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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of protein targeting to mitochondrion
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Accession:GO:1903955 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of protein targeting to mitochondrion.
Comment:An example of this is PINK1 in human (UniProt symbol Q9BXM7) in PMID:24270810 inferred from mutant phenotype.
Synonyms:exact_synonym: positive regulation of protein import into mitochondrion;   positive regulation of protein targeting to mitochondria;   positive regulation of protein-mitochondrial targeting;   up regulation of protein import into mitochondrion;   up regulation of protein targeting to mitochondria;   up regulation of protein targeting to mitochondrion;   up regulation of protein-mitochondrial targeting;   upregulation of protein import into mitochondrion;   upregulation of protein targeting to mitochondria;   upregulation of protein targeting to mitochondrion;   upregulation of protein-mitochondrial targeting
 narrow_synonym: activation of protein import into mitochondrion;   activation of protein targeting to mitochondria;   activation of protein targeting to mitochondrion;   activation of protein-mitochondrial targeting
 related_synonym: activation of mitochondrial protein import;   activation of mitochondrial translocation;   positive regulation of mitochondrial protein import;   positive regulation of mitochondrial translocation;   up regulation of mitochondrial protein import;   up regulation of mitochondrial translocation;   upregulation of mitochondrial protein import;   upregulation of mitochondrial translocation


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positive regulation of protein targeting to mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABLIM3 actin binding LIM protein family member 3 involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr 4:59,688,779...59,798,456
Ensembl chr 4:59,690,735...59,798,383 		JBrowse link
G ADCY10 adenylate cyclase 10 ISO RGD PMID:22106416 RGD:329337361 NCBI chr 7:30,576,445...30,660,926
Ensembl chr 7:30,577,591...30,660,926 		JBrowse link
G ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr20:40,178,560...40,230,870
Ensembl chr20:40,179,168...40,230,880 		JBrowse link
G ATG13 autophagy related 13 involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr18:42,834,538...42,886,873
Ensembl chr18:42,836,755...42,886,855 		JBrowse link
G BAP1 BRCA1 associated protein 1 involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr20:37,355,499...37,364,298
Ensembl chr20:37,355,494...37,511,125 		JBrowse link
G CSNK2A2 casein kinase 2 alpha 2 involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr 2:58,361,328...58,441,701
Ensembl chr 2:58,360,838...58,432,371 		JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:50,187,579...50,417,188
Ensembl chr15:50,189,240...50,417,195 		JBrowse link
G FZD5 frizzled class receptor 5 involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr37:16,123,788...16,126,634
Ensembl chr37:16,123,798...16,125,567 		JBrowse link
G GSK3A glycogen synthase kinase 3 alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:112,129,116...112,138,714
Ensembl chr 1:112,103,825...112,138,559 		JBrowse link
G HPS4 HPS4 biogenesis of lysosomal organelles complex 3 subunit 2 involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr26:20,131,658...20,157,532
Ensembl chr26:19,933,281...20,157,058 		JBrowse link
G HTRA2 HtrA serine peptidase 2 involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr17:48,610,408...48,613,399
Ensembl chr17:48,610,408...48,613,399 		JBrowse link
G HUWE1 HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr  X:45,234,666...45,409,641
Ensembl chr  X:45,234,322...45,410,043 		JBrowse link
G LEPROT leptin receptor overlapping transcript involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr 5:44,859,886...44,877,144
Ensembl chr 5:44,845,581...44,877,144 		JBrowse link
G LOC474850 heat shock 70 kDa protein 1-like involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:1,281,164...1,285,010
Ensembl chr12:1,281,472...1,285,440 		JBrowse link
G MICALL2 MICAL like 2 involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr 6:15,503,489...15,513,492
Ensembl chr 6:15,502,998...15,513,509 		JBrowse link
G NPEPPS aminopeptidase puromycin sensitive involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr 9:23,866,977...23,971,930
Ensembl chr 9:23,866,990...23,972,231 		JBrowse link
G PINK1 PTEN induced kinase 1 involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr 2:78,276,091...78,293,761
Ensembl chr 2:78,277,077...78,294,123 		JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:68,579,061...68,614,548
Ensembl chr 4:68,579,037...68,611,841 		JBrowse link
G PTPN5 protein tyrosine phosphatase non-receptor type 5 ISO RGD PMID:19625523 RGD:9835004 NCBI chr21:41,097,563...41,154,247
Ensembl chr21:41,097,569...41,136,706 		JBrowse link
G RAC2 Rac family small GTPase 2 involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr10:27,295,597...27,311,864
Ensembl chr10:27,295,640...27,311,397 		JBrowse link
G RHOU ras homolog family member U involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr 4:10,395,033...10,406,239
Ensembl chr 4:10,396,111...10,406,244 		JBrowse link
G RNF31 ring finger protein 31 involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr 8:4,141,501...4,151,999 JBrowse link
G SAE1 SUMO1 activating enzyme subunit 1 involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr 1:108,757,543...108,864,763
Ensembl chr 1:108,749,061...108,859,797 		JBrowse link
G SH3GLB1 SH3 domain containing GRB2 like, endophilin B1 involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr 6:61,439,414...61,471,414
Ensembl chr 6:61,439,415...61,462,087 		JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr10:23,451,923...23,532,765
Ensembl chr10:23,452,561...23,518,689
Ensembl chr10:23,452,561...23,518,689 		JBrowse link
G TOMM7 translocase of outer mitochondrial membrane 7 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr14:36,523,707...36,532,180
Ensembl chr14:36,523,707...36,532,291 		JBrowse link
G TOMM70 translocase of outer mitochondrial membrane 70 ISO RGD PMID:11956321 RGD:1303951 NCBI chr33:6,976,322...7,009,618
Ensembl chr33:6,976,934...7,009,594 		JBrowse link
G UBE2D3 ubiquitin conjugating enzyme E2 D3 involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr32:24,190,897...24,221,627 JBrowse link
G UBE2J2 ubiquitin conjugating enzyme E2 J2 involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr 5:56,440,394...56,455,491
Ensembl chr 5:56,441,821...56,455,460 		JBrowse link
G UBE2L3 ubiquitin conjugating enzyme E2 L3 involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr26:30,835,222...30,899,842
Ensembl chr26:30,823,209...30,898,324 		JBrowse link
G UBL4B ubiquitin like 4B involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr 6:41,859,051...41,859,770
Ensembl chr 6:41,858,083...41,860,425 		JBrowse link
G UBL5 ubiquitin like 5 involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr20:51,174,741...51,176,401
Ensembl chr20:51,174,741...51,176,292 		JBrowse link
G USP36 ubiquitin specific peptidase 36 involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr 9:2,547,316...2,587,360
Ensembl chr 9:2,550,452...2,585,108 		JBrowse link
G VPS11 VPS11 core subunit of CORVET and HOPS complexes involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr 5:14,776,975...14,786,736
Ensembl chr 5:14,776,976...14,786,692 		JBrowse link
positive regulation of protein insertion into mitochondrial outer membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDCD5 programmed cell death 5 involved_in ISO (PMID:16374546) UniProt PMID:16374546 NCBI chr 1:119,379,427...119,384,664
Ensembl chr 1:119,379,431...119,384,550 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17917
    localization 5609
      establishment of localization 4902
        establishment of protein localization 1713
          protein targeting 329
            protein targeting to mitochondrion 106
              positive regulation of protein targeting to mitochondrion 35
                positive regulation of protein insertion into mitochondrial outer membrane 1
Path 2
Term Annotations click to browse term
  biological_process 17917
    localization 5609
      macromolecule localization 3127
        cellular macromolecule localization 2660
          protein localization 2648
            protein localization to organelle 1073
              protein localization to mitochondrion 139
                establishment of protein localization to mitochondrion 129
                  protein targeting to mitochondrion 106
                    regulation of protein targeting to mitochondrion 46
                      positive regulation of protein targeting to mitochondrion 35
                        positive regulation of protein insertion into mitochondrial outer membrane 1
paths to the root