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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of PERK-mediated unfolded protein response
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Accession:GO:1903897 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the PERK-mediated unfolded protein response.
Synonyms:exact_synonym: regulation of PERK branch of UPR;   regulation of PKR-like ER kinase signal transduction;   regulation of UPR signaling by PERK stress sensor;   regulation of endoplasmic reticulum unfolded protein response; PERK signaling
 broad_synonym: regulation of PERK signal transduction pathway
 related_synonym: regulation of EIF2AK3-mediated unfolded protein response;   regulation of PERK signaling in response to endoplasmic reticulum stress


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negative regulation of PERK-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca7 ATP binding cassette subfamily A member 7 involved_in ISO (MGI:5774886|PMID:27030769) RGD PMID:27030769 MGI:5774886 NCBI chr 7:12,742,433...12,762,423
Ensembl chr 7:12,742,433...12,762,341
JBrowse link
G Nck1 NCK adaptor protein 1 involved_in ISO (PMID:14676213)
UniProtKB:O55033 (MGI:5613478|PMID:14676213)
RGD PMID:14676213 MGI:5613478 NCBI chr 8:108,787,797...108,847,779
Ensembl chr 8:108,787,798...108,847,779
JBrowse link
G Nck2 NCK adaptor protein 2 involved_in ISO UniProtKB:Q99M51 (MGI:5613478|PMID:14676213) RGD PMID:14676213 MGI:5613478 NCBI chr 9:50,246,767...50,373,307
Ensembl chr 9:50,247,692...50,373,284
JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 involved_in ISO (PMID:21216966)
(MGI:5619464|PMID:21216966)
RGD PMID:21216966 MGI:5619464 NCBI chr 3:164,665,462...164,711,936
Ensembl chr 3:164,665,532...164,711,848
JBrowse link
positive regulation of PERK-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agr2 anterior gradient 2, protein disulphide isomerase family member involved_in ISO (PMID:23220234) RGD PMID:23220234 NCBI chr 6:55,465,782...55,487,087
Ensembl chr 6:55,465,782...55,487,714
JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in ISS
ISO
GO_REF:0000024
(MGI:5648772|PMID:26015568)
UniProt
RGD
PMID:26015568 GO_REF:0000024 MGI:5648772 NCBI chr 9:100,829,593...100,840,498
Ensembl chr 9:100,829,552...100,840,504
JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISO (MGI:5619464|PMID:21216966) RGD PMID:21216966 MGI:5619464 NCBI chr18:63,415,298...63,489,240
Ensembl chr18:63,415,306...63,488,027
JBrowse link
G Tmem33 transmembrane protein 33 involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:26268696)
Ensembl
UniProt
RGD
PMID:26268696 GO_REF:0000024 GO_REF:0000107 NCBI chr14:42,537,352...42,559,580
Ensembl chr14:42,535,701...42,560,174
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19610
    cellular process 18463
      signal transduction 6949
        ER-nucleus signaling pathway 44
          PERK-mediated unfolded protein response 14
            regulation of PERK-mediated unfolded protein response 8
              negative regulation of PERK-mediated unfolded protein response 4
              positive regulation of PERK-mediated unfolded protein response 4
Path 2
Term Annotations click to browse term
  biological_process 19610
    response to stimulus 10427
      response to chemical 6228
        response to organic substance 3881
          response to topologically incorrect protein 145
            response to unfolded protein 121
              cellular response to unfolded protein 103
                endoplasmic reticulum unfolded protein response 75
                  regulation of endoplasmic reticulum unfolded protein response 26
                    regulation of PERK-mediated unfolded protein response 8
                      negative regulation of PERK-mediated unfolded protein response 4
                      positive regulation of PERK-mediated unfolded protein response 4
paths to the root