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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of oxidative stress-induced cell death
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Accession:GO:1903202 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of oxidative stress-induced cell death.
Synonyms:exact_synonym: down regulation of cell death in response to oxidative stress;   downregulation of cell death in response to oxidative stress;   negative regulation of cell death in response to oxidative stress
 narrow_synonym: inhibition of cell death in response to oxidative stress
 related_synonym: protection against oxidative stress-induced cell death


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negative regulation of oxidative stress-induced cell death term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fyn FYN proto-oncogene, Src family tyrosine kinase involved_in IMP PMID:27525436 ARUK-UCL PMID:27525436 RGD:13601987 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911 		JBrowse link
G Gata4 GATA binding protein 4 involved_in ISO (MGI:5780531|PMID:25590961) RGD PMID:25590961 MGI:5780531 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636 		JBrowse link
G Mir29b1 microRNA 29b-1 involved_in ISO (PMID:19956414) RGD PMID:19956414 NCBI chr 4:59,650,987...59,651,067
Ensembl chr 4:59,650,986...59,651,067 		JBrowse link
G Mir29b2 microRNA 29b-2 involved_in ISO (PMID:19956414) RGD PMID:19956414 NCBI chr13:106,570,371...106,570,451
Ensembl chr13:106,570,367...106,570,456 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO (PMID:16632486) RGD PMID:16632486 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:16632486) RGD PMID:16632486 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
negative regulation of hydrogen peroxide-induced cell death term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpr37 G protein-coupled receptor 37 involved_in ISO (MGI:5586790|PMID:23690594) RGD PMID:23690594 MGI:5586790 NCBI chr 4:54,138,860...54,160,927
Ensembl chr 4:54,138,870...54,161,001 		JBrowse link
G Gpr37l1 G protein-coupled receptor 37-like 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5586790|PMID:23690594)		 Ensembl
RGD		 PMID:23690594 GO_REF:0000107 MGI:5586790 NCBI chr13:46,598,574...46,605,421
Ensembl chr13:46,598,578...46,605,421 		JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (PMID:24576675) RGD PMID:24576675 NCBI chr 7:122,826,712...122,987,711
Ensembl chr 7:122,826,696...122,987,703 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 involved_in ISO UniProtKB:Q99497 (PMID:22492997) RGD PMID:22492997 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO (PMID:22492997), (PMID:23743200) RGD PMID:22492997 PMID:23743200 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Pde8a phosphodiesterase 8A involved_in ISO (PMID:23509299) UniProt PMID:23509299 NCBI chr 1:135,166,143...135,288,986
Ensembl chr 1:135,166,237...135,288,024 		JBrowse link
G Psap prosaposin involved_in ISO (MGI:5586790|PMID:23690594) RGD PMID:23690594 MGI:5586790 NCBI chr20:28,214,229...28,240,501
Ensembl chr20:28,214,271...28,240,498 		JBrowse link
G Pycr1 pyrroline-5-carboxylate reductase 1 involved_in ISO (PMID:23743200) RGD PMID:23743200 NCBI chr10:105,917,732...105,922,658
Ensembl chr10:105,917,680...105,922,549 		JBrowse link
G Txn1 thioredoxin 1 involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:Q99497 (PMID:22492997)		 Ensembl
RGD		 PMID:22492997 GO_REF:0000107 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629 		JBrowse link
negative regulation of hydrogen peroxide-induced neuron death term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxo7 F-box protein 7 involved_in ISO (PMID:26310625) RGD PMID:26310625 NCBI chr 7:17,809,224...17,837,549
Ensembl chr 7:17,809,231...17,837,530 		JBrowse link
G Il10 interleukin 10 involved_in ISO ComplexPortal:CPX-1134 (MGI:5291547|PMID:21857966) RGD PMID:21857966 MGI:5291547 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO (PMID:15983381), (PMID:24947010)
(MGI:5574514|PMID:24947010)		 RGD PMID:15983381 PMID:24947010 MGI:5574514 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Rack1 receptor for activated C kinase 1 involved_in ISO
IEA		 UniProtKB:Q99497 (PMID:24947010)
GO_REF:0000107
UniProtKB:Q99497 (MGI:5574514|PMID:24947010)		 RGD
Ensembl		 PMID:24947010 GO_REF:0000107 MGI:5574514 NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975 		JBrowse link
negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase involved_in ISO UniProtKB:Q99LX0 (PMID:14652021)
(MGI:5613479|PMID:14652021)		 RGD PMID:14652021 MGI:5613479 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:21177249), (PMID:23261939) RGD PMID:21177249 PMID:23261939 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
negative regulation of hydrogen peroxide-mediated programmed cell death term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddr2 discoidin domain receptor tyrosine kinase 2 IMP RGD PMID:32412792 RGD:150429761 NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363 		JBrowse link
G Glrx glutaredoxin IMP RGD PMID:19938943 RGD:9686063 NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680 		JBrowse link
G Hgf hepatocyte growth factor involved_in ISO (PMID:20655899) RGD PMID:20655899 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409 		JBrowse link
G Hk3 hexokinase 3 involved_in IDA PMID:21072205 CACAO PMID:21072205 RGD:10047370 NCBI chr17:9,596,950...9,614,847
Ensembl chr17:9,599,865...9,614,863 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase involved_in ISO
IEA		 (PMID:20655899)
GO_REF:0000107		 RGD
Ensembl		 PMID:20655899 GO_REF:0000107 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876 		JBrowse link
G Mir132 microRNA 132 IMP RGD PMID:23585551 RGD:7327146 NCBI chr10:60,023,696...60,023,796
Ensembl chr10:60,023,696...60,023,796 		JBrowse link
G Mir21 microRNA 21 IMP RGD PMID:19336275 RGD:41404719 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir212 microRNA 212 IMP RGD PMID:23585551 RGD:7327146 NCBI chr10:60,023,403...60,023,513
Ensembl chr10:60,023,403...60,023,513 		JBrowse link
G Mirlet7b microRNA let-7b involved_in ISO (PMID:26296645) RGD PMID:26296645 NCBI chr 7:116,804,186...116,804,270
Ensembl chr 7:116,804,186...116,804,270 		JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsph1 heat shock protein family H (Hsp110) member 1 acts_upstream_of_or_within ISO (MGI:3822965|PMID:18681888) RGD PMID:18681888 MGI:3822965 NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO
IMP		 (PMID:17579517) RGD PMID:17579517 PMID:17579517 RGD:8693356 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
G Trap1 TNF receptor-associated protein 1 involved_in IMP PMID:17579517 ParkinsonsUK-UCL PMID:17579517 RGD:8693356 NCBI chr10:11,464,882...11,498,931
Ensembl chr10:11,464,821...11,498,981 		JBrowse link
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag5 BAG cochaperone 5 involved_in ISO (PMID:24475098) RGD PMID:24475098 NCBI chr 6:130,768,467...130,772,122
Ensembl chr 6:130,768,141...130,772,970 		JBrowse link
G Gpx1 glutathione peroxidase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2158814 (MGI:3698597|PMID:16373599)		 Ensembl
RGD		 PMID:16373599 GO_REF:0000107 MGI:3698597 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:3581090|PMID:15731106)		 Ensembl
RGD		 PMID:15731106 GO_REF:0000107 MGI:3581090 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Mapk7 mitogen-activated protein kinase 7 involved_in ISO
IEA		 (PMID:23043106)
GO_REF:0000107		 RGD
Ensembl		 PMID:23043106 GO_REF:0000107 NCBI chr10:46,170,264...46,176,262
Ensembl chr10:46,170,167...46,176,267 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 involved_in ISO (PMID:23043106) RGD PMID:23043106 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nme5 NME/NM23 family member 5 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:2664629|PMID:12788088)		 RGD PMID:12788088 PMID:21873635 MGI:2664629, RGD:13792537 NCBI chr18:26,163,558...26,180,742
Ensembl chr18:26,163,555...26,180,794 		JBrowse link
G Nol3 nucleolar protein 3 involved_in ISO (PMID:15004034) RGD PMID:15004034 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250 		JBrowse link
G Park7 Parkinsonism associated deglycase acts_upstream_of ISO (PMID:22523093)
(MGI:5582151|PMID:22523093)		 RGD PMID:22523093 MGI:5582151 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Ppia peptidylprolyl isomerase A involved_in ISO
ISS		 (PMID:26095851)
GO_REF:0000024		 RGD
UniProt		 PMID:26095851 GO_REF:0000024 NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601 		JBrowse link
G Ppial4d peptidylprolyl isomerase A (cyclophilin A)-like 4D involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr14:21,006,522...21,007,284
Ensembl chr14:21,006,538...21,007,310 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:17317627) RGD PMID:17317627 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Sod2 superoxide dismutase 2 involved_in ISO (PMID:12551919) RGD PMID:12551919 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
negative regulation of oxidative stress-induced neuron death term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf4 activating transcription factor 4 involved_in ISO
IMP		 UniProtKB:Q9ES19 (PMID:23392669) RGD PMID:23392669 PMID:23392669 RGD:10047168 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Ctnnb1 catenin beta 1 involved_in ISO
IEA		 (MGI:5770063|PMID:21752258)
GO_REF:0000107		 RGD
Ensembl		 PMID:21752258 GO_REF:0000107 MGI:5770063 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Fbxo7 F-box protein 7 involved_in ISO
IBA		 (PMID:25029497)
PMID:21873635		 RGD PMID:25029497 PMID:21873635 RGD:13792537 NCBI chr 7:17,809,224...17,837,549
Ensembl chr 7:17,809,231...17,837,530 		JBrowse link
G Fzd1 frizzled class receptor 1 involved_in ISO (MGI:5770063|PMID:21752258) RGD PMID:21752258 MGI:5770063 NCBI chr 4:29,310,303...29,314,701
Ensembl chr 4:29,310,091...29,312,643
Ensembl chr 4:29,310,091...29,312,643 		JBrowse link
G Oxr1 oxidation resistance 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 7:72,528,782...72,965,666
Ensembl chr 7:72,528,786...72,965,666 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO (MGI:5575789|PMID:24899725) RGD PMID:24899725 MGI:5575789 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in IGI PMID:23392669 ParkinsonsUK-UCL PMID:23392669 RGD:10047168 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Rest RE1-silencing transcription factor involved_in ISO (PMID:24670762) UniProt PMID:24670762 NCBI chr14:30,859,109...30,879,828
Ensembl chr14:30,862,553...30,894,354 		JBrowse link
G Wnt1 Wnt family member 1 involved_in ISO (MGI:5770063|PMID:21752258) RGD PMID:21752258 MGI:5770063 NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651 		JBrowse link
negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hif1a hypoxia inducible factor 1 subunit alpha involved_in ISO
IEA		 (PMID:24899725)
GO_REF:0000107		 RGD
Ensembl		 PMID:24899725 GO_REF:0000107 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Nono non-POU domain containing, octamer-binding involved_in ISO (PMID:15790595) RGD PMID:15790595 NCBI chr  X:66,554,131...66,571,992
Ensembl chr  X:66,554,098...66,571,952 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO
ISS		 (PMID:15790595)
GO_REF:0000024		 RGD
ParkinsonsUK-UCL		 PMID:15790595 GO_REF:0000024 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
ISS		 (PMID:17314283)
(MGI:5543313|PMID:23858059)
GO_REF:0000024		 RGD
ParkinsonsUK-UCL		 PMID:17314283 PMID:23858059 GO_REF:0000024 MGI:5543313 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19748
    cellular process 18161
      cell death 2222
        cell death in response to oxidative stress 95
          negative regulation of oxidative stress-induced cell death 47
            negative regulation of hydrogen peroxide-induced cell death + 24
            negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway + 18
            negative regulation of oxidative stress-induced neuron death + 14
Path 2
Term Annotations click to browse term
  biological_process 19748
    response to stimulus 10461
      response to stress 4174
        cellular response to stress 2123
          cellular response to chemical stress 438
            cellular response to oxidative stress 364
              cell death in response to oxidative stress 95
                regulation of oxidative stress-induced cell death 73
                  negative regulation of oxidative stress-induced cell death 47
                    negative regulation of hydrogen peroxide-induced cell death + 24
                    negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway + 18
                    negative regulation of oxidative stress-induced neuron death + 14
paths to the root