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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of viral life cycle
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Accession:GO:1903901 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of viral life cycle.
Synonyms:exact_synonym: down regulation of viral life cycle;   downregulation of viral life cycle
 narrow_synonym: down regulation of viral assembly, maturation, egress, and release;   downregulation of viral assembly, maturation, egress, and release;   inhibition of viral assembly, maturation, egress, and release;   inhibition of viral life cycle;   negative regulation of viral assembly, maturation, egress, and release
 related_synonym: down regulation of lytic viral life cycle;   down regulation of viral infectious cycle;   down regulation of viral replication;   downregulation of lytic viral life cycle;   downregulation of viral infectious cycle;   downregulation of viral replication;   inhibition of lytic viral life cycle;   inhibition of viral infectious cycle;   inhibition of viral replication;   negative regulation of lytic viral life cycle;   negative regulation of viral infectious cycle;   negative regulation of viral replication



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negative regulation of viral life cycle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ark2n arkadia (RNF111) N-terminal like PKA signaling regulator 2N involved_in ISO (PMID:31341047) RGD PMID:31341047 NCBI chr18:71,155,956...71,243,655
Ensembl chr18:71,157,700...71,243,482
JBrowse link
G Csnk2b casein kinase 2 beta involved_in IEA
ISO
GO_REF:0000107
(PMID:31341047)
Ensembl
RGD
PMID:31341047 GO_REF:0000107 NCBI chr20:3,700,363...3,705,331
Ensembl chr20:3,698,733...3,707,133
JBrowse link
G Hmox1 heme oxygenase 1 involved_in ISO (PMID:25086213) RGD PMID:25086213 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Ppia peptidylprolyl isomerase A involved_in ISO (PMID:19207730), (PMID:22347431) RGD PMID:19207730 PMID:22347431 NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601
JBrowse link
G Samhd1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 involved_in ISO (PMID:25106914) RGD PMID:25106914 NCBI chr 3:145,761,549...145,794,420
Ensembl chr 3:145,761,558...145,794,386
JBrowse link
negative regulation of fusion of virus membrane with host plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ch25h cholesterol 25-hydroxylase involved_in ISO
ISS
(PMID:32944968), (PMID:33239446)
GO_REF:0000024
RGD
UniProt
PMID:32944968 PMID:33239446 GO_REF:0000024 NCBI chr 1:232,014,877...232,016,195
Ensembl chr 1:232,014,880...232,016,195
JBrowse link
negative regulation of intracellular transport of viral material term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bst2 bone marrow stromal cell antigen 2 involved_in ISO
ISS
(PMID:19036818), (PMID:20686043), (PMID:20943977)
(MGI:5437405|PMID:22284121), (MGI:5437427|PMID:20686043), (MGI:5448513|PMID:21919738)
GO_REF:0000024
RGD
UniProt
PMID:19036818 PMID:20686043 PMID:20943977 PMID:21919738 PMID:22284121 GO_REF:0000024 MGI:5437405 MGI:5437427 MGI:5448513 NCBI chr16:18,216,605...18,220,979
Ensembl chr16:18,217,407...18,220,979
JBrowse link
G Mx2 MX dynamin like GTPase 2 involved_in ISO (PMID:20167191) RGD PMID:20167191 NCBI chr11:36,905,698...36,936,308
Ensembl chr11:36,906,111...36,930,342
JBrowse link
G Trim15 tripartite motif containing 15 involved_in ISO (PMID:18248090) RGD PMID:18248090 NCBI chr20:1,700,905...1,710,249
Ensembl chr20:1,700,905...1,710,249
JBrowse link
negative regulation of viral entry into host cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apcs amyloid P component, serum involved_in IEA
ISO
GO_REF:0000107
(PMID:23544079)
Ensembl
RGD
PMID:23544079 GO_REF:0000107 NCBI chr13:85,373,219...85,374,195
Ensembl chr13:85,373,220...85,374,298
JBrowse link
G Cd74 CD74 molecule involved_in ISO (PMID:32855215) RGD PMID:32855215 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003
JBrowse link
G Ciita class II, major histocompatibility complex, transactivator involved_in ISO (PMID:32855215) RGD PMID:32855215 NCBI chr10:5,139,947...5,187,493
Ensembl chr10:5,140,178...5,187,440
JBrowse link
G ENSRNOG00000068074 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr 4:59,549,152...59,549,829 JBrowse link
G ENSRNOG00000070481 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr 4:30,960,845...30,961,834 JBrowse link
G Fcnb ficolin B involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 3:11,393,713...11,402,198
Ensembl chr 3:11,393,739...11,402,151
JBrowse link
G Gsn gelsolin involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402
JBrowse link
G Ifitm1 interferon induced transmembrane protein 1 involved_in
acts_upstream_of_or_within
ISO
IBA
(MGI:5437420|PMID:21253575)
(PMID:25738301)
GO_REF:0000033
(PMID:21253575), (PMID:23358889), (PMID:26354436)
RGD
GO_Central
PMID:21253575 PMID:23358889 PMID:25738301 PMID:26354436 GO_REF:0000033 MGI:5437420 NCBI chr 1:196,067,163...196,069,169
Ensembl chr 1:196,067,963...196,069,169
JBrowse link
G Ifitm2 interferon induced transmembrane protein 2 involved_in ISO
IBA
(MGI:5437420|PMID:21253575)
GO_REF:0000033
(PMID:21253575), (PMID:23358889), (PMID:26354436), (PMID:33563656)
RGD
GO_Central
PMID:21253575 PMID:23358889 PMID:26354436 PMID:33563656 GO_REF:0000033 MGI:5437420 NCBI chr 1:196,051,539...196,052,719
Ensembl chr 1:196,051,537...196,052,741
JBrowse link
G Ifitm2-ps2 interferon induced transmembrane protein 2, pseudogene 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:68,187,131...68,187,808
Ensembl chr13:68,187,366...68,187,854
JBrowse link
G Ifitm3 interferon induced transmembrane protein 3 involved_in ISO
IBA
ISS
(MGI:5437420|PMID:21253575)
GO_REF:0000033
(PMID:20943977), (PMID:21253575), (PMID:23358889), (PMID:26354436)
GO_REF:0000024
RGD
GO_Central
UniProt
PMID:20943977 PMID:21253575 PMID:23358889 PMID:26354436 GO_REF:0000024 GO_REF:0000033 MGI:5437420 NCBI chr 1:196,111,026...196,112,135
Ensembl chr 1:196,111,043...196,112,203
JBrowse link
G Ifitm3-ps1 interferon induced transmembrane protein3, pseudogene 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:61,233,269...61,233,688
Ensembl chr14:61,233,269...61,233,688
JBrowse link
G Ifitm6 interferon induced transmembrane protein 6 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:196,117,043...196,118,315
Ensembl chr 1:196,117,049...196,118,386
JBrowse link
G Ifitm7 interferon induced transmembrane protein 7 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr11:33,137,146...33,137,562
Ensembl chr11:33,137,146...33,138,061
JBrowse link
G Lrrc15 leucine rich repeat containing 15 involved_in ISO
IEA
(PMID:36228039), (PMID:36757924)
GO_REF:0000107
RGD
Ensembl
PMID:36228039 PMID:36757924 GO_REF:0000107 NCBI chr11:70,469,817...70,484,268
Ensembl chr11:70,469,804...70,484,267
JBrowse link
G Ly6e lymphocyte antigen 6 family member E involved_in ISO (PMID:32641482), (PMID:32704094)
(MGI:6448667|PMID:32704094)
RGD PMID:32641482 PMID:32704094 MGI:6448667 NCBI chr 7:106,935,530...106,939,689
Ensembl chr 7:106,935,761...106,939,689
JBrowse link
G Mid2 midline 2 involved_in ISO (PMID:18248090) RGD PMID:18248090 NCBI chr  X:104,354,692...104,456,757
Ensembl chr  X:104,355,316...104,453,473
JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease IMP RGD PMID:22850678 RGD:8693392 NCBI chr 8:11,618,876...11,680,451
Ensembl chr 8:11,632,354...11,678,279
JBrowse link
G Nbn nibrin IMP RGD PMID:22850678 RGD:8693392 NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150
JBrowse link
G Ptx3 pentraxin 3 involved_in ISO (PMID:23544079) RGD PMID:23544079 NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323
JBrowse link
G Rad50 RAD50 double strand break repair protein IMP RGD PMID:22850678 RGD:8693392 NCBI chr10:37,809,353...37,861,309
Ensembl chr10:37,808,726...37,861,396
JBrowse link
G Snx3 sorting nexin 3 involved_in ISO (PMID:18767904) RGD PMID:18767904 NCBI chr20:45,992,446...46,025,361
Ensembl chr20:45,992,720...46,025,379
JBrowse link
G Trim10 tripartite motif-containing 10 involved_in ISO (MGI:5545996|PMID:18248090) RGD PMID:18248090 MGI:5545996 NCBI chr20:1,689,554...1,698,948
Ensembl chr20:1,689,562...1,698,252
JBrowse link
G Trim11 tripartite motif-containing 11 involved_in ISO (PMID:18248090)
(MGI:5545996|PMID:18248090)
RGD PMID:18248090 MGI:5545996 NCBI chr10:43,758,299...43,771,138
Ensembl chr10:43,758,354...43,771,138
JBrowse link
G Trim25 tripartite motif-containing 25 involved_in ISO (MGI:5545996|PMID:18248090) RGD PMID:18248090 MGI:5545996 NCBI chr10:73,812,818...73,831,271
Ensembl chr10:73,812,818...73,831,257
JBrowse link
G Trim26 tripartite motif-containing 26 involved_in ISO
IEA
IBA
(PMID:18248090)
GO_REF:0000118
GO_REF:0000033
GO_REF:0000107
RGD
TreeGrafter
GO_Central
Ensembl
PMID:18248090 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr20:1,708,297...1,731,176
Ensembl chr20:1,709,788...1,731,120
JBrowse link
G Trim31 tripartite motif-containing 31 involved_in ISO
IBA
(PMID:18248090)
GO_REF:0000033
(MGI:5545996|PMID:18248090)
RGD
GO_Central
PMID:18248090 GO_REF:0000033 MGI:5545996 NCBI chr20:1,653,165...1,666,494
Ensembl chr20:1,653,165...1,666,494
JBrowse link
G Trim5 tripartite motif-containing 5 involved_in ISO (PMID:18248090) RGD PMID:18248090 NCBI chr 1:158,720,407...158,737,393
Ensembl chr 1:158,720,410...158,814,012
JBrowse link
G Trim56 tripartite motif containing 56 involved_in ISO (MGI:5545996|PMID:18248090) RGD PMID:18248090 MGI:5545996 NCBI chr12:19,544,913...19,567,324
Ensembl chr12:19,551,521...19,567,462
JBrowse link
G Trim59 tripartite motif-containing 59 involved_in ISO (MGI:5545996|PMID:18248090) RGD PMID:18248090 MGI:5545996 NCBI chr 2:153,269,210...153,281,185
Ensembl chr 2:153,268,584...153,281,031
JBrowse link
G Trim8 tripartite motif-containing 8 involved_in ISO (MGI:5545996|PMID:18248090) RGD PMID:18248090 MGI:5545996 NCBI chr 1:245,369,632...245,384,513
Ensembl chr 1:245,369,632...245,384,513
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    viral process 346
      viral life cycle 270
        negative regulation of viral life cycle 40
          negative regulation of intracellular transport of viral material 3
          negative regulation of viral budding via host ESCRT complex 0
          negative regulation of viral entry into host cell + 32
Path 2
Term Annotations click to browse term
  biological_process 20413
    biological regulation 13755
      regulation of biological process 13322
        regulation of viral process 177
          negative regulation of viral process 102
            negative regulation of viral life cycle 40
              negative regulation of intracellular transport of viral material 3
              negative regulation of viral budding via host ESCRT complex 0
              negative regulation of viral entry into host cell + 32
paths to the root