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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of autophagy of mitochondrion
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Accession:GO:1903146 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of mitochondrion degradation by an autophagic process.
Synonyms:broad_synonym: regulation of mitochondrion degradation


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negative regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec16a C-type lectin domain containing 16A acts_upstream_of_or_within ISO (PMID:24949970) MGI PMID:24949970 NCBI chrNW_004936530:9,089,478...9,264,563
Ensembl chrNW_004936530:9,089,476...9,264,592
JBrowse link
G Fbxl4 F-box and leucine rich repeat protein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936651:530,296...609,443
Ensembl chrNW_004936651:530,197...609,417
JBrowse link
G Pink1 PTEN induced kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:6,574,471...6,589,478
Ensembl chrNW_004936474:6,573,623...6,589,478
JBrowse link
G Pptc7 protein phosphatase targeting COQ7 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936558:3,491,225...3,531,886
Ensembl chrNW_004936558:3,490,808...3,532,345
JBrowse link
G Rnf41 ring finger protein 41 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:24949970) Ensembl
MGI
PMID:24949970 GO_REF:0000107 NCBI chrNW_004936646:605,302...630,645
Ensembl chrNW_004936646:605,302...631,022
JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22044588) Ensembl
MGI
PMID:22044588 GO_REF:0000107 NCBI chrNW_004936606:4,518,525...4,540,109
Ensembl chrNW_004936606:4,518,584...4,540,114
JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22044588) Ensembl
MGI
PMID:22044588 GO_REF:0000107 NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425
JBrowse link
G Tspo translocator protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936718:992,301...995,172
Ensembl chrNW_004936718:992,301...995,995
JBrowse link
G Usp30 ubiquitin specific peptidase 30 ISO RGD PMID:24896179 RGD:13208875 NCBI chrNW_004936769:874,188...902,690
Ensembl chrNW_004936769:826,615...904,034
JBrowse link
negative regulation of type 2 mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htra2 HtrA serine peptidase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936556:741,718...746,016
Ensembl chrNW_004936556:741,718...749,090
JBrowse link
G Vps13c vacuolar protein sorting 13 homolog C involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936471:22,661,899...22,842,144
Ensembl chrNW_004936471:22,661,447...22,842,150
JBrowse link
positive regulation of autophagy of mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bnip3 BCL2 interacting protein 3 ISO RGD PMID:23698117 RGD:11561968 NCBI chrNW_004936486:18,449,371...18,460,435
Ensembl chrNW_004936486:18,448,494...18,455,927
JBrowse link
G Fbxo7 F-box protein 7 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936492:7,261,442...7,276,779
Ensembl chrNW_004936492:7,261,009...7,276,943
JBrowse link
positive regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ambra1 autophagy and beclin 1 regulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936562:2,493,823...2,676,868
Ensembl chrNW_004936562:2,493,774...2,676,912
JBrowse link
G Atg7 autophagy related 7 ISO RGD PMID:37042059 RGD:407532700 NCBI chrNW_004936602:1,938,720...2,179,239
Ensembl chrNW_004936602:1,935,507...2,179,256
JBrowse link
G Cers1 ceramide synthase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936596:2,442,978...2,467,184
Ensembl chrNW_004936596:2,442,991...2,467,184
JBrowse link
G Dele1 DAP3 binding cell death enhancer 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936504:12,247,584...12,259,962
Ensembl chrNW_004936504:12,245,776...12,259,851
JBrowse link
G Eif2ak1 eukaryotic translation initiation factor 2 alpha kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936750:389,913...430,783
Ensembl chrNW_004936750:389,845...432,460
JBrowse link
G Fbxo7 F-box protein 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936492:7,261,442...7,276,779
Ensembl chrNW_004936492:7,261,009...7,276,943
JBrowse link
G LOC101966195 huntingtin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936477:20,443,101...20,577,167
Ensembl chrNW_004936477:20,443,113...20,577,071
Ensembl chrNW_004936477:20,443,113...20,577,071
JBrowse link
G LOC101972667 immunity related GTPase M involved_in ISO (PMID:21102437), (PMID:32939830)
(PMID:33510463)
UniProt PMID:21102437 PMID:32939830 PMID:33510463 NCBI chrNW_004936504:4,055,091...4,056,089 JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:3,708,069...3,742,845
Ensembl chrNW_004936475:3,713,362...3,745,982
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
IEA
RGD
Ensembl
PMID:28608965 GO_REF:0000107 RGD:13432560 NCBI chrNW_004936489:12,118,538...12,913,664
Ensembl chrNW_004936489:12,120,678...13,327,872
JBrowse link
G Slc25a4 solute carrier family 25 member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936554:4,130,461...4,135,046
Ensembl chrNW_004936554:4,130,459...4,135,044
JBrowse link
G Slc25a5 solute carrier family 25 member 5 involved_in ISO (PMID:31618756) UniProt PMID:31618756 NCBI chrNW_004936479:10,432,172...10,435,154 JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 involved_in ISO PMID:29934347 UniProt PMID:29934347 RGD:405650300 NCBI chrNW_004936501:328,767...330,963
Ensembl chrNW_004936501:326,451...330,983
JBrowse link
G Ube2a ubiquitin conjugating enzyme E2 A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936479:10,330,666...10,340,268
Ensembl chrNW_004936479:10,330,632...10,340,367
JBrowse link
G Vps13d vacuolar protein sorting 13 homolog D involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:955,081...1,194,200
Ensembl chrNW_004936474:955,040...1,195,859
JBrowse link
positive regulation of type 2 mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp5if1 ATP synthase inhibitory factor subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:12,396,416...12,399,760
Ensembl chrNW_004936474:12,396,023...12,401,023
JBrowse link
G Cdc37 cell division cycle 37, HSP90 cochaperone involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936659:711,165...721,207
Ensembl chrNW_004936659:711,117...721,260
JBrowse link
G Gba1 glucosylceramidase beta 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:23707074) Ensembl
ARUK-UCL
PMID:23707074 GO_REF:0000107 NCBI chrNW_004936580:4,715,869...4,720,752
Ensembl chrNW_004936580:4,715,408...4,720,798
JBrowse link
G Hdac6 histone deacetylase 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936721:757,500...778,416
Ensembl chrNW_004936721:758,181...778,053
JBrowse link
G Hk2 hexokinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936556:1,054,143...1,113,425
Ensembl chrNW_004936556:1,054,021...1,113,450
JBrowse link
G Huwe1 HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936751:478,978...622,818
Ensembl chrNW_004936751:478,300...622,820
JBrowse link
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:6,479,640...6,486,080
Ensembl chrNW_004936474:6,477,504...6,486,660
JBrowse link
G Pink1 PTEN induced kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:6,574,471...6,589,478
Ensembl chrNW_004936474:6,573,623...6,589,478
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936489:12,118,538...12,913,664
Ensembl chrNW_004936489:12,120,678...13,327,872
JBrowse link
G Tomm7 translocase of outer mitochondrial membrane 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936478:30,787...36,952
Ensembl chrNW_004936478:30,666...37,062
JBrowse link
G Vdac1 voltage dependent anion channel 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936647:1,220,075...1,249,579
Ensembl chrNW_004936647:1,230,450...1,249,814
JBrowse link
regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy10 adenylate cyclase 10 ISO RGD PMID:31172217 RGD:329403053 NCBI chrNW_004936481:18,274,158...18,330,136
Ensembl chrNW_004936481:18,274,154...18,330,173
JBrowse link
G Bnip3l BCL2 interacting protein 3 like involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936757:499,485...523,494
Ensembl chrNW_004936757:499,147...523,541
JBrowse link
G Csnk2a2 casein kinase 2 alpha 2 involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chrNW_004936475:10,030,408...10,073,576
Ensembl chrNW_004936475:10,033,717...10,075,511
JBrowse link
G Cttn cortactin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936599:481,234...503,857
Ensembl chrNW_004936599:481,243...501,743
JBrowse link
G Dnm1l dynamin 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936607:3,576,357...3,632,423
Ensembl chrNW_004936607:3,576,392...3,632,554
JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936689:2,261,163...2,449,951
Ensembl chrNW_004936689:2,259,477...2,344,764
JBrowse link
G Fkbp8 FKBP prolyl isomerase 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936596:2,728,089...2,735,718
Ensembl chrNW_004936596:2,728,114...2,735,317
JBrowse link
G Fzd5 frizzled class receptor 5 involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chrNW_004936631:3,909,046...3,915,939
Ensembl chrNW_004936631:3,911,693...3,915,560
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936706:266,462...277,256
Ensembl chrNW_004936706:269,126...277,256
JBrowse link
G Parl presenilin associated rhomboid like involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936578:5,945,765...5,992,972
Ensembl chrNW_004936578:5,945,635...5,993,143
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936741:1,408,669...1,419,717
Ensembl chrNW_004936741:1,406,521...1,419,776
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chrNW_004936492:115,923...174,614
Ensembl chrNW_004936492:115,821...174,775
JBrowse link
G Usp36 ubiquitin specific peptidase 36 involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chrNW_004936594:3,194,842...3,228,701
Ensembl chrNW_004936594:3,194,482...3,228,748
JBrowse link
G Vdac1 voltage dependent anion channel 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936647:1,220,075...1,249,579
Ensembl chrNW_004936647:1,230,450...1,249,814
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17413
    cellular process 17016
      process utilizing autophagic mechanism 515
        autophagy 515
          regulation of autophagy 315
            regulation of autophagy of mitochondrion 49
              negative regulation of autophagy of mitochondrion + 11
              positive regulation of autophagy of mitochondrion + 26
              regulation of mitophagy + 48
Path 2
Term Annotations click to browse term
  biological_process 17413
    biological regulation 11405
      regulation of biological process 11039
        regulation of cellular process 10717
          regulation of metabolic process 5915
            regulation of catabolic process 1001
              regulation of autophagy 315
                regulation of autophagy of mitochondrion 49
                  negative regulation of autophagy of mitochondrion + 11
                  positive regulation of autophagy of mitochondrion + 26
                  regulation of mitophagy + 48
paths to the root