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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of IRE1-mediated unfolded protein response
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Accession:GO:1903895 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of the IRE1-mediated unfolded protein response.
Synonyms:exact_synonym: down regulation of IRE1 branch of UPR;   down regulation of IRE1-mediated unfolded protein response;   down regulation of UPR signaling by IRE1 stress sensor;   down regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling;   downregulation of IRE1 branch of UPR;   downregulation of IRE1-mediated unfolded protein response;   downregulation of UPR signaling by IRE1 stress sensor;   downregulation of endoplasmic reticulum unfolded protein response; IRE1 signaling;   negative regulation of IRE1 branch of UPR;   negative regulation of UPR signaling by IRE1 stress sensor;   negative regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling
 narrow_synonym: down regulation of IRE1alpha unfolded protein response;   down regulation of IRE1p unfolded protein response;   downregulation of IRE1alpha unfolded protein response;   downregulation of IRE1p unfolded protein response;   inhibition of IRE1 branch of UPR;   inhibition of IRE1-mediated unfolded protein response;   inhibition of IRE1alpha unfolded protein response;   inhibition of IRE1p unfolded protein response;   inhibition of UPR signaling by IRE1 stress sensor;   inhibition of endoplasmic reticulum unfolded protein response; IRE1 signaling;   negative regulation of IRE1alpha unfolded protein response;   negative regulation of IRE1p unfolded protein response
 related_synonym: down regulation of IRE1 signaling in response to endoplasmic reticulum stress;   down regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction;   downregulation of IRE1 signaling in response to endoplasmic reticulum stress;   downregulation of inositol-requiring transmembrane kinase/endonuclease signal transduction;   inhibition of IRE1 signaling in response to endoplasmic reticulum stress;   inhibition of inositol-requiring transmembrane kinase/endonuclease signal transduction;   negative regulation of ERN1-mediated unfolded protein response;   negative regulation of IRE1 signaling in response to endoplasmic reticulum stress;   negative regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction


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negative regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BFAR bifunctional apoptosis regulator involved_in IMP (PMID:21068390) ParkinsonsUK-UCL PMID:21068390 NCBI chr16:14,632,831...14,669,236
Ensembl chr16:14,632,931...14,669,236
JBrowse link
G DDRGK1 DDRGK domain containing 1 involved_in IDA (PMID:28128204), (PMID:32160526) UniProt PMID:28128204 PMID:32160526 NCBI chr20:3,190,350...3,204,682
Ensembl chr20:3,190,350...3,204,685
JBrowse link
G DNAJB9 DnaJ heat shock protein family (Hsp40) member B9 involved_in ISS UniProt GO_REF:0000024 NCBI chr 7:108,569,874...108,574,850
Ensembl chr 7:108,569,867...108,574,850
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 involved_in ISS UniProt GO_REF:0000024 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382
JBrowse link
G PDIA6 protein disulfide isomerase family A member 6 involved_in ISO (MGI:5571560|PMID:24508390) WB PMID:24508390 MGI:5571560 NCBI chr 2:10,783,391...10,837,712
Ensembl chr 2:10,783,391...10,837,977
JBrowse link
G UFL1 UFM1 specific ligase 1 involved_in IDA (PMID:32160526) UniProt PMID:32160526 NCBI chr 6:96,521,806...96,555,276
Ensembl chr 6:96,521,595...96,555,276
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18537
    cellular process 17456
      signal transduction 6274
        endoplasmic reticulum unfolded protein response 81
          IRE1-mediated unfolded protein response 21
            negative regulation of IRE1-mediated unfolded protein response 6
Path 2
Term Annotations click to browse term
  biological_process 18537
    response to stimulus 9790
      cellular response to stimulus 8118
        cellular response to chemical stimulus 3681
          cellular response to organic substance 3000
            cellular response to topologically incorrect protein 125
              cellular response to unfolded protein 105
                endoplasmic reticulum unfolded protein response 81
                  regulation of endoplasmic reticulum unfolded protein response 32
                    regulation of IRE1-mediated unfolded protein response 16
                      negative regulation of IRE1-mediated unfolded protein response 6
paths to the root