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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of ERAD pathway
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Accession:GO:1904292 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of ERAD pathway.
Synonyms:exact_synonym: regulation of endoplasmic reticulum-associated degradation
 related_synonym: regulation of ER-associated degradation pathway;   regulation of endoplasmic reticulum-associated protein degradation pathway


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regulation of ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Usp19 ubiquitin specific peptidase 19 involved_in ISO
IEA
(PMID:25088257)
GO_REF:0000107
RGD
Ensembl
PMID:25088257 GO_REF:0000107 NCBI chr 8:117,280,690...117,291,729
Ensembl chr 8:117,280,705...117,291,351
JBrowse link
negative regulation of ER-associated ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sgta small glutamine rich tetratricopeptide repeat co-chaperone alpha involved_in ISO
ISS
(PMID:23129660)
GO_REF:0000024
RGD
UniProt
PMID:23129660 GO_REF:0000024 NCBI chr 7:11,521,949...11,538,691
Ensembl chr 7:11,521,998...11,539,319
JBrowse link
G Svip small VCP interacting protein involved_in IBA
ISO
IC
PMID:21873635
(PMID:17872946)
PMID:17000876
RGD PMID:17872946, PMID:21873635, PMID:17000876 RGD:13792537, RGD:10047192 NCBI chr 1:107,368,117...107,373,807
Ensembl chr 1:107,368,117...107,373,807
JBrowse link
G Usp14 ubiquitin specific peptidase 14 involved_in ISO (PMID:19135427) RGD PMID:19135427 NCBI chr18:1,178,785...1,216,573
Ensembl chr18:1,178,787...1,216,409
JBrowse link
negative regulation of ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp11 aquaporin 11 involved_in ISS
ISO
GO_REF:0000024
(MGI:3813160|PMID:18606867)
UniProt
RGD
PMID:18606867 GO_REF:0000024 MGI:3813160 NCBI chr 1:162,703,394...162,713,560
Ensembl chr 1:162,703,442...162,713,610
JBrowse link
G Ubxn1 UBX domain protein 1 involved_in ISO (PMID:21135095) RGD PMID:21135095 NCBI chr 1:225,067,953...225,071,944
Ensembl chr 1:225,068,009...225,071,945
JBrowse link
G Usp25 ubiquitin specific peptidase 25 involved_in ISO (PMID:22590560) RGD PMID:22590560 NCBI chr11:15,436,080...15,558,646
Ensembl chr11:15,436,269...15,558,646
Ensembl chr11:15,436,269...15,558,646
JBrowse link
positive regulation of ER-associated ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcap31 B-cell receptor-associated protein 31 involved_in ISO UniProtKB:Q9BUN8 (PMID:18555783) RGD PMID:18555783 NCBI chr  X:157,094,365...157,126,397
Ensembl chr  X:157,095,937...157,126,393
JBrowse link
G Cav1 caveolin 1 involved_in ISO
IEA
(PMID:24089527)
GO_REF:0000107
RGD
Ensembl
PMID:24089527 GO_REF:0000107 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in ISO
ISS
(PMID:18307982), (PMID:22045699) RGD PMID:18307982 PMID:22045699, PMID:22045699 RGD:10047316 NCBI chr19:11,046,905...11,057,440
Ensembl chr19:11,046,909...11,057,254
JBrowse link
G Sgta small glutamine rich tetratricopeptide repeat co-chaperone alpha involved_in ISO (PMID:23246001) RGD PMID:23246001 NCBI chr 7:11,521,949...11,538,691
Ensembl chr 7:11,521,998...11,539,319
JBrowse link
G Ubqln1 ubiquilin 1 involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:18307982)
Ensembl
UniProt
RGD
PMID:18307982 GO_REF:0000024 GO_REF:0000107 NCBI chr17:6,840,441...6,878,842
Ensembl chr17:6,840,463...6,878,844
JBrowse link
G Ubqln2 ubiquilin 2 involved_in ISO (PMID:18307982) RGD PMID:18307982 NCBI chr  X:18,723,313...18,726,732
Ensembl chr  X:18,723,341...18,726,732
JBrowse link
positive regulation of ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atxn3 ataxin 3 involved_in ISO (PMID:17000876) RGD PMID:17000876 NCBI chr 6:125,817,420...125,853,461
Ensembl chr 6:125,819,640...125,853,461
JBrowse link
G Bag6 BAG cochaperone 6 involved_in ISO (PMID:24424410) RGD PMID:24424410 NCBI chr20:5,124,512...5,138,084
Ensembl chr20:5,125,349...5,138,084
JBrowse link
G Rnf185 ring finger protein 185 involved_in ISO
ISS
(PMID:27485036)
GO_REF:0000024
RGD
UniProt
PMID:27485036 GO_REF:0000024 NCBI chr14:83,648,400...83,685,273
Ensembl chr14:83,648,402...83,685,273
JBrowse link
G Rnft1 ring finger protein, transmembrane 1 involved_in ISO
IBA
(PMID:27485036)
PMID:21873635
RGD PMID:27485036, PMID:21873635 RGD:13792537 NCBI chr10:73,807,455...73,821,178
Ensembl chr10:73,809,157...73,817,982
JBrowse link
G Rnft2 ring finger protein, transmembrane 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr12:43,940,929...44,008,685
Ensembl chr12:43,940,929...44,008,685
JBrowse link
G Tmem259 transmembrane protein 259 involved_in IBA
ISO
PMID:21873635
(MGI:5648655|PMID:25977983)
RGD PMID:25977983, PMID:21873635 MGI:5648655, RGD:13792537 NCBI chr 7:12,771,239...12,777,901
Ensembl chr 7:12,771,227...12,779,862
JBrowse link
G Tmem67 transmembrane protein 67 IMP RGD PMID:19815549 RGD:8554391 NCBI chr 5:25,666,138...25,721,056
Ensembl chr 5:25,666,137...25,721,072
JBrowse link
G Usp13 ubiquitin specific peptidase 13 involved_in ISO (PMID:24424410) RGD PMID:24424410 NCBI chr 2:119,197,153...119,317,507
Ensembl chr 2:119,197,239...119,317,500
JBrowse link
regulation of ER-associated ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in IBA
ISO
PMID:21873635
(MGI:5613477|PMID:15147274)
RGD PMID:15147274, PMID:21873635 MGI:5613477, RGD:13792537 NCBI chr19:11,046,905...11,057,440
Ensembl chr19:11,046,909...11,057,254
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19610
    cellular process 18463
      regulation of cellular process 12352
        regulation of cellular response to stress 681
          regulation of response to endoplasmic reticulum stress 82
            regulation of ERAD pathway 20
              negative regulation of ERAD pathway + 6
              positive regulation of ERAD pathway + 14
              regulation of ER-associated ubiquitin-dependent protein catabolic process + 8
Path 2
Term Annotations click to browse term
  biological_process 19610
    biological regulation 13577
      regulation of biological process 12853
        regulation of metabolic process 6774
          regulation of primary metabolic process 5787
            regulation of protein metabolic process 2680
              regulation of cellular protein metabolic process 2506
                regulation of cellular protein catabolic process 257
                  regulation of proteolysis involved in cellular protein catabolic process 224
                    regulation of proteasomal protein catabolic process 189
                      regulation of ERAD pathway 20
                        negative regulation of ERAD pathway + 6
                        positive regulation of ERAD pathway + 14
                        regulation of ER-associated ubiquitin-dependent protein catabolic process + 8
paths to the root