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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of serine C-palmitoyltransferase activity
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Accession:GO:1904222 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of serine C-palmitoyltransferase activity.
Comment:Serinc proteins form a complex with serine and sphingolipid biosynthesis enzymes and regulates their activity through regulation of the substrate availability
Synonyms:exact_synonym: positive regulation of 3-oxosphinganine synthetase activity;   positive regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity;   up regulation of 3-oxosphinganine synthetase activity;   up regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity;   up regulation of serine C-palmitoyltransferase activity;   upregulation of 3-oxosphinganine synthetase activity;   upregulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity;   upregulation of serine C-palmitoyltransferase activity
 narrow_synonym: activation of 3-oxosphinganine synthetase activity;   activation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity;   activation of serine C-palmitoyltransferase activity
 related_synonym: activation of SPT;   activation of acyl-CoA:serine C-2 acyltransferase decarboxylating;   positive regulation of SPT;   positive regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating;   up regulation of SPT;   up regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating;   upregulation of SPT;   upregulation of acyl-CoA:serine C-2 acyltransferase decarboxylating



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positive regulation of serine C-palmitoyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Serinc1 serine incorporator 1 involved_in IDA PMID:16120614 BHF-UCL PMID:16120614 RGD:8553290 NCBI chr20:36,850,062...36,896,691
Ensembl chr20:36,850,076...36,896,691
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G Serinc2 serine incorporator 2 involved_in IDA PMID:16120614 BHF-UCL PMID:16120614 RGD:8553290 NCBI chr 5:142,592,308...142,614,628
Ensembl chr 5:142,592,309...142,618,364
JBrowse link
G Serinc5 serine incorporator 5 involved_in IDA PMID:16120614 BHF-UCL PMID:16120614 RGD:8553290 NCBI chr 2:23,846,899...23,950,346
Ensembl chr 2:23,846,900...23,950,346
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  biological_process 18877
    biological regulation 13380
      regulation of molecular function 3136
        positive regulation of molecular function 1606
          positive regulation of catalytic activity 1169
            positive regulation of transferase activity 592
              positive regulation of serine C-palmitoyltransferase activity 3
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