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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of guanyl-nucleotide exchange factor activity
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Accession:GO:1905098 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of guanyl-nucleotide exchange factor activity.
Synonyms:exact_synonym: down regulation of GDP-dissociation stimulator activity;   down regulation of GDS;   down regulation of GEF;   down regulation of guanyl-nucleotide exchange factor activity;   down regulation of guanyl-nucleotide release factor activity;   down regulation of guanyl-nucleotide releasing factor;   downregulation of GDP-dissociation stimulator activity;   downregulation of GDS;   downregulation of GEF;   downregulation of guanyl-nucleotide exchange factor activity;   downregulation of guanyl-nucleotide release factor activity;   downregulation of guanyl-nucleotide releasing factor;   negative regulation of GDP-dissociation stimulator activity;   negative regulation of GDS;   negative regulation of GEF;   negative regulation of guanyl-nucleotide release factor activity;   negative regulation of guanyl-nucleotide releasing factor
 narrow_synonym: down regulation of GNRP;   downregulation of GNRP;   inhibition of GDP-dissociation stimulator activity;   inhibition of GDS;   inhibition of GEF;   inhibition of GNRP;   inhibition of guanyl-nucleotide exchange factor activity;   inhibition of guanyl-nucleotide release factor activity;   inhibition of guanyl-nucleotide releasing factor;   negative regulation of GNRP

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negative regulation of guanyl-nucleotide exchange factor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2b1 eukaryotic translation initiation factor 2B subunit alpha IDA RGD PMID:9582312 RGD:1581075 NCBI chr12:37,444,136...37,452,391
Ensembl chr12:37,444,072...37,465,398 		JBrowse link
G Eif2b4 eukaryotic translation initiation factor 2B subunit delta IDA RGD PMID:9582312 RGD:1581075 NCBI chr 6:26,546,917...26,552,474
Ensembl chr 6:26,546,924...26,552,430 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha IDA RGD PMID:9582312 RGD:1581075 NCBI chr 6:102,048,372...102,073,041
Ensembl chr 6:102,048,372...102,073,041 		JBrowse link
G Gpsm1 G-protein signaling modulator 1 involved_in ISO (PMID:11024022) RGD PMID:11024022 NCBI chr 3:3,767,394...3,794,360
Ensembl chr 3:3,767,394...3,794,359 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase involved_in IEA
ISO		 GO_REF:0000107
(PMID:25198505)		 Ensembl
RGD		 PMID:25198505 GO_REF:0000107 NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665 		JBrowse link
G Stmn1 stathmin 1 involved_in ISO (PMID:25198505) RGD PMID:25198505 NCBI chr 5:152,680,412...152,686,807
Ensembl chr 5:152,680,407...152,686,806 		JBrowse link
negative regulation of Rho guanyl-nucleotide exchange factor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ripor1 RHO family interacting cell polarization regulator 1 involved_in ISO (PMID:25588844) RGD PMID:25588844 NCBI chr19:37,555,940...37,584,842
Ensembl chr19:37,568,113...37,587,294 		JBrowse link
G Ripor2 RHO family interacting cell polarization regulator 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5887189|PMID:25588844)
(PMID:23241886)		 UniProt
RGD		 PMID:23241886 PMID:25588844 GO_REF:0000024 MGI:5887189 NCBI chr17:42,324,594...42,549,907
Ensembl chr17:42,324,594...42,422,053 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19634
    biological regulation 13612
      regulation of molecular function 3154
        negative regulation of molecular function 1208
          negative regulation of guanyl-nucleotide exchange factor activity 8
            negative regulation of Rho guanyl-nucleotide exchange factor activity 2
Path 2
Term Annotations click to browse term
  biological_process 19634
    biological regulation 13612
      regulation of molecular function 3154
        regulation of catalytic activity 2408
          regulation of hydrolase activity 1225
            regulation of GTPase activity 442
              regulation of guanyl-nucleotide exchange factor activity 13
                negative regulation of guanyl-nucleotide exchange factor activity 8
                  negative regulation of Rho guanyl-nucleotide exchange factor activity 2
paths to the root