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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of protein maturation
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Accession:GO:1903318 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of protein maturation.
Synonyms:exact_synonym: down regulation of protein maturation;   downregulation of protein maturation
 narrow_synonym: inhibition of protein maturation


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inhibition of cysteine-type endopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cast calpastatin involved_in ISO
IBA
(PMID:2407243)
PMID:21873635
RGD PMID:2407243, PMID:21873635 RGD:13792537 NCBI chr 2:3,973,112...4,082,658 JBrowse link
G Cst7 cystatin F involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:5910746 (MGI:5904382|PMID:28251676)
RGD PMID:28251676, PMID:21873635 MGI:5904382, RGD:13792537 NCBI chr 3:139,396,830...139,405,557 JBrowse link
G Nlrp1b NLR family, pyrin domain containing 1B involved_in ISO (PMID:11821383) RGD PMID:11821383 NCBI chr10:55,838,381...55,904,374 JBrowse link
G Nol3 nucleolar protein 3 involved_in IDA
IMP
PMID:17292893
PMID:16639714
UniProt PMID:17292893, PMID:16639714 RGD:10047212, RGD:10047164 NCBI chr19:33,154,061...33,158,250 JBrowse link
inhibition of cysteine-type endopeptidase activity involved in apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2l12 BCL2 like 12 involved_in ISO (PMID:22262180) RGD PMID:22262180 NCBI chr 1:95,472,272...95,480,991 JBrowse link
G Fcmr Fc fragment of IgM receptor acts_upstream_of_or_within ISO (MGI:3576402|PMID:15632112) RGD PMID:15632112 MGI:3576402 NCBI chr13:42,337,363...42,351,706 JBrowse link
G Nol3 nucleolar protein 3 involved_in ISO
IEA
(PMID:15509781)
GO_REF:0000107
RGD
Ensembl
PMID:15509781 GO_REF:0000107 NCBI chr19:33,154,061...33,158,250 JBrowse link
G Xiap X-linked inhibitor of apoptosis involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:2681362|PMID:14623868)
Ensembl
RGD
PMID:14623868 GO_REF:0000107 MGI:2681362 NCBI chr  X:120,890,537...120,938,413 JBrowse link
negative regulation of plasminogen activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cpb2 carboxypeptidase B2 IMP RGD PMID:23369837 RGD:7243115 NCBI chr15:50,557,722...50,606,569 JBrowse link
G Ctsz cathepsin Z involved_in ISO (PMID:19433310) RGD PMID:19433310 NCBI chr 3:163,224,875...163,235,645 JBrowse link
G Serpine1 serpin family E member 1 involved_in IEA
IBA
ISO
GO_REF:0000107
PMID:21873635
(MGI:4418017|PMID:19855083)
(PMID:18835034), (PMID:19855083), (PMID:8508955)
Ensembl
RGD
PMID:8508955 PMID:18835034 PMID:19855083, PMID:21873635 GO_REF:0000107 MGI:4418017, RGD:13792537 NCBI chr12:19,601,272...19,611,657 JBrowse link
G Serpine2 serpin family E member 2 involved_in ISO
IBA
IEA
(PMID:19855083)
PMID:21873635
GO_REF:0000107
(MGI:4418017|PMID:19855083)
RGD
Ensembl
PMID:19855083, PMID:21873635 GO_REF:0000107 MGI:4418017, RGD:13792537 NCBI chr 9:81,124,746...81,188,866 JBrowse link
G Serpinf2 serpin family F member 2 involved_in ISO (PMID:134998) RGD PMID:134998 NCBI chr10:60,272,400...60,280,506 JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO (PMID:6438154) RGD PMID:6438154 NCBI chr 3:105,056,286...105,071,445 JBrowse link
negative regulation of protein processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp4 acid phosphatase 4 involved_in ISO (PMID:15219672) RGD PMID:15219672 NCBI chr 1:94,736,376...94,751,871 JBrowse link
G Cdh1 cadherin 1 acts_upstream_of_or_within ISO (MGI:3763814|PMID:17344476) RGD PMID:17344476 MGI:3763814 NCBI chr19:34,492,371...34,561,775 JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 involved_in ISO
ISS
(PMID:22445366)
GO_REF:0000024
RGD
UniProt
PMID:22445366 GO_REF:0000024 NCBI chr 3:106,342,302...106,345,526 JBrowse link
G Fmr1 FMRP translational regulator 1 IMP Casp3 RGD PMID:22817682 RGD:11566024 NCBI chr  X:147,240,239...147,278,057 JBrowse link
G Gas1 growth arrest-specific 1 involved_in ISO (PMID:21357679) RGD PMID:21357679 NCBI chr17:4,482,014...4,485,155 JBrowse link
G Glg1 golgi glycoprotein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:4829764|MGI:97513 (MGI:4829577|PMID:20530870)
Ensembl
RGD
PMID:20530870 GO_REF:0000107 MGI:4829577 NCBI chr19:39,124,892...39,224,178 JBrowse link
G Il1r2 interleukin 1 receptor type 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:5468848|PMID:23395675)
Ensembl
RGD
PMID:23395675 GO_REF:0000107 MGI:5468848 NCBI chr 9:42,384,280...42,424,726 JBrowse link
G LOC100910107 ubiquitin carboxyl-terminal hydrolase DUB-1-like involved_in ISO (PMID:19188362) RGD PMID:19188362 NCBI chr 1:159,151,417...159,155,192 JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (PMID:21370995) RGD PMID:21370995 NCBI chr 7:122,826,712...122,987,711 JBrowse link
G Mdm2 MDM2 proto-oncogene IMP caspase-3 RGD PMID:19638633 RGD:2317364 NCBI chr 7:53,290,660...53,315,205 JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A IMP Casp3 RGD PMID:21925170 RGD:9999170 NCBI chr 1:96,000,053...96,003,128 JBrowse link
G Snx12 sorting nexin 12 involved_in ISO (PMID:22709416) RGD PMID:22709416 NCBI chr  X:66,226,995...66,356,945 JBrowse link
G Tmem59 transmembrane protein 59 involved_in ISO (PMID:20427278) RGD PMID:20427278 NCBI chr 5:121,962,507...121,983,625 JBrowse link
G Tmem98 transmembrane protein 98 involved_in ISS
ISO
GO_REF:0000024
(MGI:6258499|PMID:30249802)
UniProt
RGD
PMID:30249802 GO_REF:0000024 MGI:6258499 NCBI chr10:65,796,173...65,807,082 JBrowse link
negative regulation of protein processing involved in protein targeting to mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sirt4 sirtuin 4 IMP RGD PMID:24029877 RGD:9586053 NCBI chr12:41,125,533...41,139,440 JBrowse link
zymogen inhibition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Furin furin (paired basic amino acid cleaving enzyme) involved_in ISO (PMID:11799113), (PMID:9130696) RGD PMID:9130696 PMID:11799113 NCBI chr 1:134,348,142...134,361,182 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    negative regulation of biological process 5618
      negative regulation of metabolic process 3185
        negative regulation of macromolecule metabolic process 2961
          negative regulation of gene expression 1117
            negative regulation of protein maturation 29
              negative regulation of N-terminal peptidyl-lysine acetylation 0
              negative regulation of N-terminal peptidyl-methionine acetylation 0
              negative regulation of protein processing + 29
Path 2
Term Annotations click to browse term
  biological_process 19492
    metabolic process 11795
      organic substance metabolic process 11334
        macromolecule metabolic process 9790
          gene expression 6288
            regulation of gene expression 4820
              negative regulation of gene expression 1117
                negative regulation of protein maturation 29
                  negative regulation of N-terminal peptidyl-lysine acetylation 0
                  negative regulation of N-terminal peptidyl-methionine acetylation 0
                  negative regulation of protein processing + 29
paths to the root