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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of receptor signaling pathway via STAT
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Accession:GO:1904893 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of receptor signaling via STAT.
Synonyms:exact_synonym: down regulation of STAT cascade;   down regulation of STAT signalling pathway;   down regulation of kinase activated-STAT cascade;   down regulation of kinase-STAT cascade;   downregulation of STAT cascade;   downregulation of STAT signalling pathway;   downregulation of kinase activated-STAT cascade;   downregulation of kinase-STAT cascade;   negative regulation of STAT signalling pathway;   negative regulation of kinase activated-STAT cascade;   negative regulation of kinase-STAT cascade
 narrow_synonym: inhibition of STAT cascade;   inhibition of STAT signalling pathway;   inhibition of kinase activated-STAT cascade;   inhibition of kinase-STAT cascade


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negative regulation of receptor signaling pathway via STAT term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pparg peroxisome proliferator-activated receptor gamma acts_upstream_of ISO (PMID:28467929) RGD PMID:28467929 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ptprt protein tyrosine phosphatase, receptor type, T involved_in ISO (PMID:17360477), (PMID:24846175) RGD PMID:17360477 PMID:24846175 NCBI chr 3:157,537,192...158,328,984
Ensembl chr 3:157,544,583...158,328,881
JBrowse link
negative regulation of receptor signaling pathway via JAK-STAT term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipor1 adiponectin receptor 1 involved_in ISO (PMID:23776679) RGD PMID:23776679 NCBI chr13:51,240,470...51,260,233
Ensembl chr13:51,240,911...51,260,228
JBrowse link
G Bcl3 BCL3, transcription coactivator involved_in ISO (PMID:16306601) RGD PMID:16306601 NCBI chr 1:80,730,758...80,745,273
Ensembl chr 1:80,730,499...80,744,831
JBrowse link
G Cav1 caveolin 1 acts_upstream_of_or_within ISO MGI:2180364|MGI:97762 (MGI:3703676|PMID:12388746) RGD PMID:12388746 MGI:3703676 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Dab1 DAB adaptor protein 1 acts_upstream_of_or_within ISO MGI:1857750 (MGI:3839063|PMID:18848628) RGD PMID:18848628 MGI:3839063 NCBI chr 5:123,154,360...124,279,170
Ensembl chr 5:123,905,166...124,280,115
JBrowse link
G Hgs hepatocyte growth factor-regulated tyrosine kinase substrate involved_in ISO
IEA
(PMID:12444102)
GO_REF:0000107
RGD
Ensembl
PMID:12444102 GO_REF:0000107 NCBI chr10:109,638,944...109,657,460
Ensembl chr10:109,638,767...109,657,456
JBrowse link
G Hmga2 high mobility group AT-hook 2 IDA RGD PMID:11390395 RGD:1601592 NCBI chr 7:65,159,944...65,275,408
Ensembl chr 7:65,159,944...65,275,408
JBrowse link
G Leprot leptin receptor overlapping transcript involved_in ISO (PMID:18042720) RGD PMID:18042720 NCBI chr 5:120,498,910...120,511,011
Ensembl chr 5:120,498,883...120,511,017
JBrowse link
G Neurod1 neuronal differentiation 1 acts_upstream_of_or_within ISO (MGI:3839063|PMID:18848628) RGD PMID:18848628 MGI:3839063 NCBI chr 3:66,414,314...66,417,617
Ensembl chr 3:66,414,308...66,417,741
JBrowse link
G Nf2 neurofibromin 2 involved_in ISO (PMID:12444102) RGD PMID:12444102 NCBI chr14:84,996,905...85,088,547
Ensembl chr14:84,996,905...85,088,523
JBrowse link
G Ptprd protein tyrosine phosphatase, receptor type, D acts_upstream_of_or_within ISO MGI:2158795 (MGI:5574540|PMID:24843164) RGD PMID:24843164 MGI:5574540 NCBI chr 5:92,862,229...93,514,071
Ensembl chr 5:92,862,267...93,244,202
JBrowse link
G Sac3d1 SAC3 domain containing 1 acts_upstream_of_or_within ISO (MGI:3831260|PMID:18838617) RGD PMID:18838617 MGI:3831260 NCBI chr 1:221,484,210...221,486,669
Ensembl chr 1:221,484,316...221,486,633
JBrowse link
G Sh2b3 SH2B adaptor protein 3 involved_in ISO (PMID:20404132) RGD PMID:20404132 NCBI chr12:40,261,990...40,265,757
Ensembl chr12:40,244,081...40,265,757
JBrowse link
G Socs1 suppressor of cytokine signaling 1 involved_in
acts_upstream_of_or_within
ISO (PMID:25019494)
MGI:2445448 (MGI:1934707|PMID:11371356)
RGD PMID:11371356 PMID:25019494 MGI:1934707 NCBI chr10:4,956,795...4,958,472
Ensembl chr10:4,957,326...4,958,461
JBrowse link
G Socs2 suppressor of cytokine signaling 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:97763 (MGI:3623843|PMID:16469767)
Ensembl
RGD
PMID:16469767 GO_REF:0000107 MGI:3623843 NCBI chr 7:36,495,496...36,500,878
Ensembl chr 7:36,495,480...36,499,784
JBrowse link
G Socs3 suppressor of cytokine signaling 3 involved_in ISO (PMID:25019494) RGD PMID:25019494 NCBI chr10:106,973,863...106,976,969
Ensembl chr10:106,975,178...106,976,040
JBrowse link
G Vhl von Hippel-Lindau tumor suppressor involved_in ISO (PMID:23338840) RGD PMID:23338840 NCBI chr 4:145,580,869...145,587,835
Ensembl chr 4:145,580,799...145,587,845
JBrowse link
negative regulation of tyrosine phosphorylation of STAT protein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav1 caveolin 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2180364 (MGI:3703676|PMID:12388746)
Ensembl
RGD
PMID:12388746 GO_REF:0000107 MGI:3703676 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Ggnbp2 gametogenetin binding protein 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:4072637 (MGI:5779255|PMID:26764350)
Ensembl
RGD
PMID:26764350 GO_REF:0000107 MGI:5779255 NCBI chr10:72,156,729...72,188,834
Ensembl chr10:72,156,728...72,188,308
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha IDA STAT5b RGD PMID:16584384 RGD:1625011 NCBI chr 3:159,902,441...159,965,003
Ensembl chr 3:159,902,441...159,965,003
JBrowse link
G Inpp5f inositol polyphosphate-5-phosphatase F involved_in ISO (PMID:25476455) RGD PMID:25476455 NCBI chr 1:200,037,749...200,116,524
Ensembl chr 1:200,037,749...200,116,524
JBrowse link
G Irf1 interferon regulatory factor 1 IMP RGD PMID:20980260 RGD:5128774 NCBI chr10:39,109,530...39,116,532
Ensembl chr10:39,109,522...39,116,531
JBrowse link
G Nf2 neurofibromin 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:12444102)
Ensembl
RGD
PMID:12444102 GO_REF:0000107 NCBI chr14:84,996,905...85,088,547
Ensembl chr14:84,996,905...85,088,523
JBrowse link
G Parp14 poly (ADP-ribose) polymerase family, member 14 involved_in ISO (PMID:27796300) RGD PMID:27796300 NCBI chr11:68,105,442...68,137,509
Ensembl chr11:68,105,369...68,137,535
JBrowse link
G Pibf1 progesterone immunomodulatory binding factor 1 involved_in ISO (PMID:16393965) RGD PMID:16393965 NCBI chr15:83,494,110...83,663,202
Ensembl chr15:83,495,377...83,663,143
JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in
NOT|involved_in
ISS
ISO
GO_REF:0000024
(MGI:5493214|PMID:17210636)
(PMID:12138178)
(PMID:12138178), (PMID:12359225), (PMID:17210636)
UniProt
RGD
PMID:12138178 PMID:12359225 PMID:17210636 GO_REF:0000024 MGI:5493214 NCBI chr18:63,415,298...63,489,240
Ensembl chr18:63,415,306...63,488,027
JBrowse link
G Sh2b3 SH2B adaptor protein 3 involved_in IEA
ISO
GO_REF:0000107
(MGI:3510267|PMID:15337790)
Ensembl
RGD
PMID:15337790 GO_REF:0000107 MGI:3510267 NCBI chr12:40,261,990...40,265,757
Ensembl chr12:40,244,081...40,265,757
JBrowse link
G Socs1 suppressor of cytokine signaling 1 involved_in
acts_upstream_of_or_within
ISO
IEA
(PMID:25019494)
GO_REF:0000107
(MGI:1098503|PMID:9202127)
RGD
Ensembl
PMID:9202127 PMID:25019494 GO_REF:0000107 MGI:1098503 NCBI chr10:4,956,795...4,958,472
Ensembl chr10:4,957,326...4,958,461
JBrowse link
G Socs3 suppressor of cytokine signaling 3 involved_in IEA
ISO
GO_REF:0000107
(PMID:25019494)
Ensembl
RGD
PMID:25019494 GO_REF:0000107 NCBI chr10:106,973,863...106,976,969
Ensembl chr10:106,975,178...106,976,040
JBrowse link
G Suz12 SUZ12 polycomb repressive complex 2 subunit IMP RGD PMID:23192652 RGD:9586745 NCBI chr10:67,325,101...67,371,588
Ensembl chr10:67,325,347...67,369,668
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19491
    cellular process 18343
      signal transduction 6881
        negative regulation of signal transduction 1265
          negative regulation of receptor signaling pathway via STAT 26
            negative regulation of receptor signaling pathway via JAK-STAT + 24
Path 2
Term Annotations click to browse term
  biological_process 19491
    biological regulation 13515
      regulation of biological process 12773
        regulation of cellular process 12275
          signal transduction 6881
            cell surface receptor signaling pathway 2774
              receptor signaling pathway via STAT 188
                regulation of receptor signaling pathway via STAT 128
                  negative regulation of receptor signaling pathway via STAT 26
                    negative regulation of receptor signaling pathway via JAK-STAT + 24
paths to the root