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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of blood circulation
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Accession:GO:1903523 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of blood circulation.
Synonyms:exact_synonym: down regulation of blood circulation;   downregulation of blood circulation
 narrow_synonym: inhibition of blood circulation
 related_synonym: down regulation of hemolymph circulation;   downregulation of hemolymph circulation;   inhibition of hemolymph circulation;   negative regulation of hemolymph circulation


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negative regulation of blood circulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGER advanced glycosylation end-product specific receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:31,828,363...31,831,981
Ensembl chr 6:32,708,251...32,711,641 		JBrowse link
G APP amyloid beta precursor protein involved_in ISO (PMID:12808450)
(MGI:6271381|PMID:12808450)		 ARUK-UCL PMID:12808450 MGI:6271381 NCBI chr21:12,324,455...12,608,594
Ensembl chr21:25,684,355...25,995,072 		JBrowse link
negative regulation of cardiac muscle cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY10 adenylate cyclase 10 ISO RGD PMID:31754830 RGD:329403060 NCBI chr 1:143,239,576...143,404,038
Ensembl chr 1:147,023,671...147,129,705 		JBrowse link
negative regulation of cardiac muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDE5A phosphodiesterase 5A involved_in ISO (MGI:3836877|PMID:19127022) BHF-UCL PMID:19127022 MGI:3836877 NCBI chr 4:111,682,772...111,817,234
Ensembl chr 4:122,832,175...122,966,636 		JBrowse link
G SRI sorcin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:80,199,719...80,214,733
Ensembl chr 7:93,850,496...93,864,029 		JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:36,743,341...36,753,261
Ensembl chr 1:38,093,917...38,103,556 		JBrowse link
negative regulation of heart contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15485817) Ensembl
MGI		 PMID:15485817 GO_REF:0000107 NCBI chr 1:86,162,401...86,193,883
Ensembl chr 1:121,212,488...121,243,099 		JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10360172) Ensembl
MGI		 PMID:10360172 GO_REF:0000107 NCBI chr 1:135,469,495...135,497,303
Ensembl chr 1:139,390,549...139,418,303 		JBrowse link
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 acts_upstream_of_or_within ISO (PMID:10555147) MGI PMID:10555147 NCBI chr12:107,857,009...107,924,938
Ensembl chr12:111,246,508...111,311,923 		JBrowse link
G PDE4D phosphodiesterase 4D involved_in ISO (MGI:5442270|PMID:21903937) BHF-UCL PMID:21903937 MGI:5442270 NCBI chr 5:53,510,287...55,039,181
Ensembl chr 5:55,749,214...56,670,111 		JBrowse link
G PLN phospholamban involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8062415)
(PMID:10555147)		 Ensembl
MGI		 PMID:8062415 PMID:10555147 GO_REF:0000107 NCBI chr 6:116,357,335...116,370,382
Ensembl chr 6:120,509,510...120,509,668 		JBrowse link
negative regulation of heart rate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGTR2 angiotensin II receptor type 2 involved_in ISO (MGI:3626025|PMID:9449684) BHF-UCL PMID:9449684 MGI:3626025 NCBI chr  X:105,252,903...105,257,171
Ensembl chr  X:115,671,594...115,672,685 		JBrowse link
G FKBP1B FKBP prolyl isomerase 1B involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:24,047,287...24,065,765
Ensembl chr2A:24,145,893...24,159,082 		JBrowse link
G GJD3 gap junction protein delta 3 involved_in ISO (MGI:3623651|PMID:16571663) BHF-UCL PMID:16571663 MGI:3623651 NCBI chr17:16,925,395...16,929,683 JBrowse link
G NPFF neuropeptide FF-amide peptide precursor ISO RGD PMID:8680863 RGD:2316573 NCBI chr12:35,245,172...35,246,710
Ensembl chr12:36,030,805...36,031,591 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 ISO RGD PMID:19015400 RGD:4108483 NCBI chr 5:45,701,219...45,786,652
Ensembl chr 5:47,267,286...47,350,960 		JBrowse link
G PLN phospholamban involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:116,357,335...116,370,382
Ensembl chr 6:120,509,510...120,509,668 		JBrowse link
G RNLS renalase, FAD dependent amine oxidase involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:84,996,999...85,304,240
Ensembl chr10:88,503,683...88,808,990 		JBrowse link
G SPTBN4 spectrin beta, non-erythrocytic 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20877009) Ensembl
MGI		 PMID:20877009 GO_REF:0000107 NCBI chr19:37,515,420...37,621,473
Ensembl chr19:46,042,387...46,127,429 		JBrowse link
G SPX spexin hormone involved_in ISO PMID:22038051 UniProt PMID:22038051 RGD:8693358 NCBI chr12:64,766,136...64,771,728
Ensembl chr12:67,369,413...67,375,630 		JBrowse link
G SRI sorcin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:80,199,719...80,214,733
Ensembl chr 7:93,850,496...93,864,029 		JBrowse link
G TAC1 tachykinin precursor 1 ISO RGD PMID:2471579 RGD:2305984 NCBI chr 7:89,675,834...89,684,391
Ensembl chr 7:103,257,501...103,266,389 		JBrowse link
G TNF tumor necrosis factor ISO RGD PMID:7875478 RGD:14975128 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381 		JBrowse link
G TRPV1 transient receptor potential cation channel subfamily V member 1 ISO RGD PMID:27335281 RGD:13792700 NCBI chr17:3,612,781...3,658,608
Ensembl chr17:3,609,952...3,637,579 		JBrowse link
G UTS2 urotensin 2 ISO RGD PMID:12217424 RGD:2306871 NCBI chr 1:6,609,104...6,616,966
Ensembl chr 1:7,854,687...7,864,688 		JBrowse link
negative regulation of heart rate by acetylcholine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHRM3 cholinergic receptor muscarinic 3 ISO RGD PMID:9316844 RGD:2303391 NCBI chr 1:214,931,514...215,452,739 JBrowse link
negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRA1A adrenoceptor alpha 1A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12093905) Ensembl
MGI		 PMID:12093905 GO_REF:0000107 NCBI chr 8:25,947,996...26,138,022
Ensembl chr 8:22,853,677...23,044,388 		JBrowse link
negative regulation of the force of heart contraction by chemical signal term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRK2 G protein-coupled receptor kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:62,624,647...62,644,846
Ensembl chr11:65,939,164...65,959,066 		JBrowse link
negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRA1D adrenoceptor alpha 1D acts_upstream_of_or_within ISO (PMID:12595294) MGI PMID:12595294 NCBI chr20:4,242,788...4,271,295
Ensembl chr20:4,040,888...4,068,018 		JBrowse link
negative regulation of ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BIN1 bridging integrator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:33,168,767...33,228,075
Ensembl chr2B:127,716,550...127,775,378 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16313
    negative regulation of biological process 5460
      negative regulation of multicellular organismal process 1227
        negative regulation of blood circulation 28
          negative regulation of cerebral blood circulation 0
          negative regulation of gastric mucosal blood circulation 0
          negative regulation of heart contraction + 26
Path 2
Term Annotations click to browse term
  biological_process 16313
    multicellular organismal process 7188
      system process 2187
        circulatory system process 571
          blood circulation 544
            regulation of blood circulation 277
              negative regulation of blood circulation 28
                negative regulation of cerebral blood circulation 0
                negative regulation of gastric mucosal blood circulation 0
                negative regulation of heart contraction + 26
paths to the root