO_REF:0000107 MGI:3609262 MGI:6158784 MGI:6158885 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO (PMID:16025100), (PMID:17662764), (PMID:18593716)
UniProtKB:P70313 (MGI:6158728|PMID:26491108), (MGI:6158784|PMID:27107132), (MGI:6158885|PMID:23583836)		 RGD PMID:16025100 PMID:17662764 PMID:18593716 PMID:23583836 PMID:26491108 More... MGI:6158728 MGI:6158784 MGI:6158885 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Rb1 RB transcriptional corepressor 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:6112863|PMID:29304157)		 Ensembl
RGD		 PMID:29304157 GO_REF:0000107 MGI:6112863 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302 		JBrowse link
G Robo1 roundabout guidance receptor 1 involved_in ISO UniProtKB:Q7TPD3 (MGI:5913048|PMID:25691540) RGD PMID:25691540 MGI:5913048 NCBI chr11:10,580,863...11,621,675
Ensembl chr11:10,580,908...11,620,203 		JBrowse link
G Robo2 roundabout guidance receptor 2 involved_in ISO UniProtKB:O89026 (MGI:5913048|PMID:25691540) RGD PMID:25691540 MGI:5913048 NCBI chr11:12,528,949...14,096,726
Ensembl chr11:12,528,951...13,041,536 		JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 involved_in ISO UniProtKB:M3TYT0 (PMID:26634652) RGD PMID:26634652 NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571 		JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in ISO UniProtKB:I3LFH3 (PMID:26634652) RGD PMID:26634652 NCBI chr 6:39,679,116...39,774,033
Ensembl chr 6:39,679,082...39,774,031 		JBrowse link
G Slit2 slit guidance ligand 2 involved_in ISO (MGI:5913048|PMID:25691540) RGD PMID:25691540 MGI:5913048 NCBI chr14:62,616,337...62,955,934
Ensembl chr14:62,617,067...62,955,948 		JBrowse link
G Slit3 slit guidance ligand 3 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5913048|PMID:25691540)		 Ensembl
RGD		 PMID:25691540 GO_REF:0000107 MGI:5913048 NCBI chr10:19,571,798...20,156,634
Ensembl chr10:19,571,684...20,156,634 		JBrowse link
G Smad2 SMAD family member 2 involved_in ISO UniProtKB:Q9R001 (MGI:5693221|PMID:23531444) RGD PMID:23531444 MGI:5693221 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323 		JBrowse link
G Smad6 SMAD family member 6 involved_in ISO (PMID:22275001) RGD PMID:22275001 NCBI chr 8:64,450,114...64,519,673
Ensembl chr 8:64,450,114...64,519,763 		JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in ISO (PMID:22110751) RGD PMID:22110751 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
G Tbx20 T-box transcription factor 20 involved_in ISO (PMID:18275040), (PMID:18834961) RGD PMID:18275040 PMID:18834961 NCBI chr 8:23,200,104...23,258,218
Ensembl chr 8:23,204,507...23,258,175 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO (PMID:26634652)
(MGI:5921830|PMID:26634652)		 RGD PMID:26634652 MGI:5921830 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 involved_in ISO
IEA		 (PMID:20101701)
GO_REF:0000107		 RGD
Ensembl		 PMID:20101701 GO_REF:0000107 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228 		JBrowse link
G Tie1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 involved_in ISO (MGI:6370101|PMID:31319059) RGD PMID:31319059 MGI:6370101 NCBI chr 5:132,000,013...132,019,658
Ensembl chr 5:132,000,015...132,019,592 		JBrowse link
G Twist1 twist family bHLH transcription factor 1 involved_in ISO (PMID:20804746)
(MGI:4838344|PMID:20804746)		 RGD PMID:20804746 MGI:4838344 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653 		JBrowse link
pulmonary valve development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO GO:1905314 (MGI:2429424|PMID:12441304) RGD PMID:12441304 MGI:2429424 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809 		JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 involved_in ISO (MGI:5319103|PMID:22300732) RGD PMID:22300732 MGI:5319103 NCBI chr18:74,046,422...74,156,041
Ensembl chr18:74,046,904...74,156,028 		JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region involved_in ISO (MGI:6158728|PMID:26491108) RGD PMID:26491108 MGI:6158728 NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A involved_in ISO UniProtKB:P25119 (MGI:6158728|PMID:26491108) RGD PMID:26491108 MGI:6158728 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B involved_in ISO UniProtKB:P25118 (MGI:6158728|PMID:26491108) RGD PMID:26491108 MGI:6158728 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206 		JBrowse link
pulmonary valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gja5 gap junction protein, alpha 5 involved_in ISO (PMID:22199024) RGD PMID:22199024 NCBI chr 2:184,602,407...184,621,952
Ensembl chr 2:184,564,475...184,621,952 		JBrowse link
G Tbx20 T-box transcription factor 20 involved_in ISO (MGI:3604925|PMID:15843409) RGD PMID:15843409 MGI:3604925 NCBI chr 8:23,200,104...23,258,218
Ensembl chr 8:23,204,507...23,258,175 		JBrowse link
pulmonary valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts19 ADAM metallopeptidase with thrombospondin type 1 motif, 19 involved_in ISO (PMID:32323311) RGD PMID:32323311 NCBI chr18:52,346,448...52,531,245
Ensembl chr18:52,347,428...52,530,509 		JBrowse link
G Adamts5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 involved_in ISO (MGI:5693221|PMID:23531444) RGD PMID:23531444 MGI:5693221 NCBI chr11:25,000,627...25,047,205
Ensembl chr11:25,000,637...25,047,205 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in IEA
ISO		 GO_REF:0000107
(MGI:3039210|PMID:15070745), (MGI:3814273|PMID:18924235)		 Ensembl
RGD		 PMID:15070745 PMID:18924235 GO_REF:0000107 MGI:3039210 MGI:3814273 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 involved_in ISO UniProtKB:Q9DBX7 (MGI:3783952|PMID:17303760) RGD PMID:17303760 MGI:3783952 NCBI chr 2:93,096,605...93,100,316
Ensembl chr 2:93,095,498...93,100,312 		JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 involved_in ISO (MGI:2386835|PMID:12372254) RGD PMID:12372254 MGI:2386835 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218 		JBrowse link
G Heyl hes-related family bHLH transcription factor with YRPW motif-like involved_in ISO UniProtKB:Q9WV93 (MGI:3783952|PMID:17303760) RGD PMID:17303760 MGI:3783952 NCBI chr 5:135,508,160...135,525,152
Ensembl chr 5:135,508,160...135,525,152 		JBrowse link
G Jag1 jagged canonical Notch ligand 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:20437614), (PMID:9207787)		 Ensembl
RGD		 PMID:9207787 PMID:20437614 GO_REF:0000107 NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209 		JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 acts_upstream_of_or_within ISO MGI:2181762 (PMID:9515964) RGD PMID:9515964 NCBI chr18:74,046,422...74,156,041
Ensembl chr18:74,046,904...74,156,028 		JBrowse link
G Nos3 nitric oxide synthase 3 involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:Q01705 (MGI:6158784|PMID:27107132)		 Ensembl
RGD		 PMID:27107132 GO_REF:0000107 MGI:6158784 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO (PMID:16025100)
UniProtKB:P70313 (MGI:6158728|PMID:26491108), (MGI:6158784|PMID:27107132)		 RGD PMID:16025100 PMID:26491108 PMID:27107132 MGI:6158728 MGI:6158784 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Notch2 notch receptor 2 involved_in ISO
IEA		 (PMID:16773578)
GO_REF:0000107		 RGD
Ensembl		 PMID:16773578 GO_REF:0000107 NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088 		JBrowse link
G Robo1 roundabout guidance receptor 1 involved_in ISO UniProtKB:Q7TPD3 (MGI:5913048|PMID:25691540) RGD PMID:25691540 MGI:5913048 NCBI chr11:10,580,863...11,621,675
Ensembl chr11:10,580,908...11,620,203 		JBrowse link
G Robo2 roundabout guidance receptor 2 involved_in ISO UniProtKB:O89026 (MGI:5913048|PMID:25691540) RGD PMID:25691540 MGI:5913048 NCBI chr11:12,528,949...14,096,726
Ensembl chr11:12,528,951...13,041,536 		JBrowse link
G Slit2 slit guidance ligand 2 involved_in ISO (MGI:5913048|PMID:25691540) RGD PMID:25691540 MGI:5913048 NCBI chr14:62,616,337...62,955,934
Ensembl chr14:62,617,067...62,955,948 		JBrowse link
G Smad2 SMAD family member 2 involved_in ISO UniProtKB:Q9R001 (MGI:5693221|PMID:23531444) RGD PMID:23531444 MGI:5693221 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323 		JBrowse link
G Smad6 SMAD family member 6 involved_in ISO (MGI:1352979|PMID:10655064) RGD PMID:10655064 MGI:1352979 NCBI chr 8:64,450,114...64,519,673
Ensembl chr 8:64,450,114...64,519,763 		JBrowse link
G Stra6 signaling receptor and transporter of retinol STRA6 involved_in ISO
IEA		 (PMID:17273977)
GO_REF:0000107		 RGD
Ensembl		 PMID:17273977 GO_REF:0000107 NCBI chr 8:58,548,899...58,568,861
Ensembl chr 8:58,549,736...58,568,860 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISO (MGI:894212|PMID:9217007) RGD PMID:9217007 MGI:894212 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    developmental process 7068
      anatomical structure development 6575
        heart valve development 69
          semi-lunar valve development 44
            aortic valve development + 38
            pulmonary valve development + 24
Path 2
Term Annotations click to browse term
  biological_process 20413
    developmental process 7068
      anatomical structure development 6575
        multicellular organism development 5290
          system development 4576
            circulatory system development 1378
              heart development 747
                heart valve development 69
                  semi-lunar valve development 44
                    aortic valve development + 38
                    pulmonary valve development + 24
paths to the root