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ONTOLOGY REPORT - ANNOTATIONS


Term:presynaptic active zone assembly
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Accession:GO:1904071 term browser browse the term
Definition:The aggregation, arrangement and bonding together of a set of components to form a presynaptic active zone. The presynaptic active zone is a specialized region of the plasma membrane and cell cortex of a presynaptic neuron; encompasses a region of the plasma membrane where synaptic vesicles dock and fuse, and a specialized cortical cytoskeletal matrix.
Synonyms:exact_synonym: pre-synaptic active zone assembly;   pre-synaptic active zone formation;   presynaptic active zone formation
 narrow_synonym: pre-synaptic active zone component assembly;   pre-synaptic active zone component formation


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presynaptic active zone assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bsn bassoon presynaptic cytomatrix protein involved_in ISO PMID:22875941 UniProt PMID:22875941 RGD:14390063 NCBI chrNW_004955532:1,527,336...1,578,394
Ensembl chrNW_004955532:1,527,477...1,570,670
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G Pcdh17 protocadherin 17 acts_upstream_of_or_within ISO (MGI:5514320|PMID:23684785) MGI PMID:23684785 MGI:5514320 NCBI chrNW_004955404:46,795,303...46,886,918
Ensembl chrNW_004955404:46,791,148...46,886,918
JBrowse link
G Pclo piccolo presynaptic cytomatrix protein involved_in ISO PMID:22875941 UniProt PMID:22875941 RGD:14390063 NCBI chrNW_004955410:2,998,345...3,334,056
Ensembl chrNW_004955410:3,152,202...3,292,920
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positive regulation of presynaptic active zone assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nlgn1 neuroligin 1 involved_in ISO PMID:15797875 BHF-UCL PMID:15797875 RGD:8554205 NCBI chrNW_004955420:3,360,745...4,171,587
Ensembl chrNW_004955420:3,549,021...4,167,493
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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12106
    cellular process 11339
      cellular component organization or biogenesis 4918
        cellular component organization 4833
          cellular component assembly 2324
            presynaptic active zone assembly 4
              negative regulation of presynaptic active zone assembly 0
              positive regulation of presynaptic active zone assembly 1
              regulation of presynaptic active zone assembly + 1
Path 2
Term Annotations click to browse term
  biological_process 12106
    cellular process 11339
      cellular component organization or biogenesis 4918
        cellular component organization 4833
          cellular component assembly 2324
            cell junction assembly 387
              synapse assembly 187
                presynapse assembly 47
                  presynaptic active zone assembly 4
                    negative regulation of presynaptic active zone assembly 0
                    positive regulation of presynaptic active zone assembly 1
                    regulation of presynaptic active zone assembly + 1
paths to the root