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ONTOLOGY REPORT - ANNOTATIONS

Term:mucopolysaccharide metabolic process
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Accession:GO:1903510 term browser browse the term
Definition:The chemical reactions and pathways involving mucopolysaccharide.
Synonyms:exact_synonym: mucopolysaccharide metabolism


show annotations for term's descendants           Sort by:
 
chondroitin sulfate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chpf chondroitin polymerizing factor involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:1926173|MGI:2681120 (MGI:5462286|PMID:22952769), (MGI:7266375|PMID:17253960)
MGI:2681120|MGI:5464019 (MGI:5462280|PMID:22952873), (MGI:5462286|PMID:22952769)
(PMID:12761225)		 RGD PMID:12761225 PMID:17253960 PMID:22952769 PMID:22952873 PMID:21873635 MGI:5462280 MGI:5462286 MGI:7266375, RGD:13792537 NCBI chr 9:76,963,178...76,967,878
Ensembl chr 9:76,963,184...76,967,878 		JBrowse link
G Chpf2 chondroitin polymerizing factor 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:10,578,470...10,585,940
Ensembl chr 4:10,580,462...10,585,916 		JBrowse link
G Chst11 carbohydrate sulfotransferase 11 involved_in
acts_upstream_of_or_within		 ISO (PMID:11056388)
MGI:1926002 (MGI:1354846|PMID:10722746), (MGI:4941099|PMID:21138417)		 RGD PMID:10722746 PMID:11056388 PMID:21138417 MGI:1354846 MGI:4941099 NCBI chr 7:20,524,535...20,743,008
Ensembl chr 7:20,528,100...20,743,111 		JBrowse link
G Chst12 carbohydrate sulfotransferase 12 involved_in ISO (PMID:10781601) RGD PMID:10781601 NCBI chr12:14,110,631...14,129,099
Ensembl chr12:14,110,393...14,129,057 		JBrowse link
G Chst13 carbohydrate sulfotransferase 13 involved_in ISO (PMID:12080076) RGD PMID:12080076 NCBI chr 4:122,824,712...122,837,935
Ensembl chr 4:122,824,022...122,838,019 		JBrowse link
G Chst3 carbohydrate sulfotransferase 3 involved_in
acts_upstream_of_or_within		 IDA
ISO
ISS
IEA
IBA		 (MGI:1206144|PMID:9597547)
GO_REF:0000024
(PMID:15215498), (PMID:9883891)
MGI:2176247 (MGI:1206144|PMID:9597547), (MGI:2156294|PMID:11696535)
GO_REF:0000107
PMID:21873635		 RGD
UniProt
Ensembl		 PMID:9597547 PMID:9883891 PMID:11696535 PMID:15215498 PMID:16495484 More... GO_REF:0000024 GO_REF:0000107 MGI:1206144 MGI:2156294, RGD:1600854, RGD:13792537 NCBI chr20:28,114,387...28,152,046
Ensembl chr20:28,114,404...28,121,807 		JBrowse link
G Chst7 carbohydrate sulfotransferase 7 involved_in IBA
ISO		 PMID:21873635
(PMID:10781596)		 RGD PMID:10781596 PMID:21873635 RGD:13792537 NCBI chr  X:2,396,260...2,432,828
Ensembl chr  X:2,393,874...2,432,840 		JBrowse link
G Chsy1 chondroitin sulfate synthase 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:106576 (MGI:5462286|PMID:22952769)
(PMID:11514575)		 RGD PMID:11514575 PMID:22952769 PMID:21873635 MGI:5462286, RGD:13792537 NCBI chr 1:119,689,626...119,750,711
Ensembl chr 1:119,686,350...119,750,601 		JBrowse link
G Chsy3 chondroitin sulfate synthase 3 involved_in IBA
ISO		 PMID:21873635
MGI:106576 (MGI:7266375|PMID:17253960)		 RGD PMID:17253960 PMID:21873635 MGI:7266375, RGD:13792537 NCBI chr18:52,644,356...52,901,257
Ensembl chr18:52,644,461...52,898,098 		JBrowse link
G Csgalnact1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 involved_in ISO
IBA		 (PMID:11514575), (PMID:12163485)
MGI:1926002|MGI:4868209 (MGI:3708435|PMID:17145758), (MGI:5620532|PMID:25568321), (MGI:6112811|PMID:29287114)
PMID:21873635		 RGD PMID:11514575 PMID:12163485 PMID:17145758 PMID:25568321 PMID:29287114 More... MGI:3708435 MGI:5620532 MGI:6112811, RGD:13792537 NCBI chr16:20,995,210...21,330,586
Ensembl chr16:21,235,784...21,330,319 		JBrowse link
G Csgalnact2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 involved_in IBA
ISO		 PMID:21873635
(MGI:5620532|PMID:25568321)		 RGD PMID:25568321 PMID:21873635 MGI:5620532, RGD:13792537 NCBI chr 4:151,271,774...151,308,856
Ensembl chr 4:151,277,645...151,308,839 		JBrowse link
G Slc35d1 solute carrier family 35 member D1 acts_upstream_of_or_within ISO MGI:3774133 (MGI:3771453|PMID:17952091) RGD PMID:17952091 MGI:3771453 NCBI chr 5:117,928,628...117,981,289
Ensembl chr 5:117,934,352...117,981,311 		JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:2675908|PMID:14505572)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:14505572 GO_REF:0000024 GO_REF:0000107 MGI:2675908 NCBI chr14:42,848,704...42,872,351
Ensembl chr14:42,848,854...42,872,354 		JBrowse link
G Xylt1 xylosyltransferase 1 involved_in IEA
ISO		 GO_REF:0000041
(MGI:5544658|PMID:24161523)		 UniProt
RGD		 PMID:24161523 GO_REF:0000041 MGI:5544658 NCBI chr 1:171,643,925...171,929,774
Ensembl chr 1:171,643,925...171,926,783 		JBrowse link
G Xylt2 xylosyltransferase 2 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr10:79,605,910...79,619,482
Ensembl chr10:79,606,007...79,619,391 		JBrowse link
chondroitin sulfate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hyal4 hyaluronidase 4 acts_upstream_of_or_within ISO (MGI:5490850|PMID:23086929) RGD PMID:23086929 MGI:5490850 NCBI chr 4:53,256,179...53,274,819
Ensembl chr 4:53,256,179...53,274,819 		JBrowse link
chondroitin sulfate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bpnt2 3'(2'), 5'-bisphosphate nucleotidase 2 acts_upstream_of_or_within ISO MGI:3806990|MGI:3810994 (MGI:3799383|PMID:18539921), (MGI:3809386|PMID:18695242) RGD PMID:18539921 PMID:18695242 MGI:3799383 MGI:3809386 NCBI chr 5:17,775,684...17,802,570
Ensembl chr 5:17,772,608...17,802,570 		JBrowse link
G Chst11 carbohydrate sulfotransferase 11 acts_upstream_of_or_within ISO MGI:3768254 (MGI:3767479|PMID:16079159) RGD PMID:16079159 MGI:3767479 NCBI chr 7:20,524,535...20,743,008
Ensembl chr 7:20,528,100...20,743,111 		JBrowse link
G Csgalnact1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 acts_upstream_of_or_within ISO MGI:4868209|MGI:4947395 (MGI:4849906|PMID:20812917), (MGI:4946456|PMID:21148564) RGD PMID:20812917 PMID:21148564 MGI:4849906 MGI:4946456 NCBI chr16:20,995,210...21,330,586
Ensembl chr16:21,235,784...21,330,319 		JBrowse link
G Dse dermatan sulfate epimerase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:26,118,194...26,196,889
Ensembl chr20:26,118,196...26,196,992 		JBrowse link
G Dsel dermatan sulfate epimerase-like involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:5583872 (MGI:5583874|PMID:22496542)		 RGD PMID:22496542 PMID:21873635 MGI:5583874, RGD:13792537 NCBI chr13:186,413...192,592
Ensembl chr13:175,805...192,647 		JBrowse link
G Ext1 exostosin glycosyltransferase 1 acts_upstream_of_or_within ISO (MGI:6478099|PMID:32201365) RGD PMID:32201365 MGI:6478099 NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357 		JBrowse link
dermatan sulfate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chst12 carbohydrate sulfotransferase 12 involved_in ISO (PMID:10781601) RGD PMID:10781601 NCBI chr12:14,110,631...14,129,099
Ensembl chr12:14,110,393...14,129,057 		JBrowse link
G Chst14 carbohydrate sulfotransferase 14 acts_upstream_of_or_within ISO (PMID:11470797) RGD PMID:11470797 NCBI chr 3:105,916,481...105,918,538
Ensembl chr 3:105,916,466...105,918,548 		JBrowse link
G Dse dermatan sulfate epimerase involved_in ISO (PMID:16505484) RGD PMID:16505484 NCBI chr20:26,118,194...26,196,889
Ensembl chr20:26,118,196...26,196,992 		JBrowse link
dermatan sulfate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idua alpha-L-iduronidase involved_in
acts_upstream_of_or_within		 ISO (PMID:24036510)
MGI:2176236|MGI:4415188 (MGI:4397742|PMID:19834056), (MGI:4414887|PMID:19751987)		 RGD PMID:19751987 PMID:19834056 PMID:24036510 MGI:4397742 MGI:4414887 NCBI chr14:1,031,588...1,059,494
Ensembl chr14:1,032,171...1,046,522 		JBrowse link
dermatan sulfate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dse dermatan sulfate epimerase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:26,118,194...26,196,889
Ensembl chr20:26,118,196...26,196,992 		JBrowse link
G Dsel dermatan sulfate epimerase-like involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:5583872 (MGI:5583874|PMID:22496542)		 RGD PMID:22496542 PMID:21873635 MGI:5583874, RGD:13792537 NCBI chr13:186,413...192,592
Ensembl chr13:175,805...192,647 		JBrowse link
heparin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angpt1 angiopoietin 1 involved_in ISO
IEA		 (PMID:19297368)
GO_REF:0000107		 RGD
Ensembl		 PMID:19297368 GO_REF:0000107 NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067 		JBrowse link
G Ext1 exostosin glycosyltransferase 1 acts_upstream_of_or_within_positive_effect ISO (MGI:1888607|PMID:10926768), (MGI:3050709|PMID:15161920), (MGI:3051956|PMID:15177029), (MGI:4360160|PMID:18480751)
MGI:108050 (MGI:6406739|PMID:21310272), (MGI:6406770|PMID:21148566)		 RGD PMID:10926768 PMID:15161920 PMID:15177029 PMID:18480751 PMID:21148566 More... MGI:1888607 MGI:3050709 MGI:3051956 MGI:4360160 MGI:6406739 MGI:6406770 NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357 		JBrowse link
G Ext2 exostosin glycosyltransferase 2 acts_upstream_of_or_within ISO MGI:894663 (MGI:6406739|PMID:21310272) RGD PMID:21310272 MGI:6406739 NCBI chr 3:79,665,415...79,798,077
Ensembl chr 3:79,665,415...79,798,059 		JBrowse link
G Glce glucuronic acid epimerase involved_in IEA
ISO		 GO_REF:0000041
(MGI:2135754|PMID:11279150)		 UniProt
RGD		 PMID:11279150 GO_REF:0000041 MGI:2135754 NCBI chr 8:62,546,104...62,612,144
Ensembl chr 8:62,546,107...62,612,040 		JBrowse link
G Ndst1 N-deacetylase and N-sulfotransferase 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr18:54,136,887...54,199,545
Ensembl chr18:54,140,779...54,178,191 		JBrowse link
G Ndst2 N-deacetylase and N-sulfotransferase 2 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr15:3,563,358...3,573,801
Ensembl chr15:3,563,358...3,573,801 		JBrowse link
G Ndst3 N-deacetylase and N-sulfotransferase 3 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 2:211,702,728...211,868,159
Ensembl chr 2:211,704,898...211,854,584 		JBrowse link
G Ndst4 N-deacetylase and N-sulfotransferase 4 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 2:213,787,010...214,116,569
Ensembl chr 2:213,787,006...214,115,373 		JBrowse link
G Slc10a7 solute carrier family 10, member 7 involved_in ISO (PMID:30082715)
(MGI:6198941|PMID:30082715)		 RGD PMID:30082715 MGI:6198941 NCBI chr19:29,183,143...29,407,470
Ensembl chr19:29,183,155...29,407,464 		JBrowse link
G Xylt2 xylosyltransferase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3714171 (MGI:3713963|PMID:17517600)		 Ensembl
RGD		 PMID:17517600 GO_REF:0000107 MGI:3713963 NCBI chr10:79,605,910...79,619,482
Ensembl chr10:79,606,007...79,619,391 		JBrowse link
heparin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idua alpha-L-iduronidase acts_upstream_of_or_within ISO MGI:2176236|MGI:4415188 (MGI:4397742|PMID:19834056), (MGI:4414887|PMID:19751987), (MGI:5295514|PMID:21873421)
(PMID:21873421)		 RGD PMID:19751987 PMID:19834056 PMID:21873421 MGI:4397742 MGI:4414887 MGI:5295514 NCBI chr14:1,031,588...1,059,494
Ensembl chr14:1,032,171...1,046,522 		JBrowse link
heparin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ednra endothelin receptor type A involved_in ISO MGI:102720|MGI:105923 (MGI:6437578|PMID:27026367) RGD PMID:27026367 MGI:6437578 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049 		JBrowse link
G Ednrb endothelin receptor type B involved_in ISO MGI:102720|MGI:105923 (MGI:6437578|PMID:27026367) RGD PMID:27026367 MGI:6437578 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115 		JBrowse link
G Ext1 exostosin glycosyltransferase 1 acts_upstream_of_or_within ISO (MGI:5704009|PMID:26491162), (MGI:6478099|PMID:32201365) RGD PMID:26491162 PMID:32201365 MGI:5704009 MGI:6478099 NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357 		JBrowse link
G Hpse heparanase involved_in ISO
IEA		 (MGI:6437578|PMID:27026367)
GO_REF:0000107		 RGD
Ensembl		 PMID:27026367 GO_REF:0000107 MGI:6437578 NCBI chr14:8,896,593...8,937,011
Ensembl chr14:8,896,593...8,937,010 		JBrowse link
G Hs2st1 heparan sulfate 2-O-sulfotransferase 1 acts_upstream_of_or_within ISO MGI:1934916 (MGI:2150438|PMID:11457822) RGD PMID:11457822 MGI:2150438 NCBI chr 2:233,508,018...233,641,769
Ensembl chr 2:233,508,021...233,641,769 		JBrowse link
hyaluronan biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc5 ATP binding cassette subfamily C member 5 involved_in ISO (MGI:7262839|PMID:17540771) RGD PMID:17540771 MGI:7262839 NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253 		JBrowse link
G Ccnd3 cyclin D3 IMP RGD PMID:19276076 RGD:2316018 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371 		JBrowse link
G Has1 hyaluronan synthase 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:5508296|PMID:10455188), (MGI:80218|PMID:8626618)
(MGI:1351415|PMID:10617644)		 RGD PMID:8626618 PMID:10455188 PMID:10617644 PMID:21873635 MGI:1351415 MGI:5508296 MGI:80218, RGD:13792537 NCBI chr 1:58,693,411...58,705,653
Ensembl chr 1:58,693,411...58,705,397 		JBrowse link
G Has2 hyaluronan synthase 2 involved_in IEP
ISO
IEA
IBA		 PMID:19635555
(MGI:1861536|PMID:10930438), (MGI:5508296|PMID:10455188), (MGI:82945|PMID:8798545)
(PMID:17324121), (PMID:20507985), (PMID:22016393), (PMID:30394292)
GO_REF:0000041
PMID:21873635
(PMID:17324121), (PMID:22016393)		 RGD
UniProt		 PMID:8798545 PMID:10455188 PMID:10930438 PMID:17324121 PMID:20507985 More... GO_REF:0000041 MGI:1861536 MGI:5508296 MGI:82945, RGD:8553259, RGD:13792537 NCBI chr 7:88,113,326...88,139,337
Ensembl chr 7:88,113,326...88,128,933 		JBrowse link
G Has3 hyaluronan synthase 3 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:5508296|PMID:10455188)
(MGI:86804|PMID:9060470)
(PMID:16900089)		 RGD PMID:9060470 PMID:10455188 PMID:16900089 PMID:21873635 MGI:5508296 MGI:86804, RGD:13792537 NCBI chr19:34,768,421...34,782,170
Ensembl chr19:34,771,982...34,782,592 		JBrowse link
G Hyal1 hyaluronidase 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:21829529)		 UniProt
RGD		 PMID:21829529 GO_REF:0000024 NCBI chr 8:108,250,654...108,254,526
Ensembl chr 8:108,250,667...108,260,210 		JBrowse link
G Il1b interleukin 1 beta involved_in ISO (PMID:15100360) RGD PMID:15100360 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
hyaluronan catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd44 CD44 molecule (Indian blood group) involved_in ISO (PMID:17170110)
(MGI:7264268|PMID:26528478)		 RGD PMID:17170110 PMID:26528478 MGI:7264268 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Cemip cell migration inducing hyaluronidase 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5545862|PMID:24251095)
(PMID:23509262)		 UniProt
RGD		 PMID:23509262 PMID:24251095 GO_REF:0000024 MGI:5545862 NCBI chr 1:137,906,921...138,062,430
Ensembl chr 1:137,908,920...138,062,415 		JBrowse link
G Cemip2 cell migration inducing hyaluronidase 2 involved_in ISO (PMID:28246172) RGD PMID:28246172 NCBI chr 1:219,330,295...219,407,760
Ensembl chr 1:219,337,985...219,407,760 		JBrowse link
G Fgf2 fibroblast growth factor 2 involved_in ISO (PMID:19577615) RGD PMID:19577615 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Gusb glucuronidase, beta involved_in ISO (MGI:4442520|PMID:20385825) RGD PMID:20385825 MGI:4442520 NCBI chr12:26,701,191...26,714,718
Ensembl chr12:26,697,951...26,726,905 		JBrowse link
G Hexa hexosaminidase subunit alpha involved_in ISO MGI:2429698 (MGI:5428797|PMID:22451654) RGD PMID:22451654 MGI:5428797 NCBI chr 8:59,936,526...59,961,654
Ensembl chr 8:59,936,660...59,962,013 		JBrowse link
G Hexb hexosaminidase subunit beta involved_in ISO MGI:2429701 (MGI:5428797|PMID:22451654) RGD PMID:22451654 MGI:5428797 NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223 		JBrowse link
G Hmmr hyaluronan-mediated motility receptor involved_in ISO (MGI:7264268|PMID:26528478) RGD PMID:26528478 MGI:7264268 NCBI chr10:25,132,933...25,163,029
Ensembl chr10:25,132,977...25,163,060 		JBrowse link
G Hyal1 hyaluronidase 1 involved_in IBA
ISO		 PMID:21873635
MGI:2658730 (MGI:5428797|PMID:22451654), (MGI:5828047|PMID:26887442)
(PMID:11296287), (PMID:17170110), (PMID:20473947), (PMID:21695196), (PMID:21699545), (PMID:21829529)
(PMID:12084718)		 RGD PMID:11296287 PMID:12084718 PMID:17170110 PMID:20473947 PMID:21695196 More... MGI:5428797 MGI:5828047, RGD:13792537 NCBI chr 8:108,250,654...108,254,526
Ensembl chr 8:108,250,667...108,260,210 		JBrowse link
G Hyal2 hyaluronidase 2 involved_in IDA
ISO
IEA
IBA		 PMID:19635555
MGI:3836764 (MGI:5469812|PMID:23172227), (MGI:5828047|PMID:26887442)
GO_REF:0000107
PMID:21873635
(PMID:17170110), (PMID:19443707), (PMID:20554532), (PMID:21699545)		 RGD
Ensembl		 PMID:17170110 PMID:19443707 PMID:20554532 PMID:21699545 PMID:23172227 More... GO_REF:0000107 MGI:5469812 MGI:5828047, RGD:8553259, RGD:13792537 NCBI chr 8:108,241,895...108,246,853
Ensembl chr 8:108,243,133...108,246,850 		JBrowse link
G Hyal3 hyaluronidase 3 involved_in ISS
ISO
IBA		 GO_REF:0000024
(MGI:4834982|PMID:20586096)
PMID:21873635
(PMID:21699545)
(PMID:12084718)		 UniProt
RGD		 PMID:12084718 PMID:20586096 PMID:21699545 PMID:21873635 GO_REF:0000024 MGI:4834982, RGD:13792537 NCBI chr 8:108,254,385...108,260,020
Ensembl chr 8:108,250,667...108,260,647 		JBrowse link
G Hyal4 hyaluronidase 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:53,256,179...53,274,819
Ensembl chr 4:53,256,179...53,274,819 		JBrowse link
G Hyal5 hyaluronoglucosaminidase 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:53,341,105...53,412,280
Ensembl chr 4:53,343,475...53,370,785 		JBrowse link
G Hyal6 hyaluronoglucosaminidase 6 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:53,238,118...53,250,783
Ensembl chr 4:53,237,983...53,250,783 		JBrowse link
G Lyve1 lymphatic vessel endothelial hyaluronan receptor 1 involved_in ISO (MGI:2135409|PMID:11278811) RGD PMID:11278811 MGI:2135409 NCBI chr 1:164,962,872...164,976,309
Ensembl chr 1:164,962,872...164,976,309 		JBrowse link
G Spam1 sperm adhesion molecule 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:53,302,745...53,312,913
Ensembl chr 4:53,302,745...53,312,908 		JBrowse link
G Stab2 stabilin 2 involved_in ISO MGI:5318244 (MGI:5315050|PMID:22371575) RGD PMID:22371575 MGI:5315050 NCBI chr 7:21,249,426...21,433,031
Ensembl chr 7:21,249,391...21,434,042 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO
ISS		 (PMID:17324121)
GO_REF:0000024		 RGD
UniProt		 PMID:17324121 GO_REF:0000024 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
hyaluronan metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07028488.1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr17:68,252,128...68,352,207 JBrowse link
G Cemip cell migration inducing hyaluronidase 1 involved_in ISO (MGI:5904067|PMID:28284715), (MGI:6388076|PMID:28189611) RGD PMID:28189611 PMID:28284715 MGI:5904067 MGI:6388076 NCBI chr 1:137,906,921...138,062,430
Ensembl chr 1:137,908,920...138,062,415 		JBrowse link
G Has2 hyaluronan synthase 2 acts_upstream_of_or_within ISO MGI:2176070|MGI:4360705 (MGI:4880794|PMID:21246657) RGD PMID:21246657 MGI:4880794 NCBI chr 7:88,113,326...88,139,337
Ensembl chr 7:88,113,326...88,128,933 		JBrowse link
G Hyal1 hyaluronidase 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:19478093)		 UniProt
RGD		 PMID:19478093 GO_REF:0000024 NCBI chr 8:108,250,654...108,254,526
Ensembl chr 8:108,250,667...108,260,210 		JBrowse link
G Il15 interleukin 15 IDA RGD PMID:17667861 RGD:5013835 NCBI chr19:25,640,013...25,706,818
Ensembl chr19:25,640,251...25,706,820 		JBrowse link
G Itih2 inter-alpha-trypsin inhibitor heavy chain 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr17:68,375,518...68,411,849
Ensembl chr17:68,375,567...68,411,841 		JBrowse link
G Itih3 inter-alpha trypsin inhibitor, heavy chain 3 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr16:6,101,922...6,117,154
Ensembl chr16:6,101,930...6,116,924 		JBrowse link
G Itih4 inter-alpha-trypsin inhibitor heavy chain 4 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr16:6,080,539...6,095,710
Ensembl chr16:6,080,539...6,095,708 		JBrowse link
G Itih5 inter-alpha-trypsin inhibitor heavy chain 5 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr17:68,248,115...68,352,216
Ensembl chr17:68,252,128...68,352,207 		JBrowse link
G Tnfaip6 TNF alpha induced protein 6 involved_in ISO (PMID:20463016), (PMID:26468290) RGD PMID:20463016 PMID:26468290 NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649 		JBrowse link
keratan sulfate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3gnt7 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 involved_in ISO
ISS		 (PMID:17690104)
(MGI:6151274|PMID:29625490)
GO_REF:0000024		 RGD
UniProt		 PMID:17690104 PMID:29625490 GO_REF:0000024 MGI:6151274 NCBI chr 9:86,956,220...86,960,171
Ensembl chr 9:86,956,220...86,960,170 		JBrowse link
G B4galt4 beta-1,4-galactosyltransferase 4 involved_in ISO
ISS		 (PMID:17690104), (PMID:32827291)
GO_REF:0000024		 RGD
UniProt		 PMID:17690104 PMID:32827291 GO_REF:0000024 NCBI chr11:61,995,807...62,021,751
Ensembl chr11:61,995,814...62,021,671 		JBrowse link
G Chst1 carbohydrate sulfotransferase 1 involved_in ISO
ISS		 (PMID:17690104)
GO_REF:0000024		 RGD
UniProt		 PMID:17690104 GO_REF:0000024 NCBI chr 3:78,552,059...78,574,736
Ensembl chr 3:78,548,525...78,574,883 		JBrowse link
G Chst5 carbohydrate sulfotransferase 5 involved_in IBA
ISO		 PMID:21873635
(PMID:11278593), (PMID:17690104)
(MGI:1934540|PMID:11278593)		 RGD PMID:11278593 PMID:17690104 PMID:21873635 MGI:1934540, RGD:13792537 NCBI chr19:39,860,729...39,881,019
Ensembl chr19:39,860,501...39,881,064 		JBrowse link
keratan sulfate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gns glucosamine (N-acetyl)-6-sulfatase IDA RGD PMID:3161730 RGD:1600571 NCBI chr 7:56,889,139...56,923,170
Ensembl chr 7:56,889,232...56,923,151 		JBrowse link
keratan sulfate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chst1 carbohydrate sulfotransferase 1 involved_in ISO
IBA		 (PMID:9405439)
PMID:21873635		 RGD PMID:9405439 PMID:21873635 RGD:13792537 NCBI chr 3:78,552,059...78,574,736
Ensembl chr 3:78,548,525...78,574,883 		JBrowse link
negative regulation of hyaluronan biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap2a1 adaptor related protein complex 2 subunit alpha 1 involved_in ISO (PMID:23509262), (PMID:24251095) RGD PMID:23509262 PMID:24251095 NCBI chr 1:95,384,303...95,414,249
Ensembl chr 1:95,384,309...95,414,147 		JBrowse link
G Cltc clathrin heavy chain involved_in ISO
IEA
ISS		 (PMID:23509262), (PMID:24251095)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:23509262 PMID:24251095 GO_REF:0000024 GO_REF:0000107 NCBI chr10:71,517,661...71,574,591
Ensembl chr10:71,517,663...71,573,737 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1856877 (MGI:5320806|PMID:22383528)		 Ensembl
RGD		 PMID:22383528 GO_REF:0000107 MGI:5320806 NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO
ISS		 (PMID:17324121)
GO_REF:0000024		 RGD
UniProt		 PMID:17324121 GO_REF:0000024 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bgn biglycan acts_upstream_of_or_within ISO (MGI:3807344|PMID:18757743) RGD PMID:18757743 MGI:3807344 NCBI chr  X:151,197,296...151,209,458
Ensembl chr  X:151,197,273...151,209,461 		JBrowse link
G Dcn decorin acts_upstream_of_or_within ISO (MGI:3807344|PMID:18757743) RGD PMID:18757743 MGI:3807344 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270 		JBrowse link
G Egflam EGF-like, fibronectin type III and laminin G domains acts_upstream_of_or_within ISO (MGI:3807344|PMID:18757743) RGD PMID:18757743 MGI:3807344 NCBI chr 2:56,301,945...56,476,665
Ensembl chr 2:56,302,566...56,476,298 		JBrowse link
G Mamdc2 MAM domain containing 2 acts_upstream_of_or_within ISO (MGI:3807344|PMID:18757743) RGD PMID:18757743 MGI:3807344 NCBI chr 1:220,863,959...221,016,493
Ensembl chr 1:220,863,976...221,016,354 		JBrowse link
G Ndnf neuron-derived neurotrophic factor acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:3807344|PMID:18757743)
PMID:21873635		 RGD PMID:18757743 PMID:21873635 MGI:3807344, RGD:13792537 NCBI chr 4:94,944,749...94,987,414
Ensembl chr 4:94,944,360...94,981,873 		JBrowse link
G Prss34 protease, serine, 34 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr10:14,315,913...14,317,712
Ensembl chr10:14,315,955...14,317,712 		JBrowse link
G Spock2 SPARC/osteonectin, cwcv and kazal like domains proteoglycan 2 acts_upstream_of_or_within ISO (MGI:3807344|PMID:18757743) RGD PMID:18757743 MGI:3807344 NCBI chr20:28,036,909...28,064,272
Ensembl chr20:28,033,475...28,064,272 		JBrowse link
G Spock3 SPARC/osteonectin, cwcv and kazal like domains proteoglycan 3 acts_upstream_of_or_within ISO (MGI:3807344|PMID:18757743) RGD PMID:18757743 MGI:3807344 NCBI chr16:26,382,895...26,815,943
Ensembl chr16:26,383,383...26,815,205 		JBrowse link
positive regulation of hyaluronan biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egf epidermal growth factor involved_in ISO
IEA		 (PMID:17324121)
GO_REF:0000107		 RGD
Ensembl		 PMID:17324121 GO_REF:0000107 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
G Has2 hyaluronan synthase 2 IDA
IMP		 RGD PMID:12186949 PMID:17080198 RGD:9588629, RGD:9588632 NCBI chr 7:88,113,326...88,139,337
Ensembl chr 7:88,113,326...88,128,933 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 involved_in ISO (PMID:17324121) RGD PMID:17324121 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in ISO
ISS
IEA		 (PMID:17324121)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:17324121 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
G Ptger4 prostaglandin E receptor 4 IMP RGD PMID:17080198 RGD:9588632 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670 		JBrowse link
regulation of hyaluronan biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smpd3 sphingomyelin phosphodiesterase 3 acts_upstream_of_or_within ISO MGI:1856877 (MGI:5320806|PMID:22383528) RGD PMID:22383528 MGI:5320806 NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18734
    metabolic process 11458
      organic substance metabolic process 11020
        macromolecule metabolic process 9466
          aminoglycan metabolic process 118
            glycosaminoglycan metabolic process 104
              mucopolysaccharide metabolic process 84
                chondroitin sulfate metabolic process + 28
                dermatan sulfate metabolic process + 5
                heparin metabolic process + 15
                hyaluronan metabolic process + 38
                keratan sulfate metabolic process + 5
paths to the root