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ONTOLOGY REPORT - ANNOTATIONS


Term:presynaptic active zone assembly
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Accession:GO:1904071 term browser browse the term
Definition:The aggregation, arrangement and bonding together of a set of components to form a presynaptic active zone. The presynaptic active zone is a specialized region of the plasma membrane and cell cortex of a presynaptic neuron; encompasses a region of the plasma membrane where synaptic vesicles dock and fuse, and a specialized cortical cytoskeletal matrix.
Synonyms:exact_synonym: pre-synaptic active zone assembly;   pre-synaptic active zone formation;   presynaptic active zone formation
 narrow_synonym: pre-synaptic active zone component assembly;   pre-synaptic active zone component formation



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presynaptic active zone assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bsn bassoon (presynaptic cytomatrix protein) involved_in IDA
IBA
PMID:22875941
PMID:21873635
UniProt
GO_Central
PMID:22875941 PMID:21873635 RGD:14390063, RGD:13792537 NCBI chr 8:108,784,849...108,875,819
Ensembl chr 8:108,788,542...108,875,819
JBrowse link
G Pcdh17 protocadherin 17 acts_upstream_of_or_within ISO (MGI:5514320|PMID:23684785) RGD PMID:23684785 MGI:5514320 NCBI chr15:60,222,088...60,316,172
Ensembl chr15:60,222,004...60,313,999
JBrowse link
G Pclo piccolo (presynaptic cytomatrix protein) involved_in IBA
IDA
PMID:21873635
PMID:22875941
GO_Central
UniProt
PMID:21873635 PMID:22875941 RGD:13792537, RGD:14390063 NCBI chr 4:19,691,439...20,050,015
Ensembl chr 4:19,695,315...20,049,885
JBrowse link
positive regulation of presynaptic active zone assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nlgn1 neuroligin 1 involved_in IDA PMID:15797875 BHF-UCL PMID:15797875 RGD:8554205 NCBI chr 2:108,256,236...109,181,530
Ensembl chr 2:108,257,824...109,002,464
JBrowse link
G Nrxn1 neurexin 1 involved_in TAS PMID:15797875 BHF-UCL PMID:15797875 RGD:8554205 NCBI chr 6:3,177,788...4,323,848
Ensembl chr 6:3,177,897...4,322,710
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    cellular process 18359
      cellular component organization or biogenesis 6620
        cellular component organization 6378
          cellular component assembly 3088
            presynaptic active zone assembly 5
              negative regulation of presynaptic active zone assembly 0
              positive regulation of presynaptic active zone assembly 2
              regulation of presynaptic active zone assembly + 2
Path 2
Term Annotations click to browse term
  biological_process 19497
    cellular process 18359
      cellular component organization or biogenesis 6620
        cellular component organization 6378
          cellular component assembly 3088
            cell junction assembly 461
              synapse assembly 196
                presynapse assembly 52
                  presynaptic active zone assembly 5
                    negative regulation of presynaptic active zone assembly 0
                    positive regulation of presynaptic active zone assembly 2
                    regulation of presynaptic active zone assembly + 2
paths to the root