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ONTOLOGY REPORT - ANNOTATIONS


Term:presynaptic active zone assembly
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Accession:GO:1904071 term browser browse the term
Definition:The aggregation, arrangement and bonding together of a set of components to form a presynaptic active zone. The presynaptic active zone is a specialized region of the plasma membrane and cell cortex of a presynaptic neuron; encompasses a region of the plasma membrane where synaptic vesicles dock and fuse, and a specialized cortical cytoskeletal matrix.
Synonyms:exact_synonym: pre-synaptic active zone assembly;   pre-synaptic active zone formation;   presynaptic active zone formation
 narrow_synonym: pre-synaptic active zone component assembly;   pre-synaptic active zone component formation


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presynaptic active zone assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bsn bassoon (presynaptic cytomatrix protein) IDA
IBA
PMID:22875941
PMID:21873635
UniProt
GO_Central
PMID:22875941, PMID:21873635 RGD:14390063, RGD:13792537 NCBI chr 8:116,873,721...116,965,396
Ensembl chr 8:116,873,721...116,965,396
JBrowse link
G Pcdh17 protocadherin 17 ISO (MGI:5514320|PMID:23684785) RGD PMID:23684785 MGI:5514320 NCBI chr15:67,555,835...67,647,990
Ensembl chr15:67,555,835...67,645,088
JBrowse link
G Pclo piccolo (presynaptic cytomatrix protein) IDA
IBA
PMID:22875941
PMID:21873635
UniProt
GO_Central
PMID:22875941, PMID:21873635 RGD:14390063, RGD:13792537 NCBI chr 4:16,454,904...17,058,921
Ensembl chr 4:16,454,904...17,058,921
JBrowse link
positive regulation of presynaptic active zone assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nlgn1 neuroligin 1 IDA PMID:15797875 BHF-UCL PMID:15797875 RGD:8554205 NCBI chr 2:111,057,291...111,973,681
Ensembl chr 2:111,057,291...111,793,326
JBrowse link
G Nrxn1 neurexin 1 TAS PMID:15797875 BHF-UCL PMID:15797875 RGD:8554205 NCBI chr 6:13,886,757...15,191,660
Ensembl chr 6:13,886,740...15,191,660
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20044
    cellular process 18858
      cellular component organization or biogenesis 6787
        cellular component organization 6534
          cellular component assembly 2986
            presynaptic active zone assembly 5
              negative regulation of presynaptic active zone assembly 0
              positive regulation of presynaptic active zone assembly 2
              regulation of presynaptic active zone assembly + 2
Path 2
Term Annotations click to browse term
  biological_process 20044
    cellular process 18858
      cellular component organization or biogenesis 6787
        cellular component organization 6534
          cellular component assembly 2986
            cell junction assembly 454
              synapse assembly 197
                presynapse assembly 52
                  presynaptic active zone assembly 5
                    negative regulation of presynaptic active zone assembly 0
                    positive regulation of presynaptic active zone assembly 2
                    regulation of presynaptic active zone assembly + 2
paths to the root