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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of voltage-gated potassium channel activity
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Accession:GO:1903817 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated potassium channel activity.
Synonyms:exact_synonym: down regulation of voltage gated potassium channel activity;   down regulation of voltage-dependent potassium channel activity;   down regulation of voltage-gated potassium ion channel activity;   down regulation of voltage-sensitive potassium channel;   downregulation of voltage gated potassium channel activity;   downregulation of voltage-dependent potassium channel activity;   downregulation of voltage-gated potassium ion channel activity;   downregulation of voltage-sensitive potassium channel;   negative regulation of voltage-dependent potassium channel activity;   negative regulation of voltage-gated potassium ion channel activity;   negative regulation of voltage-sensitive potassium channel
 narrow_synonym: inhibition of voltage gated potassium channel activity;   inhibition of voltage-dependent potassium channel activity;   inhibition of voltage-gated potassium ion channel activity;   inhibition of voltage-sensitive potassium channel


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negative regulation of voltage-gated potassium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnab1 potassium voltage-gated channel subfamily A regulatory beta subunit 1 involved_in ISO (PMID:10585425) RGD PMID:10585425 NCBI chr 2:149,137,025...149,603,540 JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 IDA RGD PMID:14679187, PMID:21943416, PMID:21943417 RGD:7243967, RGD:7242916, RGD:12910700 NCBI chr11:31,580,951...31,594,116 JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 IDA RGD PMID:19219384, PMID:21943416, PMID:14679187 RGD:7243947, RGD:7242916, RGD:7243967 NCBI chr11:31,517,176...31,530,026 JBrowse link
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in IDA
ISO
(PMID:22987075) RGD PMID:22987075, PMID:14679187 RGD:7243967 NCBI chr 1:154,523,903...154,530,865 JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO (PMID:9305853) RGD PMID:9305853 NCBI chr 1:198,291,711...198,624,683 JBrowse link
negative regulation of delayed rectifier potassium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank3 ankyrin 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:5613458|PMID:23903368)
UniProt
RGD
PMID:23903368 GO_REF:0000024 MGI:5613458 NCBI chr20:18,602,267...19,225,831 JBrowse link
G Kcnab1 potassium voltage-gated channel subfamily A regulatory beta subunit 1 involved_in IDA
IBA
IMP
PMID:21873635 RGD
GO_Central
PMID:8183366, PMID:21873635, PMID:8799886 RGD:61642, RGD:13792537, RGD:9743956 NCBI chr 2:149,137,025...149,603,540 JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 involved_in IBA
IDA
ISO
PMID:21873635
PMID:19219384
(PMID:19219384)
RGD PMID:19219384, PMID:21873635, PMID:19219384 RGD:13792537, RGD:7243947 NCBI chr11:31,580,951...31,594,116 JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in IDA
IBA
ISO
PMID:19219384
PMID:21873635
(PMID:19219384)
RGD PMID:19219384, PMID:19219384, PMID:21873635 RGD:7243947, RGD:13792537 NCBI chr11:31,517,176...31,530,026 JBrowse link
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in IBA
IDA
ISO
PMID:21873635
PMID:12954870
(PMID:12954870)
RGD PMID:12954870, PMID:21873635, PMID:12954870 RGD:13792537, RGD:10047250 NCBI chr 1:154,523,903...154,530,865 JBrowse link
G Kcne4 potassium voltage-gated channel subfamily E regulatory subunit 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:80,243,429...80,251,533 JBrowse link
G Kcne5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:105,930,398...105,931,013 JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO (PMID:9305853) RGD PMID:9305853 NCBI chr 1:198,291,711...198,624,683 JBrowse link
G Kcnrg potassium channel regulator involved_in ISO
IBA
(PMID:19968958)
PMID:21873635
RGD PMID:19968958, PMID:21873635 RGD:13792537 NCBI chr15:35,774,492...35,778,818 JBrowse link
G Mtnr1b melatonin receptor 1B IDA RGD PMID:14962062 RGD:9588668 NCBI chr 8:12,638,219...12,652,737 JBrowse link
G Sumo1 small ubiquitin-like modifier 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:19223394)
UniProt
RGD
PMID:19223394 GO_REF:0000024 NCBI chr 9:61,078,790...61,108,697 JBrowse link
negative regulation of inward rectifier potassium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav1 caveolin 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:18923542)
Ensembl
RGD
PMID:18923542 GO_REF:0000107 NCBI chr 4:45,640,624...45,673,708 JBrowse link
G Snx27 sorting nexin 27 IDA RGD PMID:21422294 RGD:8554349 NCBI chr 2:182,135,904...182,218,906 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    negative regulation of biological process 5618
      negative regulation of transport 529
        negative regulation of transporter activity 91
          negative regulation of ion transmembrane transporter activity 82
            negative regulation of potassium ion transmembrane transporter activity 23
              negative regulation of voltage-gated potassium channel activity 13
                negative regulation of delayed rectifier potassium channel activity 11
                negative regulation of inward rectifier potassium channel activity 2
                negative regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization 0
                negative regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 0
Path 2
Term Annotations click to browse term
  biological_process 19492
    localization 6444
      establishment of localization 4863
        transport 4699
          ion transport 1638
            cation transport 1259
              metal ion transport 942
                potassium ion transport 253
                  regulation of potassium ion transport 115
                    regulation of potassium ion transmembrane transport 92
                      regulation of potassium ion transmembrane transporter activity 65
                        negative regulation of potassium ion transmembrane transporter activity 23
                          negative regulation of voltage-gated potassium channel activity 13
                            negative regulation of delayed rectifier potassium channel activity 11
                            negative regulation of inward rectifier potassium channel activity 2
                            negative regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization 0
                            negative regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 0
paths to the root