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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of tumor necrosis factor-mediated signaling pathway
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Accession:GO:1903265 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of tumor necrosis factor-mediated signaling pathway.
Synonyms:exact_synonym: positive regulation of tumor necrosis factor-mediated signalling pathway;   up regulation of tumor necrosis factor-mediated signaling pathway;   up regulation of tumor necrosis factor-mediated signalling pathway;   upregulation of tumor necrosis factor-mediated signaling pathway;   upregulation of tumor necrosis factor-mediated signalling pathway
 narrow_synonym: activation of TNF-alpha-mediated signaling pathway;   activation of tumor necrosis factor alpha-mediated signaling pathway;   activation of tumor necrosis factor-mediated signaling pathway;   activation of tumor necrosis factor-mediated signalling pathway;   positive regulation of TNF-alpha-mediated signaling pathway;   positive regulation of tumor necrosis factor alpha-mediated signaling pathway;   up regulation of TNF-alpha-mediated signaling pathway;   up regulation of tumor necrosis factor alpha-mediated signaling pathway;   upregulation of TNF-alpha-mediated signaling pathway;   upregulation of tumor necrosis factor alpha-mediated signaling pathway
 related_synonym: activation of adipocytokine signaling pathway;   positive regulation of adipocytokine signaling pathway;   up regulation of adipocytokine signaling pathway;   upregulation of adipocytokine signaling pathway


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positive regulation of tumor necrosis factor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM17 ADAM metallopeptidase domain 17 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:9,478,080...9,545,363
Ensembl chr2A:9,641,201...9,708,054 		JBrowse link
G CASP1 caspase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:99,965,964...99,975,640
Ensembl chr11:103,448,497...103,458,149
Ensembl chr11:103,448,497...103,458,149 		JBrowse link
G CASP4 caspase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:99,883,353...99,909,185
Ensembl chr11:103,366,138...103,391,824 		JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:24790089) UniProt PMID:24790089 NCBI chr 6:31,476,710...31,491,411 JBrowse link
G HSPA1B heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:24790089) UniProt PMID:24790089 NCBI chr 6:31,488,882...31,491,412 JBrowse link
G LAPTM5 lysosomal protein transmembrane 5 involved_in ISO (MGI:6391873|PMID:22733818) ARUK-UCL PMID:22733818 MGI:6391873 NCBI chr 1:30,005,941...30,031,366
Ensembl chr 1:31,032,963...31,058,385 		JBrowse link
G MMP8 matrix metallopeptidase 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:97,650,408...97,663,731
Ensembl chr11:101,143,268...101,156,736 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770 		JBrowse link
G RBM12 RNA binding motif protein 12 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr20:31,951,508...31,990,489
Ensembl chr20:33,069,932...33,108,547 		JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:2,893,802...2,943,162
Ensembl chr 6:2,997,343...3,045,078 		JBrowse link
G TRAF2 TNF receptor associated factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:107,938,935...107,984,797
Ensembl chr 9:136,917,358...136,955,331 		JBrowse link
G TRIM32 tripartite motif containing 32 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20054338) Ensembl
MGI		 PMID:20054338 GO_REF:0000107 NCBI chr 9:87,819,723...87,838,684
Ensembl chr 9:116,183,746...116,185,707 		JBrowse link
G UBE2K ubiquitin conjugating enzyme E2 K involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:34,026,942...34,111,923
Ensembl chr 4:39,877,966...39,960,397 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16440
    cellular process 15499
      signal transduction 5440
        positive regulation of signal transduction 1642
          positive regulation of cytokine-mediated signaling pathway 59
            positive regulation of tumor necrosis factor-mediated signaling pathway 13
Path 2
Term Annotations click to browse term
  biological_process 16440
    biological regulation 11453
      regulation of biological process 11104
        signaling 5935
          signal transduction 5440
            cell surface receptor signaling pathway 2631
              cytokine-mediated signaling pathway 442
                regulation of cytokine-mediated signaling pathway 150
                  positive regulation of cytokine-mediated signaling pathway 59
                    positive regulation of tumor necrosis factor-mediated signaling pathway 13
paths to the root