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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of spontaneous neurotransmitter secretion
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Accession:GO:1904050 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of spontaneous neurotransmitter secretion.
Comment:An example of this is PARK2 / parkin in human (O60260) in PMID:22314364 (inferred from mutant phenotype).
Synonyms:exact_synonym: positive regulation of stimulus-independent neurotransmitter secretion;   up regulation of spontaneous neurotransmitter secretion;   up regulation of stimulus-independent neurotransmitter secretion;   upregulation of spontaneous neurotransmitter secretion;   upregulation of stimulus-independent neurotransmitter secretion
 narrow_synonym: activation of spontaneous neurotransmitter secretion;   activation of stimulus-independent neurotransmitter secretion


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positive regulation of spontaneous neurotransmitter secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Stx1b syntaxin 1B IMP (MGI:5603022|PMID:24587181) ParkinsonsUK-UCL PMID:24587181 MGI:5603022 NCBI chr 7:127,803,900...127,824,531
Ensembl chr 7:127,803,900...127,824,549
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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23386
    signaling 6935
      positive regulation of signaling 1955
        positive regulation of synaptic transmission 335
          positive regulation of neurotransmitter secretion 20
            positive regulation of spontaneous neurotransmitter secretion 1
Path 2
Term Annotations click to browse term
  biological_process 23386
    cellular process 17420
      cell communication 7016
        cell-cell signaling 1751
          synaptic signaling 937
            trans-synaptic signaling 905
              anterograde trans-synaptic signaling 896
                chemical synaptic transmission 896
                  neurotransmitter secretion 191
                    regulation of neurotransmitter secretion 128
                      positive regulation of neurotransmitter secretion 20
                        positive regulation of spontaneous neurotransmitter secretion 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.