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ONTOLOGY REPORT - ANNOTATIONS

Term:response to acetylcholine
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Accession:GO:1905144 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus.


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response to acetylcholine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrm3 cholinergic receptor, muscarinic 3 involved_in IMP 4-DAMP methiodide CHEBI:73340
hexahydrosiladifenidol		 RGD PMID:8075871 PMID:9316844 RGD:2303390, RGD:2303391 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278 		JBrowse link
G Chrna2 cholinergic receptor nicotinic alpha 2 subunit IDA RGD PMID:15016836 RGD:2303194 NCBI chr15:40,342,317...40,358,601
Ensembl chr15:40,342,317...40,358,601 		JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit involved_in IGI PMID:21540349 ARUK-UCL PMID:21540349 RGD:12790638 NCBI chr 8:55,401,981...55,415,012
Ensembl chr 8:55,401,702...55,415,165 		JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit IDA RGD PMID:15016836 RGD:2303194 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit involved_in IDA
ISO		 PMID:17898229
ivermectin (CHEBI:6078)
(PMID:17898229)
PMID:21540349		 RGD PMID:17898229 PMID:17898229 PMID:16282518 PMID:21540349 RGD:12050111, RGD:1642691, RGD:12790638 NCBI chr 1:116,715,286...116,837,223
Ensembl chr 1:116,714,711...116,837,240 		JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit involved_in IGI
IDA		 PMID:21540349 ARUK-UCL
RGD		 PMID:21540349 PMID:15016836 RGD:12790638, RGD:2303194 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619 		JBrowse link
G Ednra endothelin receptor type A involved_in ISO (MGI:6107503|PMID:26531127) RGD PMID:26531127 MGI:6107503 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049 		JBrowse link
G Tspo translocator protein IMP RGD PMID:29074640 RGD:150429771 NCBI chr 7:114,720,188...114,730,450
Ensembl chr 7:114,720,188...114,730,450 		JBrowse link
acetylcholine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2179948 (MGI:3609472|PMID:14645660)		 Ensembl
RGD		 PMID:14645660 GO_REF:0000107 MGI:3609472 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 involved_in ISO (PMID:17478539) RGD PMID:17478539 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278 		JBrowse link
G Chrna1 cholinergic receptor nicotinic alpha 1 subunit involved_in ISO
NAS		 (MGI:6850201|PMID:15864502)
GO_REF:0000114
PMID:21480901		 RGD
ComplexPortal		 PMID:15864502 PMID:21480901 GO_REF:0000114 MGI:6850201, RGD:151356629 NCBI chr 3:58,454,763...58,469,832
Ensembl chr 3:58,454,744...58,469,840 		JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit involved_in IGI PMID:21540349 ARUK-UCL PMID:21540349 RGD:12790638 NCBI chr 8:55,401,981...55,415,012
Ensembl chr 8:55,401,702...55,415,165 		JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit acts_upstream_of_or_within ISO (MGI:5694852|PMID:26276394) RGD PMID:26276394 MGI:5694852 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit involved_in IDA PMID:21540349 ARUK-UCL PMID:21540349 RGD:12790638 NCBI chr 1:116,715,286...116,837,223
Ensembl chr 1:116,714,711...116,837,240 		JBrowse link
G Chrnb1 cholinergic receptor nicotinic beta 1 subunit involved_in ISO
NAS		 (MGI:6850201|PMID:15864502)
GO_REF:0000114
PMID:21480901		 RGD
ComplexPortal		 PMID:15864502 PMID:21480901 GO_REF:0000114 MGI:6850201, RGD:151356629 NCBI chr10:54,501,096...54,516,418
Ensembl chr10:54,501,093...54,516,345 		JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit involved_in
acts_upstream_of_or_within		 IGI
ISO		 PMID:21540349
(MGI:5694852|PMID:26276394)		 RGD PMID:26276394 PMID:21540349 MGI:5694852, RGD:12790638 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619 		JBrowse link
G Chrnd cholinergic receptor nicotinic delta subunit involved_in ISO
NAS		 (MGI:6850201|PMID:15864502)
PMID:21480901
GO_REF:0000114		 RGD
ComplexPortal		 PMID:15864502 PMID:21480901 GO_REF:0000114 MGI:6850201, RGD:151356629 NCBI chr 9:87,862,417...87,870,833
Ensembl chr 9:87,862,407...87,870,833 		JBrowse link
G Chrne cholinergic receptor nicotinic epsilon subunit involved_in ISO (MGI:6850201|PMID:15864502)
GO_REF:0000114		 RGD
ComplexPortal		 PMID:15864502 GO_REF:0000114 MGI:6850201 NCBI chr10:55,331,211...55,339,923
Ensembl chr10:55,331,212...55,335,530 		JBrowse link
G Chrng cholinergic receptor nicotinic gamma subunit involved_in NAS PMID:21480901 ComplexPortal PMID:21480901 RGD:151356629 NCBI chr 9:87,878,085...87,884,193
Ensembl chr 9:87,878,085...87,914,482 		JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein acts_upstream_of_or_within ISO MGI:1924574|MGI:700014 (MGI:5803938|PMID:26527617) RGD PMID:26527617 MGI:5803938 NCBI chr11:83,528,788...83,563,214
Ensembl chr11:83,526,530...83,563,238 		JBrowse link
G Large1 LARGE xylosyl- and glucuronyltransferase 1 acts_upstream_of_or_within ISO MGI:1856965 (MGI:4430057|PMID:19346129) RGD PMID:19346129 MGI:4430057 NCBI chr19:11,603,129...12,048,930
Ensembl chr19:11,603,129...12,048,930 		JBrowse link
G Ly6c Ly6-C antigen involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:106,959,508...106,963,360
Ensembl chr 7:106,959,511...106,963,329 		JBrowse link
G Ly6e lymphocyte antigen 6 family member E acts_upstream_of_or_within ISO (MGI:5694852|PMID:26276394) RGD PMID:26276394 MGI:5694852 NCBI chr 7:106,935,530...106,939,689
Ensembl chr 7:106,935,761...106,939,689 		JBrowse link
G Ly6g6d lymphocyte antigen 6 family member G6D involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:5694852|PMID:26276394)		 RGD PMID:26276394 PMID:21873635 MGI:5694852, RGD:13792537 NCBI chr20:3,749,598...3,752,181
Ensembl chr20:3,737,459...3,752,248 		JBrowse link
G Ly6g6e lymphocyte antigen 6 family member G6E acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:5694852|PMID:26276394)
PMID:21873635		 RGD PMID:26276394 PMID:21873635 MGI:5694852, RGD:13792537 NCBI chr20:3,744,999...3,749,867
Ensembl chr20:3,744,999...3,750,849 		JBrowse link
G Ly6h lymphocyte antigen 6 family member H involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:5694852|PMID:26276394)		 RGD PMID:26276394 PMID:21873635 MGI:5694852, RGD:13792537 NCBI chr 7:107,258,779...107,261,270
Ensembl chr 7:107,258,779...107,261,454 		JBrowse link
G Ly6i lymphocyte antigen 6 complex, locus I involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:107,062,320...107,067,743
Ensembl chr 7:107,062,325...107,067,310 		JBrowse link
G Lypd1 Ly6/Plaur domain containing 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:5694852|PMID:26276394)		 RGD PMID:26276394 PMID:21873635 MGI:5694852, RGD:13792537 NCBI chr13:37,326,459...37,368,515
Ensembl chr13:37,326,464...37,368,493 		JBrowse link
G RGD1565410 similar to Ly6-C antigen gene involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:107,122,197...107,163,755
Ensembl chr 7:107,011,588...107,163,788 		JBrowse link
G Slurp2 secreted Ly6/Plaur domain containing 2 involved_in ISO (PMID:27485575) RGD PMID:27485575 NCBI chr 7:106,627,775...106,631,655
Ensembl chr 7:106,627,775...106,631,655 		JBrowse link
G Sorbs1 sorbin and SH3 domain containing 1 acts_upstream_of_or_within ISO MGI:104686|MGI:1924574 (MGI:5803938|PMID:26527617) RGD PMID:26527617 MGI:5803938 NCBI chr 1:239,107,882...239,330,276
Ensembl chr 1:239,108,777...239,330,169 		JBrowse link
G Sorbs2 sorbin and SH3 domain containing 2 acts_upstream_of_or_within ISO MGI:104686|MGI:700014 (MGI:5803938|PMID:26527617) RGD PMID:26527617 MGI:5803938 NCBI chr16:46,435,220...46,748,743
Ensembl chr16:46,435,237...46,626,514 		JBrowse link
adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrm1 cholinergic receptor, muscarinic 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:205,567,046...205,583,001
Ensembl chr 1:205,567,220...205,582,356 		JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278 		JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 involved_in
acts_upstream_of_or_within		 IBA
ISO
IEA		 PMID:21873635
(MGI:61071|PMID:7916637)
GO_REF:0000107		 RGD
Ensembl		 PMID:7916637 PMID:21873635 GO_REF:0000107 MGI:61071, RGD:13792537 NCBI chr 3:77,893,425...77,901,166
Ensembl chr 3:77,893,425...77,901,159 		JBrowse link
G Chrm5 cholinergic receptor, muscarinic 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:99,284,846...99,337,252
Ensembl chr 3:99,284,846...99,337,252 		JBrowse link
G Hrh3 histamine receptor H3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:167,191,551...167,196,642
Ensembl chr 3:167,191,558...167,196,642 		JBrowse link
G Hrh4 histamine receptor H4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:4,166,270...4,182,426
Ensembl chr18:4,166,270...4,246,345 		JBrowse link
G Oprm1 opioid receptor, mu 1 involved_in IDA PMID:8051154 GO_Central PMID:8051154 RGD:8656009 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
cellular response to acetylcholine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3703409|PMID:16956963)		 UniProt
RGD		 PMID:16956963 GO_REF:0000024 MGI:3703409 NCBI chr13:45,156,137...45,255,292
Ensembl chr13:45,156,146...45,255,246 		JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in ISO (MGI:6271078|PMID:29353861) RGD PMID:29353861 MGI:6271078 NCBI chr 6:39,679,116...39,774,033
Ensembl chr 6:39,679,082...39,774,031 		JBrowse link
G protein-coupled acetylcholine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agrn agrin involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:166,749,306...166,782,212
Ensembl chr 5:166,749,310...166,786,003 		JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 involved_in IDA PMID:11276227 UniProt PMID:11276227 RGD:8554712 NCBI chr10:65,484,266...65,485,467
Ensembl chr10:65,483,941...65,488,456 		JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 involved_in IDA
ISO		 (PMID:12196552) RGD PMID:12196552 PMID:12534975 RGD:724727 NCBI chr 1:205,567,046...205,583,001
Ensembl chr 1:205,567,220...205,582,356 		JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 acts_upstream_of_or_within
involved_in		 IDA
ISO		 MGI:2155543 (MGI:1331246|PMID:9990086)
(PMID:24256733)		 RGD PMID:9990086 PMID:24256733 PMID:12534975 MGI:1331246, RGD:724727 NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 involved_in IDA
IMP		 PMID:1527051 RGD
UniProt		 PMID:12185001 PMID:1527051 PMID:15141107 RGD:724728, RGD:10047264, RGD:2303392 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278 		JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 acts_upstream_of_or_within ISO (MGI:61071|PMID:7916637) RGD PMID:7916637 MGI:61071 NCBI chr 3:77,893,425...77,901,166
Ensembl chr 3:77,893,425...77,901,159 		JBrowse link
G Gnai2 G protein subunit alpha i2 acts_upstream_of_or_within ISO MGI:2152603 (MGI:1934424|PMID:11299198) RGD PMID:11299198 MGI:1934424 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979 		JBrowse link
G Plcb1 phospholipase C beta 1 involved_in ISO (MGI:1097045|PMID:9305844) RGD PMID:9305844 MGI:1097045 NCBI chr 3:122,059,968...122,772,896
Ensembl chr 3:122,060,031...122,772,869 		JBrowse link
G Rgs10 regulator of G-protein signaling 10 involved_in ISS
ISO		 GO_REF:0000024
(PMID:11443111)		 UniProt
RGD		 PMID:11443111 GO_REF:0000024 NCBI chr 1:182,946,334...182,987,729
Ensembl chr 1:182,946,336...182,987,697 		JBrowse link
G Rgs8 regulator of G-protein signaling 8 involved_in IDA PMID:9394004 UniProt PMID:9394004 RGD:69963 NCBI chr13:65,804,703...65,848,953
Ensembl chr13:65,804,797...65,846,807 		JBrowse link
phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa7 annexin A7 acts_upstream_of_or_within_positive_effect ISO MGI:2159005 (MGI:1349234|PMID:10570150) RGD PMID:10570150 MGI:1349234 NCBI chr15:3,821,798...3,849,659
Ensembl chr15:3,821,845...3,849,385 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 involved_in ISO MGI:3770175 (MGI:3769934|PMID:16753580), (MGI:4459350|PMID:20440069) RGD PMID:16753580 PMID:20440069 MGI:3769934 MGI:4459350 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278 		JBrowse link
G Gna11 G protein subunit alpha 11 involved_in ISO
IEA		 MGI:95766|MGI:95776 (MGI:4459350|PMID:20440069)
GO_REF:0000107		 RGD
Ensembl		 PMID:20440069 GO_REF:0000107 MGI:4459350 NCBI chr 7:8,163,752...8,177,636
Ensembl chr 7:8,162,750...8,179,812 		JBrowse link
G Gnaq G protein subunit alpha q involved_in ISO
IEA		 MGI:95766|MGI:95776 (MGI:4459350|PMID:20440069)
GO_REF:0000107		 RGD
Ensembl		 PMID:20440069 GO_REF:0000107 MGI:4459350 NCBI chr 1:213,425,631...213,671,947
Ensembl chr 1:213,424,465...213,667,672 		JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 involved_in ISO MGI:88031 (MGI:1349234|PMID:10570150) RGD PMID:10570150 MGI:1349234 NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491 		JBrowse link
G Plcb1 phospholipase C beta 1 involved_in ISO
IEA		 MGI:6460327|MGI:88031 (MGI:1349234|PMID:10570150), (MGI:6435050|PMID:31268747)
GO_REF:0000107		 RGD
Ensembl		 PMID:10570150 PMID:31268747 GO_REF:0000107 MGI:1349234 MGI:6435050 NCBI chr 3:122,059,968...122,772,896
Ensembl chr 3:122,060,031...122,772,869 		JBrowse link
G Prkcb protein kinase C, beta involved_in ISO
IEA		 (MGI:7335149|PMID:27226533)
GO_REF:0000107		 RGD
Ensembl		 PMID:27226533 GO_REF:0000107 MGI:7335149 NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536 		JBrowse link
G Stim1 stromal interaction molecule 1 involved_in ISO (MGI:7335147|PMID:18452988) RGD PMID:18452988 MGI:7335147 NCBI chr 1:156,656,246...156,818,777
Ensembl chr 1:156,656,013...156,818,363 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19738
    response to stimulus 10453
      response to chemical 6038
        response to oxygen-containing compound 2544
          response to acetylcholine 48
            cellular response to acetylcholine + 45
Path 2
Term Annotations click to browse term
  biological_process 19738
    response to stimulus 10453
      response to chemical 6038
        response to organic substance 3728
          response to organonitrogen compound 1514
            response to acetylcholine 48
              cellular response to acetylcholine + 45
paths to the root