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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of IRE1-mediated unfolded protein response
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Accession:GO:1903895 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of the IRE1-mediated unfolded protein response.
Synonyms:exact_synonym: down regulation of IRE1 branch of UPR;   down regulation of IRE1-mediated unfolded protein response;   down regulation of UPR signaling by IRE1 stress sensor;   down regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling;   downregulation of IRE1 branch of UPR;   downregulation of IRE1-mediated unfolded protein response;   downregulation of UPR signaling by IRE1 stress sensor;   downregulation of endoplasmic reticulum unfolded protein response; IRE1 signaling;   negative regulation of IRE1 branch of UPR;   negative regulation of UPR signaling by IRE1 stress sensor;   negative regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling
 narrow_synonym: down regulation of IRE1alpha unfolded protein response;   down regulation of IRE1p unfolded protein response;   downregulation of IRE1alpha unfolded protein response;   downregulation of IRE1p unfolded protein response;   inhibition of IRE1 branch of UPR;   inhibition of IRE1-mediated unfolded protein response;   inhibition of IRE1alpha unfolded protein response;   inhibition of IRE1p unfolded protein response;   inhibition of UPR signaling by IRE1 stress sensor;   inhibition of endoplasmic reticulum unfolded protein response; IRE1 signaling;   negative regulation of IRE1alpha unfolded protein response;   negative regulation of IRE1p unfolded protein response
 related_synonym: down regulation of IRE1 signaling in response to endoplasmic reticulum stress;   down regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction;   downregulation of IRE1 signaling in response to endoplasmic reticulum stress;   downregulation of inositol-requiring transmembrane kinase/endonuclease signal transduction;   inhibition of IRE1 signaling in response to endoplasmic reticulum stress;   inhibition of inositol-requiring transmembrane kinase/endonuclease signal transduction;   negative regulation of ERN1-mediated unfolded protein response;   negative regulation of IRE1 signaling in response to endoplasmic reticulum stress;   negative regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction


show annotations for term's descendants           Sort by:
negative regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bfar bifunctional apoptosis regulator involved_in ISO (PMID:21068390) RGD PMID:21068390 NCBI chr10:1,552,019...1,585,040
Ensembl chr10:1,552,072...1,585,038 		JBrowse link
G Ddrgk1 DDRGK domain containing 1 involved_in ISO
IBA		 (PMID:28128204), (PMID:32160526)
(MGI:5912977|PMID:28128204)
GO_REF:0000033		 RGD
GO_Central		 PMID:28128204 PMID:32160526 GO_REF:0000033 MGI:5912977 NCBI chr 3:117,861,916...117,882,680
Ensembl chr 3:117,861,653...117,882,680 		JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Pdia6 protein disulfide isomerase family A, member 6 involved_in ISO (PMID:24508390) RGD PMID:24508390 NCBI chr 6:40,062,980...40,080,223
Ensembl chr 6:40,062,926...40,080,613 		JBrowse link
G Ufl1 Ufm1-specific ligase 1 involved_in ISO
ISS		 (PMID:32160526)
GO_REF:0000024		 RGD
UniProt		 PMID:32160526 GO_REF:0000024 NCBI chr 5:38,962,721...38,995,134
Ensembl chr 5:38,962,171...38,995,199 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    cellular process 18812
      signal transduction 7209
        endoplasmic reticulum unfolded protein response 77
          IRE1-mediated unfolded protein response 16
            negative regulation of IRE1-mediated unfolded protein response 6
Path 2
Term Annotations click to browse term
  biological_process 20413
    response to stimulus 10920
      cellular response to stimulus 9075
        cellular response to chemical stimulus 3328
          cellular response to organic substance 2496
            cellular response to topologically incorrect protein 109
              cellular response to unfolded protein 93
                endoplasmic reticulum unfolded protein response 77
                  regulation of endoplasmic reticulum unfolded protein response 27
                    regulation of IRE1-mediated unfolded protein response 10
                      negative regulation of IRE1-mediated unfolded protein response 6
paths to the root