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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization
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Accession:GO:1904925 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of autophagy of the mitochondrion in response to mitochondrial depolarization.
Synonyms:exact_synonym: up regulation of mitophagy in response to mitochondrial depolarization;   upregulation of mitophagy in response to mitochondrial depolarization
 narrow_synonym: activation of mitophagy in response to mitochondrial depolarization



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positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp5if1 ATP synthase inhibitory factor subunit 1 involved_in ISO (PMID:24005319) RGD PMID:24005319 NCBI chr 5:144,738,950...144,742,668
Ensembl chr 5:144,738,950...144,742,668
JBrowse link
G Gba glucosylceramidase beta involved_in ISO (MGI:5501380|PMID:23707074) RGD PMID:23707074 MGI:5501380 NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263
JBrowse link
G Hk2 hexokinase 2 involved_in ISO (PMID:23962723) RGD PMID:23962723 NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530
JBrowse link
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 involved_in ISO (MGI:5581539|PMID:24709290) RGD PMID:24709290 MGI:5581539 NCBI chr 5:150,652,812...150,661,863
Ensembl chr 5:150,652,812...150,661,863
JBrowse link
G Pink1 PTEN induced kinase 1 IMP RGD PMID:25154397 RGD:12904014 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vps13c vacuolar protein sorting 13 homolog C involved_in ISO
ISS
(PMID:26942284)
GO_REF:0000024
RGD
ParkinsonsUK-UCL
PMID:26942284 GO_REF:0000024 NCBI chr 8:68,478,366...68,651,893
Ensembl chr 8:68,478,395...68,651,895
JBrowse link
parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdac6 histone deacetylase 6 involved_in ISO UniProtKB:Q9JK66|UniProtKB:Q9Z2V5 (PMID:20457763) RGD PMID:20457763 NCBI chr  X:14,550,645...14,572,445
Ensembl chr  X:14,551,044...14,572,441
JBrowse link
G Mfn2 mitofusin 2 involved_in ISO (MGI:5498413|PMID:23620051) RGD PMID:23620051 MGI:5498413 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
JBrowse link
G Optn optineurin involved_in ISO
IEA
(PMID:25294927)
GO_REF:0000107
RGD
Ensembl
PMID:25294927 GO_REF:0000107 NCBI chr17:73,209,572...73,260,251
Ensembl chr17:73,209,575...73,260,251
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO (PMID:19029340) RGD PMID:19029340 NCBI chr 1:48,688,651...49,882,520 JBrowse link
G Smurf1 SMAD specific E3 ubiquitin protein ligase 1 involved_in ISO (MGI:5298125|PMID:22020285) RGD PMID:22020285 MGI:5298125 NCBI chr12:9,635,009...9,726,520
Ensembl chr12:9,635,025...9,726,519
JBrowse link
positive regulation of mitophagy in response to mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc37 cell division cycle 37, HSP90 cochaperone involved_in IEA
ISO
GO_REF:0000107
(MGI:5607224|PMID:21855797)
Ensembl
RGD
PMID:21855797 GO_REF:0000107 MGI:5607224 NCBI chr 8:19,677,400...19,690,761
Ensembl chr 8:19,671,938...19,690,809
JBrowse link
G Hdac6 histone deacetylase 6 involved_in ISO UniProtKB:Q9JK66 (MGI:5616310|PMID:20457763) RGD PMID:20457763 MGI:5616310 NCBI chr  X:14,550,645...14,572,445
Ensembl chr  X:14,551,044...14,572,441
JBrowse link
G Huwe1 HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 involved_in ISO
IEA
(PMID:30217973)
GO_REF:0000107
RGD
Ensembl
PMID:30217973 GO_REF:0000107 NCBI chr  X:20,871,278...21,001,378
Ensembl chr  X:20,873,795...21,001,262
JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:20871098) RGD PMID:20871098 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO (PMID:20457763), (PMID:20871098), (PMID:23212910) RGD PMID:20457763 PMID:20871098 PMID:23212910 NCBI chr 1:48,688,651...49,882,520 JBrowse link
G Tomm7 translocase of outer mitochondrial membrane 7 involved_in ISO (PMID:24270810) RGD PMID:24270810 NCBI chr 4:11,305,122...11,311,963
Ensembl chr 4:11,305,110...11,311,962
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19390
    cellular process 18252
      process utilizing autophagic mechanism 456
        autophagy 456
          autophagy of mitochondrion 84
            positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization 14
              positive regulation of mitophagy in response to mitochondrial depolarization + 10
Path 2
Term Annotations click to browse term
  biological_process 19390
    cellular process 18252
      cellular component organization or biogenesis 6492
        cellular component organization 6250
          organelle organization 3788
            organelle disassembly 117
              mitochondrion disassembly 84
                autophagy of mitochondrion 84
                  regulation of autophagy of mitochondrion in response to mitochondrial depolarization 15
                    positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization 14
                      positive regulation of mitophagy in response to mitochondrial depolarization + 10
paths to the root