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ONTOLOGY REPORT - ANNOTATIONS

Term:reactive oxygen species biosynthetic process
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Accession:GO:1903409 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen.
Synonyms:exact_synonym: reactive oxygen species anabolism;   reactive oxygen species biosynthesis;   reactive oxygen species formation;   reactive oxygen species synthesis
 related_synonym: ROS formation;   ROS generation;   reactive oxygen species generation


show annotations for term's descendants           Sort by:
reactive oxygen species biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHR aryl hydrocarbon receptor ISO RGD PMID:35788946 RGD:401793705 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152 		JBrowse link
G GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1 involved_in IMP (PMID:22573891) UniProt PMID:22573891 NCBI chr10:102,230,643...102,382,896
Ensembl chr10:102,245,371...102,382,899 		JBrowse link
G INAVA innate immunity activator involved_in IMP (PMID:28436939) UniProt PMID:28436939 NCBI chr 1:200,891,531...200,915,742
Ensembl chr 1:200,891,048...200,915,742 		JBrowse link
G LIPA lipase A, lysosomal acid type acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5560864|PMID:24287405) MGI
Ensembl		 PMID:24287405 GO_REF:0000107 MGI:5560864 NCBI chr10:89,213,572...89,251,775
Ensembl chr10:89,213,569...89,414,557 		JBrowse link
G NCF1 neutrophil cytosolic factor 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:21275845 GO_REF:0000107 RGD:41404729 NCBI chr 7:74,774,011...74,789,315
Ensembl chr 7:74,774,011...74,789,315 		JBrowse link
G NOX4 NADPH oxidase 4 involved_in NAS (PMID:27525436) ARUK-UCL PMID:27525436 NCBI chr11:89,324,353...89,589,557
Ensembl chr11:89,324,353...89,498,187 		JBrowse link
hydrogen peroxide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACOX1 acyl-CoA oxidase 1 involved_in IMP (PMID:32169171) FlyBase PMID:32169171 NCBI chr17:75,941,507...75,979,166
Ensembl chr17:75,941,507...75,979,177 		JBrowse link
G CYBA cytochrome b-245 alpha chain involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr16:88,643,289...88,651,053
Ensembl chr16:88,643,275...88,651,083 		JBrowse link
G CYBB cytochrome b-245 beta chain acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3050718|PMID:15258578) MGI
Ensembl		 PMID:15258578 GO_REF:0000107 MGI:3050718 NCBI chr  X:37,780,059...37,813,461
Ensembl chr  X:37,780,018...37,813,461 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3037497|PMID:14980704) MGI
Ensembl		 PMID:14980704 GO_REF:0000107 MGI:3037497 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3037497|PMID:14980704) MGI
Ensembl		 PMID:14980704 GO_REF:0000107 MGI:3037497 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607 		JBrowse link
G DUOX1 dual oxidase 1 involved_in IGI
NAS		 (PMID:19339556), (PMID:22814254)
(PMID:10806195)		 UniProt PMID:10806195 PMID:19339556 PMID:22814254 NCBI chr15:45,129,994...45,165,574
Ensembl chr15:45,129,933...45,165,576 		JBrowse link
G DUOX2 dual oxidase 2 involved_in IGI (PMID:16651268), (PMID:19339556), (PMID:22814254), (PMID:25761904) UniProt PMID:16651268 PMID:19339556 PMID:22814254 PMID:25761904 NCBI chr15:45,092,650...45,114,172
Ensembl chr15:45,092,650...45,114,172 		JBrowse link
G MAOB monoamine oxidase B involved_in NAS (PMID:24252804) ParkinsonsUK-UCL PMID:24252804 NCBI chr  X:43,766,610...43,882,450
Ensembl chr  X:43,766,610...43,882,450 		JBrowse link
G NCF1 neutrophil cytosolic factor 1 acts_upstream_of_or_within ISO (MGI:3050718|PMID:15258578) MGI PMID:15258578 MGI:3050718 NCBI chr 7:74,774,011...74,789,315
Ensembl chr 7:74,774,011...74,789,315 		JBrowse link
G SOD1 superoxide dismutase 1 involved_in
acts_upstream_of_or_within		 ISO
IEA
IDA
ISS		 (PMID:15544046)
(MGI:2682495|PMID:14679182)		 RGD
Ensembl
UniProt
MGI		 PMID:10640619 PMID:12514262 PMID:14679182 PMID:15544046 PMID:15880490 GO_REF:0000024 GO_REF:0000107 MGI:2682495 RGD:1581090 RGD:1601266 RGD:634854 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931 		JBrowse link
G SOD2 superoxide dismutase 2 involved_in ISO
IEA		 RGD
Ensembl		 PMID:15642720 GO_REF:0000107 RGD:2291946 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
hypochlorous acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MPO myeloperoxidase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1333719|PMID:10085024) MGI
Ensembl		 PMID:10085024 GO_REF:0000107 MGI:1333719 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935 		JBrowse link
negative regulation of hydrogen peroxide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CTNS cystinosin, lysosomal cystine transporter involved_in ISO
IEA		 RGD
Ensembl		 PMID:26482480 GO_REF:0000107 RGD:12910938 NCBI chr17:3,636,459...3,663,103
Ensembl chr17:3,636,459...3,663,103 		JBrowse link
G CYCS cytochrome c, somatic ISO RGD PMID:21410437 RGD:7349317 NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260 		JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase involved_in ISS (PMID:27525436) ARUK-UCL PMID:27525436 NCBI chr 6:111,660,332...111,873,452
Ensembl chr 6:111,660,332...111,873,452 		JBrowse link
G MPV17L MPV17 mitochondrial inner membrane protein like involved_in IDA (PMID:22306510) BHF-UCL PMID:22306510 NCBI chr16:15,395,754...15,413,271
Ensembl chr16:15,395,754...15,413,271 		JBrowse link
G PRL prolactin involved_in ISO (PMID:24530842) AgBase PMID:24530842 NCBI chr 6:22,287,246...22,302,835
Ensembl chr 6:22,287,244...22,302,826 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO RGD PMID:23590160 RGD:8694322 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,540 		JBrowse link
negative regulation of reactive oxygen species biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB7 ATP binding cassette subfamily B member 7 involved_in ISS UniProt GO_REF:0000024 NCBI chr  X:75,051,048...75,156,283
Ensembl chr  X:75,051,048...75,156,732 		JBrowse link
G ABCD1 ATP binding cassette subfamily D member 1 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:153,724,856...153,744,755
Ensembl chr  X:153,724,856...153,744,755 		JBrowse link
G ABCD2 ATP binding cassette subfamily D member 2 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:39,531,025...39,619,803
Ensembl chr12:39,550,033...39,619,803 		JBrowse link
G ADCY10 adenylate cyclase 10 involved_in ISO
IEA		 RGD
Ensembl		 PMID:32664470 GO_REF:0000107 RGD:329347825 NCBI chr 1:167,809,386...167,914,134
Ensembl chr 1:167,809,386...167,914,215 		JBrowse link
G ATP5MC1 ATP synthase membrane subunit c locus 1 ISO RGD PMID:22209705 RGD:13800744 NCBI chr17:48,892,787...48,895,871
Ensembl chr17:48,892,765...48,895,871 		JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator involved_in ISO
IEA		 RGD
Ensembl		 PMID:18292530 GO_REF:0000107 RGD:11341712 NCBI chr 2:201,116,164...201,176,687
Ensembl chr 2:201,116,154...201,176,687 		JBrowse link
G COA8 cytochrome c oxidase assembly factor 8 involved_in IMP (PMID:25175347) UniProt PMID:25175347 NCBI chr14:103,562,960...103,590,899
Ensembl chr14:103,562,960...103,607,523 		JBrowse link
G CTNS cystinosin, lysosomal cystine transporter involved_in ISO
IEA		 RGD
Ensembl		 PMID:26482480 GO_REF:0000107 RGD:12910938 NCBI chr17:3,636,459...3,663,103
Ensembl chr17:3,636,459...3,663,103 		JBrowse link
G EEF1A1 eukaryotic translation elongation factor 1 alpha 1 ISO RGD PMID:23041468 RGD:10401126 NCBI chr 6:73,515,750...73,521,032
Ensembl chr 6:73,489,308...73,525,587 		JBrowse link
G HBP1 HMG-box transcription factor 1 involved_in ISO (MGI:5754467|PMID:24675724) BHF-UCL PMID:24675724 MGI:5754467 NCBI chr 7:107,169,003...107,202,522
Ensembl chr 7:107,168,961...107,202,522 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha ISO RGD PMID:26071548 RGD:401793712 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 ISO RGD PMID:22547655 RGD:10402548 NCBI chr 2:197,486,584...197,500,274
Ensembl chr 2:197,486,584...197,516,737 		JBrowse link
G INS insulin involved_in IGI (PMID:19188609) ARUK-UCL PMID:19188609 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221 		JBrowse link
G MFN2 mitofusin 2 ISO RGD PMID:28483668 RGD:12910717 NCBI chr 1:11,980,444...12,013,508
Ensembl chr 1:11,980,181...12,015,211 		JBrowse link
G MIR140 microRNA 140 ISO RGD PMID:32519270 RGD:329347827 NCBI chr16:69,933,081...69,933,180
Ensembl chr16:69,933,081...69,933,180 		JBrowse link
G MIR181A1 microRNA 181a-1 involved_in IDA (PMID:23516523) ARUK-UCL PMID:23516523 NCBI chr 1:198,859,044...198,859,153
Ensembl chr 1:198,859,044...198,859,153 		JBrowse link
G MIR181A2 microRNA 181a-2 involved_in IDA (PMID:23516523) ARUK-UCL PMID:23516523 NCBI chr 9:124,692,442...124,692,551
Ensembl chr 9:124,692,442...124,692,551 		JBrowse link
G MIR21 microRNA 21 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337 		JBrowse link
G MIR590 microRNA 590 involved_in IDA (PMID:26648441) BHF-UCL PMID:26648441 NCBI chr 7:74,191,198...74,191,294
Ensembl chr 7:74,191,198...74,191,294 		JBrowse link
G NDUFC2 NADH:ubiquinone oxidoreductase subunit C2 ISO RGD PMID:26888427 RGD:11040458 NCBI chr11:78,068,297...78,079,862
Ensembl chr11:78,068,297...78,079,862 		JBrowse link
G PAGE4 PAGE family member 4 involved_in IDA (PMID:25374899) UniProt PMID:25374899 NCBI chr  X:49,829,260...49,834,264
Ensembl chr  X:49,829,260...49,834,264 		JBrowse link
G PARK7 Parkinsonism associated deglycase involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:7,961,711...7,985,505
Ensembl chr 1:7,954,291...7,985,505 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha acts_upstream_of IMP (PMID:31574452) ARUK-UCL PMID:31574452 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase ISO RGD PMID:24096089 RGD:10413842 NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775 		JBrowse link
G RHOA ras homolog family member A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:49,359,145...49,411,976
Ensembl chr 3:49,359,139...49,412,998 		JBrowse link
G SIRT1 sirtuin 1 ISO RGD PMID:23422569 RGD:9585767 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390 		JBrowse link
G SLC18A2 solute carrier family 18 member A2 involved_in NAS (PMID:24252804) ParkinsonsUK-UCL PMID:24252804 NCBI chr10:117,241,114...117,279,430
Ensembl chr10:117,241,093...117,279,430 		JBrowse link
G TRAP1 TNF receptor associated protein 1 involved_in TAS (PMID:18221368) ParkinsonsUK-UCL PMID:18221368 NCBI chr16:3,658,037...3,717,524
Ensembl chr16:3,651,639...3,717,553 		JBrowse link
positive regulation of hydrogen peroxide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DUOXA1 dual oxidase maturation factor 1 involved_in IMP (PMID:22814254) UniProt PMID:22814254 NCBI chr15:45,117,366...45,129,879
Ensembl chr15:45,117,366...45,129,938 		JBrowse link
G DUOXA2 dual oxidase maturation factor 2 involved_in IDA
IMP		 (PMID:16651268)
(PMID:22814254)		 UniProt PMID:16651268 PMID:22814254 NCBI chr15:45,114,326...45,118,421
Ensembl chr15:45,114,326...45,118,421 		JBrowse link
G MFN2 mitofusin 2 ISO RGD PMID:27997345 RGD:12910740 NCBI chr 1:11,980,444...12,013,508
Ensembl chr 1:11,980,181...12,015,211 		JBrowse link
G NOX4 NADPH oxidase 4 ISO RGD PMID:27279484 RGD:151347625 NCBI chr11:89,324,353...89,589,557
Ensembl chr11:89,324,353...89,498,187 		JBrowse link
G SOD2 superoxide dismutase 2 involved_in ISO
IEA		 RGD
Ensembl		 PMID:20529999 GO_REF:0000107 RGD:27095884 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G ZNF205 zinc finger protein 205 involved_in IMP (PMID:22306510) BHF-UCL PMID:22306510 NCBI chr16:3,112,586...3,120,517
Ensembl chr16:3,112,560...3,120,517 		JBrowse link
positive regulation of reactive oxygen species biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY10 adenylate cyclase 10 involved_in ISO
IEA		 RGD
Ensembl		 PMID:28386847 GO_REF:0000107 RGD:329337357 NCBI chr 1:167,809,386...167,914,134
Ensembl chr 1:167,809,386...167,914,215 		JBrowse link
G ADGRB1 adhesion G protein-coupled receptor B1 involved_in IMP (PMID:26838550) UniProt PMID:26838550 NCBI chr 8:142,449,649...142,545,007
Ensembl chr 8:142,449,430...142,545,009 		JBrowse link
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO RGD PMID:15450084 RGD:2313867 NCBI chr17:6,996,049...7,010,754
Ensembl chr17:6,996,049...7,010,754 		JBrowse link
G CD36 CD36 molecule involved_in IEA
ISS		 Ensembl
ARUK-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277 		JBrowse link
G CLCN3 chloride voltage-gated channel 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3663198|PMID:16522634) MGI
Ensembl		 PMID:16522634 GO_REF:0000107 MGI:3663198 NCBI chr 4:169,620,578...169,723,673
Ensembl chr 4:169,612,633...169,723,673 		JBrowse link
G CYBA cytochrome b-245 alpha chain involved_in IDA (PMID:22423966) UniProt PMID:22423966 NCBI chr16:88,643,289...88,651,053
Ensembl chr16:88,643,275...88,651,083 		JBrowse link
G FOXO3 forkhead box O3 involved_in ISO
IEA		 RGD
Ensembl		 PMID:24278276 GO_REF:0000107 RGD:10402204 NCBI chr 6:108,559,825...108,684,774
Ensembl chr 6:108,559,835...108,684,774 		JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr 9:137,139,154...137,168,756
Ensembl chr 9:137,138,346...137,168,756 		JBrowse link
G H19 H19 imprinted maternally expressed transcript acts_upstream_of IMP (PMID:31574452) ARUK-UCL PMID:31574452 NCBI chr11:1,995,176...2,001,466
Ensembl chr11:1,995,166...2,004,552 		JBrowse link
G HDAC4 histone deacetylase 4 ISO RGD PMID:24166750 RGD:9681442 NCBI chr 2:239,048,168...239,401,649
Ensembl chr 2:239,048,168...239,401,654 		JBrowse link
G IL4 interleukin 4 ISO RGD PMID:24073824 RGD:10402792 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G LCN2 lipocalin 2 ISO RGD PMID:25557118 RGD:126790477 NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453 		JBrowse link
G MFN2 mitofusin 2 ISO RGD PMID:27997345 RGD:12910740 NCBI chr 1:11,980,444...12,013,508
Ensembl chr 1:11,980,181...12,015,211 		JBrowse link
G MIR24-1 microRNA 24-1 involved_in IDA (PMID:21788589) BHF-UCL PMID:21788589 NCBI chr 9:95,086,021...95,086,088
Ensembl chr 9:95,086,021...95,086,088 		JBrowse link
G MIR24-2 microRNA 24-2 involved_in IDA (PMID:21788589) BHF-UCL PMID:21788589 NCBI chr19:13,836,287...13,836,359
Ensembl chr19:13,836,287...13,836,359 		JBrowse link
G MIR675 microRNA 675 acts_upstream_of IDA (PMID:31574452) ARUK-UCL PMID:31574452 NCBI chr11:1,996,759...1,996,831
Ensembl chr11:1,996,759...1,996,831 		JBrowse link
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase ISO RGD PMID:21712532 RGD:9590189 NCBI chr  X:71,533,104...71,575,892
Ensembl chr  X:71,533,087...71,575,892 		JBrowse link
G PARK7 Parkinsonism associated deglycase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5543357|PMID:22555455) MGI
Ensembl		 PMID:22555455 GO_REF:0000107 MGI:5543357 NCBI chr 1:7,961,711...7,985,505
Ensembl chr 1:7,954,291...7,985,505 		JBrowse link
G PLCG2 phospholipase C gamma 2 acts_upstream_of
involved_in		 ISS
IEA		 ARUK-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr16:81,779,291...81,962,685
Ensembl chr16:81,779,279...81,962,685 		JBrowse link
G RAB27A RAB27A, member RAS oncogene family involved_in IMP (PMID:24404184) UniProt PMID:24404184 NCBI chr15:55,202,966...55,289,813
Ensembl chr15:55,202,966...55,319,113 		JBrowse link
G SLC5A3 solute carrier family 5 member 3 involved_in
acts_upstream_of_or_within		 IEA
ISS		 Ensembl
ARUK-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr21:34,073,578...34,106,260
Ensembl chr21:34,073,578...34,106,260 		JBrowse link
G TLR4 toll like receptor 4 involved_in ISS
IEA		 ARUK-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TLR6 toll like receptor 6 involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr 4:38,822,897...38,868,390
Ensembl chr 4:38,822,897...38,856,817 		JBrowse link
regulation of reactive oxygen species biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX5 arachidonate 5-lipoxygenase involved_in IMP (PMID:26210919) UniProt PMID:26210919 NCBI chr10:45,374,216...45,446,117
Ensembl chr10:45,374,176...45,446,119 		JBrowse link
G ARG2 arginase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:67,619,920...67,651,708
Ensembl chr14:67,619,920...67,651,708 		JBrowse link
G CCN6 cellular communication network factor 6 involved_in IMP (PMID:27252383) UniProt PMID:27252383 NCBI chr 6:112,052,813...112,069,686
Ensembl chr 6:112,054,075...112,069,686 		JBrowse link
G NCF2 neutrophil cytosolic factor 2 ISO RGD PMID:27279484 RGD:151347625 NCBI chr 1:183,555,562...183,601,849
Ensembl chr 1:183,554,461...183,590,905 		JBrowse link
G PIKFYVE phosphoinositide kinase, FYVE-type zinc finger containing involved_in IDA
IBA
IEA		 (PMID:28779020)
(PMID:21873635)		 UniProt
GO_Central
Ensembl		 PMID:21873635 PMID:28779020 GO_REF:0000107 NCBI chr 2:208,266,056...208,358,746
Ensembl chr 2:208,266,255...208,358,746 		JBrowse link
G SLC25A33 solute carrier family 25 member 33 involved_in IMP (PMID:20453889) UniProt PMID:20453889 NCBI chr 1:9,539,465...9,585,173
Ensembl chr 1:9,539,465...9,585,173 		JBrowse link
G SNCA synuclein alpha involved_in TAS (PMID:24252804) ParkinsonsUK-UCL PMID:24252804 NCBI chr 4:89,724,099...89,838,304
Ensembl chr 4:89,700,345...89,838,315 		JBrowse link
G SPHK2 sphingosine kinase 2 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr19:48,619,506...48,630,405
Ensembl chr19:48,619,291...48,630,717 		JBrowse link
G UCP1 uncoupling protein 1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000104 GO_REF:0000107 NCBI chr 4:140,559,431...140,568,961
Ensembl chr 4:140,559,431...140,568,961 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19565
    metabolic process 12598
      biosynthetic process 9153
        reactive oxygen species biosynthetic process 81
          hydrogen peroxide biosynthetic process + 22
          hypochlorous acid biosynthetic process 1
          negative regulation of reactive oxygen species biosynthetic process + 33
          positive regulation of reactive oxygen species biosynthetic process + 28
          regulation of reactive oxygen species biosynthetic process + 67
Path 2
Term Annotations click to browse term
  biological_process 19565
    metabolic process 12598
      cellular metabolic process 11273
        reactive oxygen species metabolic process 285
          reactive oxygen species biosynthetic process 81
            hydrogen peroxide biosynthetic process + 22
            hypochlorous acid biosynthetic process 1
            negative regulation of reactive oxygen species biosynthetic process + 33
            positive regulation of reactive oxygen species biosynthetic process + 28
            regulation of reactive oxygen species biosynthetic process + 67
paths to the root