Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of regulated secretory pathway
go back to main search page
Accession:GO:1903307 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of regulated secretory pathway.
Comment:An example of this is protein domain-specific expression of Synaptotagmin 1 in rat (P21707) in PMID:12526776 inferred from mutant phenotype.
Synonyms:exact_synonym: up regulation of regulated secretory pathway;   upregulation of regulated secretory pathway
 narrow_synonym: activation of regulated secretory pathway



show annotations for term's descendants           Sort by:
 
positive regulation of regulated secretory pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RAB15 RAB15, member RAS oncogene family involved_in ISO (PMID:22899725) UniProt PMID:22899725 NCBI chr 8:39,329,754...39,364,000
Ensembl chr 8:39,330,557...39,335,590
JBrowse link
G RAB27A RAB27A, member RAS oncogene family involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:20,633,576...20,706,240
Ensembl chr30:20,635,400...20,690,521
JBrowse link
G RAB3A RAB3A, member RAS oncogene family involved_in ISO (PMID:22899725) UniProt PMID:22899725 NCBI chr20:44,796,740...44,802,224
Ensembl chr20:44,796,895...44,801,692
JBrowse link
G RAB3D RAB3D, member RAS oncogene family involved_in ISO (PMID:22899725) UniProt PMID:22899725 NCBI chr20:49,974,592...49,985,362
Ensembl chr20:49,974,590...49,983,062
JBrowse link
G UNC13D unc-13 homolog D involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:4,753,300...4,766,751
Ensembl chr 9:4,753,166...4,766,756
JBrowse link
induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1D calcium voltage-gated channel subunit alpha1 D involved_in IEA GOC GO_REF:0000108 NCBI chr20:36,189,986...36,488,460
Ensembl chr20:36,191,810...36,613,686
JBrowse link
positive regulation of acrosomal vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HYAL3 hyaluronidase 3 involved_in ISO (MGI:4834982|PMID:20586096) UniProt PMID:20586096 MGI:4834982 NCBI chr20:39,041,940...39,047,388
Ensembl chr20:39,042,070...39,047,365
JBrowse link
G ZP3 zona pellucida glycoprotein 3 involved_in ISS UniProt GO_REF:0000024 NCBI chr 6:7,586,212...7,594,610
Ensembl chr 6:7,585,970...7,594,610
JBrowse link
positive regulation of calcium ion-dependent exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARF1 ADP ribosylation factor 1 ISO RGD PMID:10657240 RGD:9684853 NCBI chr14:835,476...836,424
Ensembl chr14:835,476...836,424
JBrowse link
G CACNA1G calcium voltage-gated channel subunit alpha1 G ISO RGD PMID:17172292 RGD:2316206 NCBI chr 9:26,481,148...26,544,511
Ensembl chr 9:26,481,652...26,544,845
JBrowse link
G CADPS calcium dependent secretion activator ISO RGD PMID:9289490 RGD:1299539 NCBI chr20:28,221,150...28,680,844
Ensembl chr20:28,221,843...28,680,131
JBrowse link
G CDK5 cyclin dependent kinase 5 acts_upstream_of_or_within ISO (MGI:3709145|PMID:15123626) MGI PMID:15123626 MGI:3709145 NCBI chr16:15,105,177...15,113,085
Ensembl chr16:15,101,230...15,109,269
JBrowse link
G CDK5R2 cyclin dependent kinase 5 regulatory subunit 2 acts_upstream_of_or_within ISO (MGI:3709145|PMID:15123626) MGI PMID:15123626 MGI:3709145 NCBI chr37:25,528,934...25,535,795
Ensembl chr37:25,529,151...25,530,263
JBrowse link
G DOC2B double C2 domain beta involved_in ISO PMID:18596155 UniProt PMID:18596155 RGD:8554556 NCBI chr 9:45,450,270...45,488,638
Ensembl chr 9:45,450,302...45,485,247
JBrowse link
G KCNB1 potassium voltage-gated channel subfamily B member 1 involved_in ISO PMID:17301173
PMID:18167541
PMID:20484665
UniProt PMID:17301173 PMID:18167541 PMID:20484665 RGD:10047179 RGD:10047360 RGD:10047384 NCBI chr24:36,016,800...36,118,873
Ensembl chr24:36,025,472...36,117,934
JBrowse link
G SCAMP5 secretory carrier membrane protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:38,007,967...38,029,541
Ensembl chr30:38,008,035...38,030,881
JBrowse link
G STX1A syntaxin 1A involved_in ISO PMID:17301173
PMID:20484665
PMID:18167541
UniProt PMID:17301173 PMID:18167541 PMID:20484665 RGD:10047179 RGD:10047360 RGD:10047384 NCBI chr 6:6,574,616...6,583,002
Ensembl chr 6:6,574,631...6,581,833
JBrowse link
G STXBP1 syntaxin binding protein 1 acts_upstream_of_or_within ISO (MGI:3709145|PMID:15123626) MGI PMID:15123626 MGI:3709145 NCBI chr 9:55,690,939...55,768,008
Ensembl chr 9:55,678,264...55,727,680
JBrowse link
G SYT1 synaptotagmin 1 ISO RGD PMID:21551071 RGD:7205660 NCBI chr15:21,629,061...22,042,734
Ensembl chr15:21,834,763...22,042,732
JBrowse link
G SYT10 synaptotagmin 10 involved_in ISO (MGI:5751674|PMID:21496647) UniProt PMID:21496647 MGI:5751674 NCBI chr27:15,593,709...15,657,184
Ensembl chr27:15,593,649...15,687,920
JBrowse link
G SYT7 synaptotagmin 7 ISO RGD PMID:21551071 RGD:7205660 NCBI chr18:54,863,072...54,926,121
Ensembl chr18:54,861,754...54,921,367
JBrowse link
G SYT9 synaptotagmin 9 ISO RGD PMID:21551071 RGD:7205660 NCBI chr21:30,985,059...31,123,986
Ensembl chr21:30,986,521...31,162,414
JBrowse link
positive regulation of calcium ion-dependent exocytosis of neurotransmitter term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SYT1 synaptotagmin 1 involved_in ISO (MGI:2179533|PMID:11242035) UniProt PMID:11242035 MGI:2179533 NCBI chr15:21,629,061...22,042,734
Ensembl chr15:21,834,763...22,042,732
JBrowse link
positive regulation of dense core granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SYT4 synaptotagmin 4 involved_in ISO (MGI:3795609|PMID:18468511) ParkinsonsUK-UCL PMID:18468511 MGI:3795609 NCBI chr 7:47,555,110...47,565,313
Ensembl chr 7:47,509,852...47,563,714
JBrowse link
positive regulation of eosinophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2RL1 F2R like trypsin receptor 1 involved_in ISO (PMID:11714832) UniProt PMID:11714832 NCBI chr 3:29,801,119...29,810,006
Ensembl chr 3:29,800,211...29,810,180
JBrowse link
G STX4 syntaxin 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:17,184,044...17,189,481
Ensembl chr 6:17,184,399...17,189,370
JBrowse link
positive regulation of histamine secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NPPA natriuretic peptide A involved_in ISO PMID:9663691 UniProt PMID:9663691 RGD:13461752 NCBI chr 2:84,406,317...84,408,115
Ensembl chr 2:84,396,073...84,408,385
JBrowse link
G PLA2G3 phospholipase A2 group III involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:24,127,074...24,132,508
Ensembl chr26:24,128,005...24,132,508
JBrowse link
G SNX4 sorting nexin 4 involved_in ISO (PMID:18253931) UniProt PMID:18253931 NCBI chr33:28,413,586...28,468,546
Ensembl chr33:28,419,128...28,469,488
JBrowse link
G VAMP7 vesicle associated membrane protein 7 involved_in ISO (PMID:18253931) UniProt PMID:18253931 NCBI chr  X:123,717,524...123,783,781
Ensembl chr  X:123,717,446...123,783,014
JBrowse link
G VAMP8 vesicle associated membrane protein 8 involved_in ISO (PMID:18253931) UniProt PMID:18253931 NCBI chr17:39,497,628...39,501,734
Ensembl chr17:39,497,785...39,501,739
JBrowse link
positive regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2B adenosine A2b receptor acts_upstream_of_or_within ISO (MGI:3776334|PMID:11454903) MGI PMID:11454903 MGI:3776334 NCBI chr 5:39,884,375...39,908,214 JBrowse link
G ADORA3 adenosine A3 receptor acts_upstream_of_or_within ISO (MGI:2664591|PMID:12817016) MGI PMID:12817016 MGI:2664591 NCBI chr17:63,895,408...63,898,666
Ensembl chr17:63,895,408...63,898,666
JBrowse link
G CRHR1 corticotropin releasing hormone receptor 1 ISO RGD PMID:18209484 RGD:5130941 NCBI chr 9:9,708,696...9,763,281
Ensembl chr 9:9,714,204...9,763,402
JBrowse link
G FCER1A Fc epsilon receptor Ia acts_upstream_of_or_within ISO (MGI:85068|PMID:9000133) MGI PMID:9000133 MGI:85068 NCBI chr38:22,683,478...22,688,842
Ensembl chr38:22,683,477...22,690,763
JBrowse link
G FCER1G Fc epsilon receptor Ig involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3029067|PMID:14764707) Ensembl
MGI
PMID:14764707 GO_REF:0000107 MGI:3029067 NCBI chr38:21,267,841...21,271,036
Ensembl chr38:21,268,001...21,270,940
JBrowse link
G FGR FGR proto-oncogene, Src family tyrosine kinase involved_in ISO (MGI:5294498|PMID:21746961) UniProt PMID:21746961 MGI:5294498 NCBI chr 2:72,678,858...72,692,417
Ensembl chr 2:72,680,675...72,690,251
JBrowse link
G GATA1 GATA binding protein 1 ISO RGD PMID:22390417 RGD:9587812 NCBI chr  X:41,991,321...41,998,319
Ensembl chr  X:41,971,582...41,998,303
JBrowse link
G GATA2 GATA binding protein 2 ISO RGD PMID:22390417 RGD:9587812 NCBI chr20:2,472,251...2,488,380
Ensembl chr20:2,473,912...2,480,991
JBrowse link
G IL13 interleukin 13 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3589858|PMID:15944273) Ensembl
MGI
PMID:15944273 GO_REF:0000107 MGI:3589858 NCBI chr11:20,957,870...20,961,391
Ensembl chr11:20,958,464...20,961,388
JBrowse link
G IL4 interleukin 4 involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:3589858|PMID:15944273)
GO_Central
MGI
PMID:15944273 PMID:21873635 MGI:3589858 NCBI chr11:20,972,693...20,981,539
Ensembl chr11:20,972,690...20,981,534
JBrowse link
G IL4R interleukin 4 receptor acts_upstream_of_or_within ISO (MGI:3589858|PMID:15944273) MGI PMID:15944273 MGI:3589858 NCBI chr 6:19,254,183...19,280,973
Ensembl chr 6:19,254,487...19,389,291
JBrowse link
G MS4A2 membrane spanning 4-domains A2 ISO RGD PMID:16177098 RGD:1578516 NCBI chr21:50,439,133...50,456,785
Ensembl chr21:50,450,024...50,456,785
JBrowse link
G NARS2 asparaginyl-tRNA synthetase 2, mitochondrial involved_in ISO (MGI:2137187|PMID:11449275) UniProt PMID:11449275 MGI:2137187 NCBI chr21:20,277,707...20,413,624
Ensembl chr21:20,277,507...20,606,736
JBrowse link
G NPPC natriuretic peptide C involved_in ISO PMID:9663691 UniProt PMID:9663691 RGD:13461752 NCBI chr25:43,714,545...43,718,969
Ensembl chr25:43,717,939...43,718,996
JBrowse link
G PLD2 phospholipase D2 ISO RGD PMID:16861349 RGD:2299903 NCBI chr 5:31,755,881...31,767,131
Ensembl chr 5:31,756,433...31,767,066
JBrowse link
G SPHK2 sphingosine kinase 2 involved_in ISO (MGI:3703830|PMID:17346996) UniProt PMID:17346996 MGI:3703830 NCBI chr 1:107,681,425...107,689,790
Ensembl chr 1:107,680,599...107,689,707
JBrowse link
G STXBP1 syntaxin binding protein 1 ISO RGD PMID:23487749 RGD:12904029 NCBI chr 9:55,690,939...55,768,008
Ensembl chr 9:55,678,264...55,727,680
JBrowse link
G STXBP2 syntaxin binding protein 2 ISO RGD PMID:23487749 RGD:12904029 NCBI chr20:52,413,174...52,421,525
Ensembl chr20:52,413,191...52,421,517
JBrowse link
G SYK spleen associated tyrosine kinase acts_upstream_of_or_within ISO (MGI:85068|PMID:9000133) RGD
MGI
PMID:9000133 PMID:16861349 MGI:85068 RGD:2299903 NCBI chr 1:95,903,501...95,955,577
Ensembl chr 1:95,903,566...95,955,583
JBrowse link
positive regulation of natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AP1G1 adaptor related protein complex 1 subunit gamma 1 involved_in ISO (PMID:23632890) UniProt PMID:23632890 NCBI chr 5:77,512,865...77,589,136
Ensembl chr 5:77,432,517...77,565,801
JBrowse link
G CD160 CD160 molecule involved_in ISO (PMID:19109136) UniProt PMID:19109136 NCBI chr17:58,548,137...58,564,077
Ensembl chr17:58,555,851...58,563,341
JBrowse link
G DLA-79 MHC class Ib involved_in ISO (PMID:27455421) UniProt PMID:27455421 NCBI chr18:41,142,312...41,170,018
Ensembl chr18:41,142,307...41,170,100
JBrowse link
G LAMP1 lysosomal associated membrane protein 1 involved_in ISO (PMID:23632890) UniProt PMID:23632890 NCBI chr22:60,678,116...60,695,619
Ensembl chr22:60,678,111...60,694,924
JBrowse link
G LOC486692 NKG2-A/NKG2-B type II integral membrane protein-like involved_in ISO (PMID:21825173) UniProt PMID:21825173 NCBI chr27:35,534,620...35,584,473 JBrowse link
positive regulation of neutrophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD177 CD177 molecule involved_in ISO (PMID:21193407) UniProt PMID:21193407 NCBI chr 1:111,693,234...111,698,879
Ensembl chr 1:111,693,005...111,698,742
JBrowse link
G ITGAM integrin subunit alpha M involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:16,944,062...16,996,525
Ensembl chr 6:16,808,971...16,996,286
JBrowse link
G ITGB2 integrin subunit beta 2 involved_in ISO (PMID:21193407) UniProt PMID:21193407 NCBI chr31:38,520,733...38,547,003
Ensembl chr31:38,521,103...38,547,018
JBrowse link
G PTAFR platelet activating factor receptor ISO RGD PMID:2829894 RGD:10041060 NCBI chr 2:72,225,386...72,256,353
Ensembl chr 2:72,225,386...72,256,352
JBrowse link
positive regulation of synaptic vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL2L1 BCL2 like 1 involved_in ISO PMID:23792689 CAFA PMID:23792689 RGD:12793033 NCBI chr24:21,145,214...21,209,425
Ensembl chr24:21,145,215...21,196,355
JBrowse link
G DNM1L dynamin 1 like involved_in ISO PMID:23792689 CAFA PMID:23792689 RGD:12793033 NCBI chr27:16,161,855...16,211,983
Ensembl chr27:16,163,357...16,211,957
JBrowse link
G NLGN1 neuroligin 1 involved_in ISO PMID:19628693
(MGI:4355770|PMID:19628693)
BHF-UCL PMID:19628693 MGI:4355770 RGD:8554760 NCBI chr34:37,397,772...38,203,634
Ensembl chr34:37,572,629...38,203,177
JBrowse link
G SLC4A8 solute carrier family 4 member 8 acts_upstream_of_or_within ISO (MGI:5013899|PMID:21593314) ARUK-UCL PMID:21593314 MGI:5013899 NCBI chr27:3,398,776...3,460,562
Ensembl chr27:3,403,804...3,460,583
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 13969
    positive regulation of biological process 6063
      positive regulation of cellular process 5598
        positive regulation of secretion by cell 360
          positive regulation of exocytosis 98
            positive regulation of regulated secretory pathway 61
              positive regulation of calcium ion-dependent exocytosis + 17
              positive regulation of leukocyte degranulation + 35
              positive regulation of synaptic vesicle exocytosis + 6
Path 2
Term Annotations click to browse term
  biological_process 13969
    localization 5461
      establishment of localization 3975
        transport 3816
          secretion 1036
            secretion by cell 879
              exocytosis 365
                regulated exocytosis 265
                  regulation of regulated secretory pathway 174
                    positive regulation of regulated secretory pathway 61
                      positive regulation of calcium ion-dependent exocytosis + 17
                      positive regulation of leukocyte degranulation + 35
                      positive regulation of synaptic vesicle exocytosis + 6
paths to the root