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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of IRE1-mediated unfolded protein response
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Accession:GO:1903894 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the IRE1-mediated unfolded protein response.
Synonyms:exact_synonym: regulation of IRE1 branch of UPR;   regulation of UPR signaling by IRE1 stress sensor;   regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling
 narrow_synonym: regulation of IRE1alpha unfolded protein response;   regulation of IRE1p unfolded protein response
 broad_synonym: regulation of IRE1 signal transduction pathway
 related_synonym: regulation of ERN1-mediated unfolded protein response;   regulation of IRE1 signaling in response to endoplasmic reticulum stress;   regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction


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regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cops5 COP9 signalosome subunit 5 involved_in ISO (PMID:15234121) RGD PMID:15234121 NCBI chr 5:8,876,090...8,894,345
Ensembl chr 5:8,876,044...8,894,339
JBrowse link
G Ficd FIC domain protein adenylyltransferase involved_in ISO
ISS
(PMID:25601083)
GO_REF:0000024
RGD
UniProt
PMID:25601083 GO_REF:0000024 NCBI chr12:48,658,283...48,663,175
Ensembl chr12:48,658,283...48,663,143
JBrowse link
negative regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bfar bifunctional apoptosis regulator involved_in ISO (PMID:21068390) RGD PMID:21068390 NCBI chr10:1,464,783...1,497,653
Ensembl chr10:1,464,765...1,497,653
JBrowse link
G Ddrgk1 DDRGK domain containing 1 involved_in ISO (PMID:28128204), (PMID:32160526)
(MGI:5912977|PMID:28128204)
RGD PMID:28128204 PMID:32160526 MGI:5912977 NCBI chr 3:123,195,580...123,206,828
Ensembl chr 3:123,195,580...123,206,828
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 6:64,165,913...64,170,122
Ensembl chr 6:64,165,913...64,170,151
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Pdia6 protein disulfide isomerase family A, member 6 involved_in ISO (MGI:5571560|PMID:24508390) RGD PMID:24508390 MGI:5571560 NCBI chr 6:42,568,269...42,585,654
Ensembl chr 6:42,568,220...42,585,652
JBrowse link
G Ufl1 Ufm1-specific ligase 1 involved_in ISO
ISS
(PMID:32160526)
GO_REF:0000024
RGD
UniProt
PMID:32160526 GO_REF:0000024 NCBI chr 5:39,616,479...39,650,894
Ensembl chr 5:39,615,956...39,650,895
JBrowse link
positive regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agr2 anterior gradient 2, protein disulphide isomerase family member involved_in ISO (PMID:23220234) RGD PMID:23220234 NCBI chr 6:55,465,782...55,487,087
Ensembl chr 6:55,465,782...55,487,714
JBrowse link
G Tmem33 transmembrane protein 33 involved_in ISO
IEA
ISS
(PMID:26268696)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:26268696 GO_REF:0000024 GO_REF:0000107 NCBI chr14:42,537,352...42,559,580
Ensembl chr14:42,535,701...42,560,174
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19491
    cellular process 18343
      signal transduction 6881
        endoplasmic reticulum unfolded protein response 71
          IRE1-mediated unfolded protein response 15
            regulation of IRE1-mediated unfolded protein response 10
              negative regulation of IRE1-mediated unfolded protein response 6
              positive regulation of IRE1-mediated unfolded protein response 2
Path 2
Term Annotations click to browse term
  biological_process 19491
    response to stimulus 10357
      response to chemical 6186
        response to organic substance 3889
          response to topologically incorrect protein 142
            response to unfolded protein 120
              cellular response to unfolded protein 99
                endoplasmic reticulum unfolded protein response 71
                  regulation of endoplasmic reticulum unfolded protein response 26
                    regulation of IRE1-mediated unfolded protein response 10
                      negative regulation of IRE1-mediated unfolded protein response 6
                      positive regulation of IRE1-mediated unfolded protein response 2
paths to the root