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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of response to endoplasmic reticulum stress
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Accession:GO:1903573 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of a response to endoplasmic reticulum stress.
Synonyms:exact_synonym: down regulation of ER stress response;   down regulation of cellular response to endoplasmic reticulum stress;   down regulation of response to ER stress;   down regulation of response to endoplasmic reticulum stress;   downregulation of ER stress response;   downregulation of cellular response to endoplasmic reticulum stress;   downregulation of response to ER stress;   downregulation of response to endoplasmic reticulum stress;   negative regulation of ER stress response;   negative regulation of cellular response to endoplasmic reticulum stress;   negative regulation of response to ER stress
 narrow_synonym: inhibition of ER stress response;   inhibition of cellular response to endoplasmic reticulum stress;   inhibition of response to ER stress;   inhibition of response to endoplasmic reticulum stress


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negative regulation of response to endoplasmic reticulum stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox5 arachidonate 5-lipoxygenase involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:5926685|PMID:28694473)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:28694473 GO_REF:0000024 GO_REF:0000107 MGI:5926685 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
JBrowse link
G Aqp11 aquaporin 11 involved_in ISS
ISO
GO_REF:0000024
(MGI:3813160|PMID:18606867)
UniProt
RGD
PMID:18606867 GO_REF:0000024 MGI:3813160 NCBI chr 1:162,703,394...162,713,560
Ensembl chr 1:162,703,442...162,713,610
JBrowse link
G Clu clusterin involved_in ISO
IEA
(PMID:21803450)
GO_REF:0000107
RGD
Ensembl
PMID:21803450 GO_REF:0000107 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
JBrowse link
G Lpcat3 lysophosphatidylcholine acyltransferase 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:5548036|PMID:24206663)
UniProt
RGD
PMID:24206663 GO_REF:0000024 MGI:5548036 NCBI chr 4:157,181,722...157,222,997
Ensembl chr 4:157,181,795...157,222,996
JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:5548036|PMID:24206663)
UniProt
RGD
PMID:24206663 GO_REF:0000024 MGI:5548036 NCBI chr 1:100,554,577...100,559,896
Ensembl chr 1:100,554,544...100,559,942
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:5548036|PMID:24206663)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:24206663 GO_REF:0000024 GO_REF:0000107 MGI:5548036 NCBI chr 3:80,004,130...80,014,197
Ensembl chr 3:80,004,130...80,012,750
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A involved_in ISO (MGI:5605960|PMID:11381086) RGD PMID:11381086 MGI:5605960 NCBI chr 1:101,511,899...101,515,043
Ensembl chr 1:101,511,901...101,514,974
JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein involved_in ISO (PMID:23035048) RGD PMID:23035048 NCBI chr14:78,640,707...78,665,224
Ensembl chr14:78,640,620...78,665,966
JBrowse link
negative regulation of ATF6-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf6b activating transcription factor 6 beta involved_in ISO (PMID:9837962) RGD PMID:9837962 NCBI chr20:4,414,283...4,422,283
Ensembl chr20:4,414,276...4,422,283
JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein involved_in IGI
ISO
PMID:20160352
(PMID:20160352)
RGD PMID:20160352, PMID:20160352 RGD:10047363 NCBI chr14:78,640,707...78,665,224
Ensembl chr14:78,640,620...78,665,966
JBrowse link
negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 involved_in ISO
ISS
(PMID:22064321)
(MGI:5617428|PMID:25329545)
GO_REF:0000024
RGD
UniProt
PMID:22064321 PMID:25329545 GO_REF:0000024 MGI:5617428 NCBI chr15:104,186,918...104,226,236
Ensembl chr15:104,186,792...104,226,329
JBrowse link
G Nck1 NCK adaptor protein 1 involved_in ISO (PMID:14676213), (PMID:16835242)
UniProtKB:O55033 (MGI:5613475|PMID:16835242), (MGI:5613478|PMID:14676213)
RGD PMID:14676213 PMID:16835242 MGI:5613475 MGI:5613478 NCBI chr 8:108,787,797...108,847,779
Ensembl chr 8:108,787,798...108,847,779
JBrowse link
G Nck2 NCK adaptor protein 2 involved_in ISO (PMID:16835242)
UniProtKB:Q99M51 (MGI:5613475|PMID:16835242), (MGI:5613478|PMID:14676213)
RGD PMID:14676213 PMID:16835242 MGI:5613475 MGI:5613478 NCBI chr 9:50,246,767...50,373,307
Ensembl chr 9:50,247,692...50,373,284
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A involved_in ISO (MGI:5613475|PMID:16835242) RGD PMID:16835242 MGI:5613475 NCBI chr 1:101,511,899...101,515,043
Ensembl chr 1:101,511,901...101,514,974
JBrowse link
G Ppp1r15b protein phosphatase 1, regulatory subunit 15B involved_in ISO (MGI:5613475|PMID:16835242) RGD PMID:16835242 MGI:5613475 NCBI chr13:49,933,155...49,940,961
Ensembl chr13:49,933,155...49,940,961
JBrowse link
G Tmed2 transmembrane p24 trafficking protein 2 acts_upstream_of_or_within ISO MGI:4456438 (MGI:5914333|PMID:28797121) RGD PMID:28797121 MGI:5914333 NCBI chr12:37,471,259...37,480,344
Ensembl chr12:37,471,260...37,480,297
JBrowse link
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2l1 Bcl2-like 1 involved_in ISO
ISS
(PMID:29507230)
GO_REF:0000024
RGD
UniProt
PMID:29507230 GO_REF:0000024 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Creb3 cAMP responsive element binding protein 3 involved_in ISO (PMID:16940180) RGD PMID:16940180 NCBI chr 5:59,063,532...59,068,196
Ensembl chr 5:59,063,531...59,068,188
JBrowse link
G Creb3l1 cAMP responsive element binding protein 3-like 1 involved_in IMP
ISO
PMID:15665855
(MGI:5616321|PMID:15665855)
RGD PMID:15665855, PMID:15665855 MGI:5616321, RGD:1558627 NCBI chr 3:80,892,433...80,933,283
Ensembl chr 3:80,892,435...80,933,283
JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 acts_upstream_of_or_within ISO MGI:1341830|MGI:99682 (MGI:5525071|PMID:22240901) RGD PMID:22240901 MGI:5525071 NCBI chr 7:117,304,742...117,307,916
Ensembl chr 7:117,304,742...117,307,916
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in ISO
IMP
IBA
(PMID:15102845)
PMID:21873635
RGD PMID:15102845, PMID:15102845, PMID:21873635 RGD:1304324, RGD:13792537 NCBI chr19:11,046,905...11,057,440
Ensembl chr19:11,046,909...11,057,254
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:12150907), (PMID:20625543) RGD PMID:12150907 PMID:20625543 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:12150907), (PMID:20625543) RGD PMID:12150907 PMID:20625543 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma involved_in ISO (MGI:5495588|PMID:23453807) RGD PMID:23453807 MGI:5495588 NCBI chr  X:156,254,187...156,280,046
Ensembl chr  X:156,257,173...156,270,748
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (PMID:21857923) RGD PMID:21857923 NCBI chr 7:132,857,311...133,018,549
Ensembl chr 7:132,857,628...133,018,584
JBrowse link
G Ngf nerve growth factor involved_in NAS PMID:21266243 ParkinsonsUK-UCL PMID:21266243 RGD:10047230 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase involved_in ISS
ISO
GO_REF:0000024
(MGI:5495588|PMID:23453807)
UniProtKB:P58281 (PMID:23453807)
ParkinsonsUK-UCL
RGD
PMID:23453807 GO_REF:0000024 MGI:5495588 NCBI chr11:74,717,600...74,793,902
Ensembl chr11:74,720,254...74,793,803
JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO
IEA
UniProtKB:Q99LX0 (PMID:14652021)
(MGI:5613479|PMID:14652021)
GO_REF:0000107
RGD
Ensembl
PMID:14652021 GO_REF:0000107 MGI:5613479 NCBI chr 5:167,982,438...168,004,724
Ensembl chr 5:167,982,439...168,004,724
JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 acts_upstream_of_or_within ISO MGI:2181360 (MGI:4836774|PMID:20811152) RGD PMID:20811152 MGI:4836774 NCBI chr12:9,496,044...9,501,211
Ensembl chr12:9,496,044...9,501,213
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISS
ISO
GO_REF:0000024
(MGI:5433837|PMID:21113145)
(PMID:10973942), (PMID:11439185), (PMID:12150907), (PMID:21113145), (PMID:23453807)
ParkinsonsUK-UCL
RGD
PMID:10973942 PMID:11439185 PMID:12150907 PMID:21113145 PMID:23453807 GO_REF:0000024 MGI:5433837 NCBI chr 1:48,880,015...50,069,998 JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 involved_in ISO (MGI:5619464|PMID:21216966) RGD PMID:21216966 MGI:5619464 NCBI chr 3:164,665,462...164,711,936
Ensembl chr 3:164,665,532...164,711,848
JBrowse link
G Selenos selenoprotein S involved_in ISO
IEA
(PMID:17210132)
GO_REF:0000107
RGD
Ensembl
PMID:17210132 GO_REF:0000107 NCBI chr 1:126,979,579...126,989,344
Ensembl chr 1:126,979,575...126,989,344
JBrowse link
G Syvn1 synoviolin 1 involved_in
acts_upstream_of_or_within
ISO (PMID:12459480), (PMID:17059562)
MGI:2679656 (MGI:3575050|PMID:15611074)
RGD PMID:12459480 PMID:15611074 PMID:17059562 MGI:3575050 NCBI chr 1:221,409,281...221,416,229
Ensembl chr 1:221,409,271...221,417,886
JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 involved_in
acts_upstream_of_or_within
ISO (PMID:21075086)
MGI:1913418 (MGI:5525071|PMID:22240901)
RGD PMID:21075086 PMID:22240901 MGI:5525071 NCBI chr 7:141,039,433...141,070,269
Ensembl chr 7:141,034,982...141,069,989
JBrowse link
G Txndc12 thioredoxin domain containing 12 acts_upstream_of_or_within ISO (PMID:18628206) RGD PMID:18628206 NCBI chr 5:128,450,830...128,475,858
Ensembl chr 5:128,450,680...128,475,864
JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein involved_in ISO (MGI:3629256|PMID:16571599) RGD PMID:16571599 MGI:3629256 NCBI chr14:78,640,707...78,665,224
Ensembl chr14:78,640,620...78,665,966
JBrowse link
G Xbp1 X-box binding protein 1 involved_in IEA
IMP
ISO
GO_REF:0000107
PMID:20625543
(PMID:19135031)
Ensembl
RGD
PMID:19135031, PMID:20625543 GO_REF:0000107, RGD:10047191 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145
JBrowse link
negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hyou1 hypoxia up-regulated 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:3697528|PMID:17116640)
Ensembl
RGD
PMID:17116640 GO_REF:0000107 MGI:3697528 NCBI chr 8:48,699,796...48,711,912
Ensembl chr 8:48,699,769...48,711,910
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO UniProtKB:O15354 (MGI:3697528|PMID:17116640), (MGI:5495588|PMID:23453807) RGD PMID:17116640 PMID:23453807 MGI:3697528 MGI:5495588 NCBI chr 1:48,880,015...50,069,998 JBrowse link
negative regulation of endoplasmic reticulum unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crebrf CREB3 regulatory factor involved_in ISO (PMID:18391022) RGD PMID:18391022 NCBI chr10:16,693,846...16,753,162
Ensembl chr10:16,694,792...16,752,205
JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO (PMID:25239945) RGD PMID:25239945 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145
JBrowse link
negative regulation of ER-associated ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sgta small glutamine rich tetratricopeptide repeat co-chaperone alpha involved_in ISO
ISS
(PMID:23129660)
GO_REF:0000024
RGD
UniProt
PMID:23129660 GO_REF:0000024 NCBI chr 7:11,521,949...11,538,691
Ensembl chr 7:11,521,998...11,539,319
JBrowse link
G Svip small VCP interacting protein involved_in IBA
ISO
IC
PMID:21873635
(PMID:17872946)
PMID:17000876
RGD PMID:17872946, PMID:21873635, PMID:17000876 RGD:13792537, RGD:10047192 NCBI chr 1:107,368,117...107,373,807
Ensembl chr 1:107,368,117...107,373,807
JBrowse link
G Usp14 ubiquitin specific peptidase 14 involved_in ISO (PMID:19135427) RGD PMID:19135427 NCBI chr18:1,178,785...1,216,573
Ensembl chr18:1,178,787...1,216,409
JBrowse link
negative regulation of ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp11 aquaporin 11 involved_in ISS
ISO
GO_REF:0000024
(MGI:3813160|PMID:18606867)
UniProt
RGD
PMID:18606867 GO_REF:0000024 MGI:3813160 NCBI chr 1:162,703,394...162,713,560
Ensembl chr 1:162,703,442...162,713,610
JBrowse link
G Ubxn1 UBX domain protein 1 involved_in ISO (PMID:21135095) RGD PMID:21135095 NCBI chr 1:225,067,953...225,071,944
Ensembl chr 1:225,068,009...225,071,945
JBrowse link
G Usp25 ubiquitin specific peptidase 25 involved_in ISO (PMID:22590560) RGD PMID:22590560 NCBI chr11:15,436,080...15,558,646
Ensembl chr11:15,436,269...15,558,646
Ensembl chr11:15,436,269...15,558,646
JBrowse link
negative regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bfar bifunctional apoptosis regulator involved_in ISO (PMID:21068390) RGD PMID:21068390 NCBI chr10:1,464,783...1,497,653
Ensembl chr10:1,464,765...1,497,653
JBrowse link
G Ddrgk1 DDRGK domain containing 1 involved_in ISO (PMID:28128204), (PMID:32160526)
(MGI:5912977|PMID:28128204)
RGD PMID:28128204 PMID:32160526 MGI:5912977 NCBI chr 3:123,195,580...123,206,828
Ensembl chr 3:123,195,580...123,206,828
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 6:64,165,913...64,170,122
Ensembl chr 6:64,165,913...64,170,151
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Pdia6 protein disulfide isomerase family A, member 6 involved_in ISO (MGI:5571560|PMID:24508390) RGD PMID:24508390 MGI:5571560 NCBI chr 6:42,568,269...42,585,654
Ensembl chr 6:42,568,220...42,585,652
JBrowse link
G Ufl1 Ufm1-specific ligase 1 involved_in ISO
ISS
(PMID:32160526)
GO_REF:0000024
RGD
UniProt
PMID:32160526 GO_REF:0000024 NCBI chr 5:39,616,479...39,650,894
Ensembl chr 5:39,615,956...39,650,895
JBrowse link
negative regulation of PERK-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca7 ATP binding cassette subfamily A member 7 involved_in ISO (MGI:5774886|PMID:27030769) RGD PMID:27030769 MGI:5774886 NCBI chr 7:12,742,433...12,762,423
Ensembl chr 7:12,742,433...12,762,341
JBrowse link
G Nck1 NCK adaptor protein 1 involved_in ISO (PMID:14676213)
UniProtKB:O55033 (MGI:5613478|PMID:14676213)
RGD PMID:14676213 MGI:5613478 NCBI chr 8:108,787,797...108,847,779
Ensembl chr 8:108,787,798...108,847,779
JBrowse link
G Nck2 NCK adaptor protein 2 involved_in ISO UniProtKB:Q99M51 (MGI:5613478|PMID:14676213) RGD PMID:14676213 MGI:5613478 NCBI chr 9:50,246,767...50,373,307
Ensembl chr 9:50,247,692...50,373,284
JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 involved_in ISO (PMID:21216966)
(MGI:5619464|PMID:21216966)
RGD PMID:21216966 MGI:5619464 NCBI chr 3:164,665,462...164,711,936
Ensembl chr 3:164,665,532...164,711,848
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19612
    cellular process 18457
      negative regulation of cellular process 5102
        negative regulation of response to endoplasmic reticulum stress 48
          negative regulation of ERAD pathway + 6
          negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation 6
          negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway + 22
          negative regulation of endoplasmic reticulum unfolded protein response + 14
Path 2
Term Annotations click to browse term
  biological_process 19612
    biological regulation 13583
      regulation of biological process 12857
        regulation of response to stimulus 3981
          regulation of response to stress 1297
            regulation of cellular response to stress 675
              regulation of response to endoplasmic reticulum stress 85
                negative regulation of response to endoplasmic reticulum stress 48
                  negative regulation of ERAD pathway + 6
                  negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation 6
                  negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway + 22
                  negative regulation of endoplasmic reticulum unfolded protein response + 14
paths to the root