Maintaining an endoplasmic reticulum (ER) protein in an unfolded, soluble state that contributes to its degradation by the cytoplasmic proteasome. Maintaining ER-resident proteins in an unfolded yet soluble state condition after their retro-translocation favors their turnover by the cytosolic proteasome.
Synonyms:
exact_synonym:
maintenance of unfolded protein involved in endoplasmic reticulum-associated degradation
related_synonym:
ERAD chaperone-like activity; chaperone holdase activity; holdase activity; maintenance of unfolded protein during ERAD; maintenance of unfolded protein involved in ER-associated degradation pathway; maintenance of unfolded protein involved in endoplasmic reticulum-associated protein degradation pathway