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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of protein targeting to mitochondrion
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Accession:GO:1903955 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of protein targeting to mitochondrion.
Comment:An example of this is PINK1 in human (UniProt symbol Q9BXM7) in PMID:24270810 inferred from mutant phenotype.
Synonyms:exact_synonym: positive regulation of protein import into mitochondrion;   positive regulation of protein targeting to mitochondria;   positive regulation of protein-mitochondrial targeting;   up regulation of protein import into mitochondrion;   up regulation of protein targeting to mitochondria;   up regulation of protein targeting to mitochondrion;   up regulation of protein-mitochondrial targeting;   upregulation of protein import into mitochondrion;   upregulation of protein targeting to mitochondria;   upregulation of protein targeting to mitochondrion;   upregulation of protein-mitochondrial targeting
 narrow_synonym: activation of protein import into mitochondrion;   activation of protein targeting to mitochondria;   activation of protein targeting to mitochondrion;   activation of protein-mitochondrial targeting
 related_synonym: activation of mitochondrial protein import;   activation of mitochondrial translocation;   positive regulation of mitochondrial protein import;   positive regulation of mitochondrial translocation;   up regulation of mitochondrial protein import;   up regulation of mitochondrial translocation;   upregulation of mitochondrial protein import;   upregulation of mitochondrial translocation


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positive regulation of protein targeting to mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ablim3 actin binding LIM protein family, member 3 involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr18:55,256,135...55,376,629
Ensembl chr18:55,257,583...55,376,380
JBrowse link
G Arih2 ariadne RBR E3 ubiquitin protein ligase 2 involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr 8:109,296,738...109,355,909
Ensembl chr 8:109,296,738...109,355,852
JBrowse link
G Atg13 autophagy related 13 involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr 3:77,647,069...77,681,028
Ensembl chr 3:77,645,790...77,681,043
JBrowse link
G Bap1 Brca1 associated protein 1 involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr16:6,446,709...6,455,535
Ensembl chr16:6,446,709...6,455,535
JBrowse link
G Csnk2a2 casein kinase 2 alpha 2 involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr19:9,556,443...9,596,080
Ensembl chr19:9,556,260...9,596,080
JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 involved_in ISO (PMID:24912190) RGD PMID:24912190 NCBI chr 2:170,150,552...170,310,698
Ensembl chr 2:170,149,694...170,309,941
JBrowse link
G Fzd5 frizzled class receptor 5 involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr 9:66,117,370...66,119,127
Ensembl chr 9:66,113,112...66,121,457
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in ISO (PMID:24912190) RGD PMID:24912190 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802
JBrowse link
G Hps4 HPS4, biogenesis of lysosomal organelles complex 3 subunit 2 involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr12:44,264,037...44,294,791
Ensembl chr12:44,264,037...44,294,632
JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like involved_in ISO (PMID:24270810) RGD PMID:24270810 NCBI chr20:3,848,843...3,855,571
Ensembl chr20:3,848,843...3,855,571
JBrowse link
G Htra2 HtrA serine peptidase 2 involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr 4:115,556,914...115,560,202
Ensembl chr 4:115,556,916...115,560,095
JBrowse link
G Huwe1 HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr  X:20,871,278...21,001,378
Ensembl chr  X:20,873,795...21,001,262
JBrowse link
G Leprot leptin receptor overlapping transcript involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr 5:116,289,843...116,301,951
Ensembl chr 5:116,289,822...116,301,988
JBrowse link
G Micall2 MICAL-like 2 involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr12:14,899,151...14,927,949
Ensembl chr12:14,899,157...14,927,946
JBrowse link
G Npepps aminopeptidase puromycin sensitive involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr10:82,191,454...82,273,967
Ensembl chr10:82,191,456...82,273,967
JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 involved_in ISO (MGI:6120139|PMID:23283301) RGD PMID:23283301 MGI:6120139 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
JBrowse link
G Ptpn5 protein tyrosine phosphatase, non-receptor type 5 IMP RGD PMID:19625523 RGD:9835004 NCBI chr 1:97,620,638...97,681,186
Ensembl chr 1:97,620,642...97,679,882
JBrowse link
G Rac2 Rac family small GTPase 2 involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr 7:110,101,344...110,128,718
Ensembl chr 7:110,116,260...110,128,720
JBrowse link
G Rhou ras homolog family member U involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr19:51,641,408...51,651,249 JBrowse link
G Rnf31 ring finger protein 31 involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr15:29,083,047...29,095,328
Ensembl chr15:29,083,631...29,101,915
JBrowse link
G Sae1 SUMO1 activating enzyme subunit 1 involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr 1:77,030,961...77,086,937
Ensembl chr 1:77,030,965...77,086,986
JBrowse link
G Sh3glb1 SH3 domain -containing GRB2-like endophilin B1 involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr 2:233,750,838...233,784,817
Ensembl chr 2:233,750,838...233,784,784
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848
JBrowse link
G Tomm7 translocase of outer mitochondrial membrane 7 involved_in ISO (PMID:24270810) RGD PMID:24270810 NCBI chr 4:11,305,122...11,311,963
Ensembl chr 4:11,305,110...11,311,962
JBrowse link
G Ube2d3 ubiquitin-conjugating enzyme E2D 3 involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr 2:223,868,397...223,899,606
Ensembl chr 2:223,868,730...223,898,081
JBrowse link
G Ube2j2 ubiquitin-conjugating enzyme E2, J2 involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr 5:166,533,374...166,547,811
Ensembl chr 5:166,533,418...166,547,804
JBrowse link
G Ube2l3 ubiquitin-conjugating enzyme E2L 3 involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr11:83,797,722...83,838,862
Ensembl chr11:83,797,722...83,838,862
JBrowse link
G Ubl4b ubiquitin-like 4B involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr 2:195,192,476...195,193,830 JBrowse link
G Ubl5 ubiquitin-like 5 involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr 8:19,183,437...19,185,223
Ensembl chr 8:19,181,615...19,185,217
JBrowse link
G Usp36 ubiquitin specific peptidase 36 involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr10:103,497,349...103,528,877
Ensembl chr10:103,497,349...103,528,877
JBrowse link
G Vps11 VPS11 core subunit of CORVET and HOPS complexes involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr 8:44,683,768...44,698,572
Ensembl chr 8:44,684,127...44,698,568
JBrowse link
positive regulation of protein insertion into mitochondrial outer membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdcd5 programmed cell death 5 involved_in ISO (PMID:16374546) RGD PMID:16374546 NCBI chr 1:88,305,869...88,311,200
Ensembl chr 1:88,305,869...88,311,200
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    positive regulation of biological process 6575
      positive regulation of cellular process 6048
        positive regulation of establishment of protein localization to mitochondrion 35
          positive regulation of protein targeting to mitochondrion 33
            positive regulation of protein insertion into mitochondrial outer membrane 1
Path 2
Term Annotations click to browse term
  biological_process 19492
    localization 6447
      macromolecule localization 3001
        protein localization 2559
          establishment of protein localization 1696
            protein transport 1571
              intracellular protein transport 904
                protein targeting 316
                  protein targeting to mitochondrion 103
                    regulation of protein targeting to mitochondrion 45
                      positive regulation of protein targeting to mitochondrion 33
                        positive regulation of protein insertion into mitochondrial outer membrane 1
paths to the root