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ONTOLOGY REPORT - ANNOTATIONS


Term:mucopolysaccharide metabolic process
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Accession:GO:1903510 term browser browse the term
Definition:The chemical reactions and pathways involving mucopolysaccharide.
Synonyms:exact_synonym: mucopolysaccharide metabolism



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chondroitin sulfate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07047835.1 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 Ensembl chr 5:48,925,362...48,927,475 JBrowse link
G B4galnt3 beta-1,4-N-acetyl-galactosaminyl transferase 3 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 4:153,409,019...153,509,019
Ensembl chr 4:153,409,004...153,509,321
JBrowse link
G B4galnt4 beta-1,4-N-acetyl-galactosaminyl transferase 4 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 1:196,171,394...196,182,294
Ensembl chr 1:196,171,394...196,182,294
JBrowse link
G Chpf chondroitin polymerizing factor involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:12761225)
MGI:2681120|MGI:5464019 (PMID:22952769), (PMID:22952873)
MGI:1926173|MGI:2681120 (PMID:17253960), (PMID:22952769)
GO_REF:0000033
RGD
GO_Central
PMID:12761225 PMID:17253960 PMID:22952769 PMID:22952873 GO_REF:0000033 NCBI chr 9:76,963,178...76,967,878
Ensembl chr 9:76,963,184...76,967,878
JBrowse link
G Chpf2 chondroitin polymerizing factor 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:10,578,470...10,585,940
Ensembl chr 4:10,580,462...10,585,916
JBrowse link
G Chst11 carbohydrate sulfotransferase 11 involved_in
acts_upstream_of_or_within
ISO
IEA
(PMID:11056388)
MGI:1926002 (PMID:10722746), (PMID:21138417)
GO_REF:0000107
RGD
Ensembl
PMID:10722746 PMID:11056388 PMID:21138417 GO_REF:0000107 NCBI chr 7:20,524,535...20,743,008
Ensembl chr 7:20,528,100...20,743,111
JBrowse link
G Chst12 carbohydrate sulfotransferase 12 involved_in ISO (PMID:10781601) RGD PMID:10781601 NCBI chr12:14,110,631...14,129,099
Ensembl chr12:14,110,393...14,129,057
JBrowse link
G Chst13 carbohydrate sulfotransferase 13 involved_in ISO (PMID:12080076) RGD PMID:12080076 NCBI chr 4:122,824,022...122,837,940
Ensembl chr 4:122,824,022...122,838,019
JBrowse link
G Chst3 carbohydrate sulfotransferase 3 acts_upstream_of_or_within
involved_in
IDA
ISO
IBA
IEA
ISS
MGI:2176247 (PMID:11696535), (PMID:9597547)
(PMID:9597547)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024
(PMID:15215498), (PMID:9883891)
RGD
GO_Central
Ensembl
UniProt
PMID:9597547 PMID:9883891 PMID:11696535 PMID:15215498 PMID:16495484 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107, RGD:1600854 NCBI chr20:28,114,386...28,152,046
Ensembl chr20:28,114,404...28,121,807
JBrowse link
G Chst7 carbohydrate sulfotransferase 7 involved_in ISO
IBA
(PMID:10781596)
GO_REF:0000033
RGD
GO_Central
PMID:10781596 GO_REF:0000033 NCBI chr  X:2,396,260...2,432,828
Ensembl chr  X:2,393,874...2,432,840
JBrowse link
G Chsy1 chondroitin sulfate synthase 1 acts_upstream_of_or_within
involved_in
ISO
IBA
(PMID:11514575)
MGI:106576 (PMID:22952769)
GO_REF:0000033
RGD
GO_Central
PMID:11514575 PMID:22952769 GO_REF:0000033 NCBI chr 1:119,689,626...119,750,711
Ensembl chr 1:119,686,350...119,750,601
JBrowse link
G Chsy3 chondroitin sulfate synthase 3 involved_in IBA
ISO
GO_REF:0000033
MGI:106576 (PMID:17253960)
GO_Central
RGD
PMID:17253960 GO_REF:0000033 NCBI chr18:52,644,356...52,901,257
Ensembl chr18:52,644,461...52,898,098
JBrowse link
G Csgalnact1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 involved_in ISO
IBA
(PMID:11514575), (PMID:12163485)
MGI:1926002|MGI:4868209 (PMID:17145758), (PMID:25568321), (PMID:29287114)
GO_REF:0000033
RGD
GO_Central
PMID:11514575 PMID:12163485 PMID:17145758 PMID:25568321 PMID:29287114 GO_REF:0000033 NCBI chr16:20,995,210...21,330,586
Ensembl chr16:21,235,784...21,330,319
JBrowse link
G Csgalnact2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 involved_in IBA
ISO
GO_REF:0000033
(PMID:25568321)
GO_Central
RGD
PMID:25568321 GO_REF:0000033 NCBI chr 4:151,271,774...151,308,856
Ensembl chr 4:151,277,645...151,308,839
JBrowse link
G Slc35b2 solute carrier family 35 member B2 involved_in ISO (PMID:35325049) RGD PMID:35325049 NCBI chr 9:15,438,594...15,442,227
Ensembl chr 9:15,438,594...15,442,234
JBrowse link
G Slc35d1 solute carrier family 35 member D1 acts_upstream_of_or_within ISO MGI:3774133 (PMID:17952091) RGD PMID:17952091 NCBI chr 5:117,928,628...117,981,289
Ensembl chr 5:117,934,352...117,981,311
JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:2675908|PMID:14505572)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:14505572 GO_REF:0000024 GO_REF:0000107 MGI:2675908 NCBI chr14:42,848,704...42,872,351
Ensembl chr14:42,848,854...42,872,354
JBrowse link
G Xylt1 xylosyltransferase 1 involved_in IEA
ISO
GO_REF:0000041
(MGI:5544658|PMID:24161523)
UniProt
RGD
PMID:24161523 GO_REF:0000041 MGI:5544658 NCBI chr 1:171,643,925...171,929,774
Ensembl chr 1:171,643,925...171,926,783
JBrowse link
G Xylt2 xylosyltransferase 2 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr10:79,605,910...79,619,482
Ensembl chr10:79,606,007...79,619,391
JBrowse link
chondroitin sulfate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gusb glucuronidase, beta involved_in ISO MGI:1856041 (PMID:23897660) RGD PMID:23897660 NCBI chr12:26,701,188...26,714,718
Ensembl chr12:26,697,951...26,726,905
JBrowse link
G Hexb hexosaminidase subunit beta involved_in IEA
ISO
GO_REF:0000107
MGI:2429701 (PMID:22451654)
Ensembl
RGD
PMID:22451654 GO_REF:0000107 NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223
JBrowse link
G Hyal1 hyaluronidase 1 involved_in IEA
ISO
GO_REF:0000107
MGI:2658730 (PMID:22451654)
Ensembl
RGD
PMID:22451654 GO_REF:0000107 NCBI chr 8:108,250,668...108,254,519
Ensembl chr 8:108,250,667...108,260,210
JBrowse link
G Hyal4 hyaluronidase 4 acts_upstream_of_or_within ISO (PMID:23086929) RGD PMID:23086929 NCBI chr 4:53,256,179...53,274,819
Ensembl chr 4:53,256,179...53,274,819
JBrowse link
chondroitin sulfate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bpnt2 3'(2'), 5'-bisphosphate nucleotidase 2 acts_upstream_of_or_within ISO MGI:3806990|MGI:3810994 (PMID:18539921), (PMID:18695242) RGD PMID:18539921 PMID:18695242 NCBI chr 5:17,775,684...17,802,570
Ensembl chr 5:17,772,608...17,802,570
JBrowse link
G Chst11 carbohydrate sulfotransferase 11 acts_upstream_of_or_within ISO MGI:3768254 (PMID:16079159) RGD PMID:16079159 NCBI chr 7:20,524,535...20,743,008
Ensembl chr 7:20,528,100...20,743,111
JBrowse link
G Csgalnact1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 acts_upstream_of_or_within ISO MGI:4868209|MGI:4947395 (PMID:20812917), (PMID:21148564) RGD PMID:20812917 PMID:21148564 NCBI chr16:20,995,210...21,330,586
Ensembl chr16:21,235,784...21,330,319
JBrowse link
G Dse dermatan sulfate epimerase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:26,118,194...26,196,889
Ensembl chr20:26,118,196...26,196,992
JBrowse link
G Dsel dermatan sulfate epimerase-like involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:5583872 (PMID:22496542)
GO_Central
RGD
PMID:22496542 GO_REF:0000033 NCBI chr13:186,413...192,592
Ensembl chr13:175,805...192,647
JBrowse link
G Ext1 exostosin glycosyltransferase 1 acts_upstream_of_or_within ISO (PMID:32201365) RGD PMID:32201365 NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357
JBrowse link
dermatan sulfate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chst12 carbohydrate sulfotransferase 12 involved_in ISO (PMID:10781601) RGD PMID:10781601 NCBI chr12:14,110,631...14,129,099
Ensembl chr12:14,110,393...14,129,057
JBrowse link
G Chst14 carbohydrate sulfotransferase 14 acts_upstream_of_or_within ISO (PMID:11470797) RGD PMID:11470797 NCBI chr 3:105,916,481...105,918,538
Ensembl chr 3:105,916,466...105,918,548
JBrowse link
G Dse dermatan sulfate epimerase involved_in ISO (PMID:16505484) RGD PMID:16505484 NCBI chr20:26,118,194...26,196,889
Ensembl chr20:26,118,196...26,196,992
JBrowse link
dermatan sulfate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arsb arylsulfatase B involved_in ISO MGI:3800577 (PMID:24240681) RGD PMID:24240681 NCBI chr 2:25,002,210...25,162,675
Ensembl chr 2:25,002,346...25,162,671
JBrowse link
G Hexa hexosaminidase subunit alpha involved_in ISO MGI:96074 (PMID:11707436) RGD PMID:11707436 NCBI chr 8:59,936,526...59,961,654
Ensembl chr 8:59,936,660...59,962,013
JBrowse link
G Hexb hexosaminidase subunit beta involved_in IEA
ISO
GO_REF:0000107
MGI:96073 (PMID:11707436)
Ensembl
RGD
PMID:11707436 GO_REF:0000107 NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223
JBrowse link
G Ids iduronate 2-sulfatase involved_in ISO MGI:5439833 (PMID:30064964) RGD PMID:30064964 NCBI chr  X:149,025,976...149,046,641
Ensembl chr  X:149,025,976...149,046,663
JBrowse link
G Idua alpha-L-iduronidase involved_in
acts_upstream_of_or_within
ISO (PMID:24036510)
MGI:2176236|MGI:4415188 (PMID:19751987), (PMID:25854773)
MGI:2176236|MGI:4415188 (PMID:19751987), (PMID:19834056)
RGD PMID:19751987 PMID:19834056 PMID:24036510 PMID:25854773 NCBI chr14:1,031,588...1,059,494
Ensembl chr14:1,032,171...1,046,522
JBrowse link
dermatan sulfate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dse dermatan sulfate epimerase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:26,118,194...26,196,889
Ensembl chr20:26,118,196...26,196,992
JBrowse link
G Dsel dermatan sulfate epimerase-like involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:5583872 (PMID:22496542)
GO_Central
RGD
PMID:22496542 GO_REF:0000033 NCBI chr13:186,413...192,592
Ensembl chr13:175,805...192,647
JBrowse link
heparin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angpt1 angiopoietin 1 involved_in ISO
IEA
(PMID:19297368)
GO_REF:0000107
RGD
Ensembl
PMID:19297368 GO_REF:0000107 NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067
JBrowse link
G Ext1 exostosin glycosyltransferase 1 acts_upstream_of_or_within
acts_upstream_of_or_within_positive_effect
ISO MGI:108050 (PMID:21148566), (PMID:21310272)
(PMID:10926768), (PMID:15161920), (PMID:15177029), (PMID:18480751)
RGD PMID:10926768 PMID:15161920 PMID:15177029 PMID:18480751 PMID:21148566 More... NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357
JBrowse link
G Ext2 exostosin glycosyltransferase 2 acts_upstream_of_or_within ISO MGI:894663 (PMID:21310272) RGD PMID:21310272 NCBI chr 3:79,665,414...79,798,077
Ensembl chr 3:79,665,415...79,798,059
JBrowse link
G Glce glucuronic acid epimerase involved_in IEA
ISO
GO_REF:0000041
(MGI:2135754|PMID:11279150)
UniProt
RGD
PMID:11279150 GO_REF:0000041 MGI:2135754 NCBI chr 8:62,546,104...62,612,144
Ensembl chr 8:62,546,107...62,612,040
JBrowse link
G Ndst1 N-deacetylase and N-sulfotransferase 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr18:54,136,887...54,199,545
Ensembl chr18:54,140,779...54,178,191
JBrowse link
G Ndst2 N-deacetylase and N-sulfotransferase 2 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr15:3,563,515...3,573,801
Ensembl chr15:3,563,358...3,573,801
JBrowse link
G Ndst3 N-deacetylase and N-sulfotransferase 3 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 2:211,702,728...211,868,159
Ensembl chr 2:211,704,898...211,854,584
JBrowse link
G Ndst4 N-deacetylase and N-sulfotransferase 4 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 2:213,787,010...214,119,514
Ensembl chr 2:213,787,006...214,115,373
JBrowse link
G Slc10a7 solute carrier family 10, member 7 involved_in ISO (PMID:30082715)
(MGI:6198941|PMID:30082715)
RGD PMID:30082715 MGI:6198941 NCBI chr19:29,183,143...29,407,470
Ensembl chr19:29,183,155...29,407,464
JBrowse link
G Xylt2 xylosyltransferase 2 acts_upstream_of_or_within ISO MGI:3714171 (PMID:17517600) RGD PMID:17517600 NCBI chr10:79,605,910...79,619,482
Ensembl chr10:79,606,007...79,619,391
JBrowse link
heparin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idua alpha-L-iduronidase acts_upstream_of_or_within ISO (PMID:21873421)
MGI:2176236|MGI:4415188 (PMID:19751987), (PMID:19834056), (PMID:21873421)
RGD PMID:19751987 PMID:19834056 PMID:21873421 NCBI chr14:1,031,588...1,059,494
Ensembl chr14:1,032,171...1,046,522
JBrowse link
heparin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ednra endothelin receptor type A involved_in IEA
ISO
GO_REF:0000107
MGI:102720|MGI:105923 (PMID:27026367)
Ensembl
RGD
PMID:27026367 GO_REF:0000107 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
JBrowse link
G Ednrb endothelin receptor type B involved_in ISO MGI:102720|MGI:105923 (PMID:27026367) RGD PMID:27026367 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115
JBrowse link
G Ext1 exostosin glycosyltransferase 1 acts_upstream_of_or_within ISO (PMID:26491162), (PMID:32201365) RGD PMID:26491162 PMID:32201365 NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357
JBrowse link
G Hpse heparanase involved_in IEA
ISO
GO_REF:0000107
(PMID:27026367)
Ensembl
RGD
PMID:27026367 GO_REF:0000107 NCBI chr14:8,896,593...8,937,011
Ensembl chr14:8,896,593...8,937,010
JBrowse link
G Hs2st1 heparan sulfate 2-O-sulfotransferase 1 acts_upstream_of_or_within ISO MGI:1934916 (PMID:11457822) RGD PMID:11457822 NCBI chr 2:233,508,018...233,641,769
Ensembl chr 2:233,508,021...233,641,769
JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase acts_upstream_of_or_within ISO MGI:1934018 (PMID:12111813), (PMID:25267636), (PMID:29624734) RGD PMID:12111813 PMID:25267636 PMID:29624734 NCBI chr10:86,001,545...86,009,049
Ensembl chr10:86,001,566...86,008,972
JBrowse link
hyaluronan biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc5 ATP binding cassette subfamily C member 5 involved_in IEA
ISO
GO_REF:0000107
(PMID:17540771)
Ensembl
RGD
PMID:17540771 GO_REF:0000107 NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253
JBrowse link
G Ccnd3 cyclin D3 IMP RGD PMID:19276076 RGD:2316018 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
JBrowse link
G Has1 hyaluronan synthase 1 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:10455188), (PMID:8626618)
(PMID:10617644)
GO_Central
RGD
PMID:8626618 PMID:10455188 PMID:10617644 GO_REF:0000033 NCBI chr 1:58,693,411...58,705,653
Ensembl chr 1:58,693,411...58,705,397
JBrowse link
G Has2 hyaluronan synthase 2 involved_in IEP
ISO
IBA
IEA
PMID:19635555
(MGI:1861536|PMID:10930438), (PMID:10455188), (PMID:8798545)
GO_REF:0000033
(PMID:17324121), (PMID:20507985), (PMID:22016393), (PMID:30394292)
GO_REF:0000041
RGD
GO_Central
UniProt
PMID:8798545 PMID:10455188 PMID:10930438 PMID:17324121 PMID:20507985 More... GO_REF:0000033 GO_REF:0000041 MGI:1861536, RGD:8553259 NCBI chr 7:88,113,326...88,139,337
Ensembl chr 7:88,113,326...88,128,933
JBrowse link
G Has3 hyaluronan synthase 3 involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:16900089)
(PMID:9060470)
(PMID:10455188)
GO_REF:0000033
RGD
GO_Central
PMID:9060470 PMID:10455188 PMID:16900089 GO_REF:0000033 NCBI chr19:34,768,421...34,782,170
Ensembl chr19:34,771,982...34,782,592
JBrowse link
G Hyal1 hyaluronidase 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:21829529)
UniProt
Ensembl
RGD
PMID:21829529 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:108,250,668...108,254,519
Ensembl chr 8:108,250,667...108,260,210
JBrowse link
G Il1b interleukin 1 beta involved_in ISO (PMID:15100360) RGD PMID:15100360 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
hyaluronan catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd44 CD44 molecule involved_in ISO
IEA
(PMID:17170110)
GO_REF:0000107
(PMID:26528478)
RGD
Ensembl
PMID:17170110 PMID:26528478 GO_REF:0000107 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cemip cell migration inducing hyaluronidase 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5545862|PMID:24251095)
(PMID:23509262)
UniProt
RGD
PMID:23509262 PMID:24251095 GO_REF:0000024 MGI:5545862 NCBI chr 1:137,906,921...138,062,430
Ensembl chr 1:137,908,920...138,062,415
JBrowse link
G Cemip2 cell migration inducing hyaluronidase 2 involved_in ISO (MGI:6810380|PMID:34624311) RGD PMID:34624311 MGI:6810380 NCBI chr 1:219,330,295...219,407,760
Ensembl chr 1:219,337,985...219,407,760
JBrowse link
G Fgf2 fibroblast growth factor 2 involved_in ISO (PMID:19577615) RGD PMID:19577615 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Gusb glucuronidase, beta involved_in ISO (PMID:20385825) RGD PMID:20385825 NCBI chr12:26,701,188...26,714,718
Ensembl chr12:26,697,951...26,726,905
JBrowse link
G Hexa hexosaminidase subunit alpha involved_in ISO MGI:2429698 (PMID:22451654) RGD PMID:22451654 NCBI chr 8:59,936,526...59,961,654
Ensembl chr 8:59,936,660...59,962,013
JBrowse link
G Hexb hexosaminidase subunit beta involved_in IEA
ISO
GO_REF:0000107
MGI:2429701 (PMID:22451654)
Ensembl
RGD
PMID:22451654 GO_REF:0000107 NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223
JBrowse link
G Hmmr hyaluronan-mediated motility receptor involved_in ISO (PMID:26528478) RGD PMID:26528478 NCBI chr10:25,132,933...25,163,029
Ensembl chr10:25,132,977...25,163,060
JBrowse link
G Hyal1 hyaluronidase 1 involved_in ISO
IBA
IEA
(PMID:12084718)
MGI:2658730 (PMID:22451654), (PMID:26887442)
GO_REF:0000033
GO_REF:0000118
GO_REF:0000107
(PMID:11296287), (PMID:17170110), (PMID:20473947), (PMID:21695196), (PMID:21699545), (PMID:21829529)
RGD
GO_Central
TreeGrafter
Ensembl
PMID:11296287 PMID:12084718 PMID:17170110 PMID:20473947 PMID:21695196 More... GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:108,250,668...108,254,519
Ensembl chr 8:108,250,667...108,260,210
JBrowse link
G Hyal2 hyaluronidase 2 involved_in IDA
ISO
IBA
IEA
PMID:19635555
MGI:3836764 (PMID:23172227), (PMID:26887442)
GO_REF:0000033
GO_REF:0000107
(PMID:17170110), (PMID:19443707), (PMID:20554532), (PMID:21699545)
RGD
GO_Central
Ensembl
PMID:17170110 PMID:19443707 PMID:20554532 PMID:21699545 PMID:23172227 More... GO_REF:0000033 GO_REF:0000107, RGD:8553259 NCBI chr 8:108,241,895...108,246,853
Ensembl chr 8:108,243,133...108,246,850
JBrowse link
G Hyal3 hyaluronidase 3 involved_in ISS
IBA
IEA
ISO
GO_REF:0000024
GO_REF:0000033
GO_REF:0000118
GO_REF:0000002
(MGI:4834982|PMID:20586096)
(PMID:21699545)
(PMID:12084718)
UniProt
GO_Central
TreeGrafter
InterPro
RGD
PMID:12084718 PMID:20586096 PMID:21699545 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 MGI:4834982 NCBI chr 8:108,254,385...108,260,020
Ensembl chr 8:108,250,667...108,260,647
JBrowse link
G Hyal4 hyaluronidase 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:53,256,179...53,274,819
Ensembl chr 4:53,256,179...53,274,819
JBrowse link
G Hyal5 hyaluronoglucosaminidase 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:53,341,105...53,412,280
Ensembl chr 4:53,343,475...53,370,785
JBrowse link
G Hyal6 hyaluronoglucosaminidase 6 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:53,238,118...53,250,783
Ensembl chr 4:53,237,983...53,250,783
JBrowse link
G Lyve1 lymphatic vessel endothelial hyaluronan receptor 1 involved_in ISO (PMID:11278811) RGD PMID:11278811 NCBI chr 1:164,962,872...164,976,309
Ensembl chr 1:164,962,872...164,976,309
JBrowse link
G Spam1 sperm adhesion molecule 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:53,302,745...53,312,913
Ensembl chr 4:53,302,745...53,312,908
JBrowse link
G Stab2 stabilin 2 involved_in IEA
ISO
GO_REF:0000107
MGI:5318244 (PMID:22371575)
Ensembl
RGD
PMID:22371575 GO_REF:0000107 NCBI chr 7:21,249,426...21,433,051
Ensembl chr 7:21,249,391...21,434,042
JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO
ISS
(PMID:17324121)
GO_REF:0000024
RGD
UniProt
PMID:17324121 GO_REF:0000024 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
hyaluronan metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cemip cell migration inducing hyaluronidase 1 involved_in ISO (PMID:28189611), (PMID:28284715) RGD PMID:28189611 PMID:28284715 NCBI chr 1:137,906,921...138,062,430
Ensembl chr 1:137,908,920...138,062,415
JBrowse link
G Has2 hyaluronan synthase 2 acts_upstream_of_or_within ISO MGI:2176070|MGI:4360705 (PMID:21246657) RGD PMID:21246657 NCBI chr 7:88,113,326...88,139,337
Ensembl chr 7:88,113,326...88,128,933
JBrowse link
G Hyal1 hyaluronidase 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:19478093)
UniProt
RGD
PMID:19478093 GO_REF:0000024 NCBI chr 8:108,250,668...108,254,519
Ensembl chr 8:108,250,667...108,260,210
JBrowse link
G Il15 interleukin 15 IDA RGD PMID:17667861 RGD:5013835 NCBI chr19:25,640,025...25,706,818
Ensembl chr19:25,640,251...25,706,820
JBrowse link
G Itih1 inter-alpha trypsin inhibitor, heavy chain 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr16:6,122,246...6,136,363
Ensembl chr16:6,122,248...6,136,363
JBrowse link
G Itih2 inter-alpha-trypsin inhibitor heavy chain 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr17:68,375,574...68,411,849
Ensembl chr17:68,375,567...68,411,841
JBrowse link
G Itih3 inter-alpha trypsin inhibitor, heavy chain 3 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr16:6,101,922...6,117,154
Ensembl chr16:6,101,930...6,116,924
JBrowse link
G Itih5 inter-alpha-trypsin inhibitor heavy chain 5 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr17:68,248,115...68,352,216
Ensembl chr17:68,252,128...68,352,207
JBrowse link
G Itih6 inter-alpha-trypsin inhibitor heavy chain family member 6 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr  X:19,753,322...19,790,381
Ensembl chr  X:19,753,625...19,789,500
JBrowse link
G Tnfaip6 TNF alpha induced protein 6 involved_in ISO (PMID:20463016), (PMID:26468290) RGD PMID:20463016 PMID:26468290 NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649
JBrowse link
keratan sulfate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3gnt7 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 involved_in ISO
ISS
(PMID:17690104)
(MGI:6151274|PMID:29625490)
GO_REF:0000024
RGD
UniProt
PMID:17690104 PMID:29625490 GO_REF:0000024 MGI:6151274 NCBI chr 9:86,956,220...86,960,171
Ensembl chr 9:86,956,220...86,960,170
JBrowse link
G B4galt4 beta-1,4-galactosyltransferase 4 involved_in ISO
ISS
(PMID:17690104), (PMID:32827291)
GO_REF:0000024
RGD
UniProt
PMID:17690104 PMID:32827291 GO_REF:0000024 NCBI chr11:61,995,807...62,021,751
Ensembl chr11:61,995,814...62,021,671
JBrowse link
G Chst1 carbohydrate sulfotransferase 1 involved_in ISO
ISS
(PMID:17690104)
GO_REF:0000024
RGD
UniProt
PMID:17690104 GO_REF:0000024 NCBI chr 3:78,552,059...78,574,740
Ensembl chr 3:78,548,525...78,574,883
JBrowse link
G Chst4 carbohydrate sulfotransferase 4 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr19:37,993,471...38,002,123
Ensembl chr19:37,991,417...38,003,608
JBrowse link
G Chst5 carbohydrate sulfotransferase 5 involved_in ISO
IBA
(MGI:1934540|PMID:11278593)
GO_REF:0000033
(PMID:11278593), (PMID:17690104)
RGD
GO_Central
PMID:11278593 PMID:17690104 GO_REF:0000033 MGI:1934540 NCBI chr19:39,860,729...39,881,019
Ensembl chr19:39,860,501...39,881,064
JBrowse link
keratan sulfate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gns glucosamine (N-acetyl)-6-sulfatase IDA RGD PMID:3161730 RGD:1600571 NCBI chr 7:56,889,148...56,923,173
Ensembl chr 7:56,889,232...56,923,151
JBrowse link
keratan sulfate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chst1 carbohydrate sulfotransferase 1 involved_in ISO
IBA
(PMID:9405439)
GO_REF:0000033
RGD
GO_Central
PMID:9405439 GO_REF:0000033 NCBI chr 3:78,552,059...78,574,740
Ensembl chr 3:78,548,525...78,574,883
JBrowse link
negative regulation of hyaluronan biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap2a1 adaptor related protein complex 2 subunit alpha 1 involved_in ISO (PMID:23509262), (PMID:24251095) RGD PMID:23509262 PMID:24251095 NCBI chr 1:95,384,306...95,414,170
Ensembl chr 1:95,384,309...95,414,147
JBrowse link
G Cltc clathrin heavy chain involved_in ISO
ISS
IEA
(PMID:23509262), (PMID:24251095)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:23509262 PMID:24251095 GO_REF:0000024 GO_REF:0000107 NCBI chr10:71,517,661...71,574,591
Ensembl chr10:71,517,663...71,573,737
JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1856877 (PMID:22383528)
Ensembl
RGD
PMID:22383528 GO_REF:0000107 NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749
JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO
ISS
(PMID:17324121)
GO_REF:0000024
RGD
UniProt
PMID:17324121 GO_REF:0000024 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
positive regulation of hyaluronan biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egf epidermal growth factor involved_in ISO
IEA
(PMID:17324121)
GO_REF:0000107
RGD
Ensembl
PMID:17324121 GO_REF:0000107 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Has2 hyaluronan synthase 2 IDA
IMP
RGD PMID:12186949 PMID:17080198 RGD:9588629, RGD:9588632 NCBI chr 7:88,113,326...88,139,337
Ensembl chr 7:88,113,326...88,128,933
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 involved_in ISO
IEA
(PMID:17324121)
GO_REF:0000107
RGD
Ensembl
PMID:17324121 GO_REF:0000107 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in ISO
IEA
ISS
(PMID:17324121)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:17324121 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
JBrowse link
G Ptger4 prostaglandin E receptor 4 IMP RGD PMID:17080198 RGD:9588632 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670
JBrowse link
regulation of hyaluronan biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smpd3 sphingomyelin phosphodiesterase 3 acts_upstream_of_or_within ISO MGI:1856877 (PMID:22383528) RGD PMID:22383528 NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20292
    metabolic process 11720
      organic substance metabolic process 11221
        macromolecule metabolic process 9473
          aminoglycan metabolic process 120
            glycosaminoglycan metabolic process 104
              mucopolysaccharide metabolic process 84
                chondroitin sulfate metabolic process + 27
                dermatan sulfate metabolic process + 9
                heparin metabolic process + 16
                hyaluronan metabolic process + 38
                keratan sulfate metabolic process + 6
paths to the root