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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of telomere maintenance via telomere lengthening
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Accession:GO:1904357 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of telomere maintenance via telomere lengthening.
Synonyms:exact_synonym: down regulation of telomere maintenance via telomere lengthening;   downregulation of telomere maintenance via telomere lengthening
 narrow_synonym: inhibition of telomere maintenance via telomere lengthening


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negative regulation of telomere maintenance via telomere lengthening term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ERCC4 ERCC excision repair 4, endonuclease catalytic subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:29,266,234...29,306,109
Ensembl chr 3:29,269,989...29,306,151 		JBrowse link
G MCRS1 microspherule protein 1 involved_in ISO (PMID:15044100) BHF-UCL PMID:15044100 NCBI chr 5:15,517,028...15,526,567
Ensembl chr 5:15,517,032...15,526,510 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 involved_in ISO (MGI:5705431|PMID:26586427) BHF-UCL PMID:26586427 MGI:5705431 NCBI chr10:14,203,157...14,241,164
Ensembl chr10:14,203,160...14,241,196 		JBrowse link
G SLX1A SLX1 homolog A, structure-specific endonuclease subunit involved_in ISO (PMID:24012755) BHF-UCL PMID:24012755 NCBI chr 3:18,346,501...18,349,509 JBrowse link
G SLX4 SLX4 structure-specific endonuclease subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:38,646,904...38,670,173
Ensembl chr 3:38,646,938...38,670,168 		JBrowse link
G TERF2 telomeric repeat binding factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:17,605,748...17,631,795
Ensembl chr 6:17,605,763...17,631,721 		JBrowse link
G TNKS tankyrase involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:55,513,874...55,681,544
Ensembl chr15:55,514,248...55,681,505 		JBrowse link
G TNKS2 tankyrase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:103,396,424...103,461,830
Ensembl chr14:103,396,459...103,461,821 		JBrowse link
negative regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACD ACD shelterin complex subunit and telomerase recruitment factor involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:28,277,649...28,280,409
Ensembl chr 6:28,277,614...28,280,405 		JBrowse link
G CTC1 CST telomere replication complex component 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:53,427,807...53,454,149
Ensembl chr12:53,428,185...53,454,096 		JBrowse link
G DCP2 decapping mRNA 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:116,736,800...116,804,693
Ensembl chr 2:116,726,243...116,804,613 		JBrowse link
G EXOSC10 exosome component 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:71,258,988...71,282,802
Ensembl chr 6:71,258,999...71,282,433 		JBrowse link
G GNL3L G protein nucleolar 3 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:47,256,467...47,284,520
Ensembl chr  X:47,256,505...47,284,520 		JBrowse link
G HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 involved_in ISO (PMID:23935072) BHF-UCL PMID:23935072 NCBI chr 5:19,485,033...19,491,418
Ensembl chr 5:19,485,096...19,491,417 		JBrowse link
G HNRNPC heterogeneous nuclear ribonucleoprotein C involved_in ISO (PMID:18082603) BHF-UCL PMID:18082603 NCBI chr 7:77,921,098...77,978,550
Ensembl chr 7:77,921,145...77,973,078 		JBrowse link
G HNRNPU heterogeneous nuclear ribonucleoprotein U involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:17,475,266...17,497,060
Ensembl chr10:17,477,902...17,497,030 		JBrowse link
G NAT10 N-acetyltransferase 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:26,786,172...26,827,060
Ensembl chr 2:26,786,177...26,826,992 		JBrowse link
G PIF1 PIF1 5'-to-3' DNA helicase involved_in IEA UniProt
Ensembl		 GO_REF:0000104 GO_REF:0000107 NCBI chr 1:107,218,580...107,227,171
Ensembl chr 1:107,218,657...107,227,168 		JBrowse link
G PINX1 PIN2 (TERF1) interacting telomerase inhibitor 1 involved_in ISO (PMID:11701125)
(PMID:21119197)		 BHF-UCL PMID:11701125 PMID:21119197 NCBI chr14:13,965,733...14,041,841
Ensembl chr14:13,967,070...14,041,788 		JBrowse link
G PML PML nuclear body scaffold involved_in ISO (PMID:19567472) UniProt PMID:19567472 NCBI chr 7:59,405,044...59,450,155
Ensembl chr 7:59,405,053...59,450,105 		JBrowse link
G POT1 protection of telomeres 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:22,885,704...22,981,893
Ensembl chr18:22,885,749...22,981,890 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:40,470,970...40,524,862
Ensembl chr17:40,471,009...40,524,860 		JBrowse link
G STN1 STN1 subunit of CST complex involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:114,808,217...114,851,130
Ensembl chr14:114,810,201...114,851,025 		JBrowse link
G TEN1 TEN1 subunit of CST complex involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr12:5,430,940...5,451,140
Ensembl chr12:5,430,840...5,451,121 		JBrowse link
G TENT4B terminal nucleotidyltransferase 4B involved_in ISO (PMID:26950371) BHF-UCL PMID:26950371 NCBI chr 6:34,603,157...34,669,779
Ensembl chr 6:34,605,529...34,669,278 		JBrowse link
G TERF1 telomeric repeat binding factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:62,797,244...62,831,459
Ensembl chr 4:62,797,000...62,831,454 		JBrowse link
G TERF2 telomeric repeat binding factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:17,605,748...17,631,795
Ensembl chr 6:17,605,763...17,631,721 		JBrowse link
G TINF2 TERF1 interacting nuclear factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:75,056,790...75,067,895
Ensembl chr 7:75,056,798...75,063,979 		JBrowse link
G TP53 tumor protein p53 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,644...52,953,818 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17799
    negative regulation of biological process 5654
      negative regulation of metabolic process 3052
        negative regulation of macromolecule metabolic process 2825
          negative regulation of DNA metabolic process 145
            negative regulation of telomere maintenance 37
              negative regulation of telomere maintenance via telomere lengthening 28
                negative regulation of telomere maintenance via telomerase 21
Path 2
Term Annotations click to browse term
  biological_process 17799
    metabolic process 10358
      organic substance metabolic process 9930
        organic cyclic compound metabolic process 5601
          nucleobase-containing compound metabolic process 5148
            nucleic acid metabolic process 4652
              DNA metabolic process 926
                regulation of DNA metabolic process 467
                  regulation of telomere maintenance 98
                    negative regulation of telomere maintenance 37
                      negative regulation of telomere maintenance via telomere lengthening 28
                        negative regulation of telomere maintenance via telomerase 21
paths to the root