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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of calcium ion transmembrane transport
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Accession:GO:1903170 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transport.
Comment:human HRC regulates RYR2 and thus regulates transmembrane transport of calcium from SR to cytosol
Synonyms:exact_synonym: down regulation of calcium ion membrane transport;   down regulation of calcium ion transmembrane transport;   down regulation of transmembrane calcium transport;   downregulation of calcium ion membrane transport;   downregulation of calcium ion transmembrane transport;   downregulation of transmembrane calcium transport;   negative regulation of calcium ion membrane transport;   negative regulation of transmembrane calcium transport
 narrow_synonym: inhibition of calcium ion membrane transport;   inhibition of calcium ion transmembrane transport;   inhibition of transmembrane calcium transport



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negative regulation of calcium ion transmembrane transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHR aryl hydrocarbon receptor ISO RGD PMID:12193573 RGD:625678 NCBI chr14:31,743,704...31,793,484
Ensembl chr14:31,686,170...31,791,444
JBrowse link
G CBARP CACN subunit beta associated regulatory protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:57,554,162...57,559,126
Ensembl chr20:57,554,032...57,559,612
JBrowse link
G PTGER3 prostaglandin E receptor 3 ISO RGD PMID:10670413 RGD:10043333 NCBI chr 6:74,932,789...74,986,573 JBrowse link
negative regulation of calcium import into the mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 ISO RGD PMID:24601882 RGD:39128160 NCBI chr 8:72,317,399...72,335,686
Ensembl chr 8:72,317,869...72,335,193
JBrowse link
G VDAC1 voltage dependent anion channel 1 involved_in ISO (PMID:32047033) UniProt PMID:32047033 NCBI chr11:22,197,814...22,212,924
Ensembl chr11:22,197,949...22,212,924
JBrowse link
negative regulation of calcium ion export across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CALM2 calmodulin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:49,299,698...49,314,533
Ensembl chr10:49,299,897...49,314,457
JBrowse link
G CALM3 calmodulin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:109,284,729...109,294,491
Ensembl chr 1:109,286,155...109,294,391
JBrowse link
G YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon involved_in ISO (PMID:18029012) SynGO-UCL PMID:18029012 NCBI chr 9:45,506,830...45,562,081
Ensembl chr 9:45,507,282...45,562,086
JBrowse link
negative regulation of calcium ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAV1 caveolin 1 ISO RGD PMID:29069575 RGD:151347449 NCBI chr14:55,458,934...55,494,563
Ensembl chr14:55,461,048...55,492,935
JBrowse link
G MIR200C microRNA mir-200c involved_in ISO (PMID:29373717) BHF-UCL PMID:29373717 NCBI chr27:38,082,097...38,082,159
Ensembl chr27:38,082,091...38,082,169
JBrowse link
G MIR208A microRNA mir-208a involved_in ISO (PMID:27545043) BHF-UCL PMID:27545043 NCBI chr 8:3,636,919...3,636,987
Ensembl chr 8:3,636,919...3,636,987
JBrowse link
G MIR208B microRNA mir-208b involved_in ISO (PMID:27545043) BHF-UCL PMID:27545043 NCBI chr 8:3,665,163...3,665,236
Ensembl chr 8:3,665,163...3,665,236
JBrowse link
negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BIN1 bridging integrator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:23,503,934...23,534,407
Ensembl chr19:23,375,363...23,534,303
JBrowse link
G FBXO11 F-box protein 11 ISO RGD PMID:32988261 RGD:152176655 NCBI chr10:49,838,003...49,864,211
Ensembl chr10:49,838,776...49,925,064
JBrowse link
G REM1 RRAD and GEM like GTPase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:26078055) Ensembl
MGI
PMID:26078055 GO_REF:0000107 NCBI chr24:20,991,166...21,000,019
Ensembl chr24:20,990,745...20,999,740
JBrowse link
G SESTD1 SEC14 and spectrin domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:22,648,732...22,742,009
Ensembl chr36:22,651,570...22,741,997
JBrowse link
G UBR3 ubiquitin protein ligase E3 component n-recognin 3 ISO RGD PMID:32988261 RGD:152176655 NCBI chr36:14,537,900...14,723,942
Ensembl chr36:14,537,921...14,721,790
JBrowse link
negative regulation of calcium ion transmembrane transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PPP2CA protein phosphatase 2 catalytic subunit alpha ISO RGD PMID:15728831 RGD:8554004 NCBI chr11:22,388,327...22,410,052
Ensembl chr11:22,385,257...22,410,052
JBrowse link
negative regulation of calcium ion transport into cytosol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL2 BCL2 apoptosis regulator involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15613488) Ensembl
MGI
PMID:15613488 GO_REF:0000107 NCBI chr 1:13,733,849...13,900,653
Ensembl chr 1:13,731,406...13,900,658
JBrowse link
G CRSP-3 calcitonin receptor-stimulating peptide 3 involved_in ISO (PMID:16014619) UniProt PMID:16014619 NCBI chr21:37,676,841...37,680,643
Ensembl chr21:37,676,841...37,680,645
JBrowse link
G EPO erythropoietin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:8,994,211...8,995,954
Ensembl chr 6:8,994,211...8,996,144
JBrowse link
G TMBIM6 transmembrane BAX inhibitor motif containing 6 acts_upstream_of_or_within ISO (PMID:26582200) MGI PMID:26582200 NCBI chr27:4,921,606...4,944,830
Ensembl chr27:4,921,606...4,944,783
JBrowse link
negative regulation of release of sequestered calcium ion into cytosol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B9D2 B9 domain containing 2 ISO RGD PMID:12876066 RGD:731229 NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885
JBrowse link
G FCRL5 Fc receptor like 5 acts_upstream_of_or_within ISO (PMID:23509253) MGI PMID:23509253 NCBI chr 7:40,685,554...40,719,195
Ensembl chr 7:40,696,448...40,716,314
JBrowse link
G FKBP1A FKBP prolyl isomerase 1A NOT|involved_in ISO (PMID:12443530) BHF-UCL PMID:12443530 NCBI chr24:19,618,581...19,643,685
Ensembl chr24:19,618,558...19,643,046
JBrowse link
G FKBP1B FKBP prolyl isomerase 1B involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:18,534,295...18,544,973
Ensembl chr17:18,534,741...18,544,943
JBrowse link
G LOC119880472 peptidyl-prolyl cis-trans isomerase FKBP1B involved_in IEA Ensembl GO_REF:0000107
G NTSR1 neurotensin receptor 1 ISO RGD PMID:12084713 RGD:727385 NCBI chr24:46,576,690...46,615,192
Ensembl chr24:46,576,501...46,615,206
JBrowse link
G PRKCE protein kinase C epsilon involved_in ISO PMID:20383739 UniProt PMID:20383739 RGD:7206836 NCBI chr10:47,976,929...48,464,614
Ensembl chr10:47,976,768...48,535,296
JBrowse link
G TGFB2 transforming growth factor beta 2 ISO RGD PMID:12876066 RGD:731229 NCBI chr38:13,430,832...13,511,655
Ensembl chr38:13,429,148...13,510,242
JBrowse link
G TRDN triadin ISO RGD PMID:16176928 RGD:7327230 NCBI chr 1:62,402,763...62,762,717
Ensembl chr 1:62,402,642...62,762,722
JBrowse link
negative regulation of voltage-gated calcium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CABP1 calcium binding protein 1 ISO RGD PMID:17960496 RGD:7207144 NCBI chr26:16,492,484...16,523,265 JBrowse link
G CACNB3 calcium voltage-gated channel auxiliary subunit beta 3 ISO RGD PMID:15024042 RGD:13514097 NCBI chr27:5,705,587...5,714,620
Ensembl chr27:5,706,064...5,717,647
JBrowse link
G CBARP CACN subunit beta associated regulatory protein ISO RGD PMID:24751537 RGD:10047103 NCBI chr20:57,554,162...57,559,126
Ensembl chr20:57,554,032...57,559,612
JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 ISO RGD PMID:26584289 RGD:155804278 NCBI chr12:49,669,849...49,740,039
Ensembl chr12:49,672,389...49,739,850
JBrowse link
G OPRL1 opioid related nociceptin receptor 1 ISO RGD PMID:15937148 RGD:9835002 NCBI chr24:47,530,039...47,537,477
Ensembl chr24:47,508,136...47,537,250
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17878
    negative regulation of biological process 5711
      negative regulation of transport 531
        negative regulation of monoatomic ion transport 129
          negative regulation of calcium ion transport 59
            negative regulation of calcium ion transmembrane transport 35
              negative regulation of calcium import into the mitochondrion 2
              negative regulation of calcium ion export across plasma membrane 3
              negative regulation of calcium ion import across plasma membrane 4
              negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel 5
              negative regulation of calcium ion transmembrane transporter activity + 6
              negative regulation of calcium ion transport into cytosol + 4
              negative regulation of release of sequestered calcium ion into cytosol + 9
Path 2
Term Annotations click to browse term
  biological_process 17878
    localization 5577
      establishment of localization 4868
        transport 4542
          monoatomic ion transport 1254
            monoatomic cation transport 1051
              metal ion transport 899
                calcium ion transport 440
                  regulation of calcium ion transport 271
                    negative regulation of calcium ion transport 59
                      negative regulation of calcium ion transmembrane transport 35
                        negative regulation of calcium import into the mitochondrion 2
                        negative regulation of calcium ion export across plasma membrane 3
                        negative regulation of calcium ion import across plasma membrane 4
                        negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel 5
                        negative regulation of calcium ion transmembrane transporter activity + 6
                        negative regulation of calcium ion transport into cytosol + 4
                        negative regulation of release of sequestered calcium ion into cytosol + 9
paths to the root