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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of miRNA maturation
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Accession:GO:1903799 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of maturation of miRNAs.
Synonyms:exact_synonym: down regulation of gene silencing by miRNA, production of miRNAs;   down regulation of miRNA processing;   down regulation of miRNA-mediated gene silencing, production of miRNAs;   down regulation of microRNA-mediated gene silencing, production of microRNAs;   down regulation of production of miRNAs involved in gene silencing by miRNA;   down regulation of production of microRNAs involved in gene silencing by microRNA;   downregulation of gene silencing by miRNA, production of miRNAs;   downregulation of miRNA processing;   downregulation of miRNA-mediated gene silencing, production of miRNAs;   downregulation of microRNA-mediated gene silencing, production of microRNAs;   downregulation of production of miRNAs involved in gene silencing by miRNA;   downregulation of production of microRNAs involved in gene silencing by microRNA;   negative regulation of gene silencing by miRNA, production of miRNAs;   negative regulation of miRNA processing;   negative regulation of miRNA-mediated gene silencing, production of miRNAs;   negative regulation of microRNA-mediated gene silencing, production of microRNAs;   negative regulation of production of microRNAs involved in gene silencing by microRNA
 narrow_synonym: inhibition of gene silencing by miRNA, production of miRNAs;   inhibition of miRNA processing;   inhibition of miRNA-mediated gene silencing, production of miRNAs;   inhibition of microRNA-mediated gene silencing, production of microRNAs;   inhibition of production of miRNAs involved in gene silencing by miRNA;   inhibition of production of microRNAs involved in gene silencing by microRNA
 related_synonym: down regulation of miRNA biogenesis;   down regulation of microRNA biogenesis;   down regulation of microRNA biosynthesis;   down regulation of microRNA biosynthetic process;   down regulation of microRNA metabolic process;   down regulation of microRNA metabolism;   downregulation of miRNA biogenesis;   downregulation of microRNA biogenesis;   downregulation of microRNA biosynthesis;   downregulation of microRNA biosynthetic process;   downregulation of microRNA metabolic process;   downregulation of microRNA metabolism;   inhibition of miRNA biogenesis;   inhibition of microRNA biogenesis;   inhibition of microRNA biosynthesis;   inhibition of microRNA biosynthetic process;   inhibition of microRNA metabolic process;   inhibition of microRNA metabolism;   negative regulation of miRNA biogenesis;   negative regulation of microRNA biogenesis;   negative regulation of microRNA biosynthesis;   negative regulation of microRNA biosynthetic process;   negative regulation of microRNA metabolic process;   negative regulation of microRNA metabolism;   negative regulation of production of miRNAs involved in gene silencing by miRNA



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negative regulation of miRNA maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 involved_in ISO
IEA
(PMID:20388878)
GO_REF:0000107
RGD
Ensembl
PMID:20388878 GO_REF:0000107 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Hnf1a HNF1 homeobox A IMP RGD PMID:23674172 RGD:150540303 NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 involved_in ISO (PMID:20388878) RGD PMID:20388878 NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032
JBrowse link
G Ncor2 nuclear receptor co-repressor 2 involved_in ISO (PMID:20388878) RGD PMID:20388878 NCBI chr12:31,466,418...31,628,319
Ensembl chr12:31,466,412...31,628,319
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha involved_in ISO (MGI:5562625|PMID:24161931) RGD PMID:24161931 MGI:5562625 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974
JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO RNAcentral:URS000024463E_9606 (PMID:22269326) RGD PMID:22269326 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within ISO (PMID:31124343), (PMID:31824476) RGD PMID:31124343 PMID:31824476 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO MGI:1890508 (MGI:5013521|PMID:21522133) RGD PMID:21522133 MGI:5013521 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Zc3h10 zinc finger CCCH type containing 10 involved_in ISO (PMID:28431233) RGD PMID:28431233 NCBI chr 7:973,415...977,742
Ensembl chr 7:972,855...979,349
JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A involved_in ISS
ISO
GO_REF:0000024
(PMID:22055188)
UniProt
RGD
PMID:22055188 GO_REF:0000024 NCBI chr 5:137,376,562...137,385,351
Ensembl chr 5:137,376,564...137,385,351
JBrowse link
G Zmpste24 zinc metallopeptidase STE24 acts_upstream_of_or_within ISO MGI:2180033|MGI:98834 (MGI:5013521|PMID:21522133) RGD PMID:21522133 MGI:5013521 NCBI chr 5:134,627,218...134,660,360
Ensembl chr 5:134,627,229...134,660,110
JBrowse link
negative regulation of pre-miRNA processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcdin3d BCDIN3 domain containing RNA methyltransferase involved_in ISO
IBA
ISS
(PMID:23063121)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:23063121 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 7:130,605,540...130,610,134
Ensembl chr 7:130,605,541...130,610,115
JBrowse link
G Lin28b lin-28 homolog B involved_in ISO (PMID:18951094) RGD PMID:18951094 NCBI chr20:48,865,329...48,964,769
Ensembl chr20:48,869,485...48,955,077
JBrowse link
negative regulation of primary miRNA processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il6 interleukin 6 acts_upstream_of ISO UniProtKB:P40763 (PMID:31507089) RGD PMID:31507089 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Lin28b lin-28 homolog B involved_in ISO (PMID:18951094) RGD PMID:18951094 NCBI chr20:48,865,329...48,964,769
Ensembl chr20:48,869,485...48,955,077
JBrowse link
G Mecp2 methyl CpG binding protein 2 IMP RGD PMID:24636259 RGD:12789709 NCBI chr  X:151,781,177...151,844,687
Ensembl chr  X:151,789,930...151,844,689
JBrowse link
G Stat3 signal transducer and activator of transcription 3 involved_in ISO (PMID:31507089) RGD PMID:31507089 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18737
    metabolic process 11461
      negative regulation of metabolic process 3299
        negative regulation of macromolecule metabolic process 3067
          negative regulation of gene expression 1262
            negative regulation of miRNA maturation 16
              negative regulation of pre-miRNA processing 2
              negative regulation of primary miRNA processing 4
Path 2
Term Annotations click to browse term
  biological_process 18737
    metabolic process 11461
      nitrogen compound metabolic process 9715
        cellular nitrogen compound metabolic process 6419
          nucleobase-containing compound metabolic process 5336
            nucleic acid metabolic process 4845
              RNA metabolic process 4281
                ncRNA metabolic process 630
                  ncRNA processing 431
                    small regulatory ncRNA processing 58
                      regulation of production of small RNA involved in gene silencing by RNA 29
                        regulation of miRNA maturation 27
                          negative regulation of miRNA maturation 16
                            negative regulation of pre-miRNA processing 2
                            negative regulation of primary miRNA processing 4
paths to the root