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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of response to endoplasmic reticulum stress
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Accession:GO:1903573 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of a response to endoplasmic reticulum stress.
Synonyms:exact_synonym: down regulation of ER stress response;   down regulation of cellular response to endoplasmic reticulum stress;   down regulation of response to ER stress;   down regulation of response to endoplasmic reticulum stress;   downregulation of ER stress response;   downregulation of cellular response to endoplasmic reticulum stress;   downregulation of response to ER stress;   downregulation of response to endoplasmic reticulum stress;   negative regulation of ER stress response;   negative regulation of cellular response to endoplasmic reticulum stress;   negative regulation of response to ER stress
 narrow_synonym: inhibition of ER stress response;   inhibition of cellular response to endoplasmic reticulum stress;   inhibition of response to ER stress;   inhibition of response to endoplasmic reticulum stress


show annotations for term's descendants           Sort by:
negative regulation of response to endoplasmic reticulum stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox5 arachidonate 5-lipoxygenase involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:28694473)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:28694473 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:151,203,948...151,251,126
Ensembl chr 4:149,531,515...149,578,743 		JBrowse link
G Aqp11 aquaporin 11 involved_in ISS
ISO		 GO_REF:0000024
(PMID:18606867)		 UniProt
RGD		 PMID:18606867 GO_REF:0000024 NCBI chr 1:161,457,752...161,467,918
Ensembl chr 1:152,046,517...152,056,725 		JBrowse link
G Clu clusterin involved_in ISO
IEA		 (PMID:21803450)
GO_REF:0000107		 RGD
Ensembl		 PMID:21803450 GO_REF:0000107 NCBI chr15:44,336,619...44,375,861
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Lpcat3 lysophosphatidylcholine acyltransferase 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:24206663)		 UniProt
RGD		 PMID:24206663 GO_REF:0000024 NCBI chr 4:159,154,690...159,196,176
Ensembl chr 4:157,468,290...157,509,880 		JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:24206663)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:24206663 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:104,178,483...104,183,863
Ensembl chr 1:95,041,967...95,047,377 		JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:24206663)		 UniProt
Ensembl
RGD		 PMID:24206663 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:97,614,616...97,632,053
Ensembl chr 3:77,158,808...77,168,722 		JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein involved_in ISO
IEA		 (PMID:23035048)
GO_REF:0000107		 RGD
Ensembl		 PMID:23035048 GO_REF:0000107 NCBI chr14:78,035,205...78,059,718
Ensembl chr14:73,810,404...73,835,602 		JBrowse link
negative regulation of ATF6-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf6b activating transcription factor 6 beta involved_in ISO
IEA		 (PMID:9837962)
GO_REF:0000107		 RGD
Ensembl		 PMID:9837962 GO_REF:0000107 NCBI chr20:4,095,534...4,103,534
Ensembl chr20:4,090,921...4,098,894 		JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein involved_in IGI
IEA
ISO		 PMID:20160352
GO_REF:0000107
(PMID:20160352)		 Ensembl
RGD		 PMID:20160352 PMID:20160352 GO_REF:0000107, RGD:10047363 NCBI chr14:78,035,205...78,059,718
Ensembl chr14:73,810,404...73,835,602 		JBrowse link
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2l1 Bcl2-like 1 involved_in ISO
ISS		 (PMID:29507230)
GO_REF:0000024		 RGD
UniProt		 PMID:29507230 GO_REF:0000024 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479 		JBrowse link
G Creb3 cAMP responsive element binding protein 3 involved_in ISO
IEA		 (PMID:16940180)
GO_REF:0000107		 RGD
Ensembl		 PMID:16940180 GO_REF:0000107 NCBI chr 5:62,613,652...62,619,019
Ensembl chr 5:57,817,832...57,824,390 		JBrowse link
G Creb3l1 cAMP responsive element binding protein 3-like 1 involved_in IMP
ISO		 PMID:15665855
(PMID:15665855)		 RGD PMID:15665855 PMID:15665855 RGD:1558627 NCBI chr 3:98,408,240...98,449,104
Ensembl chr 3:77,952,540...77,993,456 		JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 acts_upstream_of_or_within ISO
IEA		 MGI:1341830|MGI:99682 (PMID:22240901)
GO_REF:0000107		 RGD
Ensembl		 PMID:22240901 GO_REF:0000107 NCBI chr 7:109,842,870...109,846,048
Ensembl chr 7:107,962,207...107,965,366 		JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in ISO
IEA
IBA		 (PMID:15102845)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:15102845 GO_REF:0000033 GO_REF:0000107 NCBI chr19:10,604,360...10,624,168
Ensembl chr19:10,598,417...10,618,424 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:12150907), (PMID:20625543) RGD PMID:12150907 PMID:20625543 NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:12150907), (PMID:20625543) RGD PMID:12150907 PMID:20625543 NCBI chr20:3,859,756...3,863,800
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma involved_in ISO (PMID:23453807) RGD PMID:23453807 NCBI chr  X:157,358,279...157,397,563
Ensembl chr  X:152,216,596...152,239,499 		JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO
IEA		 (PMID:21857923)
GO_REF:0000107		 RGD
Ensembl		 PMID:21857923 GO_REF:0000107 NCBI chr 7:124,706,246...124,867,234
Ensembl chr 7:122,826,696...122,987,703 		JBrowse link
G Ngf nerve growth factor involved_in NAS PMID:21266243 ParkinsonsUK-UCL PMID:21266243 RGD:10047230 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:23453807)
UniProtKB:P58281 (PMID:23453807)		 ParkinsonsUK-UCL
Ensembl
RGD		 PMID:23453807 GO_REF:0000024 GO_REF:0000107 NCBI chr11:84,612,943...84,690,025
Ensembl chr11:71,109,873...71,185,109 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO UniProtKB:Q99LX0 (PMID:14652021) RGD PMID:14652021 NCBI chr 5:166,636,551...166,659,825
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 acts_upstream_of_or_within ISO
IEA		 MGI:2181360 (PMID:20811152)
GO_REF:0000107		 RGD
Ensembl		 PMID:20811152 GO_REF:0000107 NCBI chr12:12,793,957...12,799,156
Ensembl chr12:7,757,865...7,763,064 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:21113145)
(PMID:10973942), (PMID:11439185), (PMID:12150907), (PMID:21113145), (PMID:23453807)		 ParkinsonsUK-UCL
Ensembl
RGD		 PMID:10973942 PMID:11439185 PMID:12150907 PMID:21113145 PMID:23453807 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 involved_in ISO
IEA		 (PMID:21216966)
GO_REF:0000107		 RGD
Ensembl		 PMID:21216966 GO_REF:0000107 NCBI chr 3:177,056,588...177,106,424
Ensembl chr 3:156,638,769...156,687,504 		JBrowse link
G Selenos selenoprotein S involved_in ISO
IEA		 (PMID:17210132)
GO_REF:0000107		 RGD
Ensembl		 PMID:17210132 GO_REF:0000107 NCBI chr 1:129,070,240...129,080,007
Ensembl chr 1:119,659,751...119,669,833 		JBrowse link
G Syvn1 synoviolin 1 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:12459480), (PMID:17059562)
GO_REF:0000107
MGI:2679656 (PMID:15611074)		 RGD
Ensembl		 PMID:12459480 PMID:15611074 PMID:17059562 GO_REF:0000107 NCBI chr 1:212,766,736...212,775,426
Ensembl chr 1:203,339,619...203,346,152 		JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 involved_in
acts_upstream_of_or_within		 ISO (PMID:21075086)
MGI:1913418 (PMID:22240901)		 RGD PMID:21075086 PMID:22240901 NCBI chr 7:132,405,217...132,422,492
Ensembl chr 7:130,527,316...130,543,633 		JBrowse link
G Txndc12 thioredoxin domain containing 12 acts_upstream_of_or_within ISO
IEA		 (PMID:18628206)
GO_REF:0000107		 RGD
Ensembl		 PMID:18628206 GO_REF:0000107 NCBI chr 5:128,815,471...128,841,574
Ensembl chr 5:123,586,781...123,612,870 		JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein involved_in ISO
IEA		 (PMID:16571599)
GO_REF:0000107		 RGD
Ensembl		 PMID:16571599 GO_REF:0000107 NCBI chr14:78,035,205...78,059,718
Ensembl chr14:73,810,404...73,835,602 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO
IEA
IMP		 (PMID:19135031)
GO_REF:0000107
PMID:20625543		 RGD
Ensembl		 PMID:19135031 PMID:20625543 GO_REF:0000107, RGD:10047191 NCBI chr14:84,604,623...84,609,707
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hyou1 hypoxia up-regulated 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:17116640)		 Ensembl
RGD		 PMID:17116640 GO_REF:0000107 NCBI chr 8:53,602,882...53,614,998
Ensembl chr 8:44,706,263...44,718,186 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:O15354 (PMID:17116640), (PMID:23453807)		 Ensembl
RGD		 PMID:17116640 PMID:23453807 GO_REF:0000107 NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
negative regulation of endoplasmic reticulum unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crebrf CREB3 regulatory factor involved_in ISO (PMID:18391022) RGD PMID:18391022 NCBI chr10:16,903,607...16,967,450
Ensembl chr10:16,404,596...16,461,999 		JBrowse link
G Mir199a2 microRNA 199a-2 acts_upstream_of ISO (PMID:24299514) RGD PMID:24299514 NCBI chr13:77,116,225...77,116,334
Ensembl chr13:74,582,954...74,583,063 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO (PMID:25239945) RGD PMID:25239945 NCBI chr14:84,604,623...84,609,707
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
negative regulation of ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp11 aquaporin 11 involved_in ISS
ISO		 GO_REF:0000024
(PMID:18606867)		 UniProt
RGD		 PMID:18606867 GO_REF:0000024 NCBI chr 1:161,457,752...161,467,918
Ensembl chr 1:152,046,517...152,056,725 		JBrowse link
G Sgta small glutamine rich tetratricopeptide repeat co-chaperone alpha involved_in ISS
ISO		 GO_REF:0000024
(PMID:23129660)		 UniProt
RGD		 PMID:23129660 GO_REF:0000024 NCBI chr 7:9,304,381...9,321,157
Ensembl chr 7:8,653,778...8,670,458 		JBrowse link
G Svip small VCP interacting protein involved_in IDA
ISO
IBA		 PMID:17000876
(PMID:17872946)
GO_REF:0000033		 RGD
GO_Central		 PMID:17872946 PMID:17000876 GO_REF:0000033, RGD:10047192 NCBI chr 1:110,723,051...110,728,741
Ensembl chr 1:101,587,128...101,593,116 		JBrowse link
G Ubxn1 UBX domain protein 1 involved_in ISO (PMID:21135095) RGD PMID:21135095 NCBI chr 1:215,194,418...215,198,343
Ensembl chr 1:205,745,120...205,816,520 		JBrowse link
G Ubxn2a UBX domain protein 2A involved_in ISS
ISO		 GO_REF:0000024
(PMID:26265139)		 UniProt
RGD		 PMID:26265139 GO_REF:0000024 NCBI chr 6:33,603,804...33,645,958
Ensembl chr 6:27,884,680...27,912,649
Ensembl chr20:27,884,680...27,912,649 		JBrowse link
G Usp14 ubiquitin specific peptidase 14 involved_in ISO
IBA		 (PMID:19135427)
GO_REF:0000033		 RGD
GO_Central		 PMID:19135427 GO_REF:0000033 NCBI chr18:1,292,745...1,330,867
Ensembl chr18:1,019,400...1,057,519 		JBrowse link
G Usp25 ubiquitin specific peptidase 25 involved_in ISO
IEA		 (PMID:22590560)
GO_REF:0000107		 RGD
Ensembl		 PMID:22590560 GO_REF:0000107 NCBI chr11:29,088,283...29,198,323
Ensembl chr11:15,603,881...15,711,348 		JBrowse link
negative regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bfar bifunctional apoptosis regulator involved_in ISO
IEA		 (PMID:21068390)
GO_REF:0000107		 RGD
Ensembl		 PMID:21068390 GO_REF:0000107 NCBI chr10:2,059,189...2,092,207
Ensembl chr10:1,552,072...1,585,038 		JBrowse link
G Ddrgk1 DDRGK domain containing 1 involved_in ISO
IEA
IBA		 (PMID:28128204), (PMID:32160526)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:28128204 PMID:32160526 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:138,315,006...138,336,691
Ensembl chr 3:117,861,653...117,882,680 		JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 6:66,997,842...67,007,371
Ensembl chr 6:61,269,913...61,275,063 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Pdia6 protein disulfide isomerase family A, member 6 involved_in ISO (PMID:24508390) RGD PMID:24508390 NCBI chr 6:45,791,704...45,808,947
Ensembl chr 6:40,062,926...40,080,613 		JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 involved_in ISO (PMID:19328063) RGD PMID:19328063 NCBI chr 7:132,405,217...132,422,492
Ensembl chr 7:130,527,316...130,543,633 		JBrowse link
G Ufl1 Ufm1-specific ligase 1 involved_in ISO
IEA
ISS		 (PMID:32160526)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:32160526 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:43,759,271...43,791,682
Ensembl chr 5:38,962,171...38,995,199 		JBrowse link
negative regulation of PERK-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca7 ATP binding cassette subfamily A member 7 involved_in ISO (PMID:27030769) RGD PMID:27030769 NCBI chr 7:10,342,092...10,362,094
Ensembl chr 7:9,691,449...9,711,425 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:21954288)		 Ensembl
RGD		 PMID:21954288 GO_REF:0000107 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Akt2 AKT serine/threonine kinase 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:21954288)		 Ensembl
RGD		 PMID:21954288 GO_REF:0000107 NCBI chr 1:92,004,705...92,061,420
Ensembl chr 1:82,883,547...82,933,817 		JBrowse link
G Akt3 AKT serine/threonine kinase 3 involved_in ISO (PMID:21954288) RGD PMID:21954288 NCBI chr13:91,475,839...91,758,060
Ensembl chr13:88,946,091...89,225,708 		JBrowse link
G Atad3a ATPase family, AAA domain containing 3A involved_in ISO
IEA
ISS		 (PMID:39116259)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:39116259 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:171,632,545...171,652,725
Ensembl chr 5:166,350,304...166,370,482 		JBrowse link
G Ddrgk1 DDRGK domain containing 1 involved_in ISO
IEA		 (PMID:30842412)
GO_REF:0000107		 RGD
Ensembl		 PMID:30842412 GO_REF:0000107 NCBI chr 3:138,315,006...138,336,691
Ensembl chr 3:117,861,653...117,882,680 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 involved_in ISO
IEA		 (PMID:11907036)
GO_REF:0000107		 RGD
Ensembl		 PMID:11907036 GO_REF:0000107 NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Nck1 NCK adaptor protein 1 involved_in ISO
IEA
IBA		 (PMID:14676213)
GO_REF:0000107
GO_REF:0000033
UniProtKB:O55033 (PMID:14676213)		 RGD
Ensembl
GO_Central		 PMID:14676213 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:109,897,723...109,958,247
Ensembl chr 8:101,018,702...101,079,300 		JBrowse link
G Nck2 NCK adaptor protein 2 involved_in ISO
IEA
IBA		 UniProtKB:Q99M51 (PMID:14676213)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:14676213 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:53,206,006...53,332,417
Ensembl chr 9:45,714,883...45,840,307 		JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 involved_in ISO
IBA
IEA		 (PMID:21216966)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:21216966 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:177,056,588...177,106,424
Ensembl chr 3:156,638,769...156,687,504 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20567
    cellular process 19557
      negative regulation of cellular process 5622
        negative regulation of response to endoplasmic reticulum stress 50
          negative regulation of ERAD pathway 7
          negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway + 22
          negative regulation of endoplasmic reticulum unfolded protein response + 20
Path 2
Term Annotations click to browse term
  biological_process 20567
    biological regulation 13841
      regulation of biological process 13403
        regulation of response to stimulus 4358
          regulation of response to stress 1484
            regulation of cellular response to stress 526
              regulation of response to endoplasmic reticulum stress 87
                negative regulation of response to endoplasmic reticulum stress 50
                  negative regulation of ERAD pathway 7
                  negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway + 22
                  negative regulation of endoplasmic reticulum unfolded protein response + 20
paths to the root