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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity
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Accession:GO:1904218 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of CDP-diacylglycerol-serine O-phosphatidyltransferase activity.
Comment:Serinc proteins form a complex with serine and sphingolipid biosynthesis enzymes and regulates their activity through regulation of availability of the substrate
Synonyms:exact_synonym: down regulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity;   down regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity;   down regulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity;   down regulation of CDP-diglyceride-L-serine phosphatidyltransferase activity;   down regulation of CDP-diglyceride:serine phosphatidyltransferase activity;   down regulation of CDP-diglycerine-serine O-phosphatidyltransferase activity;   down regulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity;   down regulation of CDPdiglyceride-serine O-phosphatidyltransferase activity;   down regulation of PS synthase activity;   down regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity;   down regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity;   down regulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity;   down regulation of phosphatidylserine synthase activity;   down regulation of phosphatidylserine synthetase activity;   downregulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity;   downregulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity;   downregulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity;   downregulation of CDP-diglyceride-L-serine phosphatidyltransferase activity;   downregulation of CDP-diglyceride:serine phosphatidyltransferase activity;   downregulation of CDP-diglycerine-serine O-phosphatidyltransferase activity;   downregulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity;   downregulation of CDPdiglyceride-serine O-phosphatidyltransferase activity;   downregulation of PS synthase activity;   downregulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity;   downregulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity;   downregulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity;   downregulation of phosphatidylserine synthase activity;   downregulation of phosphatidylserine synthetase activity;   negative regulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity;   negative regulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity;   negative regulation of CDP-diglyceride-L-serine phosphatidyltransferase activity;   negative regulation of CDP-diglyceride:serine phosphatidyltransferase activity;   negative regulation of CDP-diglycerine-serine O-phosphatidyltransferase activity;   negative regulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity;   negative regulation of CDPdiglyceride-serine O-phosphatidyltransferase activity;   negative regulation of PS synthase activity;   negative regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity;   negative regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity;   negative regulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity;   negative regulation of phosphatidylserine synthase activity;   negative regulation of phosphatidylserine synthetase activity
 narrow_synonym: inhibition of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity;   inhibition of CDP-diacylglycerol-serine O-phosphatidyltransferase activity;   inhibition of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity;   inhibition of CDP-diglyceride-L-serine phosphatidyltransferase activity;   inhibition of CDP-diglyceride:serine phosphatidyltransferase activity;   inhibition of CDP-diglycerine-serine O-phosphatidyltransferase activity;   inhibition of CDPdiacylglycerol-serine O-phosphatidyltransferase activity;   inhibition of CDPdiglyceride-serine O-phosphatidyltransferase activity;   inhibition of PS synthase activity;   inhibition of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity;   inhibition of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity;   inhibition of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity;   inhibition of phosphatidylserine synthase activity;   inhibition of phosphatidylserine synthetase activity



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  biological_process 18734
    biological regulation 13314
      regulation of molecular function 3108
        negative regulation of molecular function 1234
          negative regulation of catalytic activity 810
            negative regulation of transferase activity 290
              negative regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity 0
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