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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of cation transmembrane transport
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Accession:GO:1904063 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of cation transmembrane transport.
Synonyms:exact_synonym: down regulation of cation transmembrane transport;   downregulation of cation transmembrane transport
 narrow_synonym: inhibition of cation transmembrane transport


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negative regulation of calcium import into the mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 ISO RGD PMID:24601882 RGD:39128160
G VDAC1 voltage dependent anion channel 1 involved_in ISO (PMID:32047033) UniProt PMID:32047033 NCBI chr 2:136,302,188...136,334,461
Ensembl chr 2:136,302,191...136,396,301 		JBrowse link
negative regulation of calcium ion export across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CALM1 calmodulin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:112,160,823...112,171,754
Ensembl chr 7:112,160,806...112,171,744 		JBrowse link
G CALM2 calmodulin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:93,371,765...93,386,378
Ensembl chr 3:93,372,045...93,386,218 		JBrowse link
G CALM3 calmodulin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:52,506,979...52,516,704
Ensembl chr 6:52,506,674...52,516,703 		JBrowse link
G YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:47,601,133...47,645,327
Ensembl chr12:47,600,745...47,645,301 		JBrowse link
negative regulation of calcium ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAV1 caveolin 1 ISO RGD PMID:29069575 RGD:151347449 NCBI chr18:29,648,120...29,682,451
Ensembl chr18:29,649,992...29,682,465 		JBrowse link
G MIR208B microRNA mir-208b involved_in ISO (PMID:27545043) BHF-UCL PMID:27545043 NCBI chr 7:75,667,786...75,667,865
Ensembl chr 7:75,667,786...75,667,865 		JBrowse link
negative regulation of calcium ion transmembrane transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHR aryl hydrocarbon receptor ISO RGD PMID:12193573 RGD:625678 NCBI chr 9:86,511,866...86,555,950
Ensembl chr 9:86,511,369...86,555,943 		JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 involved_in ISO PMID:17442282 BHF-UCL PMID:17442282 RGD:6903343 NCBI chr 4:90,341,316...90,371,040
Ensembl chr 4:90,341,322...90,370,996 		JBrowse link
G CBARP CACN subunit beta associated regulatory protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:77,220,790...77,230,418
Ensembl chr 2:77,220,972...77,230,058 		JBrowse link
G PTGER3 prostaglandin E receptor 3 ISO RGD PMID:10670413 RGD:10043333 NCBI chr 6:141,958,955...142,160,437
Ensembl chr 6:141,958,955...142,161,286 		JBrowse link
negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BIN1 bridging integrator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:25,328,679...25,379,675
Ensembl chr15:25,328,674...25,383,652 		JBrowse link
G FBXO11 F-box protein 11 ISO RGD PMID:32988261 RGD:152176655 NCBI chr 3:92,696,402...92,792,623
Ensembl chr 3:92,696,441...92,792,616 		JBrowse link
G REM1 RRAD and GEM like GTPase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:26078055) Ensembl
MGI		 PMID:26078055 GO_REF:0000107 NCBI chr17:35,208,344...35,218,771
Ensembl chr17:35,208,363...35,218,768 		JBrowse link
G SESTD1 SEC14 and spectrin domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:84,762,923...84,892,580
Ensembl chr15:84,760,451...84,849,319 		JBrowse link
G UBR3 ubiquitin protein ligase E3 component n-recognin 3 ISO RGD PMID:32988261 RGD:152176655 NCBI chr15:76,135,456...76,360,819
Ensembl chr15:76,135,494...76,360,823 		JBrowse link
negative regulation of calcium ion transmembrane transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PPP2CA protein phosphatase 2 catalytic subunit alpha ISO RGD PMID:15728831 RGD:8554004 NCBI chr 2:136,497,780...136,522,630
Ensembl chr 2:136,494,541...136,522,646 		JBrowse link
negative regulation of calcium ion transport into cytosol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL2 BCL2 apoptosis regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15613488) Ensembl
MGI		 PMID:15613488 GO_REF:0000107 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879 		JBrowse link
G CALCB calcitonin-related polypeptide beta involved_in ISO (PMID:16014619) UniProt PMID:16014619 NCBI chr 2:44,043,135...44,048,651 JBrowse link
G EPO erythropoietin involved_in ISO (PMID:14569084) BHF-UCL PMID:14569084 NCBI chr 3:8,620,508...8,622,936
Ensembl chr 3:8,620,508...8,622,936 		JBrowse link
G TMBIM6 transmembrane BAX inhibitor motif containing 6 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:26582200) MGI
Ensembl		 PMID:26582200 GO_REF:0000107 NCBI chr 5:15,674,028...15,692,944
Ensembl chr 5:15,674,057...15,692,936 		JBrowse link
negative regulation of cation channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAV1 caveolin 1 ISO RGD PMID:20624795 RGD:6849299 NCBI chr18:29,648,120...29,682,451
Ensembl chr18:29,649,992...29,682,465 		JBrowse link
G FGF12 fibroblast growth factor 12 ISO RGD PMID:12401812 RGD:6484231 NCBI chr13:129,237,500...129,817,992
Ensembl chr13:129,240,083...129,817,911 		JBrowse link
negative regulation of delayed rectifier potassium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNAB1 potassium voltage-gated channel subfamily A regulatory beta subunit 1 ISO RGD PMID:8183366 PMID:8799886 RGD:61642 RGD:9743956 NCBI chr13:95,981,820...96,375,089
Ensembl chr13:95,959,378...96,375,856 		JBrowse link
G MTNR1B melatonin receptor 1B ISO RGD PMID:14962062 RGD:9588668 NCBI chr 9:25,556,756...25,557,792
Ensembl chr 9:25,545,390...25,558,054 		JBrowse link
negative regulation of inward rectifier potassium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SNX27 sorting nexin 27 ISO RGD PMID:21422294 RGD:8554349 NCBI chr 4:97,533,643...97,620,816
Ensembl chr 4:97,525,181...97,620,788 		JBrowse link
negative regulation of iron export across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HAMP hepcidin antimicrobial peptide involved_in ISO (PMID:15514116) BHF-UCL PMID:15514116 NCBI chr 6:44,785,863...44,787,303
Ensembl chr 6:44,784,160...44,787,305 		JBrowse link
negative regulation of iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ISCU iron-sulfur cluster assembly enzyme involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:42,216,103...42,222,570
Ensembl chr14:42,216,111...42,222,711 		JBrowse link
negative regulation of iron ion transmembrane transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP7A ATPase copper transporting alpha ISO RGD PMID:24174620 RGD:11341686 NCBI chr  X:61,972,544...62,110,058
Ensembl chr  X:61,972,991...62,110,048 		JBrowse link
G HAMP hepcidin antimicrobial peptide involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:21700773) TreeGrafter
MGI
GO_Central		 PMID:21700773 GO_REF:0000033 GO_REF:0000118 NCBI chr 6:44,785,863...44,787,303
Ensembl chr 6:44,784,160...44,787,305 		JBrowse link
G NOS1 nitric oxide synthase 1 ISO RGD PMID:14752097 RGD:13824992 NCBI chr14:35,112,898...35,299,297
Ensembl chr14:35,113,184...35,295,944 		JBrowse link
negative regulation of P-type sodium:potassium-exchanging transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FXYD2 FXYD domain containing ion transport regulator 2 ISO RGD PMID:15280368 RGD:1598989 NCBI chr 9:45,165,314...45,172,440 JBrowse link
negative regulation of potassium ion export across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNE3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:8,810,716...8,822,191
Ensembl chr 9:8,810,720...8,822,494 		JBrowse link
G KCNE5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:89,741,187...89,742,732
Ensembl chr  X:89,741,190...89,742,672 		JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:6,242,826...6,279,154
Ensembl chr18:6,243,524...6,279,111 		JBrowse link
negative regulation of potassium ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MIR103-1 microRNA mir-103-1 involved_in ISO (PMID:27558843) BHF-UCL PMID:27558843 NCBI chr16:55,329,442...55,329,523
Ensembl chr16:55,329,442...55,329,523 		JBrowse link
G MIR103-2 microRNA mir-103-2 involved_in ISO (PMID:27558843) BHF-UCL PMID:27558843 NCBI chr17:31,808,837...31,808,916
Ensembl chr17:31,808,836...31,808,920 		JBrowse link
negative regulation of potassium ion transmembrane transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BIN1 bridging integrator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:25,328,679...25,379,675
Ensembl chr15:25,328,674...25,383,652 		JBrowse link
G CAV1 caveolin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:29,648,120...29,682,451
Ensembl chr18:29,649,992...29,682,465 		JBrowse link
G CAV3 caveolin 3 involved_in ISO PMID:22879586 BHF-UCL PMID:22879586 RGD:8553349 NCBI chr13:65,117,868...65,130,886
Ensembl chr13:65,117,795...65,131,273 		JBrowse link
G KCNE5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:89,741,187...89,742,732
Ensembl chr  X:89,741,190...89,742,672 		JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:6,242,826...6,279,154
Ensembl chr18:6,243,524...6,279,111 		JBrowse link
G KEL Kell metallo-endopeptidase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19544475) Ensembl
MGI		 PMID:19544475 GO_REF:0000107 NCBI chr18:7,242,378...7,279,345
Ensembl chr18:7,259,144...7,279,328 		JBrowse link
G MIR29B-1 microRNA mir-29b-1 involved_in ISO (PMID:31553627) BHF-UCL PMID:31553627 NCBI chr18:18,039,629...18,039,709
Ensembl chr18:18,039,629...18,039,709 		JBrowse link
G MIR29B-2 microRNA mir-29b-2 involved_in ISO (PMID:31553627) BHF-UCL PMID:31553627 NCBI chr 9:135,019,079...135,019,162
Ensembl chr 9:135,019,075...135,019,164 		JBrowse link
G NEDD4L NEDD4 like E3 ubiquitin protein ligase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:162,364,053...162,736,515
Ensembl chr 1:162,364,057...162,513,718 		JBrowse link
G OXSR1 oxidative stress responsive kinase 1 involved_in ISO (MGI:5574433|PMID:24393035) ParkinsonsUK-UCL PMID:24393035 MGI:5574433 NCBI chr13:23,020,839...23,116,957
Ensembl chr13:23,020,530...23,116,958 		JBrowse link
G PTGER3 prostaglandin E receptor 3 ISO RGD PMID:18496512 RGD:10043331 NCBI chr 6:141,958,955...142,160,437
Ensembl chr 6:141,958,955...142,161,286 		JBrowse link
G RGS4 regulator of G protein signaling 4 ISO RGD PMID:24421355 RGD:11064811 NCBI chr 4:87,383,336...87,390,478
Ensembl chr 4:87,383,345...87,390,893 		JBrowse link
G STK39 serine/threonine kinase 39 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:74,441,019...74,757,851
Ensembl chr15:74,447,787...74,758,122 		JBrowse link
negative regulation of potassium ion transmembrane transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTEN phosphatase and tensin homolog ISO RGD PMID:24103758 RGD:12802338 NCBI chr14:99,929,590...100,021,619 JBrowse link
negative regulation of release of sequestered calcium ion into cytosol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FCRL5 Fc receptor like 5 acts_upstream_of_or_within ISO (PMID:23509253) MGI PMID:23509253 NCBI chr 4:92,578,672...92,631,713 JBrowse link
G FKBP1A FKBP prolyl isomerase 1A NOT|involved_in ISO (PMID:12443530) BHF-UCL PMID:12443530 NCBI chr17:33,910,047...33,935,212 JBrowse link
G FKBP1B FKBP prolyl isomerase 1B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:114,623,529...114,636,200
Ensembl chr 3:114,623,532...114,634,628 		JBrowse link
G NTSR1 neurotensin receptor 1 ISO RGD PMID:12084713 RGD:727385 NCBI chr17:61,989,601...62,038,299
Ensembl chr17:61,989,402...62,033,548 		JBrowse link
G PRKCE protein kinase C epsilon involved_in ISO PMID:20383739 UniProt PMID:20383739 RGD:7206836 NCBI chr 3:94,351,277...94,864,549
Ensembl chr 3:94,349,889...94,866,306 		JBrowse link
G TGFB1 transforming growth factor beta 1 ISO RGD PMID:12876066 RGD:731229 NCBI chr 6:49,332,169...49,348,642
Ensembl chr 6:49,332,173...49,349,046 		JBrowse link
G TGFB2 transforming growth factor beta 2 ISO RGD PMID:12876066 RGD:731229 NCBI chr10:8,306,136...8,435,307
Ensembl chr10:8,305,539...8,390,341 		JBrowse link
G TRDN triadin ISO RGD PMID:16176928 RGD:7327230 NCBI chr 1:39,180,544...39,567,245
Ensembl chr 1:39,180,913...39,567,240 		JBrowse link
negative regulation of sodium ion export across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGRN agrin involved_in ISO (MGI:4352602|PMID:19376779) BHF-UCL PMID:19376779 MGI:4352602 NCBI chr 6:63,366,017...63,398,311
Ensembl chr 6:63,365,983...63,398,309 		JBrowse link
negative regulation of sodium ion transmembrane transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAMK2D calcium/calmodulin dependent protein kinase II delta involved_in ISO (PMID:22514276) BHF-UCL PMID:22514276 NCBI chr 8:108,916,019...109,221,317
Ensembl chr 8:108,915,572...109,222,905 		JBrowse link
G COMMD1 copper metabolism domain containing 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:79,770,315...79,913,969
Ensembl chr 3:79,770,463...79,913,975 		JBrowse link
G MIR192 microRNA mir-192 acts_upstream_of ISO (PMID:26209011) BHF-UCL PMID:26209011 NCBI chr 2:7,285,667...7,285,746
Ensembl chr 2:7,285,667...7,285,746 		JBrowse link
G NEDD4L NEDD4 like E3 ubiquitin protein ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:162,364,053...162,736,515
Ensembl chr 1:162,364,057...162,513,718 		JBrowse link
negative regulation of sodium:proton antiporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DRD3 dopamine receptor D3 ISO RGD PMID:15265811 RGD:1625070 NCBI chr13:145,769,294...145,817,997
Ensembl chr13:145,771,774...145,819,168 		JBrowse link
negative regulation of voltage-gated calcium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CABP1 calcium binding protein 1 ISO RGD PMID:17960496 RGD:7207144 NCBI chr14:40,563,302...40,587,975
Ensembl chr14:40,563,159...40,587,970 		JBrowse link
G CACNB3 calcium voltage-gated channel auxiliary subunit beta 3 ISO RGD PMID:15024042 RGD:13514097 NCBI chr 5:14,875,524...14,888,224
Ensembl chr 5:14,874,465...14,888,223 		JBrowse link
G CBARP CACN subunit beta associated regulatory protein ISO RGD PMID:24751537 RGD:10047103 NCBI chr 2:77,220,790...77,230,418
Ensembl chr 2:77,220,972...77,230,058 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 ISO RGD PMID:26584289 RGD:155804278 NCBI chr 1:58,482,046...58,548,087
Ensembl chr 1:58,481,956...58,548,057 		JBrowse link
G OPRL1 opioid related nociceptin receptor 1 ISO RGD PMID:15937148 RGD:9835002 NCBI chr17:62,905,700...62,913,018
Ensembl chr17:62,905,082...62,913,754 		JBrowse link
negative regulation of voltage-gated potassium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 ISO RGD PMID:14679187 PMID:21943416 PMID:21943417 RGD:12910700 RGD:7242916 RGD:7243967 NCBI chr13:198,051,281...198,059,444
Ensembl chr13:198,051,282...198,059,296 		JBrowse link
G KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 ISO RGD PMID:14679187 PMID:19219384 PMID:21943416 RGD:7242916 RGD:7243947 RGD:7243967 NCBI chr13:197,979,749...197,980,974
Ensembl chr13:197,980,145...197,980,516 		JBrowse link
G KCNE3 potassium voltage-gated channel subfamily E regulatory subunit 3 ISO RGD PMID:14679187 RGD:7243967 NCBI chr 9:8,810,716...8,822,191
Ensembl chr 9:8,810,720...8,822,494 		JBrowse link
negative regulation of zinc ion transmembrane import term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC30A1 solute carrier family 30 member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:131,633,586...131,636,934
Ensembl chr 9:131,633,585...131,640,672 		JBrowse link
negative regulation of zinc ion transmembrane transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PIK3C2A phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha acts_upstream_of_or_within ISO (PMID:23823722) MGI PMID:23823722 NCBI chr 2:41,829,969...42,024,062
Ensembl chr 2:41,829,916...42,024,362 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17813
    cellular process 16883
      transmembrane transport 1532
        monoatomic ion transmembrane transport 947
          negative regulation of monoatomic ion transmembrane transport 73
            negative regulation of cation transmembrane transport 66
              negative regulation of calcium ion transmembrane transport + 34
              negative regulation of cation channel activity + 13
              negative regulation of copper ion transmembrane transport 0
              negative regulation of cytochrome-c oxidase activity 0
              negative regulation of iron ion transmembrane transport + 4
              negative regulation of oxidative phosphorylation uncoupler activity 0
              negative regulation of potassium ion transmembrane transport + 23
              negative regulation of sodium ion transmembrane transport + 7
              negative regulation of synaptic vesicle lumen acidification 0
              negative regulation of zinc ion transmembrane transport + 2
Path 2
Term Annotations click to browse term
  biological_process 17813
    localization 5385
      establishment of localization 4687
        transport 4381
          regulation of transport 1793
            regulation of transmembrane transport 417
              negative regulation of transmembrane transport 119
                negative regulation of monoatomic ion transmembrane transport 73
                  negative regulation of cation transmembrane transport 66
                    negative regulation of calcium ion transmembrane transport + 34
                    negative regulation of cation channel activity + 13
                    negative regulation of copper ion transmembrane transport 0
                    negative regulation of cytochrome-c oxidase activity 0
                    negative regulation of iron ion transmembrane transport + 4
                    negative regulation of oxidative phosphorylation uncoupler activity 0
                    negative regulation of potassium ion transmembrane transport + 23
                    negative regulation of sodium ion transmembrane transport + 7
                    negative regulation of synaptic vesicle lumen acidification 0
                    negative regulation of zinc ion transmembrane transport + 2
paths to the root