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ONTOLOGY REPORT - ANNOTATIONS

Term:cellular response to acetylcholine
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Accession:GO:1905145 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus.


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cellular response to acetylcholine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3703409|PMID:16956963)		 UniProt
RGD		 PMID:16956963 GO_REF:0000024 MGI:3703409 NCBI chr13:45,156,137...45,255,292
Ensembl chr13:45,156,146...45,255,246 		JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in ISO (MGI:6271078|PMID:29353861) RGD PMID:29353861 MGI:6271078 NCBI chr 6:39,679,116...39,774,033
Ensembl chr 6:39,679,082...39,774,031 		JBrowse link
acetylcholine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2179948 (MGI:3609472|PMID:14645660)		 Ensembl
RGD		 PMID:14645660 GO_REF:0000107 MGI:3609472 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 involved_in ISO (PMID:17478539) RGD PMID:17478539 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278 		JBrowse link
G Chrna1 cholinergic receptor nicotinic alpha 1 subunit involved_in ISO
NAS		 (MGI:6850201|PMID:15864502)
GO_REF:0000114
PMID:21480901		 RGD
ComplexPortal		 PMID:15864502 PMID:21480901 GO_REF:0000114 MGI:6850201, RGD:151356629 NCBI chr 3:58,454,763...58,469,832
Ensembl chr 3:58,454,744...58,469,840 		JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit involved_in IGI PMID:21540349 ARUK-UCL PMID:21540349 RGD:12790638 NCBI chr 8:55,401,981...55,415,012
Ensembl chr 8:55,401,702...55,415,165 		JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit acts_upstream_of_or_within ISO (MGI:5694852|PMID:26276394) RGD PMID:26276394 MGI:5694852 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit involved_in IDA PMID:21540349 ARUK-UCL PMID:21540349 RGD:12790638 NCBI chr 1:116,715,286...116,837,223
Ensembl chr 1:116,714,711...116,837,240 		JBrowse link
G Chrnb1 cholinergic receptor nicotinic beta 1 subunit involved_in ISO
NAS		 (MGI:6850201|PMID:15864502)
PMID:21480901
GO_REF:0000114		 RGD
ComplexPortal		 PMID:15864502 PMID:21480901 GO_REF:0000114 MGI:6850201, RGD:151356629 NCBI chr10:54,501,096...54,516,418
Ensembl chr10:54,501,093...54,516,345 		JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit involved_in
acts_upstream_of_or_within		 IGI
ISO		 PMID:21540349
(MGI:5694852|PMID:26276394)		 RGD PMID:26276394 PMID:21540349 MGI:5694852, RGD:12790638 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619 		JBrowse link
G Chrnd cholinergic receptor nicotinic delta subunit involved_in ISO
NAS		 (MGI:6850201|PMID:15864502)
GO_REF:0000114
PMID:21480901		 RGD
ComplexPortal		 PMID:15864502 PMID:21480901 GO_REF:0000114 MGI:6850201, RGD:151356629 NCBI chr 9:87,862,417...87,870,833
Ensembl chr 9:87,862,407...87,870,833 		JBrowse link
G Chrne cholinergic receptor nicotinic epsilon subunit involved_in ISO (MGI:6850201|PMID:15864502)
GO_REF:0000114		 RGD
ComplexPortal		 PMID:15864502 GO_REF:0000114 MGI:6850201 NCBI chr10:55,331,211...55,339,923
Ensembl chr10:55,331,212...55,335,530 		JBrowse link
G Chrng cholinergic receptor nicotinic gamma subunit involved_in NAS PMID:21480901 ComplexPortal PMID:21480901 RGD:151356629 NCBI chr 9:87,878,085...87,884,193
Ensembl chr 9:87,878,085...87,914,482 		JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein acts_upstream_of_or_within ISO MGI:1924574|MGI:700014 (MGI:5803938|PMID:26527617) RGD PMID:26527617 MGI:5803938 NCBI chr11:83,528,788...83,563,214
Ensembl chr11:83,526,530...83,563,238 		JBrowse link
G Large1 LARGE xylosyl- and glucuronyltransferase 1 acts_upstream_of_or_within ISO MGI:1856965 (MGI:4430057|PMID:19346129) RGD PMID:19346129 MGI:4430057 NCBI chr19:11,603,129...12,048,930
Ensembl chr19:11,603,129...12,048,930 		JBrowse link
G Ly6c Ly6-C antigen involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:106,959,508...106,963,360
Ensembl chr 7:106,959,511...106,963,329 		JBrowse link
G Ly6e lymphocyte antigen 6 family member E acts_upstream_of_or_within ISO (MGI:5694852|PMID:26276394) RGD PMID:26276394 MGI:5694852 NCBI chr 7:106,935,530...106,939,689
Ensembl chr 7:106,935,761...106,939,689 		JBrowse link
G Ly6g6d lymphocyte antigen 6 family member G6D involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:5694852|PMID:26276394)		 RGD PMID:26276394 PMID:21873635 MGI:5694852, RGD:13792537 NCBI chr20:3,749,598...3,752,181
Ensembl chr20:3,737,459...3,752,248 		JBrowse link
G Ly6g6e lymphocyte antigen 6 family member G6E acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:5694852|PMID:26276394)
PMID:21873635		 RGD PMID:26276394 PMID:21873635 MGI:5694852, RGD:13792537 NCBI chr20:3,744,999...3,749,867
Ensembl chr20:3,744,999...3,750,849 		JBrowse link
G Ly6h lymphocyte antigen 6 family member H involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:5694852|PMID:26276394)		 RGD PMID:26276394 PMID:21873635 MGI:5694852, RGD:13792537 NCBI chr 7:107,258,779...107,261,270
Ensembl chr 7:107,258,779...107,261,454 		JBrowse link
G Ly6i lymphocyte antigen 6 complex, locus I involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:107,062,320...107,067,743
Ensembl chr 7:107,062,325...107,067,310 		JBrowse link
G Lypd1 Ly6/Plaur domain containing 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:5694852|PMID:26276394)		 RGD PMID:26276394 PMID:21873635 MGI:5694852, RGD:13792537 NCBI chr13:37,326,459...37,368,515
Ensembl chr13:37,326,464...37,368,493 		JBrowse link
G RGD1565410 similar to Ly6-C antigen gene involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:107,122,197...107,163,755
Ensembl chr 7:107,011,588...107,163,788 		JBrowse link
G Slurp2 secreted Ly6/Plaur domain containing 2 involved_in ISO (PMID:27485575) RGD PMID:27485575 NCBI chr 7:106,627,775...106,631,655
Ensembl chr 7:106,627,775...106,631,655 		JBrowse link
G Sorbs1 sorbin and SH3 domain containing 1 acts_upstream_of_or_within ISO MGI:104686|MGI:1924574 (MGI:5803938|PMID:26527617) RGD PMID:26527617 MGI:5803938 NCBI chr 1:239,107,882...239,330,276
Ensembl chr 1:239,108,777...239,330,169 		JBrowse link
G Sorbs2 sorbin and SH3 domain containing 2 acts_upstream_of_or_within ISO MGI:104686|MGI:700014 (MGI:5803938|PMID:26527617) RGD PMID:26527617 MGI:5803938 NCBI chr16:46,435,220...46,748,743
Ensembl chr16:46,435,237...46,626,514 		JBrowse link
adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrm1 cholinergic receptor, muscarinic 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:205,567,046...205,583,001
Ensembl chr 1:205,567,220...205,582,356 		JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278 		JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 involved_in
acts_upstream_of_or_within		 IBA
ISO
IEA		 PMID:21873635
(MGI:61071|PMID:7916637)
GO_REF:0000107		 RGD
Ensembl		 PMID:7916637 PMID:21873635 GO_REF:0000107 MGI:61071, RGD:13792537 NCBI chr 3:77,893,425...77,901,166
Ensembl chr 3:77,893,425...77,901,159 		JBrowse link
G Chrm5 cholinergic receptor, muscarinic 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:99,284,846...99,337,252
Ensembl chr 3:99,284,846...99,337,252 		JBrowse link
G Hrh3 histamine receptor H3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:167,191,551...167,196,642
Ensembl chr 3:167,191,558...167,196,642 		JBrowse link
G Hrh4 histamine receptor H4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:4,166,270...4,182,426
Ensembl chr18:4,166,270...4,246,345 		JBrowse link
G Oprm1 opioid receptor, mu 1 involved_in IDA PMID:8051154 GO_Central PMID:8051154 RGD:8656009 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
G protein-coupled acetylcholine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agrn agrin involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:166,749,306...166,782,212
Ensembl chr 5:166,749,310...166,786,003 		JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 involved_in IDA PMID:11276227 UniProt PMID:11276227 RGD:8554712 NCBI chr10:65,484,266...65,485,467
Ensembl chr10:65,483,941...65,488,456 		JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 involved_in IDA
ISO		 (PMID:12196552) RGD PMID:12196552 PMID:12534975 RGD:724727 NCBI chr 1:205,567,046...205,583,001
Ensembl chr 1:205,567,220...205,582,356 		JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 acts_upstream_of_or_within
involved_in		 IDA
ISO		 MGI:2155543 (MGI:1331246|PMID:9990086)
(PMID:24256733)		 RGD PMID:9990086 PMID:24256733 PMID:12534975 MGI:1331246, RGD:724727 NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 involved_in IDA
IMP		 PMID:1527051 RGD
UniProt		 PMID:12185001 PMID:1527051 PMID:15141107 RGD:724728, RGD:10047264, RGD:2303392 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278 		JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 acts_upstream_of_or_within ISO (MGI:61071|PMID:7916637) RGD PMID:7916637 MGI:61071 NCBI chr 3:77,893,425...77,901,166
Ensembl chr 3:77,893,425...77,901,159 		JBrowse link
G Gnai2 G protein subunit alpha i2 acts_upstream_of_or_within ISO MGI:2152603 (MGI:1934424|PMID:11299198) RGD PMID:11299198 MGI:1934424 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979 		JBrowse link
G Plcb1 phospholipase C beta 1 involved_in ISO (MGI:1097045|PMID:9305844) RGD PMID:9305844 MGI:1097045 NCBI chr 3:122,059,968...122,772,896
Ensembl chr 3:122,060,031...122,772,869 		JBrowse link
G Rgs10 regulator of G-protein signaling 10 involved_in ISS
ISO		 GO_REF:0000024
(PMID:11443111)		 UniProt
RGD		 PMID:11443111 GO_REF:0000024 NCBI chr 1:182,946,334...182,987,729
Ensembl chr 1:182,946,336...182,987,697 		JBrowse link
G Rgs8 regulator of G-protein signaling 8 involved_in IDA PMID:9394004 UniProt PMID:9394004 RGD:69963 NCBI chr13:65,804,703...65,848,953
Ensembl chr13:65,804,797...65,846,807 		JBrowse link
phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa7 annexin A7 acts_upstream_of_or_within_positive_effect ISO MGI:2159005 (MGI:1349234|PMID:10570150) RGD PMID:10570150 MGI:1349234 NCBI chr15:3,821,798...3,849,659
Ensembl chr15:3,821,845...3,849,385 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 involved_in ISO MGI:3770175 (MGI:3769934|PMID:16753580), (MGI:4459350|PMID:20440069) RGD PMID:16753580 PMID:20440069 MGI:3769934 MGI:4459350 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278 		JBrowse link
G Gna11 G protein subunit alpha 11 involved_in ISO
IEA		 MGI:95766|MGI:95776 (MGI:4459350|PMID:20440069)
GO_REF:0000107		 RGD
Ensembl		 PMID:20440069 GO_REF:0000107 MGI:4459350 NCBI chr 7:8,163,752...8,177,636
Ensembl chr 7:8,162,750...8,179,812 		JBrowse link
G Gnaq G protein subunit alpha q involved_in ISO
IEA		 MGI:95766|MGI:95776 (MGI:4459350|PMID:20440069)
GO_REF:0000107		 RGD
Ensembl		 PMID:20440069 GO_REF:0000107 MGI:4459350 NCBI chr 1:213,425,631...213,671,947
Ensembl chr 1:213,424,465...213,667,672 		JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 involved_in ISO MGI:88031 (MGI:1349234|PMID:10570150) RGD PMID:10570150 MGI:1349234 NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491 		JBrowse link
G Plcb1 phospholipase C beta 1 involved_in ISO
IEA		 MGI:6460327|MGI:88031 (MGI:1349234|PMID:10570150), (MGI:6435050|PMID:31268747)
GO_REF:0000107		 RGD
Ensembl		 PMID:10570150 PMID:31268747 GO_REF:0000107 MGI:1349234 MGI:6435050 NCBI chr 3:122,059,968...122,772,896
Ensembl chr 3:122,060,031...122,772,869 		JBrowse link
G Prkcb protein kinase C, beta involved_in ISO
IEA		 (MGI:7335149|PMID:27226533)
GO_REF:0000107		 RGD
Ensembl		 PMID:27226533 GO_REF:0000107 MGI:7335149 NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536 		JBrowse link
G Stim1 stromal interaction molecule 1 involved_in ISO (MGI:7335147|PMID:18452988) RGD PMID:18452988 MGI:7335147 NCBI chr 1:156,656,246...156,818,777
Ensembl chr 1:156,656,013...156,818,363 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19738
    response to stimulus 10453
      response to chemical 6038
        cellular response to chemical stimulus 3216
          cellular response to oxygen-containing compound 1738
            cellular response to acetylcholine 45
              acetylcholine receptor signaling pathway + 43
              acetylcholine-induced gastric acid secretion 0
Path 2
Term Annotations click to browse term
  biological_process 19738
    response to stimulus 10453
      cellular response to stimulus 8820
        cellular response to chemical stimulus 3216
          cellular response to nitrogen compound 959
            cellular response to organonitrogen compound 912
              cellular response to acetylcholine 45
                acetylcholine receptor signaling pathway + 43
                acetylcholine-induced gastric acid secretion 0
paths to the root