Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of PERK-mediated unfolded protein response
go back to main search page
Accession:GO:1903898 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of the PERK-mediated unfolded protein response.
Synonyms:exact_synonym: down regulation of PERK branch of UPR;   down regulation of PERK-mediated unfolded protein response;   down regulation of PKR-like ER kinase signal transduction;   down regulation of UPR signaling by PERK stress sensor;   down regulation of endoplasmic reticulum unfolded protein response; PERK signaling;   downregulation of PERK branch of UPR;   downregulation of PERK-mediated unfolded protein response;   downregulation of PKR-like ER kinase signal transduction;   downregulation of UPR signaling by PERK stress sensor;   downregulation of endoplasmic reticulum unfolded protein response; PERK signaling;   negative regulation of PERK branch of UPR;   negative regulation of PKR-like ER kinase signal transduction;   negative regulation of UPR signaling by PERK stress sensor;   negative regulation of endoplasmic reticulum unfolded protein response; PERK signaling
 narrow_synonym: inhibition of PERK branch of UPR;   inhibition of PERK-mediated unfolded protein response;   inhibition of PKR-like ER kinase signal transduction;   inhibition of UPR signaling by PERK stress sensor;   inhibition of endoplasmic reticulum unfolded protein response; PERK signaling
 related_synonym: down regulation of PERK signaling in response to endoplasmic reticulum stress;   downregulation of PERK signaling in response to endoplasmic reticulum stress;   inhibition of PERK signaling in response to endoplasmic reticulum stress;   negative regulation of EIF2AK3-mediated unfolded protein response;   negative regulation of PERK signaling in response to endoplasmic reticulum stress


show annotations for term's descendants           Sort by:
 
negative regulation of PERK-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca7 ATP-binding cassette, sub-family A (ABC1), member 7 involved_in IMP (MGI:5774886|PMID:27030769) ARUK-UCL PMID:27030769 MGI:5774886 NCBI chr10:79,996,453...80,015,572
Ensembl chr10:79,996,494...80,015,572
JBrowse link
G Nck1 non-catalytic region of tyrosine kinase adaptor protein 1 involved_in ISO
IBA
IGI
(MGI:6201960|PMID:21873635)
(MGI:5613478|PMID:14676213)
MGI
GO_Central
ParkinsonsUK-UCL
PMID:14676213 PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:5613478 MGI:6201960 NCBI chr 9:100,494,302...100,546,134
Ensembl chr 9:100,492,293...100,546,134
JBrowse link
G Nck2 non-catalytic region of tyrosine kinase adaptor protein 2 involved_in IGI
IBA
(MGI:5613478|PMID:14676213)
(MGI:6201960|PMID:21873635)
ParkinsonsUK-UCL
GO_Central
PMID:14676213 PMID:21873635 MGI:5613478 MGI:6201960 NCBI chr 1:43,445,483...43,570,518
Ensembl chr 1:43,444,579...43,570,515
JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 involved_in IMP
ISO
(MGI:5619464|PMID:21216966) ParkinsonsUK-UCL
MGI
PMID:21216966 GO_REF:0000096 MGI:4834177 MGI:5619464 NCBI chr 2:167,930,750...167,979,385
Ensembl chr 2:167,932,057...167,979,385
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28616
    cellular process 17619
      signal transduction 6515
        ER-nucleus signaling pathway 43
          PERK-mediated unfolded protein response 14
            negative regulation of PERK-mediated unfolded protein response 4
Path 2
Term Annotations click to browse term
  biological_process 28616
    response to stimulus 10451
      response to chemical 5497
        response to organic substance 4082
          response to topologically incorrect protein 143
            response to unfolded protein 121
              cellular response to unfolded protein 91
                endoplasmic reticulum unfolded protein response 70
                  regulation of endoplasmic reticulum unfolded protein response 24
                    negative regulation of endoplasmic reticulum unfolded protein response 12
                      negative regulation of PERK-mediated unfolded protein response 4
paths to the root