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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of tumor necrosis factor-mediated signaling pathway
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Accession:GO:1903265 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of tumor necrosis factor-mediated signaling pathway.
Synonyms:exact_synonym: positive regulation of tumor necrosis factor-mediated signalling pathway;   up regulation of tumor necrosis factor-mediated signaling pathway;   up regulation of tumor necrosis factor-mediated signalling pathway;   upregulation of tumor necrosis factor-mediated signaling pathway;   upregulation of tumor necrosis factor-mediated signalling pathway
 narrow_synonym: activation of TNF-alpha-mediated signaling pathway;   activation of tumor necrosis factor alpha-mediated signaling pathway;   activation of tumor necrosis factor-mediated signaling pathway;   activation of tumor necrosis factor-mediated signalling pathway;   positive regulation of TNF-alpha-mediated signaling pathway;   positive regulation of tumor necrosis factor alpha-mediated signaling pathway;   up regulation of TNF-alpha-mediated signaling pathway;   up regulation of tumor necrosis factor alpha-mediated signaling pathway;   upregulation of TNF-alpha-mediated signaling pathway;   upregulation of tumor necrosis factor alpha-mediated signaling pathway
 related_synonym: activation of adipocytokine signaling pathway;   positive regulation of adipocytokine signaling pathway;   up regulation of adipocytokine signaling pathway;   upregulation of adipocytokine signaling pathway



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positive regulation of tumor necrosis factor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 ADAM metallopeptidase domain 17 involved_in ISO
IEA
(PMID:24813629)
GO_REF:0000107
RGD
Ensembl
PMID:24813629 GO_REF:0000107 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639
JBrowse link
G Casp1 caspase 1 involved_in ISO (PMID:16920334) RGD PMID:16920334 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp4 caspase 4 involved_in ISO (PMID:16920334) RGD PMID:16920334 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
JBrowse link
G Cpne1 copine 1 involved_in ISO
IEA
IBA
(PMID:14674885)
GO_REF:0000107
GO_REF:0000033
RGD
Ensembl
GO_Central
PMID:14674885 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:144,587,531...144,629,911
Ensembl chr 3:144,588,995...144,598,636
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO UniProtKB:Q9HC29 (PMID:24790089) RGD PMID:24790089 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO UniProtKB:Q9HC29 (PMID:24790089) RGD PMID:24790089 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (MGI:6391873|PMID:22733818) RGD PMID:22733818 MGI:6391873 NCBI chr 5:143,087,759...143,109,807
Ensembl chr 5:143,087,759...143,109,807
JBrowse link
G Mmp8 matrix metallopeptidase 8 involved_in IEA
ISS
ISO
GO_REF:0000107
PMID:25049354
(MGI:6201889|PMID:25049354)
Ensembl
RGD
PMID:25049354 PMID:25049354 GO_REF:0000107 MGI:6201889, RGD:13792525 NCBI chr 8:4,724,009...4,733,864
Ensembl chr 8:4,724,029...4,733,520
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
ISS
IEA
(PMID:23453807)
GO_REF:0000024
GO_REF:0000107
RGD
ParkinsonsUK-UCL
Ensembl
PMID:23453807 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
JBrowse link
G Rbm12 RNA binding motif protein 12 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 3:144,609,661...144,629,911
Ensembl chr 3:144,611,623...144,629,915
Ensembl chr 3:144,611,623...144,629,915
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in ISO (MGI:6271183|PMID:30439713) RGD PMID:30439713 MGI:6271183 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824
JBrowse link
G Traf2 Tnf receptor-associated factor 2 involved_in ISO (MGI:5616328|PMID:11374864) RGD PMID:11374864 MGI:5616328 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538
JBrowse link
G Trim32 tripartite motif-containing 32 acts_upstream_of_or_within ISO (PMID:20054338) RGD PMID:20054338 NCBI chr 5:79,005,139...79,016,615
Ensembl chr 5:78,999,389...79,022,018
JBrowse link
G Ube2k ubiquitin-conjugating enzyme E2K involved_in ISO (PMID:26707646) RGD PMID:26707646 NCBI chr14:42,658,016...42,718,899
Ensembl chr14:42,658,016...42,718,630
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    cellular process 18812
      signal transduction 7209
        positive regulation of signal transduction 1754
          positive regulation of cytokine-mediated signaling pathway 59
            positive regulation of tumor necrosis factor-mediated signaling pathway 14
Path 2
Term Annotations click to browse term
  biological_process 20413
    biological regulation 13755
      regulation of biological process 13322
        signaling 7775
          signal transduction 7209
            cell surface receptor signaling pathway 2886
              cytokine-mediated signaling pathway 492
                regulation of cytokine-mediated signaling pathway 164
                  positive regulation of cytokine-mediated signaling pathway 59
                    positive regulation of tumor necrosis factor-mediated signaling pathway 14
paths to the root