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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of phospholipid metabolic process
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Accession:GO:1903726 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid metabolic process.
Synonyms:exact_synonym: down regulation of phospholipid metabolic process;   down regulation of phospholipid metabolism;   downregulation of phospholipid metabolic process;   downregulation of phospholipid metabolism;   negative regulation of phospholipid metabolism
 narrow_synonym: inhibition of phospholipid metabolic process;   inhibition of phospholipid metabolism


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negative regulation of phosphatidylcholine biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lpcat1 lysophosphatidylcholine acyltransferase 1 ISO (MGI:MGI:4460850|PMID:20018880) MGI PMID:20018880 MGI:MGI:4460850 NCBI chrNW_004936815:281,664...345,915 JBrowse link
negative regulation of phosphatidylcholine catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc1 apolipoprotein C1 ISO (PMID:2302419) BHF-UCL PMID:2302419 NCBI chrNW_004936706:1,519,248...1,520,102 JBrowse link
negative regulation of phosphatidylinositol 3-kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dab2ip DAB2 interacting protein ISO (PMID:19903888) UniProtKB PMID:19903888 NCBI chrNW_004936487:10,056,809...10,243,021 JBrowse link
G Pik3ip1 phosphoinositide-3-kinase interacting protein 1 ISO (PMID:17475214)
(MGI:MGI:3806716|PMID:18632611)
UniProtKB PMID:17475214, PMID:18632611 MGI:MGI:3806716 NCBI chrNW_004936755:444,264...456,071 JBrowse link
G Rubcn rubicon autophagy regulator ISO (PMID:21062745) UniProtKB PMID:21062745 NCBI chrNW_004936784:370,173...438,263 JBrowse link
G Washc1 WASH complex subunit 1 ISO (MGI:MGI:5519172|PMID:23974797) UniProtKB PMID:23974797 MGI:MGI:5519172 NCBI chrNW_004936606:209,289...228,986 JBrowse link
negative regulation of phosphatidylinositol biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfa platelet derived growth factor subunit A ISO (PMID:2538439) BHF-UCL PMID:2538439 NCBI chrNW_004936754:808,894...828,554 JBrowse link
G Pdgfb platelet derived growth factor subunit B ISO (PMID:2538439) BHF-UCL PMID:2538439 NCBI chrNW_004936492:2,353,840...2,368,573 JBrowse link
negative regulation of phospholipid biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 ISO PMID:24201375
(PMID:24201375)
ARUK-UCL PMID:24201375 RGD:14697729 NCBI chrNW_004936669:922,978...941,996 JBrowse link
G Slc27a1 solute carrier family 27 member 1 ISO (PMID:19523918) UniProtKB PMID:19523918 NCBI chrNW_004936596:3,426,807...3,451,259 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11966
    negative regulation of biological process 4647
      negative regulation of metabolic process 2541
        negative regulation of lipid metabolic process 95
          negative regulation of phospholipid metabolic process 10
            negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process 0
            negative regulation of 1-phosphatidylinositol 4-kinase activity 0
            negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity 0
            negative regulation of cardiolipin metabolic process 0
            negative regulation of phosphatidylcholine catabolic process 1
            negative regulation of phosphatidylethanolamine metabolic process 0
            negative regulation of phosphatidylinositol 3-kinase activity + 4
            negative regulation of phosphatidylserine metabolic process + 0
            negative regulation of phospholipid biosynthetic process + 5
Path 2
Term Annotations click to browse term
  biological_process 11966
    biological regulation 8758
      regulation of biological process 8309
        regulation of metabolic process 5090
          negative regulation of metabolic process 2541
            negative regulation of cellular metabolic process 2154
              negative regulation of phosphorus metabolic process 529
                negative regulation of phosphate metabolic process 529
                  negative regulation of phospholipid metabolic process 10
                    negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process 0
                    negative regulation of 1-phosphatidylinositol 4-kinase activity 0
                    negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity 0
                    negative regulation of cardiolipin metabolic process 0
                    negative regulation of phosphatidylcholine catabolic process 1
                    negative regulation of phosphatidylethanolamine metabolic process 0
                    negative regulation of phosphatidylinositol 3-kinase activity + 4
                    negative regulation of phosphatidylserine metabolic process + 0
                    negative regulation of phospholipid biosynthetic process + 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.