Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin protein ligase activity.
Synonyms:
exact_synonym:
down regulation of protein ubiquitination activity; down regulation of ubiquitin ligase activity; down regulation of ubiquitin protein ligase activity; downregulation of protein ubiquitination activity; downregulation of ubiquitin ligase activity; downregulation of ubiquitin protein ligase activity; negative regulation of protein ubiquitination activity; negative regulation of ubiquitin ligase activity
narrow_synonym:
inhibition of protein ubiquitination activity; inhibition of ubiquitin ligase activity; inhibition of ubiquitin protein ligase activity; negative regulation of APC-Cdc20 complex activity; negative regulation of APC-fizzy related complex activity
related_synonym:
down regulation of E3; downregulation of E3; inhibition of E3; negative regulation of APC activity during mitotic cell cycle; negative regulation of APC/C activity during mitotic cell cycle; negative regulation of E3; negative regulation of anaphase-promoting complex activity during mitotic cell cycle; negative regulation of cyclosome activity during mitotic cell cycle; negative regulation of mitotic anaphase-promoting complex activity