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Pathways
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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of ERAD pathway
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Accession:GO:1904292 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of ERAD pathway.
Synonyms:exact_synonym: regulation of endoplasmic reticulum-associated degradation
 related_synonym: regulation of ER-associated degradation pathway;   regulation of endoplasmic reticulum-associated protein degradation pathway


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regulation of ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:59,388,492...59,400,028
Ensembl chr 2:59,388,494...59,400,003 		JBrowse link
G USP19 ubiquitin specific peptidase 19 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:40,062,802...40,074,221
Ensembl chr20:40,064,599...40,074,082 		JBrowse link
negative regulation of ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP11 aquaporin 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:21,170,760...21,185,709
Ensembl chr21:21,171,008...21,185,429 		JBrowse link
G SGTA small glutamine rich tetratricopeptide repeat co-chaperone alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:56,432,688...56,451,438
Ensembl chr20:56,441,724...56,450,215 		JBrowse link
G SVIP small VCP interacting protein involved_in ISO PMID:17000876
(PMID:17872946)		 ParkinsonsUK-UCL
UniProt		 PMID:17000876 PMID:17872946 RGD:10047192 NCBI chr21:44,408,467...44,418,160
Ensembl chr21:44,408,474...44,415,739 		JBrowse link
G UBXN1 UBX domain protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:53,977,937...53,982,108
Ensembl chr18:53,978,062...53,982,111 		JBrowse link
G UBXN2A UBX domain protein 2A involved_in ISO (PMID:26265139) UniProt PMID:26265139 NCBI chr17:18,446,856...18,491,797
Ensembl chr17:18,408,251...18,505,676 		JBrowse link
G USP14 ubiquitin specific peptidase 14 involved_in ISO (PMID:19135427) ParkinsonsUK-UCL PMID:19135427 NCBI chr 7:67,035,774...67,080,082
Ensembl chr 7:67,035,843...67,079,465 		JBrowse link
G USP25 ubiquitin specific peptidase 25 involved_in IEA Ensembl GO_REF:0000107 NCBI chr31:12,555,614...12,692,765
Ensembl chr31:12,555,595...12,691,694 		JBrowse link
positive regulation of ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATXN3 ataxin 3 involved_in ISO (PMID:17000876) ParkinsonsUK-UCL PMID:17000876 NCBI chr 8:1,318,440...1,354,814
Ensembl chr 8:1,247,155...1,354,720 		JBrowse link
G BAG6 BAG cochaperone 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:1,126,730...1,141,978
Ensembl chr12:1,126,732...1,137,896 		JBrowse link
G BCAP31 B cell receptor associated protein 31 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:121,515,417...121,550,373
Ensembl chr  X:121,507,084...121,545,263 		JBrowse link
G CAV1 caveolin 1 involved_in ISO (PMID:24089527) ParkinsonsUK-UCL PMID:24089527 NCBI chr14:55,458,934...55,494,563
Ensembl chr14:55,461,048...55,492,935 		JBrowse link
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:59,388,492...59,400,028
Ensembl chr 2:59,388,494...59,400,003 		JBrowse link
G RNF185 ring finger protein 185 involved_in ISO (PMID:27485036) UniProt PMID:27485036 NCBI chr26:24,146,172...24,177,747
Ensembl chr26:24,146,005...24,240,653 		JBrowse link
G RNFT1 ring finger protein, transmembrane 1 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr 9:34,430,119...34,442,760
Ensembl chr 9:34,335,554...34,442,374 		JBrowse link
G RNFT2 ring finger protein, transmembrane 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr26:13,410,393...13,500,716
Ensembl chr26:13,412,189...13,638,258 		JBrowse link
G SGTA small glutamine rich tetratricopeptide repeat co-chaperone alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:56,432,688...56,451,438
Ensembl chr20:56,441,724...56,450,215 		JBrowse link
G STUB1 STIP1 homology and U-box containing protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:39,893,492...39,895,385
Ensembl chr 6:39,893,670...39,897,573 		JBrowse link
G TMEM259 transmembrane protein 259 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr20:57,695,004...57,703,650
Ensembl chr20:57,695,002...57,749,891 		JBrowse link
G TMEM67 transmembrane protein 67 ISO RGD PMID:19815549 RGD:8554391 NCBI chr29:38,655,531...38,715,774
Ensembl chr29:38,654,733...38,720,559 		JBrowse link
G TMX1 thioredoxin related transmembrane protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:27,541,407...27,556,058
Ensembl chr 8:27,541,460...27,554,681 		JBrowse link
G UBQLN1 ubiquilin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:75,767,345...75,812,278
Ensembl chr 1:75,767,188...75,838,051 		JBrowse link
G UBQLN2 ubiquilin 2 involved_in ISO (PMID:18307982) UniProt PMID:18307982 NCBI chr  X:47,860,923...47,864,282 JBrowse link
G USP13 ubiquitin specific peptidase 13 involved_in IEA Ensembl GO_REF:0000107 NCBI chr34:13,059,099...13,175,980
Ensembl chr34:13,059,092...13,171,234 		JBrowse link
G WFS1 wolframin ER transmembrane glycoprotein involved_in ISO (PMID:19911006) MGI PMID:19911006 NCBI chr13:38,451,722...38,466,481
Ensembl chr13:38,451,710...38,475,827 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17917
    regulation of biological process 12078
      regulation of cellular process 11571
        regulation of cellular response to stress 510
          regulation of response to endoplasmic reticulum stress 83
            regulation of ERAD pathway 24
              negative regulation of ERAD pathway 7
              positive regulation of ERAD pathway 17
Path 2
Term Annotations click to browse term
  biological_process 17917
    metabolic process 10998
      organic substance metabolic process 10554
        macromolecule metabolic process 8924
          protein metabolic process 4325
            proteolysis 1473
              proteolysis involved in protein catabolic process 786
                proteasomal protein catabolic process 547
                  ERAD pathway 89
                    regulation of ERAD pathway 24
                      negative regulation of ERAD pathway 7
                      positive regulation of ERAD pathway 17
paths to the root