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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of blood circulation
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Accession:GO:1903524 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of blood circulation.
Synonyms:exact_synonym: up regulation of blood circulation;   upregulation of blood circulation
 narrow_synonym: activation of blood circulation
 related_synonym: activation of hemolymph circulation;   positive regulation of hemolymph circulation;   up regulation of hemolymph circulation;   upregulation of hemolymph circulation

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positive regulation of cardiac muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace2 angiotensin converting enzyme 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936470:4,964,526...5,011,808
Ensembl chrNW_004936470:4,965,332...5,011,702 		JBrowse link
G Adra1a adrenoceptor alpha 1A involved_in ISO PMID:19011682 BHF-UCL PMID:19011682 RGD:5688340 NCBI chrNW_004936757:149,366...237,710
Ensembl chrNW_004936757:150,496...237,710 		JBrowse link
G Ccn2 cellular communication network factor 2 ISO RGD PMID:19707545 RGD:2314476 NCBI chrNW_004936560:42,561...45,748
Ensembl chrNW_004936560:42,537...45,807 		JBrowse link
G Chga chromogranin A involved_in ISO PMID:22459152 UniProt PMID:22459152 RGD:6906968 NCBI chrNW_004936733:915,700...927,220
Ensembl chrNW_004936733:915,830...927,409 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 ISO RGD PMID:21620734 RGD:5686387 NCBI chrNW_004936835:316,767...321,999
Ensembl chrNW_004936835:316,767...321,990 		JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936794:707,122...994,206
Ensembl chrNW_004936794:707,119...994,778 		JBrowse link
G Nppa natriuretic peptide A involved_in ISO (PMID:19646991) BHF-UCL PMID:19646991 NCBI chrNW_004936474:671,362...673,610 JBrowse link
G Rgs2 regulator of G protein signaling 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936638:1,065,866...1,068,649
Ensembl chrNW_004936638:1,065,832...1,069,247 		JBrowse link
G Smtn smoothelin acts_upstream_of_or_within ISO (PMID:18678771) MGI PMID:18678771 NCBI chrNW_004936755:264,635...285,668
Ensembl chrNW_004936755:264,570...289,260 		JBrowse link
G Ucn urocortin ISO RGD PMID:19460778 RGD:5508168 NCBI chrNW_004936493:5,258,574...5,260,692
Ensembl chrNW_004936493:5,260,219...5,260,602 		JBrowse link
positive regulation of cerebral blood circulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dusp5 dual specificity phosphatase 5 ISO RGD PMID:25397684 RGD:13446412 NCBI chrNW_004936486:1,351,077...1,361,002
Ensembl chrNW_004936486:1,347,885...1,359,903 		JBrowse link
positive regulation of gastric mucosal blood circulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghrl ghrelin and obestatin prepropeptide ISO RGD PMID:17033095 RGD:12910734 NCBI chrNW_004936602:3,037,862...3,044,863
Ensembl chrNW_004936602:3,038,549...3,042,506 		JBrowse link
G Ptger2 prostaglandin E receptor 2 ISO RGD PMID:10807413 RGD:10043357 NCBI chrNW_004936697:2,440,943...2,453,897
Ensembl chrNW_004936697:2,440,901...2,453,975 		JBrowse link
G Ptger3 prostaglandin E receptor 3 ISO RGD PMID:10807413 RGD:10043357 NCBI chrNW_004936591:1,174,364...1,250,233
Ensembl chrNW_004936591:1,174,069...1,249,410 		JBrowse link
positive regulation of heart contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004936486:4,400,467...4,401,588
Ensembl chrNW_004936486:4,399,915...4,403,149 		JBrowse link
G Apela apelin receptor early endogenous ligand involved_in ISO PMID:26611206 UniProt PMID:26611206 RGD:11534624 NCBI chrNW_004936555:969,902...978,736 JBrowse link
G Apln apelin involved_in ISO PMID:26611206 UniProt PMID:26611206 RGD:11534624 NCBI chrNW_004936479:1,889,930...1,899,811
Ensembl chrNW_004936479:1,890,229...1,899,730 		JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10360172) Ensembl
MGI		 PMID:10360172 GO_REF:0000107 NCBI chrNW_004936627:1,555,151...1,584,370
Ensembl chrNW_004936627:1,554,873...1,584,638 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936706:266,462...277,256
Ensembl chrNW_004936706:269,126...277,256 		JBrowse link
G Hrc histidine rich calcium binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936664:3,088,072...3,092,034
Ensembl chrNW_004936664:3,083,602...3,092,308 		JBrowse link
G Nkx2-5 NK2 homeobox 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936609:2,406,004...2,408,980
Ensembl chrNW_004936609:2,406,004...2,409,046 		JBrowse link
G Tgfb2 transforming growth factor beta 2 involved_in IEA
ISS		 Ensembl
AgBase		 GO_REF:0000024 GO_REF:0000107 NCBI chrNW_004936628:310,720...394,002
Ensembl chrNW_004936628:308,691...394,007 		JBrowse link
positive regulation of heart rate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase acts_upstream_of_or_within ISO (PMID:16626672) MGI PMID:16626672 NCBI chrNW_004936530:2,217,713...2,224,070 JBrowse link
G Adm adrenomedullin involved_in ISO
IEA		 RGD
TreeGrafter
Ensembl		 PMID:19520650 GO_REF:0000107 GO_REF:0000118 RGD:2325635 NCBI chrNW_004936528:8,005,223...8,007,586
Ensembl chrNW_004936528:8,005,189...8,007,643 		JBrowse link
G Adm2 adrenomedullin 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936629:360,845...362,499
Ensembl chrNW_004936629:360,305...362,846 		JBrowse link
G Adm5 adrenomedullin 5 (putative) involved_in ISO (PMID:18434369) UniProt PMID:18434369 NCBI chrNW_004936664:3,503,204...3,505,104 JBrowse link
G Adra1a adrenoceptor alpha 1A ISO RGD PMID:22040923 RGD:5688308 NCBI chrNW_004936757:149,366...237,710
Ensembl chrNW_004936757:150,496...237,710 		JBrowse link
G Adrb1 adrenoceptor beta 1 ISO RGD PMID:9089896 RGD:5129112 NCBI chrNW_004936486:4,400,467...4,401,588
Ensembl chrNW_004936486:4,399,915...4,403,149 		JBrowse link
G Apln apelin ISO RGD PMID:12798955 RGD:1626237 NCBI chrNW_004936479:1,889,930...1,899,811
Ensembl chrNW_004936479:1,890,229...1,899,730 		JBrowse link
G Atp5pf ATP synthase peripheral stalk subunit F6 ISO RGD PMID:12686462 RGD:13800918 NCBI chrNW_004936640:1,916,711...1,924,823 JBrowse link
G Avpr1a arginine vasopressin receptor 1A ISO RGD PMID:18339407 RGD:2300339 NCBI chrNW_004936545:1,788,995...1,795,842
Ensembl chrNW_004936545:1,786,571...1,794,709 		JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 ISO RGD PMID:20060787 RGD:5130949 NCBI chrNW_004936478:6,901,098...6,947,719
Ensembl chrNW_004936478:6,899,017...6,947,790 		JBrowse link
G Edn1 endothelin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936534:885,489...892,292
Ensembl chrNW_004936534:885,287...891,772 		JBrowse link
G Edn2 endothelin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:23,061,219...23,064,525
Ensembl chrNW_004936474:23,060,905...23,064,566 		JBrowse link
G Edn3 endothelin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936530:1,744,216...1,766,602
Ensembl chrNW_004936530:1,744,199...1,765,027 		JBrowse link
G Gch1 GTP cyclohydrolase 1 involved_in ISO (MGI:5629781|PMID:25557619) ParkinsonsUK-UCL PMID:25557619 MGI:5629781 NCBI chrNW_004936697:232,048...275,420 JBrowse link
G Hey2 hes related family bHLH transcription factor with YRPW motif 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15297376) Ensembl
MGI		 PMID:15297376 GO_REF:0000107 NCBI chrNW_004936639:3,705,225...3,714,696
Ensembl chrNW_004936639:3,703,447...3,716,820 		JBrowse link
G Hrc histidine rich calcium binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936664:3,088,072...3,092,034
Ensembl chrNW_004936664:3,083,602...3,092,308 		JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936794:707,122...994,206
Ensembl chrNW_004936794:707,119...994,778 		JBrowse link
G Nmu neuromedin U involved_in ISO PMID:11853869 UniProt PMID:11853869 RGD:13461753 Ensembl chrNW_004936482:17,936,467...17,961,711 JBrowse link
G Nppa natriuretic peptide A involved_in ISO (PMID:19646991) BHF-UCL PMID:19646991 NCBI chrNW_004936474:671,362...673,610 JBrowse link
G Pde4d phosphodiesterase 4D involved_in ISO PMID:19801680 BHF-UCL PMID:19801680 RGD:7327160 NCBI chrNW_004936480:8,123,437...9,235,586
Ensembl chrNW_004936480:8,204,701...9,234,865 		JBrowse link
G Ptpn1 protein tyrosine phosphatase non-receptor type 1 ISO RGD PMID:22569287 RGD:401976380 NCBI chrNW_004936514:4,065,455...4,083,847
Ensembl chrNW_004936514:4,068,238...4,084,009 		JBrowse link
G Rgs4 regulator of G protein signaling 4 ISO RGD PMID:25844489 RGD:13524517 NCBI chrNW_004937238:101,948...109,513
Ensembl chrNW_004937238:102,061...109,474 		JBrowse link
G Ryr2 ryanodine receptor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12089338)
(PMID:17431507)		 Ensembl
MGI		 PMID:12089338 PMID:17431507 GO_REF:0000107 NCBI chrNW_004936484:15,402,488...15,825,410
Ensembl chrNW_004936484:15,403,819...15,824,441 		JBrowse link
G Scn3b sodium voltage-gated channel beta subunit 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936542:8,082,487...8,106,154
Ensembl chrNW_004936542:8,086,702...8,105,372 		JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 ISO RGD PMID:17259145 RGD:6484226 NCBI chrNW_004936473:27,883,526...27,963,994
Ensembl chrNW_004936473:27,883,526...27,963,994 		JBrowse link
G Sirt1 sirtuin 1 ISO RGD PMID:22113495 RGD:7240568 NCBI chrNW_004936521:10,296,097...10,316,673
Ensembl chrNW_004936521:10,296,097...10,322,215 		JBrowse link
G Slc1a1 solute carrier family 1 member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936503:613,250...690,555
Ensembl chrNW_004936503:613,223...690,721 		JBrowse link
G Trpm4 transient receptor potential cation channel subfamily M member 4 ISO RGD PMID:23954346 RGD:10003031 NCBI chrNW_004936664:3,093,258...3,124,473
Ensembl chrNW_004936664:3,093,367...3,124,117 		JBrowse link
G Uts2 urotensin 2 ISO RGD PMID:12217424 PMID:18597948 RGD:2306810 RGD:2306871 NCBI chrNW_004936623:2,339,259...2,345,717
Ensembl chrNW_004936623:2,340,778...2,345,700 		JBrowse link
positive regulation of heart rate by epinephrine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tpm1 tropomyosin 1 involved_in ISO (MGI:3802907|PMID:17556658) BHF-UCL PMID:17556658 MGI:3802907 NCBI chrNW_004936471:23,643,645...23,670,775
Ensembl chrNW_004936471:23,643,613...23,670,775 		JBrowse link
positive regulation of heart rate by epinephrine-norepinephrine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1a adrenoceptor alpha 1A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12782680) Ensembl
MGI
TreeGrafter		 PMID:12782680 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936757:149,366...237,710
Ensembl chrNW_004936757:150,496...237,710 		JBrowse link
G Adra1b adrenoceptor alpha 1B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12782680) TreeGrafter
MGI		 PMID:12782680 GO_REF:0000118 NCBI chrNW_004936515:3,523,799...3,572,467
Ensembl chrNW_004936515:3,523,797...3,572,596 		JBrowse link
G Adrb1 adrenoceptor beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10358009), (PMID:8693001) Ensembl
MGI
TreeGrafter		 PMID:8693001 PMID:10358009 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936486:4,400,467...4,401,588
Ensembl chrNW_004936486:4,399,915...4,403,149 		JBrowse link
positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10942027) Ensembl
MGI		 PMID:10942027 GO_REF:0000107 NCBI chrNW_004937351:32,324...46,871
Ensembl chrNW_004937351:34,921...47,246 		JBrowse link
positive regulation of the force of heart contraction by epinephrine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb2 adrenoceptor beta 2 ISO RGD PMID:19133992 RGD:5129126 NCBI chrNW_004936504:5,985,407...5,987,453
Ensembl chrNW_004936504:5,985,960...5,987,210 		JBrowse link
positive regulation of the force of heart contraction by epinephrine-norepinephrine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1a adrenoceptor alpha 1A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12595294) Ensembl
MGI		 PMID:12595294 GO_REF:0000107 NCBI chrNW_004936757:149,366...237,710
Ensembl chrNW_004936757:150,496...237,710 		JBrowse link
G Adra1b adrenoceptor alpha 1B acts_upstream_of_or_within ISO (PMID:12595294) MGI PMID:12595294 NCBI chrNW_004936515:3,523,799...3,572,467
Ensembl chrNW_004936515:3,523,797...3,572,596 		JBrowse link
G Adrb1 adrenoceptor beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7761854)
(PMID:8693001)		 Ensembl
MGI		 PMID:7761854 PMID:8693001 GO_REF:0000107 NCBI chrNW_004936486:4,400,467...4,401,588
Ensembl chrNW_004936486:4,399,915...4,403,149 		JBrowse link
positive regulation of the force of heart contraction by norepinephrine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 ISO RGD PMID:19133992 RGD:5129126 NCBI chrNW_004936486:4,400,467...4,401,588
Ensembl chrNW_004936486:4,399,915...4,403,149 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15969
    positive regulation of biological process 6088
      positive regulation of multicellular organismal process 1706
        positive regulation of blood circulation 49
          positive regulation of cerebral blood circulation 1
          positive regulation of gastric mucosal blood circulation 3
          positive regulation of heart contraction + 45
Path 2
Term Annotations click to browse term
  biological_process 15969
    multicellular organismal process 7386
      system process 2585
        circulatory system process 552
          blood circulation 527
            regulation of blood circulation 273
              positive regulation of blood circulation 49
                positive regulation of cerebral blood circulation 1
                positive regulation of gastric mucosal blood circulation 3
                positive regulation of heart contraction + 45
paths to the root