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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of blood circulation
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Accession:GO:1903523 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of blood circulation.
Synonyms:exact_synonym: down regulation of blood circulation;   downregulation of blood circulation
 narrow_synonym: inhibition of blood circulation
 related_synonym: down regulation of hemolymph circulation;   downregulation of hemolymph circulation;   inhibition of hemolymph circulation;   negative regulation of hemolymph circulation



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negative regulation of blood circulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGER advanced glycosylation end-product specific receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:1,574,251...1,577,410
Ensembl chr12:1,574,251...1,577,129
JBrowse link
G APP amyloid beta precursor protein involved_in ISO (PMID:12808450)
(MGI:6271381|PMID:12808450)
ARUK-UCL PMID:12808450 MGI:6271381 NCBI chr31:21,351,207...21,614,466
Ensembl chr31:21,351,207...21,614,337
JBrowse link
negative regulation of cardiac muscle cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY10 adenylate cyclase 10 ISO RGD PMID:31754830 RGD:329403060 NCBI chr 7:30,576,445...30,660,926
Ensembl chr 7:30,577,591...30,660,926
JBrowse link
negative regulation of cardiac muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDE5A phosphodiesterase 5A involved_in ISO (MGI:3836877|PMID:19127022) BHF-UCL PMID:19127022 MGI:3836877 NCBI chr32:38,272,573...38,407,517
Ensembl chr32:38,244,338...38,407,522
JBrowse link
G SRI sorcin involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:14,257,375...14,274,816
Ensembl chr14:14,260,052...14,274,801
JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:4,972,369...4,984,218
Ensembl chr15:4,972,956...4,980,371
JBrowse link
negative regulation of heart contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3525392|PMID:15485817) Ensembl
MGI
PMID:15485817 GO_REF:0000107 MGI:3525392 NCBI chr17:53,828,482...53,847,043
Ensembl chr17:53,813,976...53,847,167
JBrowse link
G ATP1A4 ATPase Na+/K+ transporting subunit alpha 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr38:22,023,176...22,080,656
Ensembl chr38:22,023,221...22,080,604
JBrowse link
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1347184|PMID:10555147) Ensembl
MGI
PMID:10555147 GO_REF:0000107 MGI:1347184 NCBI chr26:8,148,181...8,209,392
Ensembl chr26:8,148,236...8,209,388
JBrowse link
G PDE4D phosphodiesterase 4D involved_in ISO (MGI:5442270|PMID:21903937) BHF-UCL PMID:21903937 MGI:5442270 NCBI chr 2:45,843,767...47,245,263
Ensembl chr 2:45,846,294...46,949,912
JBrowse link
G PLN phospholamban involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:87597|PMID:8062415)
(MGI:1347184|PMID:10555147)
Ensembl
MGI
PMID:8062415 PMID:10555147 GO_REF:0000107 MGI:1347184 MGI:87597 NCBI chr 1:58,579,095...58,590,541
Ensembl chr 1:58,579,145...58,590,535
JBrowse link
negative regulation of heart rate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGTR2 angiotensin II receptor type 2 involved_in ISO (MGI:3626025|PMID:9449684) BHF-UCL PMID:9449684 MGI:3626025 NCBI chr  X:88,703,551...88,708,451
Ensembl chr  X:88,705,765...88,706,853
JBrowse link
G FKBP1B FKBP prolyl isomerase 1B involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:18,534,295...18,544,973
Ensembl chr17:18,534,741...18,544,943
JBrowse link
G GJD3 gap junction protein delta 3 involved_in ISO (MGI:3623651|PMID:16571663) BHF-UCL PMID:16571663 MGI:3623651 NCBI chr 9:22,246,891...22,248,597 JBrowse link
G LOC119880472 peptidyl-prolyl cis-trans isomerase FKBP1B involved_in IEA Ensembl GO_REF:0000107
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 ISO RGD PMID:19015400 RGD:4108483 NCBI chr 2:53,447,802...53,527,563
Ensembl chr 2:53,448,286...53,524,970
JBrowse link
G PLN phospholamban involved_in IEA
IBA
Ensembl
TreeGrafter
GO_Central
GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:58,579,095...58,590,541
Ensembl chr 1:58,579,145...58,590,535
JBrowse link
G RNLS renalase, FAD dependent amine oxidase involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:38,137,662...38,413,666
Ensembl chr26:38,083,371...38,414,033
JBrowse link
G SPTBN4 spectrin beta, non-erythrocytic 4 acts_upstream_of_or_within ISO (MGI:4837024|PMID:20877009) MGI PMID:20877009 MGI:4837024 NCBI chr 1:113,167,251...113,243,071
Ensembl chr 1:113,168,484...113,240,934
JBrowse link
G SPX spexin hormone involved_in ISO PMID:22038051 UniProt PMID:22038051 RGD:8693358 NCBI chr27:25,561,636...25,572,310
Ensembl chr27:25,563,606...25,571,093
JBrowse link
G SRI sorcin involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:14,257,375...14,274,816
Ensembl chr14:14,260,052...14,274,801
JBrowse link
G TAC1 tachykinin precursor 1 ISO RGD PMID:2471579 RGD:2305984 NCBI chr14:22,631,106...22,640,283
Ensembl chr14:22,632,642...22,640,258
JBrowse link
G TNF tumor necrosis factor ISO RGD PMID:7875478 RGD:14975128 NCBI chr12:1,074,561...1,076,425
Ensembl chr12:1,074,552...1,076,425
JBrowse link
G TRPV1 transient receptor potential cation channel subfamily V member 1 ISO RGD PMID:27335281 RGD:13792700 NCBI chr 9:47,404,987...47,443,871
Ensembl chr 9:47,404,972...47,431,926
JBrowse link
G UTS2 urotensin 2 ISO RGD PMID:12217424 RGD:2306871 NCBI chr 5:61,503,268...61,508,146 JBrowse link
negative regulation of heart rate by acetylcholine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHRM3 cholinergic receptor muscarinic 3 ISO RGD PMID:9316844 RGD:2303391 NCBI chr 4:504,663...999,550
Ensembl chr 4:506,990...520,613
JBrowse link
negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRA1A adrenoceptor alpha 1A acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2182494|PMID:12093905) MGI
Ensembl
PMID:12093905 GO_REF:0000107 MGI:2182494 NCBI chr25:30,690,959...30,801,484
Ensembl chr25:30,693,571...30,801,486
JBrowse link
negative regulation of the force of heart contraction by chemical signal term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRK2 G protein-coupled receptor kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:50,148,566...50,167,422
Ensembl chr18:50,148,598...50,167,428
JBrowse link
negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRA1D adrenoceptor alpha 1D acts_upstream_of_or_within ISO (MGI:2656483|PMID:12595294) MGI PMID:12595294 MGI:2656483 NCBI chr24:17,231,771...17,239,110
Ensembl chr24:17,213,643...17,214,761
Ensembl chr24:17,213,643...17,214,761
JBrowse link
negative regulation of ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BIN1 bridging integrator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:23,503,934...23,534,407
Ensembl chr19:23,375,363...23,534,303
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17874
    negative regulation of biological process 5723
      negative regulation of multicellular organismal process 1369
        negative regulation of blood circulation 28
          negative regulation of cerebral blood circulation 0
          negative regulation of gastric mucosal blood circulation 0
          negative regulation of heart contraction + 26
Path 2
Term Annotations click to browse term
  biological_process 17874
    multicellular organismal process 8470
      system process 2892
        circulatory system process 599
          blood circulation 572
            regulation of blood circulation 295
              negative regulation of blood circulation 28
                negative regulation of cerebral blood circulation 0
                negative regulation of gastric mucosal blood circulation 0
                negative regulation of heart contraction + 26
paths to the root