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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of blood circulation
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Accession:GO:1903524 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of blood circulation.
Synonyms:exact_synonym: up regulation of blood circulation;   upregulation of blood circulation
 narrow_synonym: activation of blood circulation
 related_synonym: activation of hemolymph circulation;   positive regulation of hemolymph circulation;   up regulation of hemolymph circulation;   upregulation of hemolymph circulation



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adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pde4d phosphodiesterase 4D involved_in IC PMID:19801680 BHF-UCL PMID:19801680 RGD:7327160 NCBI chr 2:40,014,933...41,529,190
Ensembl chr 2:40,019,933...41,525,884
JBrowse link
positive regulation of cardiac muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace2 angiotensin I converting enzyme 2 involved_in IEA
ISO
GO_REF:0000107
(MGI:2181229|PMID:12075344)
Ensembl
RGD
PMID:12075344 GO_REF:0000107 MGI:2181229 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977
JBrowse link
G Adra1a adrenoceptor alpha 1A involved_in IMP PMID:19011682 BHF-UCL PMID:19011682 RGD:5688340 NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500
JBrowse link
G Ccn2 cellular communication network factor 2 IMP RGD PMID:19707545 RGD:2314476 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
JBrowse link
G Chga chromogranin A involved_in IDA PMID:22459152 UniProt PMID:22459152 RGD:6906968 NCBI chr 6:121,696,051...121,707,399
Ensembl chr 6:121,696,051...121,707,398
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 IEP RGD PMID:21620734 RGD:5686387 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:19646991)
Ensembl
RGD
PMID:19646991 GO_REF:0000107 NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669
JBrowse link
G Nppa natriuretic peptide A involved_in ISO (PMID:19646991) RGD PMID:19646991 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Rgs2 regulator of G-protein signaling 2 involved_in ISO (MGI:3836877|PMID:19127022), (MGI:5009116|PMID:21291891) RGD PMID:19127022 PMID:21291891 MGI:3836877 MGI:5009116 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385
JBrowse link
G Smtn smoothelin acts_upstream_of_or_within ISO MGI:3613292|MGI:3613293 (MGI:4437553|PMID:18678771) RGD PMID:18678771 MGI:4437553 NCBI chr14:78,398,595...78,420,908
Ensembl chr14:78,397,778...78,420,886
JBrowse link
G Ucn urocortin IDA RGD PMID:19460778 RGD:5508168 NCBI chr 6:25,238,120...25,238,950
Ensembl chr 6:25,238,120...25,238,950
JBrowse link
positive regulation of cerebral blood circulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dusp5 dual specificity phosphatase 5 IMP RGD PMID:25397684 RGD:13446412 NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818
JBrowse link
positive regulation of gastric mucosal blood circulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghrl ghrelin and obestatin prepropeptide IDA RGD PMID:17033095 RGD:12910734 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621
JBrowse link
G Ptger2 prostaglandin E receptor 2 IDA RGD PMID:10807413 RGD:10043357 NCBI chr15:18,215,013...18,228,714
Ensembl chr15:18,217,285...18,228,714
JBrowse link
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:10807413 RGD:10043357 NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434
JBrowse link
positive regulation of heart contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb2 adrenoceptor beta 2 IDA RGD PMID:15840637 RGD:1598741 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Apln apelin involved_in IMP PMID:26611206 UniProt PMID:26611206 RGD:11534624 NCBI chr  X:127,180,801...127,213,567
Ensembl chr  X:127,203,823...127,213,391
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 acts_upstream_of_or_within ISO MGI:2451290 (MGI:1337471|PMID:10360172) RGD PMID:10360172 MGI:1337471 NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
JBrowse link
G Glp1r glucagon-like peptide 1 receptor IDA RGD PMID:12093887 RGD:625448 NCBI chr20:8,972,004...9,010,241
Ensembl chr20:8,972,004...9,010,241
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in ISO (MGI:4829580|PMID:20516643) RGD PMID:20516643 MGI:4829580 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802
JBrowse link
G Hrc histidine rich calcium binding protein involved_in ISO UniProtKB:B9EIW1 (PMID:24125847) RGD PMID:24125847 NCBI chr 1:95,813,262...95,816,987
Ensembl chr 1:95,813,253...95,816,984
JBrowse link
G LOC100912649 uncharacterized LOC100912649 involved_in IMP PMID:26611206 UniProt PMID:26611206 RGD:11534624
G Nkx2-5 NK2 homeobox 5 involved_in IEA
ISO
GO_REF:0000107
(MGI:3829107|PMID:18689573)
Ensembl
RGD
PMID:18689573 GO_REF:0000107 MGI:3829107 NCBI chr10:16,340,428...16,347,004
Ensembl chr10:16,344,159...16,346,934
JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:15896309)
AgBase
RGD
PMID:15896309 GO_REF:0000024 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
positive regulation of heart rate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase acts_upstream_of_or_within ISO MGI:1857117|MGI:2681791 (MGI:3653129|PMID:16626672) RGD PMID:16626672 MGI:3653129 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088
JBrowse link
G Adm adrenomedullin involved_in IDA
ISO
(PMID:18434369) RGD PMID:18434369 PMID:19520650 RGD:2325635 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
JBrowse link
G Adra1a adrenoceptor alpha 1A IMP RGD PMID:22040923 RGD:5688308 NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500
JBrowse link
G Adrb1 adrenoceptor beta 1 IMP RGD PMID:9089896 RGD:5129112 NCBI chr 1:255,772,217...255,773,617
Ensembl chr 1:255,771,597...255,807,259
JBrowse link
G Apln apelin IDA RGD PMID:12798955 RGD:1626237 NCBI chr  X:127,180,801...127,213,567
Ensembl chr  X:127,203,823...127,213,391
JBrowse link
G Atp5pf ATP synthase peripheral stalk subunit F6 IDA RGD PMID:12686462 RGD:13800918 NCBI chr11:23,881,594...23,889,581
Ensembl chr11:23,881,592...23,889,119
JBrowse link
G Avpr1a arginine vasopressin receptor 1A IMP RGD PMID:18339407 RGD:2300339 NCBI chr 7:58,114,306...58,118,230
Ensembl chr 7:58,114,284...58,122,215
JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 IMP RGD PMID:20060787 RGD:5130949 NCBI chr 4:84,222,897...84,265,924
Ensembl chr 4:84,224,002...84,265,904
JBrowse link
G Edn1 endothelin 1 involved_in ISO (PMID:2649896) RGD PMID:2649896 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Edn2 endothelin 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:2649896)
Ensembl
RGD
PMID:2649896 GO_REF:0000107 NCBI chr 5:133,751,316...133,756,814
Ensembl chr 5:133,751,217...133,756,814
JBrowse link
G Edn3 endothelin 3 involved_in ISO (PMID:2649896) RGD PMID:2649896 NCBI chr 3:163,562,307...163,586,636
Ensembl chr 3:163,562,520...163,585,093
JBrowse link
G Gch1 GTP cyclohydrolase 1 involved_in ISO (MGI:5629781|PMID:25557619) RGD PMID:25557619 MGI:5629781 NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698
JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 acts_upstream_of_or_within ISO MGI:3574394 (MGI:3574376|PMID:15297376) RGD PMID:15297376 MGI:3574376 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218
JBrowse link
G Hrc histidine rich calcium binding protein involved_in ISO UniProtKB:B9EIW1 (PMID:24125847) RGD PMID:24125847 NCBI chr 1:95,813,262...95,816,987
Ensembl chr 1:95,813,253...95,816,984
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO
IEA
(PMID:19646991)
GO_REF:0000107
RGD
Ensembl
PMID:19646991 GO_REF:0000107 NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669
JBrowse link
G Nmu neuromedin U involved_in IDA PMID:11853869 UniProt PMID:11853869 RGD:13461753 NCBI chr14:31,844,564...31,872,196
Ensembl chr14:31,844,728...31,872,192
JBrowse link
G Nppa natriuretic peptide A involved_in ISO (PMID:19646991) RGD PMID:19646991 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Rgs4 regulator of G-protein signaling 4 IMP RGD PMID:25844489 RGD:13524517 NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068
JBrowse link
G Ryr2 ryanodine receptor 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2183509|MGI:3713774 (MGI:2182484|PMID:12089338), (MGI:3713015|PMID:17431507)
Ensembl
RGD
PMID:12089338 PMID:17431507 GO_REF:0000107 MGI:2182484 MGI:3713015 NCBI chr17:58,389,925...58,975,641
Ensembl chr17:58,389,925...58,975,142
JBrowse link
G Scn3b sodium voltage-gated channel beta subunit 3 involved_in ISO (MGI:5294533|PMID:19796257) RGD PMID:19796257 MGI:5294533 NCBI chr 8:40,630,372...40,652,869
Ensembl chr 8:40,630,455...40,652,868
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 IMP RGD PMID:17259145 RGD:6484226 NCBI chr 8:119,220,905...119,318,816
Ensembl chr 8:119,220,905...119,318,769
JBrowse link
G Sirt1 sirtuin 1 IMP RGD PMID:22113495 RGD:7240568 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Slc1a1 solute carrier family 1 member 1 involved_in ISO (MGI:5584094|PMID:23361868) RGD PMID:23361868 MGI:5584094 NCBI chr 1:226,549,932...226,631,925
Ensembl chr 1:226,549,842...226,630,402
JBrowse link
G Tacr3 tachykinin receptor 3 IDA RGD PMID:2471579 RGD:2305984 NCBI chr 2:223,266,536...223,363,791
Ensembl chr 2:223,266,536...223,363,791
JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 IMP RGD PMID:23954346 RGD:10003031 NCBI chr 1:95,781,805...95,812,095
Ensembl chr 1:95,782,000...95,812,532
JBrowse link
G Uts2 urotensin 2 IDA RGD PMID:18597948 PMID:12217424 RGD:2306810, RGD:2306871 NCBI chr 5:161,450,846...161,456,235
Ensembl chr 5:161,450,846...161,456,237
JBrowse link
positive regulation of heart rate by epinephrine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tpm1 tropomyosin 1 involved_in ISO (MGI:3802907|PMID:17556658) RGD PMID:17556658 MGI:3802907 NCBI chr 8:67,635,479...67,662,330
Ensembl chr 8:67,635,479...67,662,802
JBrowse link
positive regulation of heart rate by epinephrine-norepinephrine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1a adrenoceptor alpha 1A involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:104774 (MGI:2664013|PMID:12782680)
RGD PMID:12782680 PMID:21873635 MGI:2664013, RGD:13792537 NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500
JBrowse link
G Adra1b adrenoceptor alpha 1B involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:104773 (MGI:2664013|PMID:12782680)
RGD PMID:12782680 PMID:21873635 MGI:2664013, RGD:13792537 NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919
JBrowse link
G Adra1d adrenoceptor alpha 1D involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:118,793,356...118,809,354
Ensembl chr 3:118,793,346...118,809,354
JBrowse link
G Adrb1 adrenoceptor beta 1 involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
GO_REF:0000107
MGI:1857120 (MGI:1338641|PMID:10358009), (MGI:82113|PMID:8693001)
PMID:21873635
Ensembl
RGD
PMID:8693001 PMID:10358009 PMID:21873635 GO_REF:0000107 MGI:1338641 MGI:82113, RGD:13792537 NCBI chr 1:255,772,217...255,773,617
Ensembl chr 1:255,771,597...255,807,259
JBrowse link
positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1888407 (MGI:3531222|PMID:10942027)
Ensembl
RGD
PMID:10942027 GO_REF:0000107 MGI:3531222 NCBI chr 1:116,715,286...116,837,223
Ensembl chr 1:116,714,711...116,837,240
JBrowse link
positive regulation of the force of heart contraction by epinephrine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb2 adrenoceptor beta 2 IDA RGD PMID:19133992 RGD:5129126 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
positive regulation of the force of heart contraction by epinephrine-norepinephrine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1a adrenoceptor alpha 1A acts_upstream_of_or_within ISO MGI:104774 (MGI:2656483|PMID:12595294) RGD PMID:12595294 MGI:2656483 NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500
JBrowse link
G Adra1b adrenoceptor alpha 1B acts_upstream_of_or_within ISO MGI:104773 (MGI:2656483|PMID:12595294) RGD PMID:12595294 MGI:2656483 NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919
JBrowse link
G Adrb1 adrenoceptor beta 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857120 (MGI:82113|PMID:8693001), (MGI:84440|PMID:7761854)
Ensembl
RGD
PMID:7761854 PMID:8693001 GO_REF:0000107 MGI:82113 MGI:84440 NCBI chr 1:255,772,217...255,773,617
Ensembl chr 1:255,771,597...255,807,259
JBrowse link
positive regulation of the force of heart contraction by norepinephrine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 IDA RGD PMID:19133992 RGD:5129126 NCBI chr 1:255,772,217...255,773,617
Ensembl chr 1:255,771,597...255,807,259
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    positive regulation of biological process 6686
      positive regulation of multicellular organismal process 1672
        positive regulation of blood circulation 49
          positive regulation of cerebral blood circulation 1
          positive regulation of gastric mucosal blood circulation 3
          positive regulation of heart contraction + 45
Path 2
Term Annotations click to browse term
  biological_process 19497
    multicellular organismal process 8976
      system process 3391
        circulatory system process 589
          blood circulation 560
            regulation of blood circulation 279
              positive regulation of blood circulation 49
                positive regulation of cerebral blood circulation 1
                positive regulation of gastric mucosal blood circulation 3
                positive regulation of heart contraction + 45
paths to the root