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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of spontaneous neurotransmitter secretion
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Accession:GO:1904048 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of spontaneous neurotransmitter secretion.
Comment:An example of this is PARK2 / parkin in human (O60260) in PMID:22314364 (inferred from mutant phenotype).
Synonyms:exact_synonym: regulation of stimulus-independent neurotransmitter secretion


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negative regulation of spontaneous neurotransmitter secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PPP1R9A protein phosphatase 1 regulatory subunit 9A IEA Ensembl GO_REF:0000107 NCBI chr 7:94,907,202...95,296,415
Ensembl chr 7:94,907,202...95,296,415
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase IMP (PMID:22314364) ParkinsonsUK-UCL PMID:22314364 NCBI chr 6:161,347,417...162,727,802
Ensembl chr 6:161,347,417...162,727,771
Ensembl chr 6:161,347,417...162,727,771
JBrowse link
positive regulation of spontaneous neurotransmitter secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G STX1B syntaxin 1B IEA Ensembl GO_REF:0000107 NCBI chr16:30,989,256...31,010,638
Ensembl chr16:30,989,256...31,010,638
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18673
    biological regulation 13311
      regulation of biological quality 4605
        regulation of neurotransmitter levels 285
          regulation of neurotransmitter secretion 137
            regulation of spontaneous neurotransmitter secretion 3
              negative regulation of spontaneous neurotransmitter secretion 2
              positive regulation of spontaneous neurotransmitter secretion 1
Path 2
Term Annotations click to browse term
  biological_process 18673
    cellular process 17693
      cell communication 7247
        cell-cell signaling 2065
          synaptic signaling 996
            trans-synaptic signaling 968
              anterograde trans-synaptic signaling 959
                chemical synaptic transmission 959
                  neurotransmitter secretion 218
                    regulation of neurotransmitter secretion 137
                      regulation of spontaneous neurotransmitter secretion 3
                        negative regulation of spontaneous neurotransmitter secretion 2
                        positive regulation of spontaneous neurotransmitter secretion 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.