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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
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Accession:GO:1903376 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway.
Synonyms:exact_synonym: regulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress
 broad_synonym: regulation of oxidative stress-induced neuron apoptosis;   regulation of oxidative stress-induced neuronal apoptosis
 related_synonym: regulation of neuron apoptosis in response to oxidative stress



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regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase involved_in ISO (PMID:15983381) RGD PMID:15983381 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 IMP RGD PMID:17347665 RGD:10414071 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Prodh proline dehydrogenase involved_in ISO (PMID:23743200) RGD PMID:23743200 NCBI chr11:82,910,043...82,927,305
Ensembl chr11:82,910,137...82,927,305
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6458378|PMID:30684126) RGD PMID:30684126 MGI:6458378 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170
JBrowse link
negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase involved_in ISO
IEA
UniProtKB:Q99LX0 (PMID:14652021)
(MGI:5613479|PMID:14652021)
GO_REF:0000107
RGD
Ensembl
PMID:14652021 GO_REF:0000107 MGI:5613479 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:21177249), (PMID:23261939) RGD PMID:21177249 PMID:23261939 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf4 activating transcription factor 4 involved_in IMP
ISO
PMID:23392669
UniProtKB:Q9ES19 (PMID:23392669)
RGD PMID:23392669 PMID:23392669 RGD:10047168 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Ctnnb1 catenin beta 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:5770063|PMID:21752258)
Ensembl
RGD
PMID:21752258 GO_REF:0000107 MGI:5770063 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Fbxo7 F-box protein 7 acts_upstream_of
involved_in
ISO (PMID:26310625)
(PMID:25029497)
RGD PMID:25029497 PMID:26310625 NCBI chr 7:17,809,224...17,837,549
Ensembl chr 7:17,809,231...17,837,530
JBrowse link
G Fzd1 frizzled class receptor 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:5770063|PMID:21752258)
Ensembl
RGD
PMID:21752258 GO_REF:0000107 MGI:5770063 NCBI chr 4:29,310,303...29,314,701
Ensembl chr 4:29,310,091...29,312,643
Ensembl chr 4:29,310,091...29,312,643
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha involved_in ISO
IEA
(PMID:24899725)
GO_REF:0000107
RGD
Ensembl
PMID:24899725 GO_REF:0000107 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Il10 interleukin 10 involved_in ISO ComplexPortal:CPX-1134 (MGI:5291547|PMID:21857966) RGD PMID:21857966 MGI:5291547 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Nono non-POU domain containing, octamer-binding involved_in ISO (PMID:15790595) RGD PMID:15790595 NCBI chr  X:66,554,131...66,571,992
Ensembl chr  X:66,554,098...66,571,952
JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISS
ISO
GO_REF:0000024
(MGI:5575789|PMID:24899725)
(PMID:15790595), (PMID:16632486), (PMID:23743200)
ParkinsonsUK-UCL
RGD
PMID:15790595 PMID:16632486 PMID:23743200 PMID:24899725 GO_REF:0000024 MGI:5575789 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:16632486) RGD PMID:16632486 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
ISS
IEA
IGI
(PMID:17314283)
GO_REF:0000024
(MGI:5543313|PMID:23858059)
GO_REF:0000107
PMID:23392669
RGD
ParkinsonsUK-UCL
Ensembl
PMID:17314283 PMID:23858059 PMID:23392669 GO_REF:0000024 GO_REF:0000107 MGI:5543313, RGD:10047168 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
JBrowse link
G Pycr1 pyrroline-5-carboxylate reductase 1 involved_in ISO (PMID:23743200) RGD PMID:23743200 NCBI chr10:105,917,732...105,922,658
Ensembl chr10:105,917,680...105,922,549
JBrowse link
G Wnt1 Wnt family member 1 involved_in ISO (MGI:5770063|PMID:21752258) RGD PMID:21752258 MGI:5770063 NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651
JBrowse link
positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy10 adenylate cyclase 10 IMP RGD PMID:28386847 RGD:329337357 NCBI chr13:77,747,752...77,833,952
Ensembl chr13:77,768,468...77,833,951
JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 involved_in ISO (PMID:23858059)
(MGI:5543313|PMID:23858059)
RGD PMID:23858059 MGI:5543313 NCBI chr 2:170,149,706...170,311,536
Ensembl chr 2:170,149,694...170,309,941
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member involved_in ISO UniProtKB:Q9WVS6 (PMID:23858059)
(MGI:5543313|PMID:23858059)
RGD PMID:23858059 MGI:5543313 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Mmp2 matrix metallopeptidase 2 IMP RGD PMID:27614125 RGD:329961568 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Ralbp1 ralA binding protein 1 IMP RGD PMID:23788031 RGD:12904719 NCBI chr 9:105,456,425...105,493,235
Ensembl chr 9:105,456,425...105,492,707
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20325
    cellular process 18797
      regulation of cellular process 12688
        regulation of programmed cell death 1780
          regulation of apoptotic process 1724
            regulation of neuron apoptotic process 336
              regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway 20
                negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway + 12
                positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway 5
                regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway + 2
Path 2
Term Annotations click to browse term
  biological_process 20325
    biological regulation 13633
      regulation of biological process 13227
        signaling 7729
          signal transduction 7177
            intracellular signal transduction 2825
              intrinsic apoptotic signaling pathway 342
                intrinsic apoptotic signaling pathway in response to oxidative stress 65
                  neuron intrinsic apoptotic signaling pathway in response to oxidative stress 22
                    regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway 20
                      negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway + 12
                      positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway 5
                      regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway + 2
paths to the root