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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of spontaneous neurotransmitter secretion
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Accession:GO:1904048 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of spontaneous neurotransmitter secretion.
Comment:An example of this is PARK2 / parkin in human (O60260) in PMID:22314364 (inferred from mutant phenotype).
Synonyms:exact_synonym: regulation of stimulus-independent neurotransmitter secretion


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negative regulation of spontaneous neurotransmitter secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppp1r9a protein phosphatase 1 regulatory subunit 9A ISO RGD PMID:16899074 RGD:10002752 NCBI chrNW_004955432:11,607,269...11,891,568
Ensembl chrNW_004955432:11,608,382...11,886,044
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G Prkn parkin RBR E3 ubiquitin protein ligase ISO (PMID:22314364) ParkinsonsUK-UCL PMID:22314364 NCBI chrNW_004955439:18,664,230...19,953,358
Ensembl chrNW_004955439:18,664,379...19,951,152
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positive regulation of spontaneous neurotransmitter secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Stx1b syntaxin 1B ISO (MGI:5603022|PMID:24587181) ParkinsonsUK-UCL PMID:24587181 MGI:5603022 NCBI chrNW_004955493:7,838,684...7,857,700
Ensembl chrNW_004955493:7,838,684...7,857,700
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11893
    biological regulation 8726
      regulation of biological quality 3359
        regulation of neurotransmitter levels 221
          regulation of neurotransmitter secretion 119
            regulation of spontaneous neurotransmitter secretion 3
              negative regulation of spontaneous neurotransmitter secretion 2
              positive regulation of spontaneous neurotransmitter secretion 1
Path 2
Term Annotations click to browse term
  biological_process 11893
    cellular process 11099
      cell communication 4210
        cell-cell signaling 1339
          synaptic signaling 654
            trans-synaptic signaling 634
              anterograde trans-synaptic signaling 627
                chemical synaptic transmission 627
                  neurotransmitter secretion 168
                    regulation of neurotransmitter secretion 119
                      regulation of spontaneous neurotransmitter secretion 3
                        negative regulation of spontaneous neurotransmitter secretion 2
                        positive regulation of spontaneous neurotransmitter secretion 1
paths to the root