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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of ATF6-mediated unfolded protein response
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Accession:GO:1903892 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of the ATF6-mediated unfolded protein response.
Synonyms:exact_synonym: down regulation of ATF6 branch of UPR;   down regulation of ATF6-mediated unfolded protein response;   down regulation of UPR signaling by ATF6 stress sensor;   down regulation of activating transcription factor 6 signaling in unfolded protein response;   down regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling;   downregulation of ATF6 branch of UPR;   downregulation of ATF6-mediated unfolded protein response;   downregulation of UPR signaling by ATF6 stress sensor;   downregulation of activating transcription factor 6 signaling in unfolded protein response;   downregulation of endoplasmic reticulum unfolded protein response; ATF6 signaling;   negative regulation of ATF6 branch of UPR;   negative regulation of UPR signaling by ATF6 stress sensor;   negative regulation of activating transcription factor 6 signaling in unfolded protein response;   negative regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling
 narrow_synonym: down regulation of ATF6-alpha UPR branch;   down regulation of ATF6-beta UPR branch;   downregulation of ATF6-alpha UPR branch;   downregulation of ATF6-beta UPR branch;   inhibition of ATF6 branch of UPR;   inhibition of ATF6-alpha UPR branch;   inhibition of ATF6-beta UPR branch;   inhibition of ATF6-mediated unfolded protein response;   inhibition of UPR signaling by ATF6 stress sensor;   inhibition of activating transcription factor 6 signaling in unfolded protein response;   inhibition of endoplasmic reticulum unfolded protein response; ATF6 signaling;   negative regulation of ATF6-alpha UPR branch;   negative regulation of ATF6-beta UPR branch
 related_synonym: down regulation of ATF6 signaling in response to endoplasmic reticulum stress;   downregulation of ATF6 signaling in response to endoplasmic reticulum stress;   inhibition of ATF6 signaling in response to endoplasmic reticulum stress;   negative regulation of ATF6 signaling in response to endoplasmic reticulum stress


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negative regulation of ATF6-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF6B activating transcription factor 6 beta involved_in ISO (PMID:9837962) UniProt PMID:9837962 NCBI chr 6:31,762,161...31,775,136
Ensembl chr 6:32,643,124...32,655,617
JBrowse link
G WFS1 wolframin ER transmembrane glycoprotein involved_in ISO PMID:20160352
(PMID:20160352)
ParkinsonsUK-UCL PMID:20160352 RGD:10047363 Ensembl chr 4:6,345,864...6,379,287 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12657
    cellular process 11790
      signal transduction 3927
        ER-nucleus signaling pathway 43
          ATF6-mediated unfolded protein response 3
            negative regulation of ATF6-mediated unfolded protein response 2
Path 2
Term Annotations click to browse term
  biological_process 12657
    response to stimulus 6825
      response to chemical 3970
        response to organic substance 3196
          response to topologically incorrect protein 96
            response to unfolded protein 80
              cellular response to unfolded protein 73
                endoplasmic reticulum unfolded protein response 61
                  regulation of endoplasmic reticulum unfolded protein response 24
                    negative regulation of endoplasmic reticulum unfolded protein response 12
                      negative regulation of ATF6-mediated unfolded protein response 2
paths to the root