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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of vascular associated smooth muscle cell differentiation
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Accession:GO:1905064 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell differentiation.
Synonyms:exact_synonym: down regulation of VSMC differentiation;   down regulation of vascular associated smooth muscle cell differentiation;   down regulation of vascular smooth muscle cell differentiation;   downregulation of VSMC differentiation;   downregulation of vascular associated smooth muscle cell differentiation;   downregulation of vascular smooth muscle cell differentiation;   negative regulation of VSMC differentiation;   negative regulation of vascular smooth muscle cell differentiation
 narrow_synonym: inhibition of VSMC differentiation;   inhibition of vascular associated smooth muscle cell differentiation;   inhibition of vascular smooth muscle cell differentiation



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negative regulation of vascular associated smooth muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MIR15B microRNA mir-15b involved_in ISO (PMID:18548003) BHF-UCL PMID:18548003 NCBI chr34:26,460,663...26,460,722
Ensembl chr34:26,460,645...26,460,741
JBrowse link
G MIR221 microRNA mir-221 involved_in ISO (PMID:18548003), (PMID:19088079) BHF-UCL PMID:18548003 PMID:19088079 NCBI chr  X:39,523,890...39,523,951
Ensembl chr  X:39,523,885...39,523,954
JBrowse link
G MIR26A-1 microRNA mir-26a-1 involved_in ISO (PMID:20857419) BHF-UCL PMID:20857419 NCBI chr23:7,747,073...7,747,133
Ensembl chr23:7,747,064...7,747,140
JBrowse link
G MIR26A-2 microRNA mir-26a-2 involved_in ISO (PMID:20857419) BHF-UCL PMID:20857419 NCBI chr10:1,880,513...1,880,572
Ensembl chr10:1,880,513...1,880,572
JBrowse link
G MIR99A-2 microRNA mir-99a-2 involved_in ISO (PMID:18548003) BHF-UCL PMID:18548003 NCBI chr 5:12,047,369...12,047,425
Ensembl chr 5:12,047,369...12,047,425
JBrowse link
G NFATC1 nuclear factor of activated T cells 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:1,027,021...1,121,362
Ensembl chr 1:1,028,695...1,121,588
JBrowse link
G NFATC2 nuclear factor of activated T cells 2 involved_in ISO (PMID:23853098) BHF-UCL PMID:23853098 NCBI chr24:37,606,977...37,734,813
Ensembl chr24:37,609,561...37,771,132
JBrowse link
G NFATC3 nuclear factor of activated T cells 3 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 5:81,294,656...81,434,256
Ensembl chr 5:81,296,214...81,434,250
JBrowse link
G PDCD4 programmed cell death 4 involved_in ISO (PMID:18548003) BHF-UCL PMID:18548003 NCBI chr28:22,198,274...22,227,184
Ensembl chr28:22,198,322...22,226,717
JBrowse link
G PDGFB platelet derived growth factor subunit B involved_in ISO (PMID:19088079) BHF-UCL PMID:19088079 NCBI chr10:25,798,877...25,819,422
Ensembl chr10:25,798,938...25,817,746
JBrowse link
negative regulation of aortic smooth muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MIR21 microRNA mir-21 involved_in ISO (PMID:22034194) BHF-UCL PMID:22034194 NCBI chr 9:34,340,550...34,340,609
Ensembl chr 9:34,340,533...34,340,624
JBrowse link
negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT1 DNA methyltransferase 1 involved_in ISO (PMID:27021683) BHF-UCL PMID:27021683 NCBI chr20:50,872,213...50,928,352
Ensembl chr20:50,879,527...50,928,029
JBrowse link
G FGF9 fibroblast growth factor 9 involved_in ISO PMID:28259995 BHF-UCL PMID:28259995 RGD:13601993 NCBI chr25:16,630,321...16,665,935
Ensembl chr25:16,632,812...16,663,550
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17343
    cellular process 16322
      negative regulation of cellular process 4980
        negative regulation of cell differentiation 767
          negative regulation of muscle cell differentiation 76
            negative regulation of smooth muscle cell differentiation 22
              negative regulation of vascular associated smooth muscle cell differentiation 13
                negative regulation of aortic smooth muscle cell differentiation 1
                negative regulation of cardiac vascular smooth muscle cell differentiation 0
                negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching 2
Path 2
Term Annotations click to browse term
  biological_process 17343
    developmental process 6659
      anatomical structure development 6204
        multicellular organism development 5063
          system development 4379
            circulatory system development 1316
              vasculature development 861
                vascular associated smooth muscle cell differentiation 50
                  regulation of vascular associated smooth muscle cell differentiation 24
                    negative regulation of vascular associated smooth muscle cell differentiation 13
                      negative regulation of aortic smooth muscle cell differentiation 1
                      negative regulation of cardiac vascular smooth muscle cell differentiation 0
                      negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching 2
paths to the root