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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
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Accession:GO:1903377 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway.
Synonyms:exact_synonym: down regulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress;   downregulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress;   negative regulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress;   negative regulation of oxidative stress-induced neuron apoptosis
 narrow_synonym: inhibition of neuron intrinsic apoptotic signaling pathway in response to oxidative stress
 related_synonym: down regulation of neuron apoptosis in response to oxidative stress;   downregulation of neuron apoptosis in response to oxidative stress;   inhibition of neuron apoptosis in response to oxidative stress;   negative regulation of neuron apoptosis in response to oxidative stress;   neuroprotection against oxidative stress-induced apoptosis;   protection against oxidative stress-induced neuron apoptosis;   protection against oxidative stress-induced neuronal apoptosis



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negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf4 activating transcription factor 4 involved_in IMP
ISO
PMID:23392669
UniProtKB:Q9ES19 (PMID:23392669)
RGD PMID:23392669 PMID:23392669 RGD:10047168 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Ctnnb1 catenin beta 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:5770063|PMID:21752258)
Ensembl
RGD
PMID:21752258 GO_REF:0000107 MGI:5770063 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Fbxo7 F-box protein 7 acts_upstream_of
involved_in
ISO (PMID:26310625)
(PMID:25029497)
RGD PMID:25029497 PMID:26310625 NCBI chr 7:17,809,224...17,837,549
Ensembl chr 7:17,809,231...17,837,530
JBrowse link
G Fzd1 frizzled class receptor 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:5770063|PMID:21752258)
Ensembl
RGD
PMID:21752258 GO_REF:0000107 MGI:5770063 NCBI chr 4:29,310,303...29,314,701
Ensembl chr 4:29,310,091...29,312,643
Ensembl chr 4:29,310,091...29,312,643
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha involved_in ISO
IEA
(PMID:24899725)
GO_REF:0000107
RGD
Ensembl
PMID:24899725 GO_REF:0000107 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Il10 interleukin 10 involved_in ISO ComplexPortal:CPX-1134 (MGI:5291547|PMID:21857966) RGD PMID:21857966 MGI:5291547 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Nono non-POU domain containing, octamer-binding involved_in ISO (PMID:15790595) RGD PMID:15790595 NCBI chr  X:66,554,131...66,571,992
Ensembl chr  X:66,554,098...66,571,952
JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISS
ISO
GO_REF:0000024
(MGI:5575789|PMID:24899725)
(PMID:15790595), (PMID:16632486), (PMID:23743200)
ParkinsonsUK-UCL
RGD
PMID:15790595 PMID:16632486 PMID:23743200 PMID:24899725 GO_REF:0000024 MGI:5575789 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:16632486) RGD PMID:16632486 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
ISS
IEA
IGI
(PMID:17314283)
GO_REF:0000024
(MGI:5543313|PMID:23858059)
GO_REF:0000107
PMID:23392669
RGD
ParkinsonsUK-UCL
Ensembl
PMID:17314283 PMID:23858059 PMID:23392669 GO_REF:0000024 GO_REF:0000107 MGI:5543313, RGD:10047168 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
JBrowse link
G Pycr1 pyrroline-5-carboxylate reductase 1 involved_in ISO (PMID:23743200) RGD PMID:23743200 NCBI chr10:105,917,732...105,922,658
Ensembl chr10:105,917,680...105,922,549
JBrowse link
G Wnt1 Wnt family member 1 involved_in ISO (MGI:5770063|PMID:21752258) RGD PMID:21752258 MGI:5770063 NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651
JBrowse link
negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase involved_in ISO
IEA
UniProtKB:Q99LX0 (PMID:14652021)
(MGI:5613479|PMID:14652021)
GO_REF:0000107
RGD
Ensembl
PMID:14652021 GO_REF:0000107 MGI:5613479 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:21177249), (PMID:23261939) RGD PMID:21177249 PMID:23261939 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20325
    cellular process 18797
      negative regulation of cellular process 5409
        negative regulation of programmed cell death 1100
          negative regulation of apoptotic process 1062
            negative regulation of neuron apoptotic process 220
              negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway 12
                negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway 2
Path 2
Term Annotations click to browse term
  biological_process 20325
    biological regulation 13633
      regulation of biological process 13227
        regulation of cellular process 12688
          signal transduction 7177
            apoptotic signaling pathway 692
              regulation of apoptotic signaling pathway 464
                negative regulation of apoptotic signaling pathway 266
                  negative regulation of intrinsic apoptotic signaling pathway 119
                    negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 30
                      negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway 12
                        negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway 2
paths to the root