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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of pyruvate dehydrogenase activity
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Accession:GO:1904183 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of pyruvate dehydrogenase activity.
Synonyms:exact_synonym: down regulation of pyruvate dehydrogenase activity;   down regulation of pyruvic acid dehydrogenase activity;   down regulation of pyruvic dehydrogenase activity;   downregulation of pyruvate dehydrogenase activity;   downregulation of pyruvic acid dehydrogenase activity;   downregulation of pyruvic dehydrogenase activity;   negative regulation of pyruvic acid dehydrogenase activity;   negative regulation of pyruvic dehydrogenase activity
 narrow_synonym: inhibition of pyruvate dehydrogenase activity;   inhibition of pyruvic acid dehydrogenase activity;   inhibition of pyruvic dehydrogenase activity


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negative regulation of pyruvate dehydrogenase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bckdk branched chain ketoacid dehydrogenase kinase IBA (MGI:MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:MGI:6201960 NCBI chr 7:127,904,073...127,909,664
Ensembl chr 7:127,904,082...127,910,221
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase, isoenzyme 1 IBA (MGI:MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:MGI:6201960 NCBI chr 2:71,873,215...71,903,858
Ensembl chr 2:71,873,224...71,903,858
JBrowse link
G Pdk2 pyruvate dehydrogenase kinase, isoenzyme 2 IBA (MGI:MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:MGI:6201960 NCBI chr11:95,026,258...95,041,371
Ensembl chr11:95,026,258...95,041,354
JBrowse link
G Pdk3 pyruvate dehydrogenase kinase, isoenzyme 3 IBA (MGI:MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:MGI:6201960 NCBI chr  X:93,764,616...93,832,150
Ensembl chr  X:93,764,607...93,832,201
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase, isoenzyme 4 IBA (MGI:MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:MGI:6201960 NCBI chr 6:5,483,351...5,496,278
Ensembl chr 6:5,483,351...5,496,309
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23366
    negative regulation of biological process 5680
      negative regulation of metabolic process 3250
        negative regulation of oxidoreductase activity 34
          negative regulation of pyruvate dehydrogenase activity 5
Path 2
Term Annotations click to browse term
  biological_process 23366
    biological regulation 13064
      regulation of molecular function 2716
        regulation of catalytic activity 1994
          negative regulation of catalytic activity 729
            negative regulation of oxidoreductase activity 34
              negative regulation of pyruvate dehydrogenase activity 5
paths to the root

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