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ONTOLOGY REPORT - ANNOTATIONS

Term:maintenance of unfolded protein involved in ERAD pathway
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Accession:GO:1904378 term browser browse the term
Definition:Maintaining an endoplasmic reticulum (ER) protein in an unfolded, soluble state that contributes to its degradation by the cytoplasmic proteasome. Maintaining ER-resident proteins in an unfolded yet soluble state condition after their retro-translocation favors their turnover by the cytosolic proteasome.
Synonyms:exact_synonym: maintenance of unfolded protein involved in endoplasmic reticulum-associated degradation
 related_synonym: ERAD chaperone-like activity;   chaperone holdase activity;   holdase activity;   maintenance of unfolded protein during ERAD;   maintenance of unfolded protein involved in ER-associated degradation pathway;   maintenance of unfolded protein involved in endoplasmic reticulum-associated protein degradation pathway


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maintenance of unfolded protein involved in ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag6 BAG cochaperone 6 involved_in ISO
IEA		 (PMID:21636303)
GO_REF:0000107		 RGD
Ensembl		 PMID:21636303 GO_REF:0000107 NCBI chr20:3,675,938...3,690,414
Ensembl chr20:3,675,938...3,688,657 		JBrowse link
G Get4 guided entry of tail-anchored proteins factor 4 involved_in ISO (PMID:21636303) RGD PMID:21636303 NCBI chr12:15,377,009...15,394,238
Ensembl chr12:15,377,009...15,394,053 		JBrowse link
G Usp13 ubiquitin specific peptidase 13 involved_in ISO (PMID:24424410) RGD PMID:24424410 NCBI chr 2:115,576,912...115,689,153
Ensembl chr 2:115,577,091...115,686,222 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19574
    biological regulation 13203
      regulation of biological quality 3249
        regulation of protein stability 315
          maintenance of unfolded protein 3
            maintenance of unfolded protein involved in ERAD pathway 3
Path 2
Term Annotations click to browse term
  biological_process 19574
    metabolic process 11556
      catabolic process 2673
        organic substance catabolic process 2270
          organonitrogen compound catabolic process 1350
            protein catabolic process 1022
              proteolysis involved in protein catabolic process 769
                proteasomal protein catabolic process 531
                  ERAD pathway 106
                    maintenance of unfolded protein involved in ERAD pathway 3
paths to the root